AMD Instinct MI350X vs NVIDIA GB10 Comparison

The AMD Instinct MI350X and NVIDIA GB10 occupy different ends of the compute spectrum, and the recorded data makes that separation explicit. The MI350X is a 1000 W OAM module built for scale-out acceleration, while the GB10 is a 140 W integrated graphics processor aimed at dense, low-power deployments. The MI350X has no benchmark entries in the database, giving it a 50th percentile rank among all GPUs with an average score of zero. The GB10, by contrast, has two recorded benchmark results, an average score of 117,393, and sits at the 95th percentile, placing it ahead of 95% of all tracked GPUs in the database. The data does not support direct performance parity; it supports a functional split.

The Verdict

The database positions the NVIDIA GB10 as the only one of the two with measurable performance data. Its Geekbench OpenCL score is 120,137 and its Geekbench Vulkan score is 114,648, producing an average of 117,393. That average places it 0.3% ahead of the NVIDIA RTX 4000 SFF Ada Generation, 1.3% behind the AMD Radeon PRO W7700, 2.6% ahead of the NVIDIA Tesla V100 SXM2 16 GB, and 3% ahead of the NVIDIA RTX A5500 Mobile. These deltas are narrow, indicating that the GB10 is competitive with a specific cluster of workstation and server GPUs, but it is not dominant over them in the recorded tests.

The AMD Instinct MI350X has zero benchmark scores in the database, so its percentile rank of 50 is an artifact of missing data, not a statement of measured capability. The MI350X is the choice for workloads that require massive memory capacity and bandwidth, based on its specifications. It carries 288 GB of HBM3e memory on an 8192-bit bus, delivering 8.19 TB/s of bandwidth. The GB10 offers 128 GB of LPDDR5X on a 256-bit bus, with 273.2 GB/s. For any application governed by memory throughput, the MI350X provides a recorded 30x bandwidth advantage, a gap that no compute core count can close.

For users who need a working, measured GPU today, the GB10 is the only option with verified performance. For users who need maximum memory capacity and bandwidth in a single accelerator, the MI350X is the only option that provides it. The GB10 also includes display output via one HDMI port, while the MI350X has no display outputs, so the GB10 is the only one of the pair that can drive a monitor directly. The production status field confirms the GB10 is Active, while the MI350X has no recorded production status. The GB10 has a launch MSRP of 3,999 USD, which is the only pricing data in the record.

Architecture Differences

The MI350X uses the CDNA 4.0 architecture on a 3 nm TSMC process, while the GB10 uses the Blackwell 2.0 architecture on a 5 nm TSMC process. The MI350X chip is labeled MI350 256CU, and the GB10 chip is labeled GB20B. The MI350X integrates 185,000 million transistors on a 2380 mm² die, yielding a transistor density of 77.7 million per square millimeter. The GB10 has no recorded transistor count or density, but its die size is 382 mm², roughly one-sixth the area of the MI350X. The MI350X generation is listed as Instinct (MIx), while the GB10 generation is Server Blackwell (Bxx).

The MI350X implements 16,384 shading units, 1,024 texture mapping units, and zero ROPs, with a pixel rate of 0 MPixel/s. The GB10 implements 6,144 shading units, 384 TMUs, and 48 ROPs, with a pixel rate of 116.1 GPixel/s. The GB10 has 48 ray tracing cores and 384 tensor cores. The MI350X has no recorded ray tracing core or tensor core counts. The MI350X has a texture rate of 2,252.8 GTexel/s, while the GB10 reaches 928.5 GTexel/s.

The MI350X is built on CDNA 4.0, which is a compute-focused architecture with no display path. The GB10 is built on Blackwell 2.0, which includes a display controller capable of one HDMI output. The MI350X does not support DirectX, OpenGL, or Vulkan; the GB10 also reports N/A for all three APIs. Both devices use a PCIe 5.0 x16 bus interface. The MI350X requires no power connectors on the card itself, but its suggested power supply is 1400 W. The GB10 also uses no power connectors, but its suggested power supply is 300 W.

The MI350X is an OAM module, which is a board form factor designed for server chassis, not for desktop installation. The GB10 is an IGP, an integrated graphics processor, which is designed to be mounted directly onto a carrier board. The MI350X measures 102 mm in length and 165 mm in width. The GB10 measures 150 mm in length, 51 mm in height, and 150 mm in width. The MI350X has no display outputs; the GB10 has one HDMI output. The GB10 is marked as Active in production, with a predecessor of Server Hopper and a successor of Server Rubin. The MI350X has a predecessor of Radeon Instinct and no recorded successor.

Head-to-Head Benchmarks

The database contains no direct head-to-head benchmark entries for the MI350X versus the GB10. Both devices have zero entries in the head-to-head field, and the win counters read zero for both. Every comparison between them must therefore be drawn from their separate specification records and the GB10's standalone benchmark results.

The GB10 demonstrates its measured performance through two Geekbench tests. Its OpenCL score is 120,137, and its Vulkan score is 114,648, a difference of 5,489 points. The Vulkan result is 4.6% lower than the OpenCL result, which suggests the GB10 is slightly stronger under the OpenCL compute workload in the recorded data. The average benchmark score of 117,393 is the reference point for its rival comparisons. Against the NVIDIA RTX 4000 SFF Ada Generation, the GB10 is 0.3% faster. Against the AMD Radeon PRO W7700, it is 1.3% slower. Against the NVIDIA Tesla V100 SXM2 16 GB, it is 2.6% faster. Against the NVIDIA RTX A5500 Mobile, it is 3% faster. These margins are all within a single-digit percentage range, so the GB10 sits in a tight performance band rather than at the top of it.

