AMD Radeon RX 6750 GRE 12 GB vs NVIDIA RTX A6000 Comparison

Head-to-Head Benchmarks

The database contains one direct head-to-head comparison between the AMD Radeon RX 6750 GRE 12 GB and the NVIDIA RTX A6000, and it is a decisive victory for the NVIDIA card. In the Geekbench Vulkan test, the RTX A6000 scores 164,462, while the RX 6750 GRE manages 108,994. That works out to a 33.7% deficit for the AMD card, which is a substantial gap in raw API-level performance. For context, the RX 6750 GRE’s average benchmark score across all recorded tests is 55,698, while the RTX A6000 sits at 44,075. Interestingly, the AMD card actually holds a higher percentile rank among all GPUs (87th percentile versus 84th), despite losing this specific head-to-head matchup. This suggests the AMD card’s average performance is propped up by other tests where it does relatively better, whereas the A6000’s average is dragged down by its older DirectX 9 and DirectX 10 results, which are not representative of modern workloads.

Looking at the Vulkan result specifically, the RTX A6000’s lead of roughly one-third is consistent with its much larger compute footprint. The A6000 has 10,752 shading units compared to 2,560 on the RX 6750 GRE, and its FP32 throughput is 38.71 TFLOPS versus 13.21 TFLOPS. These are not close numbers, and the benchmark reflects that. The AMD card is not without merit, though: in the 3DMark Steel Nomad DX12 test, the RX 6750 GRE posts a score of 2,402, which is a respectable result for a mid-range RDNA 2 part. The A6000 does not have a recorded score for that test in the database, so direct comparison there is impossible. Similarly, the A6000 has PassMark scores (DirectX 10 at 155, DirectX 11 at 191, DirectX 12 at 87, DirectX 9 at 245, G2D at 913, G3D at 22,577, and GPU compute at 14,110), but the RX 6750 GRE has no corresponding entries, so those cannot be weighed against each other.

The nearest rivals for each card further illuminate their positions. The RX 6750 GRE is bracketed by the AMD Radeon 8060S (average score 55,757, a 0.1% gap), the NVIDIA GeForce RTX 5080 (56,083, a 0.7% gap), the AMD Radeon Pro W5700X (54,828, a 1.6% gap), and the NVIDIA GeForce RTX 4080 (54,247, a 2.7% gap). This places the RX 6750 GRE squarely in the upper-midrange tier, trading blows with flagship-class cards from both vendors. The RTX A6000, by contrast, sits near the NVIDIA GeForce RTX 4090 Mobile (43,667, a 0.9% gap), the RTX 4070 Ti (44,795, a 1.6% gap in the other direction), the Quadro M6000 (43,301, a 1.8% gap), and the RTX 5050 Mobile (43,268, a 1.9% gap). The A6000’s average is lower than the RX 6750 GRE’s, but its peak performance in Vulkan is far higher, indicating that the A6000 is a specialized tool rather than a general-purpose all-rounder.

FAQ

Q: Which card wins the direct head-to-head benchmark in the database?

A: The NVIDIA RTX A6000 wins the only shared test, Geekbench Vulkan, with a score of 164,462 versus 108,994 for the AMD Radeon RX 6750 GRE, a 33.7% advantage.

Q: How does the average benchmark score compare between the two cards?

A: The RX 6750 GRE has a higher average benchmark score of 55,698, while the RTX A6000 averages 44,075. The AMD card also ranks higher in percentile among all GPUs, at 87th versus 84th for the NVIDIA card.

Q: What is the closest rival to each card based on average score?

A: For the RX 6750 GRE, the closest rival is the AMD Radeon 8060S with an average score of 55,757, just 0.1% ahead. For the RTX A6000, the closest rival is the NVIDIA GeForce RTX 4090 Mobile at 43,667, which is 0.9% behind.

Q: Does the RTX A6000 have tensor cores?

A: Yes, the RTX A6000 features 336 tensor cores. The RX 6750 GRE does not list any tensor cores in the database.

Q: Which card has more memory and bandwidth?

