AMD Radeon RX 6750 GRE 12 GB vs NVIDIA GeForce RTX 5080 Comparison

The benchmark data presents a stark generational and performance-class divide. The NVIDIA GeForce RTX 5080 dominates the shared test suite, but the AMD Radeon RX 6750 GRE 12 GB holds a unique position in the aggregate rankings, making this comparison less about direct competition and more about contrasting performance tiers.

Head-to-Head Benchmarks

The two cards share only two benchmark results in the data, and in both, the NVIDIA GeForce RTX 5080 delivers a decisive victory. In the 3DMark Steel Nomad DX12 test, the RTX 5080 scores 8,637 points against the RX 6750 GRE's 2,402 points. This translates to a 259.6% delta, meaning the RTX 5080 is roughly 2.6 times faster in this demanding modern API workload. This is not a marginal gap; it is a categorical difference in rendering throughput.

The second shared test, Geekbench Vulkan, shows a similar but slightly less extreme margin. The RTX 5080 posts a score of 255,450, while the AMD card manages 108,994. The resulting 134.4% delta indicates the NVIDIA card is more than twice as fast in Vulkan compute and graphics workloads. Both results point to the same conclusion: in any scenario where both cards are stressed equally, the RTX 5080’s architecture delivers overwhelming performance advantages.

However, the aggregate picture is more nuanced. The RTX 5080 holds an average benchmark score of 56,083 across its ten recorded tests. The RX 6750 GRE, with only two recorded tests, still achieves an average of 55,698. This places the AMD card remarkably close in the overall database standings, with the RTX 5080 leading by only 0.7% in average score. The data warns against assuming the head-to-head results tell the whole story; the RX 6750 GRE’s strong showing in other unshared benchmarks (like PassMark G3D and Geekbench OpenCL for the RTX 5080) suggests its aggregate performance is competitive with far newer hardware in specific legacy or compute scenarios.

Where Each One Wins

The RTX 5080 wins every directly comparable benchmark, making its case straightforward. It is the clear choice for any workload that leverages modern DX12 or Vulkan APIs, where its raw shader throughput and dedicated hardware accelerate performance. The 259.6% lead in 3DMark Steel Nomad is particularly telling for next-generation gaming and high-fidelity rendering, as this test is designed to scale with the latest graphics features. For users prioritizing maximum frame rates in current and upcoming titles, the data exclusively favors the NVIDIA card.

The RX 6750 GRE’s wins are not in direct comparison but in its aggregate profile. Despite having only two benchmarks recorded, its average score of 55,698 is within 0.7% of the RTX 5080’s average of 56,083. This implies that in the broader spectrum of benchmarks—such as the PassMark suite that the RTX 5080 participates in—the AMD card would likely hold its own or even excel in specific tests like DirectX 10 or DirectX 9, where its older architecture can still be highly efficient. The RX 6750 GRE also matches the RTX 5080 in percentile rank, with both cards sitting at the 87th percentile among all GPUs. This suggests that for a user with a mixed workload of older and newer applications, the RX 6750 GRE offers a level of overall capability that rivals the much newer flagship, even if it loses in pure modern-API performance.

Architecture Differences

The architectural gap between these two cards is immense, reflecting their different release eras and design goals. The RTX 5080 is built on the Blackwell 2.0 architecture using TSMC's 5 nm process node, packing 45,600 million transistors into a 378 mm² die. This results in a transistor density of 120.6 million per square millimeter. In contrast, the RX 6750 GRE uses the RDNA 2.0 architecture on TSMC's older 7 nm node, with 17,200 million transistors on a 335 mm² die, yielding a density of just 51.3 million per square millimeter. The RTX 5080’s newer node allows for significantly more complex hardware in a similar physical footprint.

The NVIDIA card features 10,752 shading units, 336 texture mapping units, and 112 ROPs, alongside 84 dedicated RT cores and 336 tensor cores. The AMD card is far more modest, with 2,560 shading units, 160 TMUs, and 64 ROPs, plus 40 RT cores and no tensor core equivalent listed. This hardware disparity explains the massive performance delta in modern workloads. The RTX 5080 also supports FP16 at a 1:1 ratio with FP32 (56.28 TFLOPS each), while the RX 6750 GRE runs FP16 at a 2:1 ratio, offering 26.43 TFLOPS FP16 versus 13.21 TFLOPS FP32. The presence of tensor cores on the RTX 5080 and their absence on the AMD card is a critical feature gap for AI-accelerated tasks.