The MI350X has no comparable benchmark scores, so the only quantitative comparisons are architectural. Its FP32 throughput is 72.09 TFLOPS, and its FP16 throughput is also 72.09 TFLOPS at a 1:1 ratio. The GB10 delivers 29.71 TFLOPS in FP32 and 29.71 TFLOPS in FP16, also at a 1:1 ratio. The MI350X therefore provides 2.43 times the FP32 throughput of the GB10 on paper. Its texture rate of 2,252.8 GTexel/s is 2.43 times the GB10's 928.5 GTexel/s. The MI350X has 2.67 times the shading units of the GB10, 2.67 times the TMUs, and 2.25 times the memory capacity. Its memory bandwidth of 8.19 TB/s is 29.98 times the GB10's 273.2 GB/s.

The MI350X does have a massive power requirement. Its TDP is 1000 W, compared to the GB10's 140 W, a factor of 7.14. The suggested power supply for the MI350X is 1400 W, while the GB10 needs only 300 W, a factor of 4.67. The MI350X also has a larger die at 2380 mm² versus 382 mm², a factor of 6.23. These figures indicate that the MI350X trades power and size for raw compute throughput and memory bandwidth, while the GB10 trades throughput for a much smaller physical footprint and lower system power demand.

Specification Differences

The two devices differ across nearly every recorded specification. The MI350X is manufactured by AMD, and the GB10 is manufactured by NVIDIA. The MI350X uses a 3 nm process, and the GB10 uses a 5 nm process. The MI350X die is 2380 mm², and the GB10 die is 382 mm². The MI350X has 185,000 million transistors, and the GB10 has no recorded transistor count. The MI350X transistor density is 77.7 million per mm², and the GB10 has no recorded density.

The base clock of the MI350X is 1000 MHz, while the GB10 base clock is 1665 MHz. The boost clock of the MI350X is 2200 MHz, while the GB10 boost clock is 2418 MHz. The memory clock of the MI350X is 2000 MHz with 8 Gbps effective transfer, and the GB10 memory clock is 1067 MHz with 8.5 Gbps effective transfer. The MI350X has 288 GB of HBM3e memory, and the GB10 has 128 GB of LPDDR5X memory. The memory bus width is 8192 bits for the MI350X and 256 bits for the GB10. Memory bandwidth is 8.19 TB/s for the MI350X and 273.2 GB/s for the GB10.

The MI350X has 16,384 shading units, and the GB10 has 6,144. The MI350X has 1,024 TMUs, and the GB10 has 384. The MI350X has 0 ROPs, and the GB10 has 48. The MI350X has no recorded ray tracing cores, and the GB10 has 48. The MI350X has no recorded tensor cores, and the GB10 has 384. The pixel rate of the MI350X is 0 MPixel/s, and the GB10 is 116.1 GPixel/s. The texture rate of the MI350X is 2,252.8 GTexel/s, and the GB10 is 928.5 GTexel/s. FP32 performance is 72.09 TFLOPS for the MI350X and 29.71 TFLOPS for the GB10. FP16 performance is 72.09 TFLOPS for the MI350X and 29.71 TFLOPS for the GB10.

The TDP is 1000 W for the MI350X and 140 W for the GB10. The MI350X is an OAM module, and the GB10 is an IGP. Neither uses power connectors. The suggested PSU is 1400 W for the MI350X and 300 W for the GB10. Both use PCIe 5.0 x16. The MI350X has no display outputs, and the GB10 has one HDMI output. The MI350X measures 102 mm by 165 mm, and the GB10 measures 150 mm by 51 mm by 150 mm. The MI350X released on 2025-06-11, and the GB10 released on 2025-10-14. The GB10 has a launch MSRP of 3,999 USD; the MI350X has no recorded launch MSRP.

FAQ

Q: Which GPU has a higher average benchmark score in the database?

A: The NVIDIA GB10 has an average benchmark score of 117,393. The AMD Instinct MI350X has no recorded benchmark scores, giving it an average score of zero.

Q: How does the GB10 compare to its nearest rivals?

A: The GB10 is 0.3% ahead of the NVIDIA RTX 4000 SFF Ada Generation, 1.3% behind the AMD Radeon PRO W7700, 2.6% ahead of the NVIDIA Tesla V100 SXM2 16 GB, and 3% ahead of the NVIDIA RTX A5500 Mobile.

Q: What is the memory bandwidth difference between the two?

A: The MI350X provides 8.19 TB/s of bandwidth, and the GB10 provides 273.2 GB/s. The MI350X bandwidth is approximately 30 times higher.

Q: Which device supports display output?

A: The GB10 has one HDMI output. The MI350X has no display outputs.

Q: What are the power requirements for each?

A: The MI350X has a TDP of 1000 W and a suggested power supply of 1400 W. The GB10 has a TDP of 140 W and a suggested power supply of 300 W.

Q: What process nodes do the two devices use?

A: The MI350X uses a 3 nm TSMC process. The GB10 uses a 5 nm TSMC process.

Q: What is the release date for each device?

A: The MI350X was released on 2025-06-11. The GB10 was released on 2025-10-14.