AMD Radeon Pro 5300M vs NVIDIA GeForce GTX 465 Comparison

The AMD Radeon Pro 5300M and the NVIDIA GeForce GTX 465 are separated by nearly a decade of GPU architecture, and the benchmark data reflects a complete generational overhaul. In the only directly comparable test, the Radeon Pro 5300M delivers a 214.7% higher Geekbench OpenCL score than the GTX 465, making the newer mobile part the definitive winner in raw compute throughput. However, the GTX 465 holds its own as a legacy desktop piece with distinct interface and connectivity traits, and the choice between them depends entirely on whether the priority is modern efficiency and compute power or a functioning piece of 2010-era hardware.

Where Each One Wins

The AMD Radeon Pro 5300M wins every measurable performance category in the available data. Its single head-to-head benchmark result shows a Geekbench OpenCL score of 29252 against the GTX 465’s 9294, a 214.7% advantage. This is not a marginal lead; it is a dominant, multi-generational leap in compute capability. Beyond the direct comparison, the Pro 5300M also posts a richer benchmark profile, including Geekbench Metal and Vulkan scores of 33626 and 27912 respectively, alongside a Passmark G3D score of 5918. The GTX 465’s only listed benchmark is the OpenCL test, meaning its performance scope is far narrower in this dataset.

The NVIDIA GeForce GTX 465 wins in legacy connectivity and physical integration. It offers a dual-slot form factor, two DVI outputs plus a mini-HDMI 1.3a port, and a 241 mm (9.5 inch) length, making it a conventional desktop card with standard display options. The Pro 5300M, by contrast, lists "Portable Device Dependent" for display outputs, meaning its connectivity is tied to the specific laptop chassis. The GTX 465 also carries a 256-bit memory bus and 1024 MB of GDDR5, which, while small by modern standards, provides a wider bus than the Pro 5300M’s 128-bit interface. For a user needing a standalone card with fixed DVI outputs, the GTX 465 is the only one of the two that offers that out-of-the-box.

Architecture Differences

The architectural gap is stark. The AMD Radeon Pro 5300M is built on RDNA 1.0 using a 7 nm process at TSMC, packing 6,400 million transistors into a 158 mm² die. This yields a transistor density of 40.5 million per square millimeter, reflecting a modern, tightly packed design. The NVIDIA GeForce GTX 465 uses the older Fermi architecture on a 40 nm process, also at TSMC, but with only 3,100 million transistors spread across a massive 529 mm² die, resulting in a density of just 5.9 million per square millimeter. The Pro 5300M achieves more than double the transistor count in less than a third of the silicon area, which directly explains its efficiency and performance advantages.

Core configuration diverges significantly. The Pro 5300M features 1280 shading units, 80 texture mapping units, and 32 ROPs, while the GTX 465 has 352 shading units, 44 TMUs, and 32 ROPs. The shading unit count is nearly 3.6 times higher on the AMD part, driving its compute dominance. Clock speeds tell a similar story: the Pro 5300M runs at a 1000 MHz base and 1250 MHz boost, whereas the GTX 465 has no listed base or boost clocks, only a memory clock of 802 MHz (3.2 Gbps effective). The Pro 5300M’s memory operates at 1500 MHz (12 Gbps effective) on GDDR6, while the GTX 465 uses GDDR5 at a much lower effective speed.

Memory architecture is another clear divide. The Pro 5300M has 4 GB of GDDR6 on a 128-bit bus, delivering 192.0 GB/s of bandwidth. The GTX 465 has 1024 MB of GDDR5 on a 256-bit bus, yielding 102.7 GB/s. Despite the wider bus, the GTX 465’s lower memory clock means it still loses on bandwidth by a factor of roughly 1.9. The Pro 5300M also supports PCIe 4.0 x8, while the GTX 465 is limited to PCIe 2.0 x16. Power consumption is a major differentiator: the Pro 5300M is rated at 85 W TDP with no power connectors, whereas the GTX 465 draws 200 W and requires two 6-pin connectors and a 550 W suggested PSU.

Head-to-Head Benchmarks

The only direct benchmark comparison available is Geekbench OpenCL, and it is decisive. The AMD Radeon Pro 5300M scores 29252, while the NVIDIA GeForce GTX 465 scores 9294. The delta is 214.7%, meaning the Pro 5300M more than triples the GTX 465’s output. This result aligns with the architectural disparity: the Pro 5300M’s 3.200 TFLOPS FP32 throughput versus the GTX 465’s 855.4 GFLOPS is a 3.7x raw compute advantage. In memory bandwidth, the Pro 5300M’s 192.0 GB/s eclipses the GTX 465’s 102.7 GB/s by 87%, which feeds its higher texture and pixel rates — 100.0 GTexel/s and 40.00 GPixel/s versus 26.75 GTexel/s and 13.38 GPixel/s.

The Pro 5300M’s additional benchmark scores provide context for its overall standing. Its Geekbench Metal score of 33626 and Vulkan score of 27912 indicate strong API support across modern interfaces, while its Passmark G3D score of 5918 places it in the 48th percentile of all GPUs. The GTX 465, with only the OpenCL score, sits at the 46th percentile, a two-percentile gap that understates the massive per-test difference. The average benchmark score for the Pro 5300M is 10013, compared to 9294 for the GTX 465, a 7.7% advantage overall, but again, that average includes only one test for the NVIDIA part.

