AMD Radeon R9 M375 vs NVIDIA GeForce GTX 1080 Comparison

Head-to-Head Benchmarks

The recorded data contains two directly comparable benchmark results between the NVIDIA GeForce GTX 1080 and the AMD Radeon R9 M375, and in both cases the GTX 1080 takes a commanding lead. The largest margin appears in the Geekbench OpenCL test, where the GTX 1080 scores 51,204 points against 10,457 points for the R9 M375. That is a delta of 389.7 percent, meaning the NVIDIA part delivers nearly five times the compute throughput in this workload. The Geekbench Vulkan test tells a similar story, though the gap narrows somewhat: the GTX 1080 posts 30,398 points versus 9,682 points, a 214 percent advantage. Both deltas are recorded as wins for the GTX 1080, and the head-to-head tally stands at 2 wins for NVIDIA and 0 for AMD.

Context from the database's average benchmark scores reinforces the scale of this separation. The GTX 1080 holds an average benchmark score of 11,960, while the R9 M375 averages 10,070. That is a modest 18.8 percent gap in the aggregate, which stands in sharp contrast to the lopsided head-to-head results. The explanation lies in the benchmark mix: the GTX 1080 has been tested across eleven workloads, including legacy DirectX 9, 10, 11, and 12 tests plus compute and 2D tests, while the R9 M375 has only two recorded results, both in Geekbench. The GTX 1080's average is pulled down by weak legacy DirectX scores, such as 55 points in Passmark DirectX 12 and 93 points in Passmark DirectX 10, whereas its compute score of 7,614 in Passmark GPU Compute and its Geekbench OpenCL score of 51,204 show where its real strength lies.

The percentile rankings also put the two cards in different tiers. The GTX 1080 sits at the 51st percentile among all GPUs in the database, while the R9 M375 sits at the 48th percentile. These are surprisingly close rankings given the head-to-head deltas, but the percentile metric is based on the full benchmark suite, not just the shared tests, and the GTX 1080's low DirectX results drag its standing down. For the workloads where both cards have data, the GTX 1080 is overwhelmingly faster.

Architecture Differences

The two GPUs come from different manufacturing generations and design philosophies. The NVIDIA GeForce GTX 1080 uses the GP104 chip built on TSMC's 16 nm process, with 7,200 million transistors packed into a 314 mm² die. That works out to a transistor density of 22.9 million per square millimeter. The AMD Radeon R9 M375 uses the Tropo chip on TSMC's older 28 nm node, with 1,500 million transistors on a 123 mm² die, giving a density of 12.2 million per square millimeter. The process advantage is substantial: the GTX 1080 crams nearly twice the transistors per area into a die that is more than twice as large.

The GTX 1080 is built on NVIDIA's Pascal architecture and belongs to the GeForce 10-series, released in May 2016. The R9 M375 uses AMD's GCN 1.0 architecture and belongs to the Gem System (R9 M300) generation, released just over a year earlier in May 2015. Both are marked as end-of-life products, and both use a PCIe 3.0 x16 bus interface. The GTX 1080 supports DirectX 12 (12_1), OpenGL 4.6, and Vulkan 1.4, while the R9 M375 supports DirectX 12 (11_1), OpenGL 4.6, and Vulkan 1.2.170. The NVIDIA card has a slightly newer DirectX feature level and a newer Vulkan version.

Compute resources differ dramatically. The GTX 1080 has 2,560 shading units, 160 texture mapping units, and 64 raster operation pipelines. The R9 M375 has 640 shading units, 40 TMUs, and 16 ROPs. That is a 4:1 ratio in shading units, a 4:1 ratio in TMUs, and a 4:1 ratio in ROPs. The clock speeds do not compensate: the GTX 1080 runs at a base of 1607 MHz and a boost of 1733 MHz, while the R9 M375 runs at 1000 MHz base and 1015 MHz boost. The GTX 1080 also has a higher memory clock at 1251 MHz with 10 Gbps effective data rate versus 900 MHz with 1800 Mbps effective for the R9 M375.

Memory configuration is another major divider. The GTX 1080 carries 8 GB of GDDR5X on a 256-bit bus, yielding 320.3 GB/s of bandwidth. The R9 M375 has 2 GB of DDR3 on a 128-bit bus, yielding just 28.80 GB/s. The bandwidth gap is over 11x, which will heavily influence texture-heavy and high-resolution workloads. The GTX 1080 also posts a pixel rate of 110.9 GPixel/s and a texture rate of 277.3 GTexel/s, versus 16.24 GPixel/s and 40.60 GTexel/s for the R9 M375. The FP32 compute rating is 8.873 TFLOPS for the GTX 1080 and 1,299.2 GFLOPS (roughly 1.3 TFLOPS) for the R9 M375. The GTX 1080 also lists FP16 at 138.6 GFLOPS with a 1:64 ratio, while the R9 M375 has no FP16 entry in the database.

