AMD Instinct MI350P vs NVIDIA RTX 6000D Comparison

Head-to-Head Benchmarks

The recorded data does not include any shared benchmark runs between the AMD Instinct MI350P and the NVIDIA RTX 6000D. The head-to-head comparison table is empty, and the win tally shows zero victories for either part. This means a direct, same-test numerical comparison cannot be constructed from the database. What the database does provide is a set of absolute scores for the RTX 6000D and a percentile placement for each card, which allows for a partial picture.

The RTX 6000D has two recorded benchmark results. In 3DMark Steel Nomad DX12, it scores 3,522. In Geekbench OpenCL, it scores 388,405. These are standalone figures, not deltas against the MI350P. The MI350P, by contrast, has no benchmark entries at all in the database. Its average benchmark score is listed as 0, and its percentile versus all GPUs is 50. The RTX 6000D sits at the 98th percentile, and its average benchmark score across the two recorded tests is 195,964.

The nearest rival data for the RTX 6000D gives context that the MI350P lacks. The RTX 6000D runs 0.8% ahead of the NVIDIA Tesla V100S PCIe 32 GB, which averages 194,415. It is 4.7% ahead of the NVIDIA A100 SXM4 40 GB, which averages 187,147. It trails the NVIDIA A100 PCIe 80 GB by 5.4%, with that rival averaging 207,124. The RTX 6000D also sits 6.1% ahead of the NVIDIA RTX 5000 Ada Generation, which averages 184,664. These margins show the RTX 6000D clustering tightly with high-end NVIDIA accelerators, within roughly 6% either direction.

Because the MI350P has no benchmark scores, the database cannot substantiate any performance claim for it relative to the RTX 6000D. The percentile gap is large, 50 versus 98, but without shared tests the percentile alone does not translate into a measured performance difference. The analysis must therefore proceed on architectural and specification grounds, where the two cards diverge sharply.

Architecture Differences

The MI350P uses AMD's CDNA 4.0 architecture, built on a 3 nm process at TSMC. The chip is labeled MI350 128CU and packs 73,000 million transistors on a 1190 mm² die. Transistor density is 61.3 million per square millimeter. This is a compute-oriented design with no display outputs and no graphics API support. The RTX 6000D uses NVIDIA's Blackwell 2.0 architecture on a 5 nm process, also at TSMC. Its GB202 chip contains 92,200 million transistors on a 750 mm² die, for a density of 122.9 million per square millimeter. The RTX 6000D carries four DisplayPort 2.1b outputs and supports DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4. The MI350P lists N/A for DirectX, OpenGL, and Vulkan, so it is not a graphics card in the conventional sense.

The compute resources are configured very differently. The MI350P has 8,192 shading units and 512 texture mapping units, with no ROPs listed. The RTX 6000D has 19,968 shading units, 624 TMUs, and 192 ROPs. The RTX 6000D also has 156 ray tracing cores and 624 tensor cores, while the MI350P lists no RT or tensor core counts. Pixel rate for the MI350P is 0 MPixel/s, reflecting its lack of raster output hardware. The RTX 6000D delivers 466.6 GPixel/s. Texture rate favors the RTX 6000D at 1,516.3 GTexel/s versus 1,126.4 GTexel/s for the MI350P. FP32 throughput is 97.04 TFLOPS for the RTX 6000D and 36.04 TFLOPS for the MI350P. Both list FP16 at the same figure as FP32, a 1:1 ratio.

Memory architecture is fundamentally different. The MI350P uses 144 GB of HBM3e on an 8192-bit bus, delivering 8.19 TB/s of bandwidth. The RTX 6000D uses 84 GB of GDDR7 on a 448-bit bus, delivering 1.40 TB/s. Clock behavior differs: the MI350P has a 1000 MHz base and 2200 MHz boost, with memory at 2000 MHz operating at 8 Gbps effective. The RTX 6000D has a 1992 MHz base and 2430 MHz boost, with memory at 1560 MHz operating at 25 Gbps effective. The MI350P has a much larger memory pool and far higher bandwidth, while the RTX 6000D has higher clock speeds, more shading units, and higher FP32 throughput.

Both cards draw 600 W, use a dual-slot cooler, and require a single 16-pin power connector. Both suggest a 1000 W power supply. Both use PCIe 5.0 x16. Physical dimensions differ: the MI350P is 267 mm long, 111 mm tall, and 40 mm wide. The RTX 6000D is 304 mm long, 137 mm tall, and 40 mm wide. The RTX 6000D is the larger board.

Where Each One Wins

The RTX 6000D wins on raw compute throughput and graphics capability. Its FP32 figure of 97.04 TFLOPS is roughly 2.7 times the MI350P's 36.04 TFLOPS. Its texture rate is 34.6% higher at 1,516.3 GTexel/s versus 1,126.4 GTexel/s. It has 19,968 shading units, more than double the MI350P's 8,192. The RTX 6000D has ray tracing cores, tensor cores, and ROPs, none of which are listed for the MI350P. It supports a full graphics API stack, including DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4, and it provides four DisplayPort 2.1b outputs. The MI350P has no display outputs and no graphics API support. The RTX 6000D also has a much smaller die, 750 mm² versus 1190 mm², and a higher transistor density of 122.9 million per square millimeter versus 61.3 million.

