AMD Radeon RX 6750 GRE 12 GB vs NVIDIA GeForce RTX 4080 Comparison

# The Verdict

The data presents a stark hierarchy between these two GPUs, with the NVIDIA GeForce RTX 4080 winning both head-to-head benchmarks decisively. In 3DMark Steel Nomad DX12, the RTX 4080 scores 6567 versus the RX 6750 GRE's 2402, a delta of -63.4% for the AMD card. The Geekbench Vulkan result tells a similar story: 263779 for NVIDIA against 108994 for AMD, a -58.7% gap. The RTX 4080 takes both wins in the head-to-head suite, leaving the RX 6750 GRE with zero victories.

Yet the average benchmark scores complicate the picture. The RX 6750 GRE posts an average score of 55698, actually higher than the RTX 4080's 54247. This places the AMD card 2.7% ahead of its rival in the aggregate, and it sits at the 87th percentile of all GPUs versus the RTX 4080's 86th. The nearest rival data confirms the oddity: the RX 6750 GRE is listed as 2.7% ahead of the RTX 4080 in average score, while the RTX 4080 is listed as -2.6% behind the AMD card. This suggests the two benchmarks captured in the head-to-head may not represent the full performance envelope.

Who should pick which? For users prioritizing raw rasterization in modern DirectX 12 titles as measured by 3DMark Steel Nomad, the RTX 4080 is the clear choice—it delivers 2.7 times the score of the AMD card. For Vulkan workloads, the NVIDIA card again dominates with more than double the score. However, if the average benchmark score across the entire database is the metric that matters, the RX 6750 GRE actually edges ahead, suggesting it may hold its own in a broader range of legacy or compute-oriented tests not captured in the head-to-head. The RTX 4080 is marked end-of-life, while the RX 6750 GRE remains active in production. The RTX 4080's launch MSRP is 1,199 USD; the RX 6750 GRE's launch MSRP is 334 USD.

# Architecture Differences

The two cards come from fundamentally different design philosophies. The RX 6750 GRE uses the Navi 22 chip built on RDNA 2.0 architecture, fabricated on TSMC's 7 nm process. It packs 17,200 million transistors into a 335 mm² die, yielding a transistor density of 51.3 million per square millimeter. The RTX 4080, by contrast, uses the AD103 chip with Ada Lovelace architecture on a 5 nm process, also from TSMC. It holds 45,900 million transistors on a 379 mm² die, for a density of 121.1 million per square millimeter—more than double the AMD card's density.

The compute resources differ by a wide margin. The RX 6750 GRE features 2560 shading units, 160 texture mapping units, and 64 ROPs. The RTX 4080 has 9728 shading units, 304 TMUs, and 112 ROPs. For ray tracing, the AMD card has 40 RT cores, while NVIDIA brings 76. The RTX 4080 also includes 304 tensor cores, a feature the RX 6750 GRE lacks entirely. This absence of dedicated tensor hardware suggests the NVIDIA card has a distinct advantage in any AI-accelerated workloads, though the FACT PACK does not include specific AI benchmark scores.

Memory configurations also diverge. The RX 6750 GRE uses 12 GB of GDDR6 on a 192-bit bus, delivering 432.0 GB/s of bandwidth. The RTX 4080 uses 16 GB of GDDR6X on a 256-bit bus, for 716.8 GB/s. The clock speeds tell an interesting story: the AMD base clock is 2321 MHz with a boost of 2581 MHz, while NVIDIA's base is 2205 MHz and boost is 2505 MHz. Despite lower raw clocks, the NVIDIA card achieves far higher throughput due to its massive compute unit advantage.

# Where Each One Wins

The head-to-head data shows the RTX 4080 winning both benchmark categories—3DMark Steel Nomad DX12 and Geekbench Vulkan. In 3DMark's modern DirectX 12 test, the NVIDIA card scores 6567 versus 2402, a 63.4% advantage. This suggests the RTX 4080 is the stronger choice for contemporary DX12 gaming workloads that stress geometry, shading, and memory bandwidth. The Vulkan result (263779 vs 108994, a 58.7% gap) reinforces NVIDIA's dominance in cross-platform graphics APIs.

The RX 6750 GRE's only edge emerges from the aggregate benchmark data. With an average benchmark score of 55698, it sits 2.7% above the RTX 4080's 54247. This could indicate that in older DirectX tests (PassMark's DirectX 9, 10, 11, or 12 variants, for instance), the AMD card performs relatively better, even though those specific scores are not listed for the RX 6750 GRE in the FACT PACK. The RTX 4080's PassMark scores are available: DirectX 9 at 370, DirectX 10 at 204, DirectX 11 at 314, DirectX 12 at 132, G2D at 1239, G3D at 34457, and GPU compute at 20671. No equivalent data exists for the AMD card, so the source of its higher average remains unquantified.

For users prioritizing power efficiency and physical footprint, the RX 6750 GRE wins on paper. It has a TDP of 250 W versus 320 W for the RTX 4080, and it fits in a dual-slot form factor versus triple-slot for NVIDIA. The AMD card is also shorter at 267 mm versus 310 mm, and narrower at 110 mm height versus 140 mm. The RX 6750 GRE draws power from a 1x 6-pin plus 1x 8-pin connector, while the RTX 4080 requires a single 16-pin connector. The suggested PSU is 600 W for AMD and 700 W for NVIDIA.

# FAQ

Q: Which GPU has the higher average benchmark score?

