AMD Instinct MI350X vs NVIDIA GeForce RTX 4060 Mobile Comparison

Head-to-Head Benchmarks

The data for these two accelerators is starkly asymmetric. The AMD Instinct MI350X has no recorded benchmark entries in the database, leaving its performance profile entirely defined by its theoretical specifications. The NVIDIA GeForce RTX 4060 Mobile, by contrast, carries a full set of nine benchmark results, giving it a percentile rank of 67 among all GPUs and an average benchmark score of 22,729.

The RTX 4060 Mobile's scores cluster around its closest rivals. It trails the NVIDIA GeForce RTX 2080 by 0.7% (22,895 vs. 22,729), sits ahead of the AMD Radeon RX 7700 XT by 0.8% (22,549 vs. 22,729), and edges past the Intel Arc B580 by 1.3% (23,021 vs. 22,729). The newest rival, the NVIDIA GeForce RTX 5060 Mobile, sits 1.3% behind with a score of 22,435. These deltas indicate the RTX 4060 Mobile sits in a tightly contested performance band, with its closest competitors within roughly one point percent in either direction.

The MI350X's absence from the benchmark suite means no head-to-head scores exist. The only numerical comparison available is architectural: the MI350X lists FP32 throughput of 72.09 TFLOPS, while the RTX 4060 Mobile lists 11.61 TFLOPS. That is a 6.2x gap in raw shader math. Texture rate shows a similar chasm, with the MI350X at 2,252.8 GTexel/s versus 181.4 GTexel/s for the RTX 4060 Mobile, a 12.4x difference. Memory bandwidth diverges even further: 8.19 TB/s against 256.0 GB/s, a 32x spread. These are not competitive numbers; they are different product categories entirely.

Where Each One Wins

The RTX 4060 Mobile wins in every measured benchmark category because it is the only one with measurements. Its PassMark G3D score of 17,469 and Geekbench Vulkan score of 89,569 show a functional graphics pipeline. The RTX 4060 Mobile also supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4, making it usable across modern graphics workloads. It has 48 ROPs and a pixel rate of 90.72 GPixel/s, confirming a real rasterization path.

The MI350X wins on every raw specification that matters for compute density. It has 16,384 shading units versus 3,072, 1,024 TMUs versus 96, and 288 GB of HBM3e memory versus 8 GB of GDDR6. Its FP32 and FP16 both sit at 72.09 TFLOPS with a 1:1 ratio, whereas the RTX 4060 Mobile also runs FP32 and FP16 at 1:1 but at 11.61 TFLOPS. The MI350X carries 185,000 million transistors on a 2,380 mm² die, against 18,900 million transistors on 159 mm² for the RTX 4060 Mobile. The transistor density flips the comparison: the RTX 4060 Mobile packs 118.9M transistors per mm² versus 77.7M for the MI350X, indicating the smaller chip uses a denser process layout.

The MI350X has a pixel rate of 0 MPixel/s and zero ROPs. It also lists no display outputs. The RTX 4060 Mobile has display outputs described as "Portable Device Dependent." For rendering frames to a screen, the RTX 4060 Mobile is the only functional option. For compute throughput, the MI350X's specification sheet dominates every metric.

Architecture Differences

The two chips come from different design philosophies. The MI350X uses CDNA 4.0 architecture on a 3 nm TSMC process, built for the Instinct (MIx) generation. Its predecessor is the Radeon Instinct line. The RTX 4060 Mobile uses Ada Lovelace on a 5 nm TSMC process, belonging to the GeForce 40 Mobile generation, with the GeForce 30 Mobile as predecessor and GeForce 50 Mobile as successor.

The MI350X chip is labeled "MI350 256CU" and uses 8192-bit HBM3e memory. The RTX 4060 Mobile uses the AD107 chip with a 128-bit GDDR6 bus. Memory clocks differ in effective rate: both list 2000 MHz base memory clock, but the effective data rate is 8 Gbps for the MI350X and 16 Gbps for the RTX 4060 Mobile. The RTX 4060 Mobile compensates for its narrow bus with a faster per-pin data rate, but the MI350X's 8192-bit bus delivers 8.19 TB/s against 256.0 GB/s.

The MI350X has no RT cores and no tensor cores listed. The RTX 4060 Mobile includes 24 RT cores and 96 tensor cores, which are absent from the MI350X's specification sheet. The MI350X also lists no API support (DirectX, OpenGL, Vulkan all N/A), while the RTX 4060 Mobile supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4.

Power and physical design differ accordingly. The MI350X has a TDP of 1000 W and a suggested PSU of 1400 W, while the RTX 4060 Mobile has a TDP of 115 W and no suggested PSU listed. The MI350X is an OAM Module with dimensions of 102 mm length and 165 mm width; the RTX 4060 Mobile is an IGP with no dimensions recorded. The MI350X uses PCIe 5.0 x16, the RTX 4060 Mobile uses PCIe 4.0 x8. Neither uses external power connectors.

FAQ

Q: Which GPU has higher FP32 compute?

A: The AMD Instinct MI350X lists FP32 at 72.09 TFLOPS, which is 6.2x higher than the NVIDIA GeForce RTX 4060 Mobile's 11.61 TFLOPS.