In terms of nearest rivals, the Pro 5300M’s average score of 10013 is nearly identical to the NVIDIA Quadro K5100M’s 10043 (a -0.3% delta) and slightly above the GeForce GTX 870M’s 9959 (+0.5%). The GTX 465’s 9294 average is within 0.1% of the GeForce GTX 850M’s 9302 and trails the GTX 960’s 9273 by 0.2%. These comparisons show that the Pro 5300M competes with mid-range mobile GPUs from a later era, while the GTX 465 aligns with entry-level parts from its own generation.

The Verdict

The data is unambiguous for compute workloads: the AMD Radeon Pro 5300M is the superior card. Its 214.7% lead in OpenCL performance, combined with higher memory bandwidth, more shading units, and a 7 nm process, makes it the only rational choice for any modern application that uses GPU acceleration. The Pro 5300M’s support for DirectX 12 (12_1), Vulkan 1.4, and OpenGL 4.6 ensures broad compatibility with current software, whereas the GTX 465 only lists DirectX 12 (11_0) and OpenGL 4.6, with no Vulkan support. For creative professionals or users running compute-heavy tasks, the Pro 5300M wins outright.

The NVIDIA GeForce GTX 465 is only preferable in a narrow legacy scenario. Its dual-slot design, 241 mm length, and DVI/mini-HDMI outputs make it a drop-in card for older desktop systems that require those specific physical connections. Its 2x 6-pin power requirement and 550 W suggested PSU are heavy by modern standards, but for a retro build or a machine lacking PCIe 4.0 support, the GTX 465 functions as intended. It also has a lower memory capacity at 1024 MB, which will limit it to older games and applications. Given the performance gap, the GTX 465 is not a competitive alternative; it is a historical artifact.

FAQ

Q: How much faster is the AMD Radeon Pro 5300M than the NVIDIA GeForce GTX 465 in OpenCL?

A: The Pro 5300M scores 29252 in Geekbench OpenCL, while the GTX 465 scores 9294, giving the AMD part a 214.7% higher result.

Q: Which GPU has more memory bandwidth?

A: The AMD Radeon Pro 5300M has 192.0 GB/s of bandwidth, compared to the NVIDIA GeForce GTX 465’s 102.7 GB/s, a difference of about 87%.

Q: What are the power requirements for each card?

A: The Radeon Pro 5300M is rated at 85 W TDP with no power connectors, while the GeForce GTX 465 is rated at 200 W and requires two 6-pin connectors and a 550 W suggested PSU.

Q: Does the NVIDIA GeForce GTX 465 support Vulkan?

A: No, the GTX 465 lists no Vulkan API support, whereas the Radeon Pro 5300M supports Vulkan 1.4.

Q: Which card has more shading units?

A: The Radeon Pro 5300M has 1280 shading units, while the GeForce GTX 465 has 352, making the AMD part nearly 3.6 times higher in this metric.

Q: What is the memory capacity difference?

A: The Radeon Pro 5300M has 4 GB of GDDR6, while the GeForce GTX 465 has 1024 MB of GDDR5, a four-fold difference in capacity.

Specification Differences

| Specification | AMD Radeon Pro 5300M | NVIDIA GeForce GTX 465 |

|----------------|-----------------------|------------------------|

| Architecture | RDNA 1.0 | Fermi |

| Process Node | 7 nm | 40 nm |

| Transistors | 6,400 million | 3,100 million |

| Die Size | 158 mm² | 529 mm² |

| Transistor Density | 40.5M / mm² | 5.9M / mm² |

| Base Clock | 1000 MHz | None |

| Boost Clock | 1250 MHz | None |

| Memory Clock | 1500 MHz / 12 Gbps effective | 802 MHz / 3.2 Gbps effective |

| Memory Size | 4 GB | 1024 MB |

| Memory Type | GDDR6 | GDDR5 |

| Memory Bus Width | 128 bit | 256 bit |

| Memory Bandwidth | 192.0 GB/s | 102.7 GB/s |

| Shading Units | 1280 | 352 |

| TMUs | 80 | 44 |

| ROPs | 32 | 32 |

| Pixel Rate | 40.00 GPixel/s | 13.38 GPixel/s |

| Texture Rate | 100.0 GTexel/s | 26.75 GTexel/s |

| FP32 | 3.200 TFLOPS | 855.4 GFLOPS |

| FP16 | 6.400 TFLOPS | None |

| TDP | 85 W | 200 W |

| Slot Width | None | Dual-slot |

| Power Connectors | None | 2x 6-pin |

| Suggested PSU | None | 550 W |

| Bus Interface | PCIe 4.0 x8 | PCIe 2.0 x16 |

| Display Outputs | Portable Device Dependent | 2x DVI, 1x mini-HDMI 1.3a |

| DirectX | 12 (12_1) | 12 (11_0) |

| Vulkan | 1.4 | None |

| Release Date | 2019-11-12 | 2010-05-30 |

| Launch MSRP | None | 279 USD |