A: The AMD Radeon RX 6750 GRE 12 GB has an average benchmark score of 55698, which is 2.7% higher than the NVIDIA GeForce RTX 4080's 54247.

Q: How large is the performance gap in 3DMark Steel Nomad DX12?

A: The RTX 4080 scores 6567 compared to the RX 6750 GRE's 2402, meaning the NVIDIA card leads by 63.4% in this test.

Q: Does the RX 6750 GRE have tensor cores?

A: No. The FACT PACK lists tensor cores as null for the RX 6750 GRE, while the RTX 4080 has 304 tensor cores.

Q: What are the memory specifications for each card?

A: The RX 6750 GRE has 12 GB of GDDR6 on a 192-bit bus with 432.0 GB/s bandwidth. The RTX 4080 has 16 GB of GDDR6X on a 256-bit bus with 716.8 GB/s bandwidth.

Q: Which card has a higher transistor density?

A: The RTX 4080 has a transistor density of 121.1 million per square millimeter, more than double the RX 6750 GRE's 51.3 million per square millimeter.

Q: Is the RTX 4080 still in production?

A: No, the RTX 4080 is marked as end-of-life, while the RX 6750 GRE has an active production status.

# Head-to-Head Benchmarks

The head-to-head suite contains only two tests, and the RTX 4080 dominates both. In 3DMark Steel Nomad DX12, the NVIDIA card scores 6567 against the AMD card's 2402, a delta of -63.4% from the RX 6750 GRE's perspective. This is the larger of the two gaps and suggests a fundamental throughput advantage for the RTX 4080 in modern DirectX 12 rendering. The RTX 4080's 48.74 TFLOPS of FP32 performance versus the RX 6750 GRE's 13.21 TFLOPS provides context: NVIDIA has 3.7 times the raw floating-point throughput, which translates directly to this benchmark's outcome.

The Geekbench Vulkan test shows a similar pattern but with a slightly smaller gap. The RTX 4080 scores 263779, while the RX 6750 GRE scores 108994, a -58.7% delta. This test likely exercises compute and memory subsystems more broadly. The NVIDIA card's 716.8 GB/s memory bandwidth versus 432.0 GB/s for AMD, combined with its 304 TMUs versus 160, helps explain the advantage. Interestingly, the RTX 4080's FP16 performance is rated at 48.74 TFLOPS (1:1 ratio), while the RX 6750 GRE achieves 26.43 TFLOPS FP16 (2:1 ratio). This 1:1 versus 2:1 ratio difference means the NVIDIA card maintains full FP32 throughput even in FP16 workloads, whereas AMD halves its rate.

The RTX 4080's pixel rate of 280.6 GPixel/s and texture rate of 761.5 GTexel/s dwarf the RX 6750 GRE's 165.2 GPixel/s and 413.0 GTexel/s. These fill rate advantages likely contribute to the NVIDIA card's wins in both tests. The wins are not marginal—they are decisive. Yet the average benchmark score reversal (where AMD leads by 2.7%) raises questions about whether these two tests capture the full picture. The RTX 4080's PassMark G3D score of 34457 and GPU compute score of 20671 are strong, but without equivalent RX 6750 GRE numbers, the aggregate comparison remains incomplete.

# Specification Differences

The two cards differ across nearly every measurable specification. The process node differs: 7 nm for AMD versus 5 nm for NVIDIA. Transistor counts are 17,200 million versus 45,900 million, with die sizes of 335 mm² and 379 mm² respectively. The RX 6750 GRE has 2560 shading units, 160 TMUs, and 64 ROPs; the RTX 4080 has 9728 shading units, 304 TMUs, and 112 ROPs. Ray tracing cores number 40 for AMD and 76 for NVIDIA. Tensor cores are absent on the AMD card but present at 304 on the NVIDIA card.

Clock speeds: AMD's base is 2321 MHz with a boost of 2581 MHz and a game clock of 2439 MHz. NVIDIA's base is 2205 MHz with a boost of 2505 MHz and no listed game clock. Memory clocks are 2250 MHz (18 Gbps effective) for AMD and 1400 MHz (22.4 Gbps effective) for NVIDIA. Memory capacity is 12 GB GDDR6 versus 16 GB GDDR6X, with bus widths of 192-bit versus 256-bit, yielding bandwidth of 432.0 GB/s versus 716.8 GB/s.

Compute throughput: FP32 is 13.21 TFLOPS for AMD versus 48.74 TFLOPS for NVIDIA. FP16 is 26.43 TFLOPS (2:1) for AMD versus 48.74 TFLOPS (1:1) for NVIDIA. Pixel rates are 165.2 GPixel/s versus 280.6 GPixel/s, and texture rates are 413.0 GTexel/s versus 761.5 GTexel/s. TDP is 250 W versus 320 W. Slot width is dual-slot versus triple-slot. Power connectors are 1x 6-pin + 1x 8-pin versus 1x 16-pin. Suggested PSU is 600 W versus 700 W. Dimensions: 267 mm length, 110 mm height, 40 mm width for AMD; 310 mm length, 140 mm height, 61 mm width for NVIDIA. Both use PCIe 4.0 x16 and have identical display outputs (1x HDMI 2.1, 3x DisplayPort 1.4a) and API support (DirectX 12 Ultimate, OpenGL 4.6, Vulkan 1.4). Release dates differ: 2023-10-16 for AMD versus 2022-09-19 for NVIDIA. Production status is Active versus End-of-life. The launch MSRP is 334 USD for AMD and 1,199 USD for NVIDIA.