AMD Radeon RX 5600 OEM vs NVIDIA Quadro GP100 Comparison

The NVIDIA Quadro GP100 and the AMD Radeon RX 5600 OEM sit on opposite ends of the workstation and consumer spectrum, separated by architecture, memory design, and intended workload. The database records a single head-to-head OpenCL benchmark, but the full specification sheets reveal much deeper divides. This analysis walks through the recorded data to show where each card excels, where it does not, and who should choose which.

FAQ

Q: What is the primary benchmark score for each GPU in the database?

A: The NVIDIA Quadro GP100 records a Geekbench OpenCL score of 87445, while the AMD Radeon RX 5600 OEM scores 62427 in the same test. The RX 5600 OEM also has a Geekbench Vulkan score of 53743, which the GP100 lacks in the recorded data.

Q: How do the two cards compare in overall percentile ranking?

A: The Quadro GP100 sits at the 93rd percentile among all GPUs, while the RX 5600 OEM sits at the 87th percentile. This places the GP100 in a higher overall performance tier, though the RX 5600 OEM still ranks above the majority of recorded cards.

Q: What are the nearest rivals to each card according to the database?

A: For the Quadro GP100, the closest competitors are the AMD Radeon PRO W7600 (87108, 0.4% slower), the NVIDIA CMP 40HX (85637, 2.1% slower), the NVIDIA RTX A4500 Mobile (91134, 4% faster), and the NVIDIA RTX A4500 (91671, 4.6% faster). For the RX 5600 OEM, the nearest rivals are the Intel Arc A570M (58239, 0.3% faster), the AMD Radeon RX 6950 XT (58392, 0.5% faster), the Intel Arc A580 (57756, 0.6% slower), and the NVIDIA P102-100 (58528, 0.8% faster).

Q: Which GPU has the larger memory capacity and wider bus?

A: The Quadro GP100 has 16 GB of HBM2 memory on a 4096-bit bus, yielding 732.2 GB/s of bandwidth. The RX 5600 OEM has 6 GB of GDDR6 memory on a 192-bit bus, delivering 288.0 GB/s.

Q: What are the process nodes for each chip?

A: The Quadro GP100 uses a 16 nm process from TSMC, while the RX 5600 OEM uses a 7 nm process, also from TSMC. The smaller node gives the RX 5600 OEM a higher transistor density of 41.0M per mm² versus 25.1M per mm² for the GP100.

Q: Do both cards support the same API versions?

A: Both support DirectX 12 (12_1) and OpenGL 4.6. They differ in Vulkan support: the GP100 supports Vulkan 1.3, while the RX 5600 OEM supports Vulkan 1.4.

Where Each One Wins

The Quadro GP100 wins the only recorded head-to-head test, the Geekbench OpenCL benchmark, with a score of 87445 against 62427 for the RX 5600 OEM. That is a 40.1% advantage, a decisive margin in raw compute throughput. The GP100’s shading unit count of 3584 versus 2048, its 224 texture units versus 128, and its 96 ROPs versus 64 all point to a card designed for heavy parallel workloads.

The RX 5600 OEM, however, wins in efficiency and generational technology. Its 7 nm process node allows a 125 W TDP versus 235 W for the GP100, despite a higher boost clock of 1560 MHz versus 1443 MHz. The RX 5600 OEM also supports PCIe 4.0 x16, while the GP100 is limited to PCIe 3.0 x16. For tasks that favor Vulkan, the RX 5600 OEM has a recorded Vulkan score of 53743, which the GP100 cannot match in the database because no Vulkan test exists for it.

The memory bandwidth story favors the GP100 overwhelmingly: 732.2 GB/s versus 288.0 GB/s. For data-intensive workloads like large dataset processing or multi-tasking across huge textures, the GP100’s HBM2 design is the clear winner. But for single-GPU gaming or lighter tasks, the RX 5600 OEM’s smaller memory footprint is sufficient, and its lower power draw makes it easier to integrate into smaller systems.

Architecture Differences

The Quadro GP100 is built on the Pascal architecture, using the GP100 chip. It is fabricated on a 16 nm process at TSMC, with 15,300 million transistors on a 610 mm² die. This large die houses 3584 shading units, 224 texture mapping units, and 96 ROPs. Memory is HBM2 across a 4096-bit bus, delivering 732.2 GB/s. The card supports DirectX 12 (12_1), OpenGL 4.6, and Vulkan 1.3, and its FP32 throughput is 10.34 TFLOPS, with FP16 at 20.69 TFLOPS (2:1).

The RX 5600 OEM uses the RDNA 1.0 architecture, built on the Navi 10 chip. It is fabricated on a 7 nm process, also at TSMC, with 10,300 million transistors on a 251 mm² die. This smaller die packs 2048 shading units, 128 TMUs, and 64 ROPs. Memory is GDDR6 across a 192-bit bus, yielding 288.0 GB/s. The RX 5600 OEM supports DirectX 12 (12_1), OpenGL 4.6, and Vulkan 1.4, with FP32 of 6.390 TFLOPS and FP16 of 12.78 TFLOPS (2:1).

