AMD Instinct MI300X vs NVIDIA GeForce RTX 4060 Comparison

Where Each One Wins

The recorded data presents a single head-to-head comparison point: Geekbench OpenCL. The AMD Instinct MI300X records a score of 317,994, while the NVIDIA GeForce RTX 4060 records 95,057. This yields a delta of 234.5% in favor of the AMD part. In this specific workload, the MI300X is the outright winner, and the RTX 4060 has no recorded benchmark win against it in the database.

However, the win distribution is heavily influenced by the scope of available tests. The MI300X has a single benchmark entry, the Geekbench OpenCL result, which also serves as its average benchmark score. The RTX 4060, in contrast, has a broader suite of recorded tests, including multiple Passmark DirectX variants, 3DMark Steel Nomad, Geekbench Vulkan, and Passmark compute tests. The RTX 4060’s wins are not against the MI300X directly, but rather in the breadth of its benchmark coverage. It has recorded scores in DirectX 9, 10, 11, and 12 scenarios, while the MI300X has no DirectX, OpenGL, or Vulkan API support recorded in the database. This means the MI300X cannot participate in those workloads at all, making the RTX 4060 the only option in those categories by default.

The performance profile of each card is also distinct. The MI300X delivers 81.72 TFLOPS of FP32 and FP16 (1:1) compute, while the RTX 4060 delivers 15.11 TFLOPS in both. The MI300X also has a massive memory subsystem: 192 GB of HBM3 on a 8192-bit bus, yielding 5.32 TB/s of bandwidth. The RTX 4060 uses 8 GB of GDDR6 on a 128-bit bus, with 272.0 GB/s. The MI300X is designed for compute density, with 19,456 shading units and 1,216 texture mapping units, but has zero ROPs and no display outputs. The RTX 4060 has 3,072 shading units, 96 TMUs, 48 ROPs, 24 RT cores, and 96 tensor cores, with full display output support.

The percentile rankings reinforce this split. The MI300X sits at the 100th percentile against all GPUs in the database, meaning it outperforms every other recorded GPU in its single benchmark. The RTX 4060, with an average score of 17,639, sits at the 61st percentile. This indicates that while the RTX 4060 is a mid-range performer in the overall database, the MI300X is an extreme outlier at the top end. The nearest rivals for the MI300X are all NVIDIA data center parts: the B200 at 345,482 (8% higher), the H200 NVL at 334,891 (5% higher), the L40S at 295,763 (7.5% lower), and the RTX 6000 Ada at 287,237 (10.7% lower). The RTX 4060’s nearest rivals are older or integrated parts: the HD 7790 at 17,666 (0.2% higher), the Radeon 780M at 17,588 (0.3% lower), and the Radeon Pro 560 and 460, which are within 0.7%.

The Verdict

The data indicates a complete divergence in purpose and capability. The AMD Instinct MI300X is a compute accelerator with an OAM module form factor, a 750 W TDP, and no display outputs or consumer API support. Its sole recorded benchmark, Geekbench OpenCL at 317,994, places it at the absolute top of the database’s GPU hierarchy. It is 234.5% ahead of the RTX 4060 in that test. Any workload that can leverage OpenCL compute and fit within the MI300X’s 192 GB HBM3 pool will see massive performance advantages. The RTX 4060, with a 115 W TDP, a dual-slot design, and a 299 USD launch MSRP, is a consumer graphics card. It has a full suite of API support, including DirectX 12 Ultimate, Vulkan 1.4, and OpenGL 4.6, plus display outputs for 1x HDMI 2.1 and 3x DisplayPort 1.4a. Its average benchmark score of 17,639 is about 5.5% of the MI300X’s score.

The choice is strictly workload-dependent. For compute-heavy tasks that are compatible with OpenCL and require massive memory bandwidth, the MI300X is the only viable option in this comparison. Its 5.32 TB/s bandwidth and 81.72 TFLOPS are unmatched by the RTX 4060. For rendering, gaming, or any task requiring rasterization, ray tracing, or display output, the RTX 4060 is the only card that has the necessary hardware. The MI300X has zero ROPs and a pixel rate of 0 MPixel/s, making it incapable of traditional graphics output. The RTX 4060, with 48 ROPs and a 118.1 GPixel/s pixel rate, handles those tasks, though its compute scores are far lower.

The percentile data also suggests different competitive contexts. The MI300X competes with the NVIDIA B200, H200 NVL, L40S, and RTX 6000 Ada, all of which are within 10.7% of its score. The RTX 4060 competes with the HD 7790 and Radeon 780M, which are within 0.7%. This places the MI300X in a class of top-tier accelerators, while the RTX 4060 sits in a mid-range consumer segment. The database shows no scenario where the RTX 4060 beats the MI300X in a shared benchmark, and no scenario where the MI300X can even run the RTX 4060’s tests.

Head-to-Head Benchmarks

The only direct head-to-head test is Geekbench OpenCL. The AMD Instinct MI300X scores 317,994, and the NVIDIA GeForce RTX 4060 scores 95,057. The delta is 234.5% in favor of the MI300X. This is the largest recorded single-test margin in the comparison, and it reflects the fundamental compute disparity between the two cards. The MI300X’s FP32 throughput of 81.72 TFLOPS is 5.4 times the RTX 4060’s 15.11 TFLOPS, and its memory bandwidth of 5.32 TB/s is 19.6 times the RTX 4060’s 272.0 GB/s. The Geekbench OpenCL score directly correlates with these specifications.