The MI350P wins on memory capacity and bandwidth. Its 144 GB of HBM3e is 71.4% more than the RTX 6000D's 84 GB. Its 8.19 TB/s bandwidth is 5.85 times the RTX 6000D's 1.40 TB/s. The MI350P's 8192-bit bus dwarfs the RTX 6000D's 448-bit bus. This points to workloads dominated by large datasets and memory-bound operations, where the MI350P can move far more data per second and hold far larger working sets. The MI350P also uses a newer process node at 3 nm versus 5 nm, and it is a shorter card at 267 mm versus 304 mm, which may matter in dense server chassis.

The release timing is notable. The RTX 6000D has a recorded release date of July 13, 2025, and its production status is Active. The MI350P has a release date of May 6, 2026, and no production status is recorded. The MI350P is a newer product by roughly ten months. The RTX 6000D has a predecessor listed as Workstation Ada; the MI350P's predecessor is Radeon Instinct. Neither has a successor listed.

Specification Differences

The two cards differ across nearly every major specification category.

Process node: MI350P at 3 nm, RTX 6000D at 5 nm. Both use TSMC.

Transistors: MI350P at 73,000 million, RTX 6000D at 92,200 million. The RTX 6000D has 26.3% more transistors.

Die size: MI350P at 1190 mm², RTX 6000D at 750 mm². The MI350P has a 58.7% larger die.

Transistor density: MI350P at 61.3 million per mm², RTX 6000D at 122.9 million per mm².

Base clock: MI350P at 1000 MHz, RTX 6000D at 1992 MHz.

Boost clock: MI350P at 2200 MHz, RTX 6000D at 2430 MHz.

Memory clock: MI350P at 2000 MHz, 8 Gbps effective; RTX 6000D at 1560 MHz, 25 Gbps effective.

Memory size: MI350P at 144 GB, RTX 6000D at 84 GB.

Memory type: MI350P at HBM3e, RTX 6000D at GDDR7.

Memory bus: MI350P at 8192 bit, RTX 6000D at 448 bit.

Memory bandwidth: MI350P at 8.19 TB/s, RTX 6000D at 1.40 TB/s.

Shading units: MI350P at 8,192, RTX 6000D at 19,968.

TMUs: MI350P at 512, RTX 6000D at 624.

ROPs: MI350P at 0, RTX 6000D at 192.

RT cores: none listed for MI350P, 156 for RTX 6000D.

Tensor cores: none listed for MI350P, 624 for RTX 6000D.

Pixel rate: MI350P at 0 MPixel/s, RTX 6000D at 466.6 GPixel/s.

Texture rate: MI350P at 1,126.4 GTexel/s, RTX 6000D at 1,516.3 GTexel/s.

FP32: MI350P at 36.04 TFLOPS, RTX 6000D at 97.04 TFLOPS.

FP16: MI350P at 36.04 TFLOPS (1:1), RTX 6000D at 97.04 TFLOPS (1:1).

TDP: both at 600 W.

Slot width: both dual-slot.

Power connector: both 1x 16-pin.

Suggested PSU: both 1000 W.

Bus interface: both PCIe 5.0 x16.

Display outputs: MI350P has none, RTX 6000D has 4x DisplayPort 2.1b.

API support: MI350P has N/A for DirectX, OpenGL, and Vulkan; RTX 6000D supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4.

Dimensions: MI350P is 267 mm long, 111 mm tall, 40 mm wide; RTX 6000D is 304 mm long, 137 mm tall, 40 mm wide.

Production status: MI350P has none recorded, RTX 6000D is Active.

Release date: MI350P on May 6, 2026; RTX 6000D on July 13, 2025.

Predecessor: MI350P lists Radeon Instinct, RTX 6000D lists Workstation Ada.

Launch MSRP: the RTX 6000D is listed at 8,565 USD. The MI350P has no launch MSRP recorded.

FAQ

Q: Which card has higher FP32 compute throughput?

A: The NVIDIA RTX 6000D. It delivers 97.04 TFLOPS, while the AMD Instinct MI350P delivers 36.04 TFLOPS.

Q: How much memory does each card have?

A: The AMD Instinct MI350P has 144 GB of HBM3e. The NVIDIA RTX 6000D has 84 GB of GDDR7.

Q: What is the memory bandwidth difference?

A: The MI350P provides 8.19 TB/s over an 8192-bit bus. The RTX 6000D provides 1.40 TB/s over a 448-bit bus.

Q: Does the MI350P support graphics APIs?

A: No. The MI350P lists N/A for DirectX, OpenGL, and Vulkan, and has no display outputs. The RTX 6000D supports DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4, and has four DisplayPort 2.1b outputs.

Q: How does the RTX 6000D compare to its nearest rivals?

A: The RTX 6000D is 0.8% ahead of the Tesla V100S PCIe 32 GB, 4.7% ahead of the A100 SXM4 40 GB, 6.1% ahead of the RTX 5000 Ada Generation, and 5.4% behind the A100 PCIe 80 GB.

Q: What are the power requirements for each card?

A: Both cards have a 600 W TDP, use a dual-slot cooler, require a single 16-pin power connector, and list a suggested PSU of 1000 W.