AMD Instinct MI350P vs NVIDIA GeForce RTX 4060 Comparison

Where Each One Wins

The recorded data splits these two accelerators into completely separate use cases. The AMD Instinct MI350P is a compute-oriented accelerator with no display outputs, no DirectX, OpenGL, or Vulkan support, and zero benchmark entries in the database. Its measured percentile against all GPUs sits at 50, with an average benchmark score of 0. This is a device built for data center workloads, not for rendering frames or running graphics APIs.

The NVIDIA GeForce RTX 4060, by contrast, is a fully featured consumer graphics card. It carries DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4 support, plus three display outputs. The database records ten benchmark scores for the RTX 4060, ranging from a PassMark G2D score of 1037 to a Geekbench OpenCL score of 95057. Its average benchmark score is 17639, and its percentile versus all GPUs is 61.

The MI350P wins where raw memory capacity and bandwidth matter. It offers 144 GB of HBM3e memory on an 8192-bit bus, delivering 8.19 TB/s of bandwidth. The RTX 4060 uses 8 GB of GDDR6 on a 128-bit bus with 272.0 GB/s. The MI350P also leads in raw shader throughput, texture rate, and FP32 compute, at 36.04 TFLOPS versus 15.11 TFLOPS. But none of that matters for a desktop user, because the MI350P cannot output video and has no graphics API support.

The RTX 4060 wins in every scenario that involves a monitor, a game, or a standard graphics benchmark. The database contains no comparable benchmarks for the MI350P, so the RTX 4060 is the only one of the two with measured performance data. For any task that requires DirectX, OpenGL, or Vulkan, the MI350P is simply not a candidate.

Architecture Differences

The two chips come from different design philosophies. The MI350P uses CDNA 4.0 architecture on a 3 nm TSMC process, with 73,000 million transistors on a 1190 mm² die. That works out to 61.3M transistors per mm². The RTX 4060 uses Ada Lovelace architecture on a 5 nm TSMC process, with 18,900 million transistors on a 159 mm² die, for a density of 118.9M per mm². The MI350P is a massive accelerator built around memory bandwidth and compute density. The RTX 4060 is a compact consumer chip with higher transistor density but far fewer total transistors.

The MI350P has 8192 shading units and 512 texture mapping units, but its pixel rate is recorded as 0 MPixel/s and it has 0 ROPs. It has no ray tracing cores and no tensor cores listed. Its FP16 performance matches its FP32 at 36.04 TFLOPS (1:1). The RTX 4060 has 3072 shading units, 96 TMUs, 48 ROPs, 24 ray tracing cores, and 96 tensor cores. Its FP16 and FP32 are both 15.11 TFLOPS (1:1).

Memory architecture separates the two completely. The MI350P uses HBM3e, with a 2000 MHz base memory clock and 8 Gbps effective, across an 8192-bit interface. The RTX 4060 uses GDDR6 at 2125 MHz with 17 Gbps effective, on a 128-bit interface. The MI350P's memory bandwidth of 8.19 TB/s is roughly 30 times the RTX 4060's 272.0 GB/s.

The MI350P runs at a base clock of 1000 MHz and a boost of 2200 MHz. The RTX 4060 runs at 1830 MHz base and 2460 MHz boost. The MI350P consumes 600 W with a suggested 1000 W PSU. The RTX 4060 consumes 115 W with a suggested 300 W PSU. The power connector differs too: 1x 16-pin on the MI350P, 1x 12-pin on the RTX 4060.

The MI350P uses PCIe 5.0 x16. The RTX 4060 uses PCIe 4.0 x8. The MI350P has no display outputs. The RTX 4060 has 1x HDMI 2.1 and 3x DisplayPort 1.4a. The MI350P's API support is listed as N/A across DirectX, OpenGL, and Vulkan. The RTX 4060 supports all three.

FAQ

Q: Which card can play games?

A: Only the RTX 4060. It supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4, and has display outputs. The MI350P has no display outputs and lists N/A for all graphics APIs.

Q: How do their memory subsystems compare?

A: The MI350P has 144 GB of HBM3e on an 8192-bit bus with 8.19 TB/s bandwidth. The RTX 4060 has 8 GB of GDDR6 on a 128-bit bus with 272.0 GB/s bandwidth.

Q: Which one has more compute throughput?

A: The MI350P. Its FP32 performance is 36.04 TFLOPS, its texture rate is 1,126.4 GTexel/s, and it has 8192 shading units. The RTX 4060 delivers 15.11 TFLOPS FP32, 236.2 GTexel/s, and 3072 shading units.

Q: What is the power requirement difference?

A: The MI350P has a 600 W TDP and a suggested 1000 W PSU. The RTX 4060 has a 115 W TDP and a suggested 300 W PSU.

Q: Are there benchmark scores for the MI350P in the database?

A: No. The MI350P has an empty benchmark list, an average score of 0, and no nearest rivals. The RTX 4060 has ten recorded benchmark scores with an average of 17639.

Q: What is the release timeline for each?

