AMD Instinct MI350P vs AMD Radeon PRO W7500 Comparison

AMD Instinct MI350P and AMD Radeon PRO W7500 are both AMD workstation and data center GPUs, but they are engineered for entirely different workloads. The MI350P is a data center accelerator built on CDNA 4.0 architecture, while the W7500 is a professional graphics card based on RDNA 3.0. This analysis compares their recorded data across compute, memory, and feature sets.

Head-to-Head Benchmarks

The database contains benchmark results for the AMD Radeon PRO W7500, while the AMD Instinct MI350P has no recorded benchmark scores. This absence is notable, as the MI350P is designed for compute workloads rather than rendering, so standard graphics benchmarks may not reflect its intended performance. The W7500 shows an average benchmark score of 16415, placing it in the 59th percentile of all GPUs. Its nearest rivals include the NVIDIA RTX PRO 6000 Blackwell at an average score of 16408, with a delta of 0 percent, and the AMD Radeon RX 5700 XT at 16361, which is 0.3 percent behind. The AMD Radeon Pro 5600M scores 16351, trailing by 0.4 percent, while the NVIDIA GeForce RTX 5090 D V2 leads with a score of 16504, a -0.5 percent delta from the W7500.

The W7500 delivers specific performance figures across several tests. In Geekbench OpenCL, it scores 58213, and in Geekbench Vulkan, it scores 68634. Passmark results show a G3D score of 13368, a GPU compute score of 5910, and a G2D score of 1174. Legacy DirectX tests record scores of 200 for DirectX 9, 125 for DirectX 11, 65 for DirectX 10, and 46 for DirectX 12. These numbers indicate a capable workstation card for graphics and compute tasks, though the MI350P cannot be directly compared due to missing data. The data shows the W7500 sits in a competitive position against its closest rivals, with deltas under 1 percent in all cases.

Architecture Differences

The AMD Instinct MI350P uses the CDNA 4.0 architecture, specifically designed for compute and AI workloads, whereas the AMD Radeon PRO W7500 uses RDNA 3.0, optimized for graphics and rendering. The MI350P is built on a 3 nm process node from TSMC, housing 73,000 million transistors on a 1190 mm² die, yielding a transistor density of 61.3M per mm². The W7500 uses a 6 nm process node, also from TSMC, with 13,300 million transistors on a 204 mm² die, giving a density of 65.2M per mm². The MI350P’s die is substantially larger, reflecting its focus on massive parallel compute.

The MI350P features 8192 shading units, 512 texture mapping units, and 0 ROPs, which confirms it is not a rasterization-focused part. Its pixel rate is 0 MPixel/s, and its texture rate is 1,126.4 GTexel/s. In contrast, the W7500 has 1792 shading units, 112 TMUs, and 64 ROPs, with a pixel rate of 108.8 GPixel/s and a texture rate of 190.4 GTexel/s. The W7500 also includes 28 ray tracing cores, while the MI350P has none listed. Neither card specifies tensor cores, though the MI350P’s CDNA architecture is designed for matrix operations.

Memory configurations diverge sharply. The MI350P carries 144 GB of HBM3e memory on an 8192-bit bus, delivering 8.19 TB/s of bandwidth. The W7500 has 8 GB of GDDR6 memory on a 128-bit bus, with 256.0 GB/s of bandwidth. The MI350P’s memory bandwidth is far higher, suited to large data sets, while the W7500’s smaller pool still supports professional graphics workloads. The MI350P’s memory clock is listed as 2000 MHz with 8 Gbps effective, while the W7500 also runs at 2000 MHz but with 16 Gbps effective, indicating faster per-pin transfer on the consumer-oriented part.

Where Each One Wins

The data indicates a clear split based on workload type. The AMD Instinct MI350P wins in raw compute density and memory capacity. Its 144 GB of HBM3e memory and 8.19 TB/s bandwidth are designed for large model training and inference, tasks that require holding enormous datasets on-card. The 8192 shading units and 1,126.4 GTexel/s texture rate show a focus on throughput, not pixel output, as seen in the 0 MPixel/s pixel rate. The MI350P also uses a 3 nm process, which allows for a higher transistor count despite the massive die size, and it supports PCIe 5.0 x16 for faster host communication.

The AMD Radeon PRO W7500 wins in graphics-oriented workloads. Its 64 ROPs and 108.8 GPixel/s pixel rate enable rasterization, and the 28 ray tracing cores add hardware acceleration for ray-traced rendering. The W7500 supports DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4, whereas the MI350P has no API support listed, meaning it cannot drive displays or run graphics applications. The W7500’s 4x DisplayPort 2.1 outputs make it a viable option for multi-monitor professional setups. Its 70 W TDP and single-slot design also make it easier to integrate into workstations, while the MI350P’s 600 W TDP and dual-slot footprint require dedicated data center power and cooling.