The GTX 1080 is a dual-slot card with a 1x 8-pin power connector, a 450 W suggested PSU, and a TDP of 180 W. It measures 267 mm in length, 112 mm in height, and 40 mm in width. The R9 M375 has no recorded TDP, slot width, power connector, suggested PSU, or physical dimensions in the database, which is consistent with a mobile-oriented part. The GTX 1080 also has display outputs listed as 1x DVI, 1x HDMI 2.0, and 3x DisplayPort 1.4a, while the R9 M375 has no display output data recorded.

Where Each One Wins

The GTX 1080 wins every workload where both cards have recorded data. In Geekbench OpenCL, its 51,204 score versus 10,457 is a 389.7 percent advantage, making it the clear choice for general-purpose compute workloads that use OpenCL. In Geekbench Vulkan, the 30,398 versus 9,682 score gives it a 214 percent edge, indicating strong performance in Vulkan-based rendering and compute tasks. The GTX 1080 also holds a broader benchmark footprint: eleven recorded tests covering DirectX 9 through 12, 2D, 3D, and compute, which makes it easier to gauge its behavior across API generations.

The R9 M375 has no recorded wins in the head-to-head data. Its only two benchmarks are Geekbench OpenCL and Vulkan, and it loses both by wide margins. However, the R9 M375's average benchmark score of 10,070 is only 18.8 percent below the GTX 1080's 11,960, and its nearest rival list shows it trading blows with mobile-class parts: it is 0.3 percent ahead of the NVIDIA Quadro K5100M, 0.6 percent ahead of the AMD Radeon Pro 5300M, 1.1 percent ahead of the NVIDIA GeForce GTX 870M, and 2 percent behind the NVIDIA GeForce GTX 950A. The GTX 1080's nearest rivals are all desktop-class parts, including the NVIDIA GeForce GTX 960A (0.3 percent behind), the AMD Radeon RX 6500 XT (1 percent ahead), the NVIDIA GeForce GTX 1660 (2.4 percent ahead), and the AMD Radeon RX 7800 XT (2.9 percent ahead).

For use-case splitting, the GTX 1080 is the obvious pick for any workload that stresses raw compute, high bandwidth, or modern API support. Its 8 GB GDDR5X memory and 320.3 GB/s bandwidth make it suited for high-resolution textures and large datasets, and its 64 ROPs give it strong fill-rate performance. The R9 M375, with its 2 GB DDR3 memory and 28.80 GB/s bandwidth, is limited to lighter workloads; its 640 shading units and 16 ROPs place it in a much lower performance class. The data suggests the R9 M375 would be acceptable for older or less demanding titles, while the GTX 1080 handles the full range of contemporary workloads.

FAQ

Q: How much faster is the GTX 1080 in Geekbench OpenCL?

A: The GTX 1080 scores 51,204 compared to 10,457 for the R9 M375, a delta of 389.7 percent in favor of the NVIDIA card.

Q: What about Vulkan performance?

A: In Geekbench Vulkan, the GTX 1080 scores 30,398 versus 9,682, giving it a 214 percent lead over the R9 M375.

Q: Do the two cards have similar amounts of memory?

A: No. The GTX 1080 has 8 GB of GDDR5X on a 256-bit bus with 320.3 GB/s bandwidth, while the R9 M375 has 2 GB of DDR3 on a 128-bit bus with 28.80 GB/s bandwidth.

Q: Which card has more shading units?

A: The GTX 1080 has 2,560 shading units, while the R9 M375 has 640, a 4:1 ratio. The GTX 1080 also has 160 TMUs versus 40, and 64 ROPs versus 16.

Q: Are these cards still in production?

A: Both are marked as end-of-life in the database. The GTX 1080 was released in May 2016, and the R9 M375 in May 2015.

Q: How do the average benchmark scores compare?

A: The GTX 1080 has an average benchmark score of 11,960, while the R9 M375 averages 10,070, a gap of about 18.8 percent. The GTX 1080 sits at the 51st percentile of all GPUs, and the R9 M375 at the 48th.

The Verdict

The data is unambiguous: the NVIDIA GeForce GTX 1080 is the faster card in every recorded comparison. Its Geekbench OpenCL score is 389.7 percent higher and its Vulkan score is 214 percent higher. The architectural gap explains why. The GTX 1080 has four times the shading units, four times the TMUs, four times the ROPs, over 11 times the memory bandwidth, and a newer process node. The FP32 compute rating of 8.873 TFLOPS against 1,299.2 GFLOPS places the two cards in entirely different performance tiers.

The R9 M375 is not without context. Its average benchmark score of 10,070 places it within 2 percent of several mobile-class competitors, including the NVIDIA GeForce GTX 950A, and its percentile ranking of 48 is only three points below the GTX 1080's 51. But those aggregate figures are heavily influenced by the GTX 1080's weak legacy DirectX scores, which do not reflect its capabilities in modern compute and rendering workloads. For anyone choosing between these two based on the recorded data, the GTX 1080 is the clear performance winner in every shared test, with the only caveat being its larger physical footprint and power requirements, which are not a factor for the R9 M375 since no such data is recorded for that part. The GTX 1080 is the appropriate choice for compute-heavy, bandwidth-heavy, or modern API workloads; the R9 M375 is only relevant in scenarios where the GTX 1080's size, power draw, or availability make it impractical, but the benchmark data itself favors NVIDIA across the board.