AMD Radeon RX 9070 GRE vs NVIDIA Quadro GP100 Comparison

The Verdict

The AMD Radeon RX 9070 GRE is the definitive performance leader in this comparison. The recorded data shows a decisive win in the single shared benchmark, with the RX 9070 GRE scoring 109309 points against the NVIDIA Quadro GP100's 87445 points, a 20% advantage. The Quadro GP100, while still a capable compute card, is an end-of-life product from 2016, and its benchmark percentile (93rd) is higher than the RX 9070 GRE's (87th), but that percentile reflects its standing across all GPUs in the database, not a direct comparison. The RX 9070 GRE belongs to an active product generation, offers modern API support including DirectX 12 Ultimate and Vulkan 1.4, and is the clear choice for anyone prioritizing raw OpenCL compute performance. The Quadro GP100 may appeal to those needing its specific 16 GB HBM2 memory configuration with a 4096-bit bus, but its compute scores are lower. The RX 9070 GRE is the pick for modern workloads, while the Quadro GP100 is only relevant for legacy compatibility or specific HBM2 memory requirements.

Architecture Differences

The two cards represent vastly different eras of GPU design. The NVIDIA Quadro GP100 uses the Pascal architecture, built on a 16 nm process at TSMC. It packs 15,300 million transistors on a 610 mm² die, resulting in a transistor density of 25.1 million per square millimeter. The chip is designated GP100. In contrast, the AMD Radeon RX 9070 GRE uses the RDNA 4.0 architecture, built on a 4 nm process, also at TSMC. It contains 53,900 million transistors on a 357 mm² die, achieving a density of 151.0 million per square millimeter. The chip is called Navi 48. This is a fundamental shift: the RX 9070 GRE packs more than three times the transistors into a smaller die.

Memory architecture is another major divergence. The Quadro GP100 uses 16 GB of HBM2 memory on a 4096-bit bus, delivering 732.2 GB/s of bandwidth. The RX 9070 GRE uses 12 GB of GDDR6 memory on a 192-bit bus, with 432.0 GB/s of bandwidth. The Quadro's memory bus is exceptionally wide, a hallmark of high-end compute cards of its generation, but the RX 9070 GRE compensates with much higher clock speeds. The Quadro's memory runs at 715 MHz (1430 Mbps effective), while the RX 9070 GRE's memory runs at 2250 MHz (18 Gbps effective).

Compute resources differ significantly. The Quadro GP100 has 3584 shading units, 224 texture mapping units, and 96 raster operations pipelines. It has no dedicated ray tracing or tensor cores. The RX 9070 GRE has 3072 shading units, 192 TMUs, 96 ROPs, and 48 ray tracing cores. Despite having fewer shading units, the RX 9070 GRE achieves much higher throughput due to its higher clocks. The Quadro's base clock is 1304 MHz with a boost of 1443 MHz, while the RX 9070 GRE has a base clock of 1420 MHz, a game clock of 2220 MHz, and a boost clock of 2790 MHz. This clock advantage translates directly into compute performance: the RX 9070 GRE delivers 34.28 TFLOPS FP32 and 34.28 TFLOPS FP16 (1:1), while the Quadro GP100 delivers 10.34 TFLOPS FP32 and 20.69 TFLOPS FP16 (2:1). The RX 9070 GRE also has higher pixel and texture rates: 267.8 GPixel/s and 535.7 GTexel/s versus 138.5 GPixel/s and 323.2 GTexel/s for the Quadro.

Power and interface differences are notable. The Quadro GP100 has a TDP of 235 W, uses a single 8-pin power connector, and suggests a 550 W power supply. It is a dual-slot card with a PCIe 3.0 x16 interface. The RX 9070 GRE has a TDP of 220 W, uses two 8-pin power connectors, also suggests a 550 W power supply, and is a dual-slot card with a PCIe 5.0 x16 interface. The RX 9070 GRE supports DirectX 12 Ultimate (12_2), while the Quadro supports DirectX 12 (12_1). Both support OpenGL 4.6, but the RX 9070 GRE supports Vulkan 1.4 versus the Quadro's Vulkan 1.3. Display outputs differ: the Quadro has 1x DVI and 4x DisplayPort 1.4a, while the RX 9070 GRE has 1x HDMI 2.1b and 3x DisplayPort 2.1a.

Where Each One Wins

The AMD Radeon RX 9070 GRE wins in the compute benchmark that both cards share. In Geekbench OpenCL, it scores 109309 against the Quadro's 87445, a 20% lead. This is the only head-to-head benchmark recorded in the database, and the RX 9070 GRE wins it outright. The RX 9070 GRE also wins on architectural modernity: it has ray tracing cores, a newer process node, higher clock speeds, and a more recent API feature set. Its 34.28 TFLOPS FP32 and FP16 performance is substantially higher than the Quadro's 10.34 TFLOPS FP32 and 20.69 TFLOPS FP16. For any workload that leverages FP32 compute, the RX 9070 GRE is clearly superior.

