AMD Instinct MI300X vs AMD Radeon RX 7650 GRE Comparison

Head-to-Head Benchmarks

The recorded data contains one direct head-to-head comparison between the AMD Instinct MI300X and the AMD Radeon RX 7650 GRE, and the result is decisive. In the Geekbench OpenCL test, the Instinct MI300X scores 317,994 points, while the Radeon RX 7650 GRE scores 83,109 points. That represents a 282.6% advantage for the Instinct MI300X, meaning the accelerator delivers nearly four times the compute throughput of the consumer graphics card in this particular workload.

Context from the nearest rivals in the database reinforces how lopsided this matchup is. The Instinct MI300X sits at the 100th percentile among all GPUs, and its nearest competitors are enterprise and data center parts such as the NVIDIA B200 at 345,482 points, the NVIDIA H200 NVL at 334,891 points, and the NVIDIA L40S at 295,763 points. The Instinct MI300X trails the B200 by 8% and the H200 NVL by 5%, while leading the L40S by 7.5% and the RTX 6000 Ada Generation by 10.7%. These are the only rival comparisons recorded, and they place the MI300X squarely in the upper tier of accelerator-class hardware.

The Radeon RX 7650 GRE, by contrast, holds the 83rd percentile among all GPUs. Its nearest rivals in the database are all consumer or workstation cards with similar average scores: the NVIDIA GeForce RTX 4070 SUPER at 43,223 points (1.2% ahead), the NVIDIA Quadro M6000 24 GB at 43,262 points (1.2% ahead), the NVIDIA GeForce RTX 5050 Mobile at 43,268 points (1.3% ahead), and the NVIDIA Quadro M6000 at 43,301 points (1.3% ahead). The RX 7650 GRE trails each of these by a narrow margin, indicating that its performance profile is closely clustered with mid-range offerings rather than competing with any high-end parts.

What the head-to-head data shows is a complete absence of overlap between these two products. The 282.6% delta in Geekbench OpenCL is not a marginal difference; it is a gap that reflects fundamentally different design goals. The MI300X wins the only recorded benchmark, and the database shows zero wins for the RX 7650 GRE in any shared test. For any workload that resembles the Geekbench OpenCL compute pattern, the MI300X is in a different performance class entirely.

Architecture Differences

The two AMD products share a manufacturer but diverge completely in architecture, process technology, and design philosophy. The Instinct MI300X uses the Aqua Vanjaram chip built on CDNA 3.0 architecture, fabricated on a 5 nm process at TSMC. It packs 153,000 million transistors onto a 1017 mm² die, yielding a transistor density of 150.4 million per square millimeter. The Radeon RX 7650 GRE uses the Navi 33 chip based on RDNA 3.0 architecture, also fabricated by TSMC but on a 6 nm process. It contains 13,300 million transistors on a 204 mm² die, with a density of 65.2 million per square millimeter.

The scale difference is immense. The MI300X has more than 11 times the transistor count of the RX 7650 GRE and a die that is roughly five times larger. Shading unit counts tell a similar story: the MI300X has 19,456 shading units and 1,216 texture mapping units, while the RX 7650 GRE has 2,048 shading units and 128 TMUs. The MI300X reports zero ROPs and a pixel rate of 0 MPixel/s, which is consistent with its role as a compute accelerator without a display pipeline. The RX 7650 GRE has 64 ROPs and a pixel rate of 172.5 GPixel/s, along with 32 ray tracing cores.

Clock behavior also differs sharply. The MI300X has a base clock of 1000 MHz and a boost clock of 2100 MHz. The RX 7650 GRE runs at a base of 1720 MHz, a game clock of 2350 MHz, and a boost of 2695 MHz. Despite the lower clocks, the MI300X achieves far higher throughput due to its massive parallel resources: 81.72 TFLOPS FP32 and FP16 (1:1) versus 22.08 TFLOPS for the RX 7650 GRE in both precisions.

Memory architecture reinforces the divide. The MI300X carries 192 GB of HBM3 on an 8192-bit bus, delivering 5.32 TB/s of bandwidth. The RX 7650 GRE has 8 GB of GDDR6 on a 128-bit bus, providing 288.0 GB/s. That is a bandwidth ratio of roughly 18 to 1 in favor of the accelerator. The MI300X also uses a PCIe 5.0 x16 interface and an OAM module slot width with no power connectors, while the RX 7650 GRE uses PCIe 4.0 x8, a dual-slot design, and a single 8-pin power connector.