A: The RTX A6000 has 48 GB of GDDR6 memory on a 384-bit bus, delivering 768.0 GB/s of bandwidth. The RX 6750 GRE has 12 GB of GDDR6 on a 192-bit bus, with 432.0 GB/s of bandwidth.

Q: What is the production status of each card?

A: The AMD Radeon RX 6750 GRE is listed as “Active,” while the NVIDIA RTX A6000 is marked as “End-of-life.”

The Verdict

The data paints a clear picture: the NVIDIA RTX A6000 is the performance king in raw compute, but the AMD Radeon RX 6750 GRE is the better-rounded card for typical gaming and consumer workloads. The A6000’s 33.7% lead in Vulkan is decisive, and its 38.71 TFLOPS of FP32 performance dwarfs the RX 6750 GRE’s 13.21 TFLOPS. If your workload is built around Vulkan compute, large memory buffers, or professional rendering, the A6000 is the obvious choice. It also has 48 GB of VRAM, which is four times the RX 6750 GRE’s 12 GB, and its 768.0 GB/s of bandwidth is nearly double the AMD card’s 432.0 GB/s. These are not incremental differences; they are category-defining ones.

On the other hand, the RX 6750 GRE holds a higher average benchmark score (55,698 versus 44,075) and a higher percentile rank (87th versus 84th). This indicates that across a broad set of tests, the AMD card is more consistent and better suited to diverse workloads. Its 3DMark Steel Nomad DX12 score of 2,402 shows it can handle modern DirectX 12 titles, and its smaller footprint (335 mm² die, 17,200 million transistors) makes it a more practical part for standard PC builds. The A6000, by contrast, is a workstation card with a 628 mm² die and 28,300 million transistors, built for sustained compute rather than gaming responsiveness.

For a builder assembling a gaming rig or a general-purpose desktop, the RX 6750 GRE is the safer bet. For a professional who needs maximum compute throughput and massive memory capacity, the RTX A6000 is the only option that fits. The launch MSRP of the RX 6750 GRE is 334 USD, while the RTX A6000 launched at 4,649 USD, but the price difference is not the deciding factor here; the architectural priorities are.

Specification Differences

The two cards diverge sharply on core specifications. The RX 6750 GRE uses a 7 nm process from TSMC, while the RTX A6000 uses an 8 nm process from Samsung. Transistor counts tell the story of scale: the A6000 packs 28,300 million transistors on a 628 mm² die, versus 17,200 million on a 335 mm² die for the RX 6750 GRE. Transistor density is slightly higher on the AMD card at 51.3M per mm², compared to 45.1M per mm² for the NVIDIA part, reflecting the newer process node.

Clock speeds favor AMD. The RX 6750 GRE has a base clock of 2321 MHz, a boost of 2581 MHz, and a game clock of 2439 MHz. The RTX A6000 runs at 1410 MHz base and 1800 MHz boost, with no game clock listed. Memory clocks also differ: the RX 6750 GRE runs at 2250 MHz (18 Gbps effective), while the A6000 runs at 2000 MHz (16 Gbps effective). Despite the lower memory clock, the A6000’s wider 384-bit bus gives it 768.0 GB/s of bandwidth, far exceeding the RX 6750 GRE’s 432.0 GB/s from its 192-bit bus.

The compute units are radically different. The RX 6750 GRE has 2,560 shading units, 160 TMUs, 64 ROPs, and 40 ray tracing cores. The RTX A6000 has 10,752 shading units, 336 TMUs, 112 ROPs, 84 ray tracing cores, and 336 tensor cores. Pixel and texture rates follow suit: the A6000 achieves 201.6 GPixel/s and 604.8 GTexel/s, while the RX 6750 GRE manages 165.2 GPixel/s and 413.0 GTexel/s. FP16 output is notable: the RX 6750 GRE delivers 26.43 TFLOPS at a 2:1 ratio, while the A6000 delivers 38.71 TFLOPS at a 1:1 ratio, meaning the NVIDIA card sustains full FP16 throughput without a penalty.