A: The MI350P has a release date of 2026-05-06. The RTX 4060 was released on 2023-05-17 and is marked end-of-life, with the GeForce 50 as its successor.

Specification Differences

The two devices differ in nearly every recorded specification. The MI350P uses a 3 nm node, the RTX 4060 a 5 nm node. Transistor count is 73,000 million versus 18,900 million. Die size is 1190 mm² versus 159 mm². Transistor density favors the RTX 4060 at 118.9M per mm² against 61.3M per mm².

Base clocks are 1000 MHz for the MI350P and 1830 MHz for the RTX 4060. Boost clocks are 2200 MHz and 2460 MHz. Memory clocks are 2000 MHz (8 Gbps effective) versus 2125 MHz (17 Gbps effective). Memory size is 144 GB versus 8 GB. Memory type is HBM3e versus GDDR6. Bus width is 8192 bit versus 128 bit. Bandwidth is 8.19 TB/s versus 272.0 GB/s.

Shader counts are 8192 versus 3072. TMUs are 512 versus 96. ROPs are 0 versus 48. The RTX 4060 has 24 ray tracing cores and 96 tensor cores; the MI350P lists none. Pixel rate is 0 MPixel/s versus 118.1 GPixel/s. Texture rate is 1,126.4 GTexel/s versus 236.2 GTexel/s. FP32 is 36.04 TFLOPS versus 15.11 TFLOPS. FP16 is 36.04 TFLOPS (1:1) for both, but at different magnitudes.

TDP is 600 W versus 115 W. Power connectors are 1x 16-pin versus 1x 12-pin. Suggested PSU is 1000 W versus 300 W. Bus interface is PCIe 5.0 x16 versus PCIe 4.0 x8. The MI350P has no display outputs; the RTX 4060 has 1x HDMI 2.1 and 3x DisplayPort 1.4a. The MI350P lists N/A for DirectX, OpenGL, and Vulkan. The RTX 4060 lists 12 Ultimate (12_2), 4.6, and 1.4 respectively. The MI350P is 267 mm long, the RTX 4060 is 240 mm. Both are 111 mm high and 40 mm wide. The RTX 4060 has a launch MSRP of 299 USD.

Head-to-Head Benchmarks

The database contains no head-to-head benchmark comparisons between the MI350P and the RTX 4060. The MI350P has no benchmark entries at all, no average score, and no nearest rivals. The RTX 4060 carries the full set of recorded measurements.

The RTX 4060's highest recorded scores come from Geekbench OpenCL at 95057 and Geekbench Vulkan at 48643. Its PassMark G3D score is 19545, and its PassMark GPU Compute score is 9213. In DirectX tests, it scores 103 in PassMark DirectX 10, 175 in DirectX 11, 76 in DirectX 12, and 236 in DirectX 9. Its PassMark G2D score is 1037. Its 3DMark Steel Nomad DX12 score is 2302.

Against its nearest rivals, the RTX 4060 sits within a tight band. The AMD Radeon HD 7790 scores 17666, which is 0.2% above the RTX 4060. The AMD Radeon 780M scores 17588, 0.3% below. The AMD Radeon Pro 560 scores 17551, 0.5% below. The AMD Radeon Pro 460 scores 17509, 0.7% below. The RTX 4060's average of 17639 places it roughly in the middle of this group, essentially tied with the HD 7790 and slightly ahead of the integrated and mobile parts.

The MI350P's 36.04 TFLOPS FP32 is more than double the RTX 4060's 15.11 TFLOPS, but there are no compute benchmarks in the database to translate that into a measured score. The MI350P's 50th percentile with a zero average score reflects its absence from the benchmark suite, not a measured performance level.

The Verdict

The data describes two products with no functional overlap. The MI350P is a 600 W accelerator with 144 GB of HBM3e, 8.19 TB/s of bandwidth, and 36.04 TFLOPS FP32, but it cannot drive a display and supports no consumer graphics APIs. Its release date of 2026-05-06 places it as a future data center part. The RTX 4060 is an end-of-life consumer GPU from 2023, with full graphics API support, display outputs, and a complete set of recorded benchmark scores.

Anyone building a system for DirectX, OpenGL, or Vulkan workloads should use the RTX 4060. It is the only one of the two with any measured graphics performance, and its nearest rival comparisons show it performing in line with cards like the AMD Radeon HD 7790 and AMD Radeon 780M. Its 115 W TDP and 300 W suggested PSU make it compatible with standard desktop builds.

Anyone working on compute tasks that require massive memory capacity and bandwidth should look at the MI350P. Its 144 GB HBM3e pool and 8.19 TB/s bandwidth are in a different class from the RTX 4060's 8 GB and 272.0 GB/s. But the database contains no benchmark scores for the MI350P, so its measured compute performance cannot be verified here. The absence of display outputs and API support means it is solely a server or workstation accelerator.

The choice comes down to workload. The RTX 4060 delivers measured graphics performance and broad software compatibility. The MI350P offers extreme memory and compute specifications with no recorded benchmarks. The data supports the RTX 4060 for any graphics task and the MI350P only for scenarios where its memory capacity and bandwidth are the deciding factors.