AMD Radeon RX 6650M XT vs NVIDIA Quadro GP100 Comparison

NVIDIA Quadro GP100 and AMD Radeon RX 6650M XT occupy different corners of the GPU landscape, yet their benchmark scores place them within striking distance of each other. The data shows a clear winner in raw compute, but the architecture and feature set tell a more nuanced story. This analysis walks through the numbers, the silicon differences, and the practical implications for each card.

Head-to-Head Benchmarks

The only direct benchmark comparison available is the Geekbench OpenCL test, where the NVIDIA Quadro GP100 scores 87445 against the AMD Radeon RX 6650M XT’s 76904. That is a delta of 13.7%, putting the Quadro GP100 firmly ahead in this particular compute workload. The win is decisive but not overwhelming; it suggests a meaningful performance gap rather than a generational chasm.

Context from the nearest rivals sharpens the picture. The Quadro GP100 sits at the 93rd percentile of all GPUs, while the RX 6650M XT ranks at the 91st percentile. Both are high performers, but the Quadro’s score places it just 0.4% above the AMD Radeon PRO W7600 (87108) and 2.1% above the NVIDIA CMP 40HX (85637). It trails the NVIDIA RTX A4500 Mobile (91134) by 4% and the RTX A4500 (91671) by 4.6%. The RX 6650M XT, meanwhile, sits 1% above the NVIDIA GeForce RTX 5090 D (77712), 2.6% above the AMD Radeon RX 6850M XT (78940), and 3.1-3.4% above the Tesla P100 PCIe variants (79396 and 79605). These relative positions show the Quadro GP100 competing with professional workstation cards, while the RX 6650M XT trades blows with high-end consumer and data-center parts.

In this single test, the Quadro GP100 wins outright. The 13.7% delta is substantial enough to matter in compute-heavy workloads, but the RX 6650M XT’s lower score does not disqualify it—it remains a strong performer in its own percentile bracket.

Architecture Differences

The two GPUs are built on fundamentally different architectures and process nodes. The NVIDIA Quadro GP100 uses the GP100 chip, based on the Pascal architecture, manufactured on a 16 nm process at TSMC. It packs 15,300 million transistors onto a 610 mm² die, yielding a transistor density of 25.1 million per square millimeter. The AMD Radeon RX 6650M XT uses the Navi 23 chip, based on RDNA 2.0, also built by TSMC but on a 7 nm process. It has 11,060 million transistors on a 237 mm² die, giving a much higher density of 46.7 million per square millimeter. The process advantage is clear: AMD fits 30% fewer transistors into less than 40% of the die area.

Memory configurations diverge sharply. The Quadro GP100 offers 16 GB of HBM2 across a 4096-bit bus, delivering 732.2 GB/s of bandwidth. The RX 6650M XT has 8 GB of GDDR6 on a 128-bit bus, with 256.0 GB/s. That is a 2.86x bandwidth advantage for NVIDIA, which is critical for memory-bound tasks. Clock speeds tell the opposite story—the RX 6650M XT runs at a base of 2068 MHz and boosts to 2416 MHz, while the Quadro GP100 sits at 1304 MHz base and 1443 MHz boost. The AMD card’s higher clocks partially offset its narrower memory bus, but not enough to close the bandwidth gap.

Compute resources also differ. The Quadro GP100 has 3584 shading units, 224 texture mapping units, and 96 render output units. The RX 6650M XT has 2048 shading units, 128 TMUs, and 64 ROPs. NVIDIA’s raw unit counts are higher across the board, but AMD counters with 32 ray tracing cores—a feature the Pascal-based Quadro lacks entirely. Pixel rate favors AMD slightly (154.6 GPixel/s vs 138.5 GPixel/s), while texture rate is nearly identical (309.2 GTexel/s vs 323.2 GTexel/s). FP32 throughput is close: 10.34 TFLOPS for NVIDIA versus 9.896 TFLOPS for AMD. FP16 numbers are similarly matched at 20.69 TFLOPS and 19.79 TFLOPS, respectively, both operating at a 2:1 ratio.

Where Each One Wins

The Quadro GP100 wins in raw OpenCL compute, with a 13.7% margin in the Geekbench test. Its memory subsystem is the standout advantage—16 GB of HBM2 with 732.2 GB/s bandwidth dwarfs the RX 6650M XT’s 8 GB GDDR6 at 256.0 GB/s. For workloads that saturate memory bandwidth, such as large dataset processing or high-resolution rendering, the Quadro GP100 is the clear choice. Its 4096-bit bus is a professional-grade feature, and the 16 GB capacity handles larger working sets without spilling to system memory.

The RX 6650M XT wins on efficiency and modern features. Its 7 nm process and 120 W TDP contrast sharply with the Quadro GP100’s 235 W TDP—nearly half the power draw for 95.7% of the FP32 throughput. The 32 ray tracing cores provide hardware acceleration that the Quadro GP100 lacks, making it the better option for any workload involving ray-traced effects. Its PCIe 4.0 x8 interface doubles the per-lane bandwidth of the Quadro’s PCIe 3.0 x16, which can benefit data transfer in systems with fewer lanes. The IGP form factor and lack of power connectors also make it suitable for mobile or compact deployments, whereas the Quadro GP100 is a dual-slot card requiring a 550 W power supply and an 8-pin connector.

