AMD Radeon RX 6750 GRE 12 GB vs NVIDIA Quadro M6000 Comparison

The Verdict

The AMD Radeon RX 6750 GRE 12 GB and the NVIDIA Quadro M6000 are two graphics cards from completely different eras and design goals. The database shows a single direct comparison in Geekbench Vulkan, where the AMD card wins decisively, but the overall average benchmark scores tell a broader story. The RX 6750 GRE 12 GB holds an average benchmark score of 55698, while the Quadro M6000 sits at 43301, a gap of roughly 28.6% in favor of the AMD part. The AMD card also ranks in the 87th percentile of all GPUs, versus the 84th percentile for the NVIDIA card.

For a modern gaming or general-purpose DirectX 12 workload, the RX 6750 GRE 12 GB is the clear choice. Its architecture, clock speeds, and raw compute throughput are far ahead. For legacy professional applications that rely on OpenGL or specific Maxwell-era optimizations, the Quadro M6000 still functions, but its end-of-life status and older feature set make it a poor pick for new builds. The data suggests that anyone building a new system today should choose the AMD card, while the Quadro M6000 is only relevant for maintaining an existing legacy workstation.

Where Each One Wins

The AMD Radeon RX 6750 GRE 12 GB wins the only head-to-head benchmark recorded in the database: Geekbench Vulkan, with a score of 108994 against 46913, a massive 132.3% advantage. This is expected given the architectural generational gap. The AMD card also leads heavily in theoretical peak FP32 performance, rated at 13.21 TFLOPS versus 6.844 TFLOPS for the Quadro M6000. Its pixel rate of 165.2 GPixel/s and texture rate of 413.0 GTexel/s also dwarf the NVIDIA card's 106.9 GPixel/s and 213.9 GTexel/s, respectively.

The NVIDIA Quadro M6000 does not win any recorded benchmark against the AMD card. However, its strengths lie in raw resources: it has more shading units (3072 versus 2560), more texture mapping units (192 versus 160), more render output units (96 versus 64), and a wider 384-bit memory bus. Its GDDR5 memory bandwidth of 317.4 GB/s is lower than the AMD card's 432.0 GB/s, but the wider bus can help in specific legacy compute patterns that favor memory parallelism over raw speed.

Architecture Differences

The two cards are built on fundamentally different architectures and process nodes. The AMD Radeon RX 6750 GRE 12 GB uses the Navi 22 chip on the RDNA 2.0 architecture, fabricated on a 7 nm TSMC process. It packs 17,200 million transistors into a 335 mm² die, yielding a transistor density of 51.3M per mm². The NVIDIA Quadro M6000 uses the GM200 chip on the Maxwell 2.0 architecture, built on a 28 nm TSMC process. It contains 8,000 million transistors on a much larger 601 mm² die, with a transistor density of only 13.3M per mm².

This node advantage explains the massive clock speed difference. The AMD card runs at a base clock of 2321 MHz and boosts to 2581 MHz, while the Quadro M6000 operates at 988 MHz base and 1114 MHz boost. The AMD card also features 40 dedicated ray tracing cores, which the Quadro M6000 lacks entirely. The AMD card supports DirectX 12 Ultimate (12_2), while the Quadro M6000 only supports DirectX 12 (12_1). Both support OpenGL 4.6 and Vulkan 1.4.

Memory technology also differs: the AMD card uses 12 GB of GDDR6 on a 192-bit bus, while the Quadro M6000 uses 12 GB of GDDR5 on a 384-bit bus. The AMD card's memory runs at 18 Gbps effective, versus 6.6 Gbps for the NVIDIA card. This leads to the AMD card's higher bandwidth of 432.0 GB/s, despite the narrower bus.

FAQ

Q: Which card has higher raw compute performance (FP32)?

A: The AMD Radeon RX 6750 GRE 12 GB is far ahead, rated at 13.21 TFLOPS FP32, while the NVIDIA Quadro M6000 is at 6.844 TFLOPS.

Q: Does the Quadro M6000 have more memory?

A: Both cards have 12 GB of memory, but the AMD card uses faster GDDR6 on a 192-bit bus, while the NVIDIA card uses GDDR5 on a 384-bit bus.

Q: Which card supports ray tracing?

A: Only the AMD Radeon RX 6750 GRE 12 GB has dedicated ray tracing cores (40 of them). The NVIDIA Quadro M6000 has no ray tracing hardware.

Q: What is the production status of each card?

A: The AMD Radeon RX 6750 GRE 12 GB is listed as Active, while the NVIDIA Quadro M6000 is End-of-life.

Q: How do their average benchmark scores compare?

A: The AMD card averages 55698 across all recorded benchmarks, while the Quadro M6000 averages 43301, making the AMD card approximately 28.6% faster on average.

Q: Which card has a higher pixel fill rate?

A: The AMD card achieves 165.2 GPixel/s, compared to 106.9 GPixel/s for the NVIDIA card.