The RTX 4060 has no wins in the head-to-head data. However, the database records its performance in other tests that the MI300X cannot run. For instance, the RTX 4060 scores 2,302 in 3DMark Steel Nomad DX12, 48,643 in Geekbench Vulkan, and 19,545 in Passmark G3D. It also has Passmark scores for DirectX 9 (236), DirectX 10 (103), DirectX 11 (175), and DirectX 12 (76). These numbers are not comparable to the MI300X because the MI300X has no recorded results for these tests, and its API support is listed as N/A for DirectX, OpenGL, and Vulkan. The MI300X also has no display outputs, making any graphical benchmark impossible.

The texture and pixel rates further illustrate the divide. The MI300X has a texture rate of 2,553.6 GTexel/s, while the RTX 4060 has 236.2 GTexel/s. The MI300X’s pixel rate is 0 MPixel/s, while the RTX 4060’s is 118.1 GPixel/s. The MI300X has 1,216 TMUs, and the RTX 4060 has 96. The MI300X has no ROPs, and the RTX 4060 has 48. The MI300X’s shading unit count is 19,456 versus 3,072 for the RTX 4060. These numbers confirm that the MI300X is optimized for compute shader throughput, while the RTX 4060 is optimized for a balanced graphics pipeline.

FAQ

Q: Which GPU has the higher average benchmark score?

A: The AMD Instinct MI300X has an average benchmark score of 317,994, while the NVIDIA GeForce RTX 4060 has an average score of 17,639.

Q: How much faster is the MI300X in Geekbench OpenCL?

A: The MI300X scores 317,994 versus 95,057 for the RTX 4060, a 234.5% difference.

Q: Can the MI300X output video to a display?

A: No, the MI300X has no display outputs and a pixel rate of 0 MPixel/s. The RTX 4060 has 1x HDMI 2.1 and 3x DisplayPort 1.4a outputs.

Q: What memory configurations do the two cards use?

A: The MI300X uses 192 GB of HBM3 on a 8192-bit bus with 5.32 TB/s bandwidth. The RTX 4060 uses 8 GB of GDDR6 on a 128-bit bus with 272.0 GB/s bandwidth.

Q: What is the RTX 4060’s launch MSRP?

A: The RTX 4060 has a launch MSRP of 299 USD. The MI300X has no recorded launch MSRP.

Q: Which GPU has a higher percentile ranking in the database?

A: The MI300X is at the 100th percentile against all GPUs, while the RTX 4060 is at the 61st percentile.

Architecture Differences

The two GPUs come from different architectural lineages. The AMD Instinct MI300X uses the CDNA 3.0 architecture on the Aqua Vanjaram chip, built on a 5 nm TSMC process. It integrates 153,000 million transistors on a 1017 mm² die, yielding a transistor density of 150.4M per mm². The NVIDIA GeForce RTX 4060 uses the Ada Lovelace architecture on the AD107 chip, also on a 5 nm TSMC process. It integrates 18,900 million transistors on a 159 mm² die, yielding a density of 118.9M per mm². The MI300X’s die is 6.4 times larger and has 8.1 times more transistors.

Clock speeds differ significantly. The MI300X has a base clock of 1000 MHz and a boost clock of 2100 MHz. The RTX 4060 has a base clock of 1830 MHz and a boost clock of 2460 MHz. The RTX 4060 runs at higher clocks, but the MI300X compensates with far more compute units. The memory clocks also differ: the MI300X uses 1300 MHz with 5.2 Gbps effective, while the RTX 4060 uses 2125 MHz with 17 Gbps effective. The MI300X’s memory bandwidth advantage comes from its 8192-bit bus, not its clock speed.

The compute resource allocation is entirely different. The MI300X has 19,456 shading units, 1,216 TMUs, and 0 ROPs. It has no dedicated RT cores or tensor cores listed. The RTX 4060 has 3,072 shading units, 96 TMUs, 48 ROPs, 24 RT cores, and 96 tensor cores. The MI300X’s FP32 and FP16 throughput are both 81.72 TFLOPS (1:1 ratio), while the RTX 4060’s are both 15.11 TFLOPS (1:1 ratio). The MI300X’s texture rate is 2,553.6 GTexel/s, and the RTX 4060’s is 236.2 GTexel/s.

The power and form factor differences are stark. The MI300X has a TDP of 750 W, is an OAM Module, has no power connectors (likely using a board-level connector), and requires a suggested PSU of 1150 W. The RTX 4060 has a TDP of 115 W, is a dual-slot card, uses a single 12-pin power connector, and has a suggested PSU of 300 W. The MI300X uses a PCIe 5.0 x16 interface, while the RTX 4060 uses PCIe 4.0 x8. The MI300X has no dimensions recorded, while the RTX 4060 is 240 mm long, 111 mm high, and 40 mm wide.

The API support is a key separator. The MI300X has N/A for DirectX, OpenGL, and Vulkan, meaning it is not designed for those graphics APIs. The RTX 4060 supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4. The production status also differs: the MI300X has no recorded status, while the RTX 4060 is listed as end-of-life. The release dates are close, with the MI300X released on 2023-12-05 and the RTX 4060 on 2023-05-17. The MI300X’s predecessor is the Radeon Instinct, while the RTX 4060’s predecessor is the GeForce 30 series and its successor is the GeForce 50 series.