The Verdict

The data points to a clear split. For compute-heavy professional workloads where memory bandwidth and capacity are paramount, the NVIDIA Quadro GP100 is the superior choice. Its 13.7% OpenCL lead and 2.86x memory bandwidth advantage are decisive factors. The 16 GB HBM2 frame buffer is double the RX 6650M XT’s 8 GB, and the 4096-bit bus is unmatched in this comparison. The 93rd percentile ranking versus the 91st percentile confirms its higher overall standing.

For users prioritizing power efficiency, modern API support, or ray tracing, the AMD Radeon RX 6650M XT is the better fit. Its 120 W TDP is less than half the Quadro’s 235 W, and the RDNA 2.0 architecture brings DirectX 12 Ultimate (12_2) support and Vulkan 1.4, versus the Quadro’s DirectX 12 (12_1) and Vulkan 1.3. The 32 ray tracing cores are a hardware capability the Pascal architecture cannot offer. The 7 nm process also means a smaller die (237 mm² vs 610 mm²), which has implications for manufacturing efficiency even if both cards are end-of-life products.

FAQ

Q: Which GPU has higher OpenCL benchmark scores?

A: The NVIDIA Quadro GP100 scores 87445 in Geekbench OpenCL, which is 13.7% higher than the AMD Radeon RX 6650M XT’s 76904.

Q: What is the memory bandwidth difference between the two cards?

A: The Quadro GP100 has 732.2 GB/s of bandwidth from its 16 GB HBM2 memory on a 4096-bit bus. The RX 6650M XT offers 256.0 GB/s from 8 GB GDDR6 on a 128-bit bus, making NVIDIA’s bandwidth roughly 2.86 times higher.

Q: Does the RX 6650M XT have ray tracing support?

A: Yes, the AMD card includes 32 ray tracing cores as part of its RDNA 2.0 architecture. The NVIDIA Quadro GP100 has no ray tracing cores listed.

Q: How do the power requirements compare?

A: The Quadro GP100 has a 235 W TDP and requires a 550 W power supply with a single 8-pin connector. The RX 6650M XT has a 120 W TDP, uses no power connectors, and is listed as an IGP (integrated graphics processor) form factor.

Q: Which card has more shading units?

A: The NVIDIA Quadro GP100 has 3584 shading units, while the AMD Radeon RX 6650M XT has 2048. NVIDIA also has more TMUs (224 vs 128) and ROPs (96 vs 64).

Q: What are the pixel and texture rates for each card?

A: The Quadro GP100 has a pixel rate of 138.5 GPixel/s and a texture rate of 323.2 GTexel/s. The RX 6650M XT has a pixel rate of 154.6 GPixel/s and a texture rate of 309.2 GTexel/s. AMD leads in pixel rate, NVIDIA leads slightly in texture rate.

Specification Differences

| Specification | NVIDIA Quadro GP100 | AMD Radeon RX 6650M XT |

|---|---|---|

| Architecture | Pascal | RDNA 2.0 |

| Process Node | 16 nm | 7 nm |

| Transistors | 15,300 million | 11,060 million |

| Die Size | 610 mm² | 237 mm² |

| Transistor Density | 25.1M / mm² | 46.7M / mm² |

| Base Clock | 1304 MHz | 2068 MHz |

| Boost Clock | 1443 MHz | 2416 MHz |

| Memory Size | 16 GB | 8 GB |

| Memory Type | HBM2 | GDDR6 |

| Memory Bus Width | 4096 bit | 128 bit |

| Memory Bandwidth | 732.2 GB/s | 256.0 GB/s |

| Memory Clock | 1430 Mbps effective | 16 Gbps effective |

| Shading Units | 3584 | 2048 |

| TMUs | 224 | 128 |

| ROPs | 96 | 64 |

| Ray Tracing Cores | None | 32 |

| Pixel Rate | 138.5 GPixel/s | 154.6 GPixel/s |

| Texture Rate | 323.2 GTexel/s | 309.2 GTexel/s |

| FP32 Performance | 10.34 TFLOPS | 9.896 TFLOPS |

| FP16 Performance | 20.69 TFLOPS | 19.79 TFLOPS |

| TDP | 235 W | 120 W |

| Slot Width | Dual-slot | IGP |

| Power Connectors | 1x 8-pin | None |

| Suggested PSU | 550 W | None listed |

| Bus Interface | PCIe 3.0 x16 | PCIe 4.0 x8 |

| DirectX Support | 12 (12_1) | 12 Ultimate (12_2) |

| Vulkan Support | 1.3 | 1.4 |

| Display Outputs | 1x DVI, 4x DisplayPort 1.4a | Portable Device Dependent |

| Release Date | 2016-09-30 | 2022-01-03 |

| Generation | Quadro Pascal (Px000) | Navi Mobile (RX 6000M) |

| Predecessor | Quadro Maxwell | Polaris Mobile |

| Successor | Quadro Volta | None listed |

| Production Status | End-of-life | End-of-life |