The NVIDIA Quadro GP100 does not win any recorded benchmark against the RX 9070 GRE. However, it has strengths that are not captured in the single shared test. Its 16 GB HBM2 memory with a 4096-bit bus and 732.2 GB/s bandwidth is a unique configuration. For workloads that are sensitive to memory bandwidth rather than raw compute, the Quadro's 732.2 GB/s could be advantageous, but the benchmark data does not include such a test. The Quadro also has a higher percentile ranking (93rd) compared to the RX 9070 GRE (87th), which suggests it performs well relative to the entire database of GPUs, even though it loses the direct comparison. The Quadro's end-of-life status and 2016 release date mean it is a legacy product, but its compute capabilities remain respectable. For users with specific HBM2 requirements or legacy software compatibility, the Quadro GP100 could still serve a purpose, but the benchmark data shows it is slower in OpenCL compute.

FAQ

Q: Which GPU has the higher OpenCL benchmark score?

A: The AMD Radeon RX 9070 GRE scores 109309 in Geekbench OpenCL, while the NVIDIA Quadro GP100 scores 87445. The RX 9070 GRE is 20% faster in this test.

Q: What are the memory configurations of each card?

A: The Quadro GP100 has 16 GB of HBM2 memory on a 4096-bit bus with 732.2 GB/s bandwidth. The RX 9070 GRE has 12 GB of GDDR6 memory on a 192-bit bus with 432.0 GB/s bandwidth.

Q: Do both cards support ray tracing?

A: No. The RX 9070 GRE has 48 ray tracing cores. The Quadro GP100 has no ray tracing cores.

Q: Which card has a higher FP32 throughput?

A: The RX 9070 GRE delivers 34.28 TFLOPS FP32, while the Quadro GP100 delivers 10.34 TFLOPS FP32. The RX 9070 GRE is significantly faster.

Q: What are the power requirements?

A: The Quadro GP100 has a TDP of 235 W and uses a single 8-pin power connector. The RX 9070 GRE has a TDP of 220 W and uses two 8-pin power connectors. Both suggest a 550 W power supply.

Q: Which card is currently in production?

A: The RX 9070 GRE is active, released on May 7, 2025. The Quadro GP100 is end-of-life, released on September 30, 2016.

Head-to-Head Benchmarks

The only direct benchmark recorded between the NVIDIA Quadro GP100 and the AMD Radeon RX 9070 GRE is Geekbench OpenCL. This test measures general-purpose compute performance using the OpenCL API, and it is a broad indicator of a GPU's ability to handle parallel workloads. The results are unambiguous. The AMD Radeon RX 9070 GRE scores 109309 points, while the NVIDIA Quadro GP100 scores 87445 points. The delta is exactly 20%, meaning the RX 9070 GRE is one-fifth faster than the Quadro GP100 in this workload.

This 20% advantage is substantial, and it aligns with the architectural differences between the two cards. The RX 9070 GRE's higher clock speeds, with a boost of 2790 MHz versus the Quadro's 1443 MHz, and its newer RDNA 4.0 architecture with 34.28 TFLOPS FP32, explain why it outperforms the older Pascal card. The Quadro's 16 GB HBM2 memory offers more capacity and bandwidth on paper, but the RX 9070 GRE's compute throughput overcomes that in this test.

Looking at the nearest rivals in the database provides context. The Quadro GP100's closest competitors, based on average benchmark scores, are the AMD Radeon PRO W7600 (87108, a 0.4% difference), the NVIDIA CMP 40HX (85637, a 2.1% difference), the NVIDIA RTX A4500 Mobile (91134, a -4% difference), and the NVIDIA RTX A4500 (91671, a -4.6% difference). The Quadro sits slightly above the PRO W7600 and CMP 40HX but trails the RTX A4500 variants. This places it in the mid-to-upper range of professional GPUs, but its 87445 OpenCL score is clearly below the RX 9070 GRE's 109309.

The RX 9070 GRE's nearest rivals include the Intel Arc A580 (57756, a -0.7% difference), the AMD Radeon RX 5600 OEM (58085, a -1.2% difference), the Intel Arc A570M (58239, a -1.5% difference), and the AMD Radeon RX 6950 XT (58392, a -1.8% difference). Note that these rival scores are average benchmark scores across multiple tests, not just OpenCL. The RX 9070 GRE's average benchmark score is 57367, which is lower than its OpenCL score because it also includes a 3DMark Steel Nomad DX12 score of 5424. This average places it in a competitive range with these other cards.

In the single head-to-head test, the RX 9070 GRE wins decisively. The 20% delta is a clear margin, and it reflects the fundamental generational gap between a 2016 Pascal compute card and a 2025 RDNA 4.0 graphics card. For OpenCL compute tasks, the RX 9070 GRE is the better choice by a significant margin. The Quadro GP100's strengths lie in its memory configuration and its historical position, but the benchmark data does not show it beating the RX 9070 GRE in any recorded test. The database records one win for the RX 9070 GRE and zero wins for the Quadro GP100.