AMD Radeon Pro Duo vs NVIDIA GeForce RTX 5080 Mobile Comparison

NVIDIA GeForce RTX 5080 Mobile and AMD Radeon Pro Duo represent two extremes of GPU design separated by nearly a decade of silicon evolution. The RTX 5080 Mobile is an active, modern mobile part built for the GeForce 50-series, while the Radeon Pro Duo is an end-of-life dual-GPU workstation card from 2016. The data shows a single head-to-head benchmark, Geekbench OpenCL, where the NVIDIA part delivers a score of 166,986 against the AMD card’s 35,860, a delta of 365.7%. Despite the Radeon Pro Duo’s higher launch MSRP of 1,499 USD, its average benchmark score of 35,860 places it in the 80th percentile of all GPUs, while the RTX 5080 Mobile’s average of 38,349 lands in the 81st percentile. This page breaks down where each GPU wins, their architectural differences, and what the benchmark data actually means for real-world usage.

Where Each One Wins

The RTX 5080 Mobile wins the only direct comparison available: Geekbench OpenCL. Its score of 166,986 is 365.7% higher than the Radeon Pro Duo’s 35,860, a massive margin that reflects not just raw compute but the efficiency of a modern architecture. Beyond that single test, the NVIDIA part’s broader benchmark suite shows strength across multiple APIs: it scores 4,952 in 3DMark Steel Nomad DX12, 169,754 in Geekbench Vulkan, and 27,711 in Passmark G3D. The Radeon Pro Duo has no corresponding scores in those tests, so its only measurable win is the absence of competition—it simply has no data for DirectX 12, Vulkan, or Passmark workloads. In terms of percentile ranking, the two are nearly tied: 81st for the RTX 5080 Mobile versus 80th for the Radeon Pro Duo, which suggests that while the NVIDIA part is decisively ahead in the one shared test, the AMD card’s historical performance still holds up as an average GPU.

The use-case split is clear. The RTX 5080 Mobile dominates compute workloads like OpenCL, where its 23.04 TFLOPS FP32 throughput crushes the Radeon Pro Duo’s 8.192 TFLOPS. For modern gaming and DirectX 12 Ultimate applications, the NVIDIA part has the edge with a score of 116 in Passmark DirectX 12, though this number is low in absolute terms, likely reflecting a mobile power-limited scenario. The Radeon Pro Duo, with its dual-GPU design and 4 GB HBM memory, was built for professional rendering and compute tasks that could leverage its 4096-bit memory bus, but the data shows it cannot keep pace with the RTX 5080 Mobile in raw OpenCL throughput. The NVIDIA card’s 16 GB GDDR7 memory and 896.0 GB/s bandwidth also give it a substantial advantage in memory-heavy workloads, while the AMD card’s 512.0 GB/s bandwidth is half that despite a wider bus.

Architecture Differences

The RTX 5080 Mobile is built on NVIDIA’s Blackwell 2.0 architecture using the GB203 chip, fabricated on a 5 nm process at TSMC with 45,600 million transistors on a 378 mm² die. This gives it a transistor density of 120.6 million per mm², a figure that dwarfs the Radeon Pro Duo’s 14.9 million per mm². The AMD card uses the Capsaicin chip with GCN 3.0 architecture, also made by TSMC but on a 28 nm process, packing 8,900 million transistors across a larger 596 mm² die. The process node difference is stark: 5 nm versus 28 nm, which explains the RTX 5080 Mobile’s superior efficiency and lower power draw of 80 W TDP compared to the Radeon Pro Duo’s 350 W TDP.

Core counts reflect their different eras. The RTX 5080 Mobile has 7,680 shading units, 240 TMUs, and 96 ROPs, alongside 60 RT cores and 240 tensor cores. The Radeon Pro Duo has 4,096 shading units, 256 TMUs, and 64 ROPs, but no RT or tensor cores, as those features did not exist in GCN 3.0. The NVIDIA part’s pixel rate is 144.0 GPixel/s versus 64.00 GPixel/s for the AMD card, and its texture rate is 360.0 GTexel/s versus 256.0 GTexel/s. Memory configurations differ fundamentally: the RTX 5080 Mobile uses 16 GB of GDDR7 on a 256-bit bus with 896.0 GB/s bandwidth, while the Radeon Pro Duo uses 4 GB of HBM on a 4096-bit bus with 512.0 GB/s bandwidth. The AMD card’s wider bus cannot compensate for the lower clock speed, as its memory runs at 500 MHz (1000 Mbps effective) versus the NVIDIA part’s 1750 MHz (28 Gbps effective).

FAQ

Q: Which GPU has a higher average benchmark score?

