AMD Instinct MI300X vs NVIDIA GeForce RTX 5080 Mobile Comparison

FAQ

Q: How does the AMD Instinct MI300X compare to the NVIDIA GeForce RTX 5080 Mobile in Geekbench OpenCL performance?

A: The AMD Instinct MI300X scores 317994, while the NVIDIA GeForce RTX 5080 Mobile scores 166986. The AMD part leads by 90.4% in this test.

Q: What is the percentile ranking of each GPU?

A: The AMD Instinct MI300X sits at the 100th percentile of all GPUs in the database, while the NVIDIA GeForce RTX 5080 Mobile sits at the 81st percentile.

Q: Which GPU has more memory and what type is used?

A: The AMD Instinct MI300X carries 192 GB of HBM3 on an 8192-bit bus, whereas the NVIDIA GeForce RTX 5080 Mobile carries 16 GB of GDDR7 on a 256-bit bus.

Q: What are the TDP ratings for these two accelerators?

A: The AMD Instinct MI300X is rated at 750 W, and the NVIDIA GeForce RTX 5080 Mobile is rated at 80 W.

Q: Which GPU has ray tracing and tensor cores?

A: Only the NVIDIA GeForce RTX 5080 Mobile lists 60 RT cores and 240 tensor cores. The AMD Instinct MI300X lists no RT cores and no tensor cores in the database.

Q: Does the AMD Instinct MI300X have any display outputs?

A: No. The AMD Instinct MI300X has no display outputs, while the NVIDIA GeForce RTX 5080 Mobile has outputs described as portable device dependent.

Architecture Differences

The two accelerators come from different design lineages. The AMD Instinct MI300X uses the Aqua Vanjaram chip built on CDNA 3.0, part of the Instinct (MIx) generation, and was released on 2023-12-05. The NVIDIA GeForce RTX 5080 Mobile uses the GB203 chip built on Blackwell 2.0, part of the GeForce 50 Mobile generation, and was released on 2025-04-01. Both are fabricated by TSMC on a 5 nm process node, but the transistor counts diverge sharply: the MI300X packs 153,000 million transistors on a 1017 mm² die, for a density of 150.4M / mm². The RTX 5080 Mobile packs 45,600 million transistors on a 378 mm² die, for a density of 120.6M / mm². The MI300X is the larger and denser chip by a wide margin.

The compute hierarchies also differ. The MI300X uses 19456 shading units and 1216 TMUs, with 0 ROPs recorded. The RTX 5080 Mobile uses 7680 shading units, 240 TMUs, and 96 ROPs. The NVIDIA part adds hardware for ray tracing and tensor operations: 60 RT cores and 240 tensor cores, none of which are listed for the AMD part. The AMD accelerator reports a pixel rate of 0 MPixel/s, consistent with its role as a compute card with no display outputs. The RTX 5080 Mobile reports 144.0 GPixel/s pixel rate and 360.0 GTexel/s texture rate, versus 2,553.6 GTexel/s for the MI300X.

API support separates the two as well. The RTX 5080 Mobile supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4. The MI300X lists N/A for DirectX, OpenGL, and Vulkan, confirming that it is not designed for conventional graphics rendering pipelines. The MI300X uses an OAM Module slot width, while the RTX 5080 Mobile is an IGP. Both use PCIe 5.0 x16 as the bus interface, and neither requires external power connectors in the recorded data, though the MI300X suggests a 1150 W PSU while the RTX 5080 Mobile has no suggested PSU listed.

Head-to-Head Benchmarks

The only directly comparable benchmark in the database is Geekbench OpenCL, where the AMD Instinct MI300X records 317994 against 166986 for the NVIDIA GeForce RTX 5080 Mobile. That is a 90.4% advantage for the AMD part, nearly doubling the NVIDIA score. The MI300X wins this head-to-head, and the database records 1 win for the AMD part and 0 wins for the NVIDIA part.

The MI300X sits at the 100th percentile of all GPUs, meaning it ranks above every other recorded device in the database. Its nearest rivals in average score are the NVIDIA B200 at 345482 (8% higher), the NVIDIA H200 NVL at 334891 (5% higher), the NVIDIA L40S at 295763 (7.5% lower), and the NVIDIA RTX 6000 Ada Generation at 287237 (10.7% lower). The MI300X trails the B200 and H200 NVL but leads the L40S and RTX 6000 Ada Generation. Its average benchmark score is 317994.

The RTX 5080 Mobile, by contrast, records an average benchmark score of 38349 across multiple tests including 3DMark Steel Nomad DX12 at 4952, Geekbench Vulkan at 169754, Passmark G3D at 27711, and Passmark GPU Compute at 12134. Its nearest rivals are clustered extremely close: the NVIDIA GeForce MX570 at 38299 (0.1% lower), the NVIDIA GeForce RTX 4080 Mobile at 38135 (0.6% lower), the NVIDIA GeForce MX570 A at 38691 (0.9% higher), and the AMD Radeon Pro 580X at 38706 (0.9% higher). The delta margins here are tiny, all under 1%, indicating that the RTX 5080 Mobile performs in a dense pack of mobile and workstation parts. The MI300X faces rival deltas of 5% to 10.7%, a much wider spread at the top of the performance distribution.