Feature support diverges as well. The RX 7650 GRE exposes DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4, along with display outputs of 1x HDMI 2.1a and 3x DisplayPort 2.1. The MI300X lists no display outputs and marks DirectX, OpenGL, and Vulkan as N/A. The RX 7650 GRE is marked as an active production part, while the MI300X has no production status recorded. Release dates are 2025-02-06 for the RX 7650 GRE and 2023-12-05 for the MI300X. The RX 7650 GRE has a recorded launch MSRP of 279 USD; the MI300X has none.

The Verdict

The data supports a straightforward conclusion: these products serve entirely different purposes and should not be considered competitors. The Instinct MI300X is a data center accelerator designed for massive parallel compute, as evidenced by its 192 GB HBM3 memory, 8192-bit bus, 5.32 TB/s bandwidth, 19,456 shading units, and 81.72 TFLOPS FP32 throughput. The Radeon RX 7650 GRE is a consumer graphics card with 8 GB GDDR6, 2,048 shading units, 22.08 TFLOPS, and full display and API support for gaming and general graphics workloads.

Benchmark data confirms the hierarchy. In Geekbench OpenCL, the MI300X leads by 282.6%, and its percentile rank of 100 places it above every other recorded GPU. The RX 7650 GRE at the 83rd percentile is competitive only with mid-range cards like the RTX 4070 SUPER and Quadro M6000 series. The MI300X also draws its nearest rivals exclusively from enterprise accelerators, while the RX 7650 GRE draws its nearest rivals from consumer and professional graphics cards. There is no overlap in competitive positioning.

For a user selecting a GPU strictly from the recorded data, the choice depends entirely on workload. Any task requiring the compute scale of the MI300X, such as large model inference or scientific computing, has no alternative in this comparison. Any task requiring graphics output, standard API support, or consumer software compatibility has no option in the MI300X, which lacks display outputs and API support entirely. The RX 7650 GRE is the only one of the two that can drive a monitor or run DirectX, OpenGL, or Vulkan applications.

The database shows one winner in the head-to-head benchmark, and that winner is the MI300X by a wide margin. But the absence of any shared feature set means the comparison is more about class distinction than performance ranking. The MI300X wins the compute test, while the RX 7650 GRE wins every category involving graphics functionality by virtue of being the only card with such functionality.

FAQ

Q: Which GPU has the higher Geekbench OpenCL score?

A: The AMD Instinct MI300X scores 317,994 points compared to 83,109 for the AMD Radeon RX 7650 GRE, a 282.6% difference.

Q: How does the Instinct MI300X compare to its nearest rivals?

A: The MI300X trails the NVIDIA B200 by 8% and the NVIDIA H200 NVL by 5%, while leading the NVIDIA L40S by 7.5% and the NVIDIA RTX 6000 Ada Generation by 10.7%.

Q: How does the Radeon RX 7650 GRE compare to its nearest rivals?

A: The RX 7650 GRE trails the NVIDIA GeForce RTX 4070 SUPER by 1.2%, the NVIDIA Quadro M6000 24 GB by 1.2%, the NVIDIA GeForce RTX 5050 Mobile by 1.3%, and the NVIDIA Quadro M6000 by 1.3%.

Q: Can the Instinct MI300X output video to a display?

A: No, the MI300X has no display outputs and lists DirectX, OpenGL, and Vulkan as N/A. The RX 7650 GRE has 1x HDMI 2.1a and 3x DisplayPort 2.1 outputs.

Q: What memory configurations do the two GPUs use?

A: The MI300X uses 192 GB of HBM3 on an 8192-bit bus with 5.32 TB/s bandwidth. The RX 7650 GRE uses 8 GB of GDDR6 on a 128-bit bus with 288.0 GB/s bandwidth.

Q: What are the release dates for these products?

A: The MI300X was released on 2023-12-05, and the RX 7650 GRE was released on 2025-02-06.

Where Each One Wins

The Instinct MI300X wins in every compute-oriented metric recorded. Its FP32 and FP16 throughput of 81.72 TFLOPS is 3.7 times that of the RX 7650 GRE. Its texture rate of 2,553.6 GTexel/s is 7.4 times the 345.0 GTexel/s of the RX 7650 GRE. Memory bandwidth of 5.32 TB/s is 18.5 times the 288.0 GB/s of the RX 7650 GRE. The Geekbench OpenCL score of 317,994 is 3.8 times the 83,109 of the RX 7650 GRE. The MI300X also sits at the 100th percentile versus the 83rd percentile for the RX 7650 GRE.