A: The NVIDIA GeForce RTX 5080 Mobile has an average benchmark score of 38,349, while the AMD Radeon Pro Duo scores 35,860. The NVIDIA part also holds a 81st percentile ranking versus the AMD card’s 80th.

Q: What is the performance gap in the only shared benchmark?

A: In Geekbench OpenCL, the RTX 5080 Mobile scores 166,986 against the Radeon Pro Duo’s 35,860, giving the NVIDIA part a 365.7% advantage.

Q: How do their memory subsystems compare?

A: The RTX 5080 Mobile has 16 GB of GDDR7 on a 256-bit bus with 896.0 GB/s bandwidth. The Radeon Pro Duo has 4 GB of HBM on a 4096-bit bus with 512.0 GB/s bandwidth. The NVIDIA part’s bandwidth is higher despite a narrower bus.

Q: Does the Radeon Pro Duo support ray tracing or tensor operations?

A: No. The Radeon Pro Duo has no RT cores or tensor cores, while the RTX 5080 Mobile includes 60 RT cores and 240 tensor cores for these workloads.

Q: What is the power consumption difference?

A: The RTX 5080 Mobile has an 80 W TDP, while the Radeon Pro Duo has a 350 W TDP. The AMD card also requires 3x 8-pin power connectors and a 750 W suggested PSU, whereas the NVIDIA part uses no power connectors.

Q: Which GPU is newer and still in production?

A: The RTX 5080 Mobile was released on 2025-04-01 and is marked as Active in production. The Radeon Pro Duo was released on 2016-04-25 and is End-of-life, with its successor listed as the Radeon Pro Polaris.

Specification Differences

The two GPUs differ across nearly every specification field. The RTX 5080 Mobile uses a 5 nm process with 45,600 million transistors on a 378 mm² die, while the Radeon Pro Duo uses 28 nm with 8,900 million transistors on a 596 mm² die. Clock speeds are not directly comparable: the NVIDIA part lists a base clock of 975 MHz and boost of 1500 MHz, while the AMD card’s base and boost clocks are null in the data. Memory type, size, and bus width all differ: GDDR7 16 GB on 256-bit versus HBM 4 GB on 4096-bit. The RTX 5080 Mobile has 7,680 shading units, 240 TMUs, 96 ROPs, 60 RT cores, and 240 tensor cores; the Radeon Pro Duo has 4,096 shading units, 256 TMUs, and 64 ROPs, with no RT or tensor cores. The NVIDIA part’s TDP is 80 W with an IGP slot width and no power connectors, while the AMD card is 350 W, dual-slot, and requires 3x 8-pin connectors plus a 750 W PSU. Bus interfaces differ: PCIe 5.0 x16 versus PCIe 3.0 x16. Display outputs are portable-device-dependent on the NVIDIA part, while the AMD card has 1x HDMI 1.4a and 3x DisplayPort 1.2. The RTX 5080 Mobile supports DirectX 12 Ultimate (12_2), Vulkan 1.4, and OpenGL 4.6; the Radeon Pro Duo supports DirectX 12 (12_0), Vulkan 1.2.170, and OpenGL 4.6.

Head-to-Head Benchmarks

The only direct benchmark comparison available is Geekbench OpenCL, and it is a decisive victory for the NVIDIA GeForce RTX 5080 Mobile. The NVIDIA part scores 166,986, while the AMD Radeon Pro Duo scores 35,860, resulting in a delta of 365.7%. This means the RTX 5080 Mobile is over 4.6 times faster in this compute test. To put that in perspective, the RTX 5080 Mobile’s nearest rivals—the GeForce MX570, RTX 4080 Mobile, MX570 A, and Radeon Pro 580X—are all within 1% of its average score, showing how close modern mid-range parts are. The Radeon Pro Duo’s nearest rivals, including the Quadro GV100 and RTX 5070 Ti Mobile, are also within 2% of its average, which suggests the AMD card’s 35,860 OpenCL score is roughly in line with its historical peers.

The RTX 5080 Mobile’s other benchmark results reinforce its lead. In Geekbench Vulkan, it scores 169,754, and in 3DMark Steel Nomad DX12, it hits 4,952. Passmark tests show 27,711 in G3D, 12,134 in GPU Compute, and lower scores in DirectX 9, 10, 11, and 12 (314, 171, 253, and 116 respectively). These figures are not comparable to the Radeon Pro Duo, as the AMD card lacks scores for those tests, but they illustrate the NVIDIA part’s versatility across legacy and modern APIs. The Radeon Pro Duo’s sole benchmark score of 35,860 in OpenCL is its only data point, and it falls short of the RTX 5080 Mobile’s OpenCL result by a wide margin. The data shows that the RTX 5080 Mobile is not just faster in the shared test but also offers a more complete feature set with RT cores, tensor cores, and newer API support, making it the superior choice for any workload where compute performance matters.