The OpenCL result is the only direct comparison available, and it favors the MI300X decisively. The RTX 5080 Mobile does not approach the MI300X compute output in this workload, and the 90.4% delta is the single largest win recorded in the head-to-head set.

Specification Differences

The table below lists only the fields where the two devices differ.

| Field | AMD Instinct MI300X | NVIDIA GeForce RTX 5080 Mobile |

|---|---|---|

| Series | None | GeForce 50-series |

| Manufacturer | AMD | NVIDIA |

| Chip | Aqua Vanjaram | GB203 |

| Architecture | CDNA 3.0 | Blackwell 2.0 |

| Generation | Instinct (MIx) | GeForce 50 Mobile |

| Transistors | 153,000 million | 45,600 million |

| Die Size | 1017 mm² | 378 mm² |

| Transistor Density | 150.4M / mm² | 120.6M / mm² |

| Base Clock | 1000 MHz | 975 MHz |

| Boost Clock | 2100 MHz | 1500 MHz |

| Memory Clock | 1300 MHz 5.2 Gbps effective | 1750 MHz 28 Gbps effective |

| Memory Size | 192 GB | 16 GB |

| Memory Type | HBM3 | GDDR7 |

| Memory Bus Width | 8192 bit | 256 bit |

| Memory Bandwidth | 5.32 TB/s | 896.0 GB/s |

| Shading Units | 19456 | 7680 |

| TMUs | 1216 | 240 |

| ROPs | 0 | 96 |

| RT Cores | None | 60 |

| Tensor Cores | None | 240 |

| Pixel Rate | 0 MPixel/s | 144.0 GPixel/s |

| Texture Rate | 2,553.6 GTexel/s | 360.0 GTexel/s |

| FP32 | 81.72 TFLOPS | 23.04 TFLOPS |

| FP16 | 81.72 TFLOPS (1:1) | 23.04 TFLOPS (1:1) |

| TDP | 750 W | 80 W |

| Slot Width | OAM Module | IGP |

| Suggested PSU | 1150 W | None |

| Display Outputs | No outputs | Portable Device Dependent |

| DirectX | N/A | 12 Ultimate (12_2) |

| OpenGL | N/A | 4.6 |

| Vulkan | N/A | 1.4 |

| Production Status | None | Active |

| Release Date | 2023-12-05 | 2025-04-01 |

| Predecessor | Radeon Instinct | GeForce 40 Mobile |

| Benchmarks | Geekbench OpenCL: 317994 | Multiple (3DMark, Geekbench, Passmark) |

| Percentile Vs All GPUs | 100 | 81 |

| Avg Benchmark Score | 317994 | 38349 |

Fields not listed, such as bus interface (PCIe 5.0 x16 for both), power connectors (None for both), foundry (TSMC for both), process node (5 nm for both), and launch MSRP (not recorded for either), are identical or unavailable.

The Verdict

The data places these two products in entirely different segments. The AMD Instinct MI300X is a 750 W OAM module with 192 GB of HBM3, 81.72 TFLOPS of FP32, and a 5.32 TB/s memory bus. It sits at the 100th percentile of all GPUs and dominates the single OpenCL comparison by 90.4%. Its nearest rivals are other data-center accelerators like the NVIDIA B200, H200 NVL, L40S, and RTX 6000 Ada Generation, and it beats two of those four in average score. The MI300X is not a graphics card: it has no display outputs, no graphics API support, and no ROPs. Every specification points to a compute-first accelerator for high-throughput workloads.

The NVIDIA GeForce RTX 5080 Mobile is an 80 W integrated graphics processor for portable devices. It carries 16 GB of GDDR7, 60 RT cores, 240 tensor cores, and full graphics API support including DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4. Its 81st percentile ranking and average score of 38349 place it in a very different performance class, one where its nearest rivals are the MX570, MX570 A, RTX 4080 Mobile, and Radeon Pro 580X, all within 1% of its average score. The RTX 5080 Mobile delivers 23.04 TFLOPS of FP32, 144.0 GPixel/s, and 360.0 GTexel/s, all far below the MI300X figures.

A buyer needing raw compute throughput, massive memory capacity, and top-of-database percentile placement should select the MI300X. A buyer needing a mobile part with graphics output, ray tracing, tensor cores, and low power draw should select the RTX 5080 Mobile. The two do not compete for the same workload, and the benchmark data reflects that separation. The MI300X wins the recorded head-to-head, but the RTX 5080 Mobile is the only one of the two with a graphics pipeline at all.