AMD Radeon RX 5600 OEM vs NVIDIA Quadro M6000 24 GB Comparison

The Verdict - who should pick which, strictly from the data

The benchmark database places the AMD Radeon RX 5600 OEM and the NVIDIA Quadro M6000 24 GB in different performance tiers. The AMD part scores an average of 58,085 across recorded tests, which lands it in the 87th percentile of all GPUs in the database. The NVIDIA part averages 43,262, sitting in the 83rd percentile. The AMD card wins both recorded head-to-head tests, and the verdict from the data is clear: for raw compute throughput, the Radeon RX 5600 OEM is the stronger pick. The Quadro M6000 24 GB counters with a very large memory pool and professional feature set, but in every direct comparison where both parts ran the same workload, the AMD part came out ahead. The delta is substantial: 55.7% in the OpenCL test and 15.8% in the Vulkan test. The Quadro does have the advantage in memory capacity, 24 GB versus 6 GB, and in raw shading resources, but the measured compute results do not favor it. The data does not support choosing the NVIDIA card for performance, only for workloads that require its unique memory capacity or its professional display outputs.

Architecture Differences

The two cards come from different architectural families. The AMD Radeon RX 5600 OEM is built on the Navi 10 chip, using the RDNA 1.0 architecture, and it is manufactured on a 7 nm process at TSMC. The die contains 10,300 million transistors on a 251 mm² slice, which works out to 41.0 million transistors per mm². The NVIDIA Quadro M6000 24 GB is a different kind of part: it uses the GM200 chip with the Maxwell 2.0 architecture, built on a 28 nm process at TSMC. That die is much larger at 601 mm², holding 8,000 million transistors, for a density of 13.3 million per mm². The process advantage shows in the numbers: the AMD part packs more than twice the transistor density on a smaller die.

The clock behavior also differs. The AMD card runs a base clock of 1130 MHz with a boost of 1560 MHz and a game clock of 1375 MHz. Memory runs at 1500 MHz, which with a 192-bit bus and GDDR6 memory gives 288.0 GB/s of bandwidth. The NVIDIA card has a lower base of 988 MHz and a boost of 1114 MHz, with memory at 1653 MHz. Its memory is GDDR5 on a 384-bit bus with 24 GB capacity, delivering 317.4 GB/s. The AMD has the higher core clocks, while the NVIDIA has the higher memory clock and the wider bus.

The compute configuration shows the theme. The AMD card has 2048 shading units, 128 texture mapping units, and 64 ROPs. It lacks dedicated RT cores and tensor cores, and its pixel rate is 99.84 GPixel/s with a texture rate of 199.7 GTexel/s. FP32 is rated at 6.390 TFLOPS, and FP16 at 12.78 TFLOPS using the 2:1 ratio. The NVIDIA card has more shading units at 3072, 192 TMUs, and 96 ROPs. It has no RT or tensor cores either. Its pixel rate is 106.9 GPixel/s and texture rate is 213.9 GTexel/s. FP32 is rated at 6.844 TFLOPS, and the FP16 field is not listed.

The board power and power delivery differ. The AMD card has a TDP of 125 W and uses a single 8-pin connector, with a 300 W PSU suggested. The NVIDIA board has a 250 W TDP, also one 8-pin connector, and a 600 W PSU suggested. The AMD uses a PCIe 4.0 x16 interface; the NVIDIA uses PCIe 3.0 x16. Display outputs also differ: AMD lists 1x HDMI 2.0b and 3x DisplayPort 1.4a, while NVIDIA lists 1x DVI and 4x DisplayPort 1.2.

The production status is important. The AMD card is listed as end-of-life, released on January 20, 2020, with a predecessor named Vega and a successor named Navi II. The NVIDIA Quadro M6000 24 GB is also end-of-life, released March 4, 2016, with the Quadro Kepler as predecessor and Quadro Pascal as successor. The NVIDIA part has a launch MSRP of 4,999 USD listed in the database. The AMD part does not list a launch MSRP.

Head-to-Head Benchmarks

The database has two head-to-head results, both favoring the AMD card. The first is the Geekbench OpenCL run. Here the AMD Radeon RX 5600 OEM scores 62,427 points. The NVIDIA Quadro M6000 24 GB scores 40,098. The AMD part is 55.7% faster. The second test is the Geekbench Vulkan test. The AMD card scores 53,743, and the NVIDIA scores 46,425. This result is 15.8% in favor of the AMD card.

The OpenCL result is the largest margin of the two. A 55.7% lead in a compute-heavy test is substantial. It reflects the AMD card's higher base and boost clocks, its RDNA 1.0 design, and the fact that the NVIDIA part is based on the older Maxwell 2.0 architecture. The Vulkan delta is smaller, 15.8%, but still a clear AMD win. The data shows a consistent pattern: the RX 5600 OEM is the faster card in these tests, and the gap is not small.

The average benchmark score of the AMD card is 58,085, which is 34.3% higher than the NVIDIA average of 43,262. The 87th percentile vs. 83rd percentile also supports the same direction. In the aggregate, the measured compute performance belongs to the AMD Radeon RX 5600 OEM.

FAQ

Q: How does the AMD Radeon RX 5600 OEM compare to the NVIDIA Quadro M6000 24 GB in raw compute?

The average benchmark score of the AMD part (58,085) is 34.3% higher than the NVIDIA card's average (43,262). In the OpenCL test, the AMD leads by 55.7%, and in Vulkan it leads by 15.8%.

Q: Which card has more memory?

The NVIDIA Quadro M6000 24 GB has 24 GB of GDDR5 memory on a 384-bit bus. The AMD Radeon RX 5600 OEM has 6 GB of GDDR6 memory on a 192-bit bus.

Q: What are the architecture differences?

AMD uses Navi 10 with RDNA 1.0 on a 7 nm TSMC process. NVIDIA uses GM200 with Maxwell 2.0 on a 28 nm TSMC process. The AMD die is smaller (251 mm² vs 601 mm²) but holds more transistors (10,300 million vs 8,000 million).

Q: Which card has the higher core clock?

The AMD Radeon RX 5600 OEM has a base clock of 1130 MHz and a boost of 1560 MHz. The NVIDIA Quadro M6000 24 GB has a base clock of 988 MHz and a boost of 1114 MHz.

Q: Are there any API differences?

A: The AMD card supports DirectX 12 (12_1), OpenGL 4.6, and Vulkan 1.4. The NVIDIA card supports DirectX 12 (12_1), OpenGL 4.6, and Vulkan 1.4.

Where Each One Wins

The AMD Radeon RX 5600 OEM wins in the compute benchmarks. It is ahead in both recorded head-to-head tests, and its average benchmark percentile is higher (87th vs 83rd). The NVIDIA Quadro M6000 24 GB wins in memory capacity, offering 24 GB versus 6 GB, and it has more shading units (3072 vs 2048), more texture mapping units (192 vs 128), and more ROPs (96 vs 64). The NVIDIA card also has a higher memory clock (1653 MHz vs 1500 MHz) and a wider memory bus (384 bit vs 192 bit), giving it a much higher bandwidth (317.4 GB/s vs 288.0 GB/s). The AMD card has higher core clocks and a smaller process node, and it is the one with the display outputs of HDMI 2.0b and three DisplayPort 1.4a; the NVIDIA has one DVI and four DisplayPort 1.2 outputs. The AMD is the card to choose if the workload is compute-bound and the NVIDIA is the one for memory-heavy workloads, as the data shows.