The Radeon RX 7650 GRE wins in every graphics and consumer-oriented category. It has 64 ROPs and a pixel rate of 172.5 GPixel/s, while the MI300X has zero ROPs and 0 MPixel/s. The RX 7650 GRE supports DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4, while the MI300X has N/A for all three. The RX 7650 GRE has display outputs and a dual-slot form factor with a single 8-pin power connector, while the MI300X is an OAM module with no outputs and no power connectors. The RX 7650 GRE also has higher clocks: a 1720 MHz base, 2350 MHz game, and 2695 MHz boost, compared to 1000 MHz base and 2100 MHz boost for the MI300X.

The RX 7650 GRE wins on power efficiency in the sense that its 170 W TDP is far lower than the 750 W TDP of the MI300X, and its suggested PSU of 450 W is much lower than the 1150 W suggested for the MI300X. The RX 7650 GRE also has a smaller physical footprint at 204 mm length and 115 mm height, while the MI300X has no recorded dimensions.

Specification Differences

The following specifications differ between the two products:

• Chip: Aqua Vanjaram for the MI300X, Navi 33 for the RX 7650 GRE
• Architecture: CDNA 3.0 for the MI300X, RDNA 3.0 for the RX 7650 GRE
• Process Node: 5 nm for the MI300X, 6 nm for the RX 7650 GRE
• Transistors: 153,000 million for the MI300X, 13,300 million for the RX 7650 GRE
• Die Size: 1017 mm² for the MI300X, 204 mm² for the RX 7650 GRE
• Transistor Density: 150.4M / mm² for the MI300X, 65.2M / mm² for the RX 7650 GRE
• Base Clock: 1000 MHz for the MI300X, 1720 MHz for the RX 7650 GRE
• Boost Clock: 2100 MHz for the MI300X, 2695 MHz for the RX 7650 GRE
• Game Clock: None for the MI300X, 2350 MHz for the RX 7650 GRE
• Memory Clock: 1300 MHz (5.2 Gbps effective) for the MI300X, 2250 MHz (18 Gbps effective) for the RX 7650 GRE
• Memory Size: 192 GB for the MI300X, 8 GB for the RX 7650 GRE
• Memory Type: HBM3 for the MI300X, GDDR6 for the RX 7650 GRE
• Memory Bus Width: 8192 bit for the MI300X, 128 bit for the RX 7650 GRE
• Memory Bandwidth: 5.32 TB/s for the MI300X, 288.0 GB/s for the RX 7650 GRE
• Shading Units: 19,456 for the MI300X, 2,048 for the RX 7650 GRE
• TMUs: 1,216 for the MI300X, 128 for the RX 7650 GRE
• ROPs: 0 for the MI300X, 64 for the RX 7650 GRE
• RT Cores: None for the MI300X, 32 for the RX 7650 GRE
• Pixel Rate: 0 MPixel/s for the MI300X, 172.5 GPixel/s for the RX 7650 GRE
• Texture Rate: 2,553.6 GTexel/s for the MI300X, 345.0 GTexel/s for the RX 7650 GRE
• FP32: 81.72 TFLOPS for the MI300X, 22.08 TFLOPS for the RX 7650 GRE
• FP16: 81.72 TFLOPS for the MI300X, 22.08 TFLOPS for the RX 7650 GRE
• TDP: 750 W for the MI300X, 170 W for the RX 7650 GRE
• Slot Width: OAM Module for the MI300X, Dual-slot for the RX 7650 GRE
• Power Connectors: None for the MI300X, 1x 8-pin for the RX 7650 GRE
• Suggested PSU: 1150 W for the MI300X, 450 W for the RX 7650 GRE
• Bus Interface: PCIe 5.0 x16 for the MI300X, PCIe 4.0 x8 for the RX 7650 GRE
• Display Outputs: No outputs for the MI300X, 1x HDMI 2.1a and 3x DisplayPort 2.1 for the RX 7650 GRE
• DirectX: N/A for the MI300X, 12 Ultimate (12_2) for the RX 7650 GRE
• OpenGL: N/A for the MI300X, 4.6 for the RX 7650 GRE
• Vulkan: N/A for the MI300X, 1.4 for the RX 7650 GRE
• Dimensions: None recorded for the MI300X, 204 mm length and 115 mm height for the RX 7650 GRE
• Production Status: None for the MI300X, Active for the RX 7650 GRE
• Release Date: 2023-12-05 for the MI300X, 2025-02-06 for the RX 7650 GRE
• Predecessor: Radeon Instinct for the MI300X, Navi II for the RX 7650 GRE
• Successor: None for the MI300X, Navi IV for the RX 7650 GRE
• Launch MSRP: None for the MI300X, 279 USD for the RX 7650 GRE