The architectural split is clear: Pascal is a compute-oriented design with massive memory bandwidth and raw FP32 muscle, while RDNA 1.0 is a modern, denser architecture that trades raw throughput for lower power and newer API support. The transistor density difference, 25.1M per mm² versus 41.0M per mm², highlights how far 7 nm had come by 2020.

Specification Differences

The two cards differ in nearly every measurable field. The GP100 has a base clock of 1304 MHz and a boost of 1443 MHz, while the RX 5600 OEM has a base of 1130 MHz, a game clock of 1375 MHz, and a boost of 1560 MHz. Memory clocks differ: the GP100 runs at 715 MHz with 1430 Mbps effective, while the RX 5600 OEM runs at 1500 MHz with 12 Gbps effective.

Memory capacity is 16 GB versus 6 GB, with bus widths of 4096 bits versus 192 bits. Bandwidth is 732.2 GB/s versus 288.0 GB/s. Shading units are 3584 versus 2048, TMUs are 224 versus 128, and ROPs are 96 versus 64. Pixel rates are 138.5 GPixel/s versus 99.84 GPixel/s, and texture rates are 323.2 GTexel/s versus 199.7 GTexel/s.

TDP is 235 W versus 125 W, with the GP100 requiring a 550 W suggested PSU and the RX 5600 OEM needing only 300 W. Both are dual-slot cards with a single 8-pin power connector. The GP100 is 267 mm long and 111 mm tall, while the RX 5600 OEM has no recorded dimensions. Display outputs differ: the GP100 has 1x DVI and 4x DisplayPort 1.4a, while the RX 5600 OEM has 1x HDMI 2.0b and 3x DisplayPort 1.4a. The bus interface is PCIe 3.0 x16 for the GP100 and PCIe 4.0 x16 for the RX 5600 OEM.

Head-to-Head Benchmarks

The only recorded head-to-head test is Geekbench OpenCL. The Quadro GP100 scores 87445, and the RX 5600 OEM scores 62427. The delta is 40.1%, meaning the GP100 outperforms the RX 5600 OEM by over a third in this compute-heavy workload. This is the single largest margin in the comparison, and it aligns with the GP100’s hardware advantages: 3584 shading units versus 2048, and 732.2 GB/s memory bandwidth versus 288.0 GB/s.

For the RX 5600 OEM, the Vulkan score of 53743 is the only other benchmark in the database. While the GP100 has no Vulkan score recorded, the RX 5600 OEM’s Vulkan result can be compared to its own OpenCL score. The Vulkan score is 13.9% lower than its OpenCL score of 62427, suggesting the card’s OpenCL performance is stronger in this specific test.

The nearest rival data shows how each card sits in its own tier. The GP100’s closest rival, the Radeon PRO W7600, is only 0.4% slower, making the GP100’s lead over the RX 5600 OEM more significant than its lead over its immediate peers. The RX 5600 OEM’s nearest rival, the Intel Arc A570M, is 0.3% faster, meaning the RX 5600 OEM is effectively in a three-way tie with the Arc A570M and the RX 6950 XT, both within 0.5% of its score.

The Verdict

The data points to the NVIDIA Quadro GP100 for anyone prioritizing raw compute performance. Its 40.1% OpenCL lead over the RX 5600 OEM is backed by a 93rd percentile ranking, 16 GB of HBM2 memory, and 10.34 TFLOPS of FP32 throughput. This card is built for large-scale compute tasks, high-resolution texture work, or any workload that can saturate its 732.2 GB/s memory bus. The nearest rivals, such as the RTX A4500 at 4.6% faster, show that the GP100 remains competitive even against newer professional cards.

The AMD Radeon RX 5600 OEM, in contrast, is the choice for efficiency and modern connectivity. Its 125 W TDP, 7 nm process, and PCIe 4.0 support make it a far lighter system integration. Its 87th percentile ranking is respectable, and its Vulkan 1.4 support is ahead of the GP100’s Vulkan 1.3. For users who prioritize lower power draw, newer API support, or PCIe 4.0 bandwidth, the RX 5600 OEM has clear arguments, even though it trails in raw OpenCL scores.

The verdict is not ambiguous: the GP100 wins the only direct benchmark by a wide margin, and its memory and compute specs dominate. The RX 5600 OEM wins on efficiency and platform modernity, but the database shows no test where it beats the GP100. For compute-heavy professional workloads, the GP100 is the only choice from this pair. For low-power consumer builds where raw compute is secondary, the RX 5600 OEM holds its own, but it cannot match the GP100’s performance headroom.