Power and physical specifications also differ. The RX 6750 GRE has a TDP of 250 W with a suggested PSU of 600 W, while the RTX A6000 has a TDP of 300 W and a suggested PSU of 700 W. Both are dual-slot cards, but the RX 6750 GRE uses a 1x 6-pin plus 1x 8-pin power connector setup, while the A6000 uses an 8-pin EPS connector. Display outputs are different as well: the RX 6750 GRE offers 1x HDMI 2.1 and 3x DisplayPort 1.4a, while the RTX A6000 provides 4x DisplayPort 1.4a with no HDMI. Both use PCIe 4.0 x16 interfaces.

Architecture Differences

The architectural gap is fundamental. The RX 6750 GRE is built on RDNA 2.0, AMD’s gaming-focused architecture, and belongs to the Navi II generation. The RTX A6000 is an Ampere architecture part from NVIDIA’s Workstation Ampere generation. The chip designs reflect their purposes: Navi 22 is a compact, power-efficient GPU optimized for high clock speeds and gaming workloads, while GA102 is a massive compute-oriented chip designed for professional rendering, AI inference, and scientific compute.

The most significant architectural divergence is the presence of tensor cores on the NVIDIA card. The RTX A6000 has 336 tensor cores, which are absent on the RX 6750 GRE. This gives the A6000 a dedicated path for AI and deep learning workloads that the AMD card cannot match. Ray tracing hardware is also stronger on the A6000, with 84 RT cores versus 40 on the RX 6750 GRE, though both cards support DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4.

Cache and memory hierarchy details are not fully listed, but the memory subsystems tell a clear story. The A6000’s 48 GB of VRAM is not just larger; it is designed for datasets that would exhaust the RX 6750 GRE’s 12 GB in minutes. The 384-bit bus and 768.0 GB/s bandwidth are workstation-class, while the RX 6750 GRE’s 192-bit bus and 432.0 GB/s are more typical of a gaming card. The FP16 ratio also highlights the difference: the RX 6750 GRE halves its FP16 rate (2:1), while the A6000 maintains a 1:1 ratio, making it far more efficient for half-precision compute tasks.

Process technology is another differentiator. TSMC’s 7 nm node used by AMD offers better transistor density (51.3M per mm²) than Samsung’s 8 nm node used by NVIDIA (45.1M per mm²). This explains why the RX 6750 GRE can hit higher clocks (2581 MHz boost versus 1800 MHz) while consuming less power (250 W versus 300 W). However, the A6000 compensates with sheer scale, packing more than 1.6 times the transistors and nearly double the die area.

Where Each One Wins

The RTX A6000 wins in every scenario that demands raw compute throughput. If the workload is Vulkan-based rendering, the A6000’s 33.7% lead is decisive. If the task involves large machine learning models or dataset processing, the 48 GB memory capacity and 336 tensor cores make it the only viable choice between these two. The A6000 also wins on bandwidth, with 768.0 GB/s versus 432.0 GB/s, which matters for texture-heavy professional applications. Its FP32 and FP16 performance (38.71 TFLOPS each) is nearly triple the RX 6750 GRE’s FP32 output, and the 1:1 FP16 ratio means no performance penalty for half-precision work. For sustained compute, the A6000’s 300 W TDP and 700 W suggested PSU indicate it is built for longer, more demanding sessions.

The RX 6750 GRE wins on overall versatility and efficiency. Its higher average benchmark score (55,698 versus 44,075) and percentile rank (87th versus 84th) show that it performs well across a wider range of tests, including modern DirectX 12 titles where it scores 2,402 in 3DMark Steel Nomad. The AMD card’s higher clock speeds (2321 MHz base, 2581 MHz boost) and lower power draw (250 W versus 300 W) make it a better fit for standard gaming PCs with typical power supplies. Its 12 GB of VRAM is sufficient for 1440p and 4K gaming, and its HDMI 2.1 output supports modern displays, something the A6000 lacks entirely. For a gamer or a mixed-use desktop builder, the RX 6750 GRE is the practical pick.

In short, the A6000 is a specialized compute weapon, and the RX 6750 GRE is a jack-of-all-trades. The database shows one clear head-to-head win for NVIDIA, but the broader averages favor AMD. Choose based on the workload, not the hype.