Q: Does the MI350X support DirectX or Vulkan?

A: No. The MI350X lists DirectX, OpenGL, and Vulkan as N/A. The RTX 4060 Mobile supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4.

Q: Which GPU has more memory and bandwidth?

A: The MI350X has 288 GB of HBM3e on an 8192-bit bus with 8.19 TB/s bandwidth. The RTX 4060 Mobile has 8 GB of GDDR6 on a 128-bit bus with 256.0 GB/s bandwidth.

Q: How does the RTX 4060 Mobile compare to its nearest rivals?

A: Its average benchmark score of 22,729 is 0.7% below the NVIDIA GeForce RTX 2080 (22,895), 0.8% above the AMD Radeon RX 7700 XT (22,549), 1.3% below the Intel Arc B580 (23,021), and 1.3% above the NVIDIA GeForce RTX 5060 Mobile (22,435).

Q: Which GPU has higher transistor density?

A: The RTX 4060 Mobile has 118.9M transistors per mm² (18,900 million on 159 mm²), while the MI350X has 77.7M per mm² (185,000 million on 2,380 mm²).

Q: What are the power requirements?

A: The MI350X has a TDP of 1000 W and suggests a 1400 W PSU. The RTX 4060 Mobile has a TDP of 115 W and lists no suggested PSU.

The Verdict

The recorded data separates these two products cleanly. The NVIDIA GeForce RTX 4060 Mobile is the only one with benchmark results, a percentile rank of 67, and a functional graphics stack. Any workload requiring rendering, display output, or standard graphics APIs falls to it by default. Its performance sits within 1.3% of four nearby rivals, indicating a competitive mid-range mobile GPU position.

The AMD Instinct MI350X has no measured results, no display outputs, no ROPs, and no graphics API support. Its role is purely computational. The specification sheet describes 72.09 TFLOPS of FP32, 8.19 TB/s of memory bandwidth, and 288 GB of HBM3e. These numbers place it in an entirely different performance class from the RTX 4060 Mobile, but the database contains no benchmark evidence to confirm real-world behavior.

The buyer decision depends on workload type, not performance ranking. For an interactive graphics workload, the RTX 4060 Mobile is the only candidate with data showing it works. For a high-throughput compute installation, the MI350X's specifications dwarf the RTX 4060 Mobile in every raw compute metric, but its 1000 W TDP, OAM Module form factor, and lack of any benchmark scores mean it serves a server rack, not a desktop or laptop. The RTX 4060 Mobile's 115 W TDP and IGP form factor suit portable devices.

The data does not support a direct comparison. The two products share no common benchmark entries, no common power envelope, and no common physical format. The RTX 4060 Mobile exists in a measurable market segment with known rivals. The MI350X exists as a specification sheet with a release date of 2025-06-11 and a percentile rank of 50, which the database assigns despite its zero average benchmark score.

Specification Differences

| Field | AMD Instinct MI350X | NVIDIA GeForce RTX 4060 Mobile |

|---|---|---|

| Architecture | CDNA 4.0 | Ada Lovelace |

| Process node | 3 nm | 5 nm |

| Transistors | 185,000 million | 18,900 million |

| Die size | 2380 mm² | 159 mm² |

| Transistor density | 77.7M / mm² | 118.9M / mm² |

| Base clock | 1000 MHz | 1545 MHz |

| Boost clock | 2200 MHz | 1890 MHz |

| Memory size | 288 GB | 8 GB |

| Memory type | HBM3e | GDDR6 |

| Memory bus | 8192 bit | 128 bit |

| Memory bandwidth | 8.19 TB/s | 256.0 GB/s |

| Effective memory rate | 8 Gbps | 16 Gbps |

| Shading units | 16384 | 3072 |

| TMUs | 1024 | 96 |

| ROPs | 0 | 48 |

| RT cores | N/A | 24 |

| Tensor cores | N/A | 96 |

| Pixel rate | 0 MPixel/s | 90.72 GPixel/s |

| Texture rate | 2,252.8 GTexel/s | 181.4 GTexel/s |

| FP32 | 72.09 TFLOPS | 11.61 TFLOPS |

| FP16 | 72.09 TFLOPS (1:1) | 11.61 TFLOPS (1:1) |

| TDP | 1000 W | 115 W |

| Suggested PSU | 1400 W | None |

| Slot width | OAM Module | IGP |

| Bus interface | PCIe 5.0 x16 | PCIe 4.0 x8 |

| Display outputs | No outputs | Portable Device Dependent |

| DirectX | N/A | 12 Ultimate (12_2) |

| OpenGL | N/A | 4.6 |

| Vulkan | N/A | 1.4 |

| Release date | 2025-06-11 | 2023-01-02 |

| Production status | Not listed | Active |

| Predecessor | Radeon Instinct | GeForce 30 Mobile |

| Successor | None | GeForce 50 Mobile |

| Percentile vs all GPUs | 50 | 67 |

| Average benchmark score | 0 | 22,729 |

The remaining fields are identical or unlisted: both use TSMC as foundry, both have no power connectors, both lack a game clock and codename, and both have no launch MSRP recorded. The MI350X dimensions are 102 mm by 165 mm; the RTX 4060 Mobile has no dimensions listed.