AMD Instinct MI300X vs NVIDIA GeForce RTX 5080 SUPER Comparison

FAQ

Q: What is the performance difference between the AMD Instinct MI300X and the NVIDIA GeForce RTX 5080 SUPER?

A: The two GPUs cannot be compared directly through a common benchmark suite. The AMD Instinct MI300X records an average benchmark score of 317,994 in Geekbench OpenCL, while the NVIDIA GeForce RTX 5080 SUPER records an average score of 3,075 in 3DMark Steel Nomad DX12. The head-to-head benchmark list is empty, so no direct cross-test scores exist.

Q: What are the nearest rivals for the AMD Instinct MI300X?

A: The database places the NVIDIA H200 NVL 5% above it with a score of 334,891, the NVIDIA B200 8% above with 345,482, the NVIDIA L40S 7.5% below with 295,763, and the NVIDIA RTX 6000 Ada Generation 10.7% below with 287,237.

Q: What are the nearest rivals for the NVIDIA GeForce RTX 5080 SUPER?

A: The recorded rivals include the Intel Arc Pro B60 which is 3.4% above with a score of 3,182, the NVIDIA Quadro P1000 which is 2.8% above with 3,163, the NVIDIA GeForce 820A which is 3.1% below with 2,983, and the NVIDIA GeForce GTX 860M which is 3.6% below with 2,967.

Q: What memory configurations do these two cards use?

A: The AMD Instinct MI300X uses 192 GB of HBM3 on an 8192-bit bus with 5.32 TB/s bandwidth. The NVIDIA GeForce RTX 5080 SUPER uses 24 GB of GDDR7 on a 256-bit bus with 1.02 TB/s bandwidth.

Q: What is the launch MSRP of the NVIDIA GeForce RTX 5080 SUPER?

A: The launch MSRP is 999 USD. The AMD Instinct MI300X has no recorded launch MSRP in the database.

Q: What is the transistor count difference between the two chips?

A: The AMD Instinct MI300X contains 153,000 million transistors on a 1017 mm² die, while the NVIDIA GeForce RTX 5080 SUPER contains 45,600 million transistors on a 378 mm² die.

Architecture Differences

The AMD Instinct MI300X is built on the CDNA 3.0 architecture, while the NVIDIA GeForce RTX 5080 SUPER uses Blackwell 2.0. The MI300X uses the Aqua Vanjaram chip, whereas the RTX 5080 SUPER uses the GB203 chip. Both are manufactured on a 5 nm process at TSMC, but the MI300X has a much larger die at 1017 mm² compared to 378 mm² for the RTX 5080 SUPER. Transistor density also differs: the MI300X reaches 150.4M transistors per mm², while the RTX 5080 SUPER achieves 120.6M per mm².

The MI300X has 19,456 shading units and 1,216 texture mapping units, but no ROPs, no ray tracing cores, and no tensor cores. Its pixel rate is 0 MPixel/s, and texture rate is 2,553.6 GTexel/s. In contrast, the RTX 5080 SUPER has 10,752 shading units, 336 TMUs, 112 ROPs, 84 ray tracing cores, and 336 tensor cores. Its pixel rate is 293.1 GPixel/s and texture rate is 879.3 GTexel/s.

Memory architecture differs substantially. The MI300X uses 192 GB of HBM3 with an 8192-bit bus and 5.32 TB/s bandwidth. The RTX 5080 SUPER uses 24 GB of GDDR7 with a 256-bit bus and 1.02 TB/s bandwidth. The MI300X has no display outputs, while the RTX 5080 SUPER provides 1x HDMI 2.1b and 3x DisplayPort 2.1b outputs.

API support also separates the two. The MI300X records N/A for DirectX, OpenGL, and Vulkan. The RTX 5080 SUPER supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4.

Clock behavior differs as well. The MI300X has a base clock of 1000 MHz and a boost clock of 2100 MHz, with memory at 1300 MHz (5.2 Gbps effective). The RTX 5080 SUPER runs at a base clock of 2295 MHz and boost of 2617 MHz, with memory at 2000 MHz (32 Gbps effective).