FAQ

Q: Which GPU has more memory bandwidth?

A: The AMD Instinct MI350P has 8.19 TB/s of bandwidth from 144 GB of HBM3e memory on an 8192-bit bus. The AMD Radeon PRO W7500 has 256.0 GB/s from 8 GB of GDDR6 on a 128-bit bus.

Q: Can the AMD Instinct MI350P output video to displays?

A: No. The MI350P has no display outputs listed and supports no graphics APIs (DirectX, OpenGL, Vulkan are all N/A), making it a compute-only accelerator. The W7500 has 4x DisplayPort 2.1 outputs and full API support.

Q: What is the transistor density of each chip?

A: The MI350P has a transistor density of 61.3M per mm² with 73,000 million transistors on a 1190 mm² die. The W7500 has a density of 65.2M per mm² with 13,300 million transistors on a 204 mm² die.

Q: How does the W7500 compare to its nearest rival, the NVIDIA RTX PRO 6000 Blackwell?

A: The W7500 has an average benchmark score of 16415, while the RTX PRO 6000 Blackwell scores 16408. The delta is 0 percent, indicating essentially identical average performance in recorded tests.

Q: Does the MI350P have ray tracing cores?

A: No. The MI350P lists no ray tracing cores, while the W7500 has 28. The MI350P is built for compute, not graphics rendering.

Q: What are the power requirements for each card?

A: The MI350P has a TDP of 600 W and requires a 1000 W suggested PSU with a 1x 16-pin power connector. The W7500 has a TDP of 70 W, a 250 W suggested PSU, and requires no power connectors.

Specification Differences

| Specification | AMD Instinct MI350P | AMD Radeon PRO W7500 |

|---------------|---------------------|----------------------|

| Architecture | CDNA 4.0 | RDNA 3.0 |

| Process Node | 3 nm | 6 nm |

| Transistors | 73,000 million | 13,300 million |

| Die Size | 1190 mm² | 204 mm² |

| Base Clock | 1000 MHz | 1500 MHz |

| Boost Clock | 2200 MHz | 1700 MHz |

| Memory Size | 144 GB | 8 GB |

| Memory Type | HBM3e | GDDR6 |

| Memory Bus Width | 8192 bit | 128 bit |

| Memory Bandwidth | 8.19 TB/s | 256.0 GB/s |

| Shading Units | 8192 | 1792 |

| TMUs | 512 | 112 |

| ROPs | 0 | 64 |

| Ray Tracing Cores | None | 28 |

| Pixel Rate | 0 MPixel/s | 108.8 GPixel/s |

| Texture Rate | 1,126.4 GTexel/s | 190.4 GTexel/s |

| FP32 Performance | 36.04 TFLOPS | 12.19 TFLOPS |

| FP16 Performance | 36.04 TFLOPS (1:1) | 24.37 TFLOPS (2:1) |

| TDP | 600 W | 70 W |

| Slot Width | Dual-slot | Single-slot |

| Power Connectors | 1x 16-pin | None |

| Suggested PSU | 1000 W | 250 W |

| Bus Interface | PCIe 5.0 x16 | PCIe 4.0 x8 |

| Display Outputs | No outputs | 4x DisplayPort 2.1 |

| DirectX Support | N/A | 12 Ultimate (12_2) |

| OpenGL Support | N/A | 4.6 |

| Vulkan Support | N/A | 1.4 |

| Release Date | 2026-05-06 | 2023-08-02 |

| Launch MSRP | None | 429 USD |

The Verdict

The recorded data shows two distinct tools. The AMD Instinct MI350P is a data center compute accelerator, evident from its 144 GB HBM3e memory, 8.19 TB/s bandwidth, 8192 shading units, and 36.04 TFLOPS FP32 performance. It has no display outputs and no graphics API support, confirming it is not for rendering. Its 600 W TDP and dual-slot size place it in server racks, not desktop workstations. The MI350P’s 3 nm process and 73,000 million transistors indicate a focus on massive parallel compute, and its 2026 release date suggests it targets future AI and HPC workloads.

The AMD Radeon PRO W7500 is a professional graphics card, with 64 ROPs, 28 ray tracing cores, 4x DisplayPort 2.1 outputs, and full DirectX, OpenGL, and Vulkan support. Its 12.19 TFLOPS FP32 and 24.37 TFLOPS FP16 performance are lower than the MI350P, but its 70 W TDP and single-slot design make it suitable for standard workstations. The W7500’s average benchmark score of 16415 and 59th percentile ranking show it competes directly with cards like the RTX PRO 6000 Blackwell and RX 5700 XT, with deltas under 1 percent. The MI350P lacks benchmark data, so direct performance comparison is impossible, but the architectural differences make the choice clear: the MI350P for compute-heavy data center tasks, the W7500 for graphics and rendering in professional environments.