Head-to-Head Benchmarks

The database records exactly one direct head-to-head benchmark between these two cards: Geekbench Vulkan. The AMD Radeon RX 6750 GRE 12 GB scored 108994, while the NVIDIA Quadro M6000 scored 46913. This yields a delta of 132.3% in favor of the AMD card. This is not a narrow win; it is a generational obliteration. The AMD card's Vulkan performance is more than double that of the Quadro M6000.

Looking at the broader benchmark context, the AMD card's average score of 55698 places it near the AMD Radeon 8060S (55757, a delta of -0.1%), the NVIDIA GeForce RTX 5080 (56083, a delta of -0.7%), and ahead of the AMD Radeon Pro W5700X (54828, a delta of 1.6%) and the NVIDIA GeForce RTX 4080 (54247, a delta of 2.7%). The Quadro M6000's average score of 43301 places it near the NVIDIA GeForce RTX 5050 Mobile (43268, a delta of 0.1%), the NVIDIA Quadro M6000 24 GB (43262, a delta of 0.1%), and the NVIDIA GeForce RTX 4070 SUPER (43223, a delta of 0.2%), while being slightly behind the NVIDIA GeForce RTX 4090 Mobile (43667, a delta of -0.8%).

This means the AMD card competes with modern high-end consumer GPUs like the RTX 4080 and RTX 5080 in average score, while the Quadro M6000 competes with mid-range mobile parts like the RTX 5050 Mobile and RTX 4070 SUPER. The performance gap between the two cards is roughly equivalent to the difference between a flagship desktop GPU and a mid-range laptop GPU.

In terms of specific workload strengths, the AMD card's 13.21 TFLOPS FP32 and 26.43 TFLOPS FP16 (2:1) make it suited for compute-heavy tasks that leverage these rates. The Quadro M6000 has no recorded FP16 performance, which limits its usefulness in modern half-precision workloads. The AMD card's 40 ray tracing cores also provide hardware acceleration for DirectX 12 Ultimate titles, which the Quadro M6000 cannot do.

Specification Differences

The following specifications differ between the two cards:

• Process Node: AMD uses 7 nm, NVIDIA uses 28 nm.
• Transistors: AMD has 17,200 million, NVIDIA has 8,000 million.
• Die Size: AMD is 335 mm², NVIDIA is 601 mm².
• Transistor Density: AMD is 51.3M / mm², NVIDIA is 13.3M / mm².
• Base Clock: AMD is 2321 MHz, NVIDIA is 988 MHz.
• Boost Clock: AMD is 2581 MHz, NVIDIA is 1114 MHz.
• Game Clock: AMD has 2439 MHz, NVIDIA has no game clock.
• Memory Clock: AMD is 2250 MHz (18 Gbps effective), NVIDIA is 1653 MHz (6.6 Gbps effective).
• Memory Type: AMD uses GDDR6, NVIDIA uses GDDR5.
• Memory Bus Width: AMD is 192-bit, NVIDIA is 384-bit.
• Memory Bandwidth: AMD is 432.0 GB/s, NVIDIA is 317.4 GB/s.
• Shading Units: AMD has 2560, NVIDIA has 3072.
• Texture Mapping Units: AMD has 160, NVIDIA has 192.
• Render Output Units: AMD has 64, NVIDIA has 96.
• Ray Tracing Cores: AMD has 40, NVIDIA has none.
• Pixel Rate: AMD is 165.2 GPixel/s, NVIDIA is 106.9 GPixel/s.
• Texture Rate: AMD is 413.0 GTexel/s, NVIDIA is 213.9 GTexel/s.
• FP32 Performance: AMD is 13.21 TFLOPS, NVIDIA is 6.844 TFLOPS.
• FP16 Performance: AMD is 26.43 TFLOPS (2:1), NVIDIA has none.
• Power Connectors: AMD uses 1x 6-pin + 1x 8-pin, NVIDIA uses 1x 8-pin.
• Bus Interface: AMD is PCIe 4.0 x16, NVIDIA is PCIe 3.0 x16.
• Display Outputs: AMD has 1x HDMI 2.1 and 3x DisplayPort 1.4a, NVIDIA has 1x DVI and 4x DisplayPort 1.2.
• DirectX Support: AMD is 12 Ultimate (12_2), NVIDIA is 12 (12_1).
• Height: AMD is 110 mm, NVIDIA is 111 mm.
• Release Date: AMD is 2023-10-16, NVIDIA is 2015-03-20.
• Production Status: AMD is Active, NVIDIA is End-of-life.
• Predecessor: AMD is Navi, NVIDIA is Quadro Kepler.
• Successor: AMD is Navi III, NVIDIA is Quadro Pascal.

Shared specifications include 12 GB memory size, 250 W TDP, dual-slot width, 600 W suggested PSU, 267 mm length, OpenGL 4.6, Vulkan 1.4, and a null codename. The AMD card's launch MSRP is 334 USD.