Power and physical design diverge. The MI300X has a TDP of 750 W, uses an OAM Module slot width, and has no power connectors. The RTX 5080 SUPER has a TDP of 415 W, is dual-slot, uses 1x 16-pin power connector, and measures 304 mm in length, 137 mm in height, and 40 mm in width.

Head-to-Head Benchmarks

The database records no direct head-to-head benchmark results between the AMD Instinct MI300X and the NVIDIA GeForce RTX 5080 SUPER. The winsA and winsB fields are both 0. This means no single test pits the two against each other under identical conditions.

However, each card has its own benchmark record. The MI300X delivers a Geekbench OpenCL score of 317,994, which places it at the 100th percentile among all GPUs in the database. The RTX 5080 SUPER delivers a 3DMark Steel Nomad DX12 score of 3,075, placing it at the 19th percentile among all GPUs.

The MI300X's nearest rivals in its benchmark category show a tight cluster. The NVIDIA H200 NVL scores 334,891 (5% higher), the NVIDIA B200 scores 345,482 (8% higher), the NVIDIA L40S scores 295,763 (7.5% lower), and the NVIDIA RTX 6000 Ada Generation scores 287,237 (10.7% lower). This places the MI300X in the upper tier of data center accelerators, with only two recorded rivals above it.

The RTX 5080 SUPER's nearest rivals in its benchmark category cluster within a narrow band. The Intel Arc Pro B60 scores 3,182 (3.4% higher), the NVIDIA Quadro P1000 scores 3,163 (2.8% higher), the NVIDIA GeForce 820A scores 2,983 (3.1% lower), and the NVIDIA GeForce GTX 860M scores 2,967 (3.6% lower). This indicates the RTX 5080 SUPER sits in a mid-range position for its test, with rivals on both sides within roughly 3.6%.

Because the benchmark tests differ (OpenCL versus 3DMark Steel Nomad DX12) and the head-to-head list is empty, the data does not support a direct performance comparison. The MI300X's score is orders of magnitude higher numerically, but that reflects the different test methodology and workload, not necessarily superior raw speed relative to the RTX 5080 SUPER in the same task.

The Verdict

The data shows two products designed for entirely different purposes. The AMD Instinct MI300X is a compute accelerator with no display outputs, no ray tracing hardware, and no consumer API support. Its 192 GB of HBM3 memory and 5.32 TB/s bandwidth position it for large-scale data center workloads. Its benchmark record in Geekbench OpenCL, scoring 317,994 and ranking at the 100th percentile, confirms it as a top-tier compute device among all GPUs in the database.

The NVIDIA GeForce RTX 5080 SUPER is a consumer graphics card with display outputs, ray tracing cores, tensor cores, and full DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4 support. Its 24 GB of GDDR7 memory and 1.02 TB/s bandwidth serve gaming and workstation graphics tasks. Its 3DMark Steel Nomad DX12 score of 3,075 places it at the 19th percentile, indicating it sits below many other GPUs in that specific test.

The recorded data does not allow a direct winner. The MI300X dominates in memory capacity, bandwidth, shading units, texture rate, and transistor count. The RTX 5080 SUPER leads in clock speeds, has ROPs, ray tracing cores, tensor cores, pixel rate, and display connectivity. For compute-oriented workloads without graphics output, the MI300X is the clear choice based on its massive memory and texture throughput. For graphics rendering, ray tracing, and consumer display tasks, the RTX 5080 SUPER is the only option of the two that supports such features.

Specification Differences

The two cards differ in nearly every recorded specification field:

• Chip: Aqua Vanjaram (MI300X) versus GB203 (RTX 5080 SUPER)
• Architecture: CDNA 3.0 versus Blackwell 2.0
• Transistors: 153,000 million versus 45,600 million
• Die size: 1017 mm² versus 378 mm²
• Transistor density: 150.4M / mm² versus 120.6M / mm²
• Base clock: 1000 MHz versus 2295 MHz
• Boost clock: 2100 MHz versus 2617 MHz
• Memory clock: 1300 MHz 5.2 Gbps effective versus 2000 MHz 32 Gbps effective
• Memory size: 192 GB versus 24 GB
• Memory type: HBM3 versus GDDR7
• Memory bus width: 8192 bit versus 256 bit
• Memory bandwidth: 5.32 TB/s versus 1.02 TB/s
• Shading units: 19,456 versus 10,752
• TMUs: 1,216 versus 336
• ROPs: 0 versus 112
• Ray tracing cores: None versus 84
• Tensor cores: None versus 336
• Pixel rate: 0 MPixel/s versus 293.1 GPixel/s
• Texture rate: 2,553.6 GTexel/s versus 879.3 GTexel/s
• FP32: 81.72 TFLOPS versus 56.28 TFLOPS
• FP16: 81.72 TFLOPS (1:1) versus 56.28 TFLOPS (1:1)
• TDP: 750 W versus 415 W
• Slot width: OAM Module versus Dual-slot
• Power connectors: None versus 1x 16-pin
• Suggested PSU: 1150 W versus not recorded
• Display outputs: No outputs versus 1x HDMI 2.1b, 3x DisplayPort 2.1b
• DirectX support: N/A versus 12 Ultimate (12_2)
• OpenGL support: N/A versus 4.6
• Vulkan support: N/A versus 1.4
• Dimensions: Not recorded versus 304 mm length, 137 mm height, 40 mm width
• Production status: Not recorded versus Active
• Release date: 2023-12-05 versus 2025-12-31
• Launch MSRP: Not recorded versus 999 USD

Where Each One Wins

The AMD Instinct MI300X wins in raw compute capacity. It delivers 81.72 TFLOPS in both FP32 and FP16, compared to 56.28 TFLOPS for the RTX 5080 SUPER. Its texture rate of 2,553.6 GTexel/s is nearly three times the RTX 5080 SUPER's 879.3 GTexel/s. The MI300X also holds a massive memory advantage: 192 GB versus 24 GB, with 5.32 TB/s bandwidth versus 1.02 TB/s. Its 19,456 shading units and 1,216 TMUs dwarf the RTX 5080 SUPER's 10,752 and 336 respectively.

The MI300X's benchmark percentile of 100 among all GPUs indicates it outperforms every other recorded device in its Geekbench OpenCL test. Its nearest rivals, the NVIDIA B200 and H200 NVL, sit only 8% and 5% above it, while the L40S and RTX 6000 Ada Generation fall 7.5% and 10.7% below.

The NVIDIA GeForce RTX 5080 SUPER wins in graphics-specific features. It has 112 ROPs, 84 ray tracing cores, and 336 tensor cores, none of which exist on the MI300X. Its pixel rate of 293.1 GPixel/s enables rasterization work that the MI300X cannot perform. Clock speeds are also higher: 2295 MHz base and 2617 MHz boost versus 1000 MHz and 2100 MHz. The memory clock of 2000 MHz (32 Gbps effective) is faster than the MI300X's 1300 MHz (5.2 Gbps effective).

The RTX 5080 SUPER provides display connectivity with 1x HDMI 2.1b and 3x DisplayPort 2.1b, while the MI300X has no outputs. API support for DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4 makes the RTX 5080 SUPER suitable for consumer software, whereas the MI300X records N/A for all three APIs.

In its own benchmark, the RTX 5080 SUPER's 3DMark Steel Nomad DX12 score of 3,075 places it at the 19th percentile, below the majority of GPUs in that test. Its nearest rivals are tightly packed, with the Intel Arc Pro B60 and NVIDIA Quadro P1000 slightly above, and the GeForce 820A and GTX 860M slightly below.

The RTX 5080 SUPER also wins on power efficiency per the recorded data. Its TDP of 415 W is substantially lower than the MI300X's 750 W. Physical form factor differs as well: the RTX 5080 SUPER is a dual-slot card with a 16-pin connector, while the MI300X is an OAM module with no power connectors and a suggested PSU of 1150 W.

The release timeline separates them by two years: the MI300X launched on 2023-12-05, and the RTX 5080 SUPER launched on 2025-12-31. The RTX 5080 SUPER has an active production status, while the MI300X's production status is not recorded.