Specification Differences

The specifications that differ between the two cards highlight their distinct positioning. The RTX 5080 uses 16 GB of GDDR7 memory on a 256-bit bus, delivering 960.0 GB/s of bandwidth. The RX 6750 GRE uses 12 GB of GDDR6 on a 192-bit bus, which provides 432.0 GB/s. This 528 GB/s difference in bandwidth is a major factor in 4K gaming and high-resolution texture streaming. Clock speeds are surprisingly close: the RTX 5080 has a base clock of 2295 MHz and a boost of 2617 MHz, while the AMD card has a higher base of 2321 MHz but a slightly lower boost of 2581 MHz. The AMD card also lists a game clock of 2439 MHz, a figure the NVIDIA card does not provide.

Power and connectivity requirements also diverge sharply. The RTX 5080 has a TDP of 360 W and requires a 750 W power supply with a single 16-pin connector. The RX 6750 GRE is more power-efficient on paper, with a 250 W TDP and a 600 W recommended PSU, using a 6-pin plus 8-pin configuration. The bus interface differs as well: the RTX 5080 uses PCIe 5.0 x16, while the RX 6750 GRE is limited to PCIe 4.0 x16. Display outputs are similar in count, but the RTX 5080 offers newer standards: one HDMI 2.1b and three DisplayPort 2.1b, versus the AMD card's one HDMI 2.1 and three DisplayPort 1.4a. Physical dimensions also differ, with the RTX 5080 being longer at 304 mm compared to the RX 6750 GRE's 267 mm, though both are dual-slot cards with a 40 mm width.

FAQ

Q: Which card has a higher average benchmark score?

A: The NVIDIA GeForce RTX 5080 has a slightly higher average benchmark score of 56,083, but the AMD Radeon RX 6750 GRE 12 GB is extremely close at 55,698, a difference of only 0.7%.

Q: How much faster is the RTX 5080 in 3DMark Steel Nomad?

A: The RTX 5080 scores 8,637 points versus 2,402 points for the RX 6750 GRE, which represents a 259.6% performance advantage for the NVIDIA card.

Q: What are the memory specifications for each card?

A: The RTX 5080 has 16 GB of GDDR7 memory on a 256-bit bus with 960.0 GB/s bandwidth. The RX 6750 GRE has 12 GB of GDDR6 memory on a 192-bit bus with 432.0 GB/s bandwidth.

Q: Do both cards support the same level of DirectX?

A: Yes, both cards support DirectX 12 Ultimate (12_2), as well as OpenGL 4.6 and Vulkan 1.4.

Q: Which card has a higher transistor density?

A: The RTX 5080 has a much higher transistor density at 120.6 million per square millimeter, compared to the RX 6750 GRE's 51.3 million per square millimeter.

Q: What are the power supply requirements for each card?

A: The RTX 5080 has a 360 W TDP and recommends a 750 W power supply, while the RX 6750 GRE has a 250 W TDP and recommends a 600 W power supply.

The Verdict

The data is unambiguous for direct performance: the NVIDIA GeForce RTX 5080 is the superior card for any modern, demanding workload. With a 259.6% lead in 3DMark Steel Nomad and a 134.4% lead in Geekbench Vulkan, it offers more than double the performance of the RX 6750 GRE in the shared tests. Its 16 GB of GDDR7 memory with 960.0 GB/s bandwidth, coupled with 10,752 shading units and 84 RT cores, makes it the definitive choice for high-end gaming, ray tracing, and AI-accelerated applications. The RTX 5080 also carries a higher launch MSRP of 999 USD, but performance data justifies the premium for users who need maximum throughput.

The AMD Radeon RX 6750 GRE 12 GB, with a launch MSRP of 334 USD, is not a direct competitor in raw speed, but its aggregate benchmark average of 55,698 places it in the same percentile (87th) as the RTX 5080. This suggests it is a highly capable card for a broader range of software, particularly older APIs where its RDNA 2.0 architecture remains efficient. Its lower TDP of 250 W and smaller physical length of 267 mm make it an easier fit for compact builds or systems with less robust power supplies. Users who prioritize a balance of legacy application support, lower power draw, and a significantly lower price point will find the RX 6750 GRE a rational choice, despite its clear disadvantage in modern benchmark tests. The verdict is simple: choose the RTX 5080 for uncompromising performance today; choose the RX 6750 GRE for a more balanced overall profile at a fraction of the cost.