AMD Instinct MI350P vs AMD Radeon 680M Comparison

Architecture Differences

The AMD Instinct MI350P and AMD Radeon 680M represent opposite ends of AMD's GPU design spectrum. The MI350P is built on the CDNA 4.0 architecture, a compute-optimized design intended for data center acceleration, while the Radeon 680M uses the RDNA 2.0 architecture, a graphics-focused design for integrated mobile solutions. This fundamental split determines nearly every other difference between the two parts.

The MI350P uses a 3 nm process from TSMC, while the Radeon 680M is fabricated on a 6 nm node, also from TSMC. The transistor counts differ enormously: the MI350P packs 73,000 million transistors across a 1190 mm² die, while the Radeon 680M integrates 13,100 million transistors on a 208 mm² die. Interestingly, the transistor density is similar, 61.3M per mm² for the MI350P versus 63.0M per mm² for the Radeon 680M. The MI350P's massive die size reflects its HBM3e memory stack integration, whereas the Radeon 680M is a compact IGP that shares system memory.

The MI350P belongs to the Instinct (MIx) generation and carries the chip identifier "MI350 128CU". The Radeon 680M uses the "Rembrandt+" chip and is classified under Navi II IGP (Rembrandt Mobile). Their predecessors also differ: the MI350P follows the Radeon Instinct line, while the Radeon 680M replaces Vega II IGP and has a successor in Navi III IGP.

The MI350P provides no display outputs and no graphics API support, with DirectX, OpenGL, and Vulkan all listed as N/A. The Radeon 680M, by contrast, supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4. This confirms the MI350P is not a graphics card in the conventional sense; it is a pure compute accelerator. The Radeon 680M also includes 12 ray tracing cores, while the MI350P lists none. Both parts have no dedicated tensor cores in the recorded data.

The MI350P has 8,192 shading units and 512 texture mapping units, but 0 ROPs. Its pixel rate is recorded as 0 MPixel/s. The Radeon 680M has 768 shading units, 48 TMUs, and 32 ROPs, with a pixel rate of 70.40 GPixel/s. The texture rates are 1,126.4 GTexel/s for the MI350P versus 105.6 GTexel/s for the Radeon 680M.

Specification Differences

Clock behavior separates the two parts. The MI350P runs a base clock of 1000 MHz and boosts to 2200 MHz. The Radeon 680M has a much higher base clock of 2000 MHz but matches the same 2200 MHz boost. Memory clocks differ sharply: the MI350P uses 2000 MHz with 8 Gbps effective, while the Radeon 680M relies on System Shared memory with System Dependent bandwidth.

Memory capacity and type are the largest specification gaps. The MI350P offers 144 GB of HBM3e on an 8192-bit bus, delivering 8.19 TB/s of bandwidth. The Radeon 680M uses System Shared memory with no dedicated capacity, bus width, or bandwidth figures; all are marked System Shared or System Dependent. This is a fundamental architectural difference: one card carries its own high-bandwidth memory, the other borrows from the host system.

Compute throughput diverges substantially. The MI350P delivers 36.04 TFLOPS FP32 and the same 36.04 TFLOPS FP16 at a 1:1 ratio. The Radeon 680M provides 3.379 TFLOPS FP32 and 6.758 TFLOPS FP16 at a 2:1 ratio. The MI350P's FP16 performance is not accelerated relative to FP32, while the Radeon 680M doubles its throughput in FP16.

Power and physical requirements differ by an order of magnitude. The MI350P consumes 600 W TDP, requires a 1000 W suggested PSU, uses a single 16-pin power connector, and occupies a dual-slot form factor with dimensions of 267 mm length, 111 mm height, and 40 mm width. The Radeon 680M consumes only 50 W TDP, has no power connectors, and is an IGP with no independent dimensions. The MI350P connects via PCIe 5.0 x16; the Radeon 680M uses PCIe 4.0 x8.

The MI350P has no launch MSRP recorded and no production status listed. The Radeon 680M is marked as Active in production. Release dates also differ: the MI350P is dated 2026-05-06, while the Radeon 680M is dated 2023-01-02.

The Verdict

The data indicates these are not competing products. The MI350P is a 600 W, 144 GB HBM3e compute accelerator with no display outputs and no graphics API support. The Radeon 680M is a 50 W integrated GPU for mobile devices, supporting DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4, with active production status. Any user requiring graphics output, ray tracing, or low power consumption must choose the Radeon 680M. Any workload demanding 144 GB of HBM3e memory, 8.19 TB/s bandwidth, or 36.04 TFLOPS FP32 points to the MI350P.

The Radeon 680M holds an average benchmark score of 15,270 and sits at the 57th percentile among all GPUs. Its nearest rivals in the database are the NVIDIA GeForce GTX 580 at 15,283 (0.1% faster), the NVIDIA GeForce RTX 2060 at 15,290 (0.1% faster), the NVIDIA GeForce RTX 3050 OEM at 15,199 (0.5% slower), and the AMD Radeon RX 7600 at 15,171 (0.7% slower). These delta values are small, placing the 680M in a tight competitive cluster around the 15,200 to 15,300 score range.

The MI350P has no recorded benchmarks, no average score, and no nearest rivals. Its percentile versus all GPUs is listed at 50, which is a neutral placeholder rather than a meaningful ranking. Without benchmark data, direct performance comparison is impossible.

For a system builder seeking a mobile integrated GPU with modern graphics API support, the Radeon 680M is the only viable choice between the two. For a data center operator needing massive memory bandwidth and FP32 compute, the MI350P is the clear selection. The Radeon 680M's active production status and its position in a competitive benchmark cluster give it a practical edge in availability and measured performance. The MI350P's lack of any benchmark entries means its real-world standing remains unquantified in this database.

Head-to-Head Benchmarks

The head-to-head benchmark list between these two parts is empty, and the wins counter shows 0 for both sides. This means no direct comparison tests have been recorded in the database. However, the Radeon 680M has standalone benchmark results that provide context for its performance tier.

In 3DMark Steel Nomad DX12, the Radeon 680M scores 378. This is a low result, consistent with an integrated GPU. In Geekbench OpenCL, it scores 23,468, and in Geekbench Vulkan, it scores 21,965. The OpenCL score is slightly higher than the Vulkan score, a difference of roughly 6.8%. The average benchmark score across all recorded tests is 15,270.

The Radeon 680M's nearest rivals show how tightly grouped this performance segment is. The NVIDIA GeForce GTX 580 scores 15,283, which is 0.1% higher than the 680M's average. The NVIDIA GeForce RTX 2060 scores 15,290, also 0.1% higher. The NVIDIA GeForce RTX 3050 OEM scores 15,199, which is 0.5% lower. The AMD Radeon RX 7600 scores 15,171, which is 0.7% lower. These deltas are all within 1%, indicating that the 680M performs essentially at parity with these discrete GPUs in aggregate benchmark terms, despite being an integrated part.

The MI350P has no benchmark entries at all. Its average benchmark score is recorded as 0, and its percentile versus all GPUs is 50. The absence of data means the MI350P cannot be positioned relative to any other GPU in the database. The FP32 throughput of 36.04 TFLOPS is over ten times the Radeon 680M's 3.379 TFLOPS, but without benchmark scores, this raw specification cannot be translated into a measured performance delta.

The memory bandwidth difference is similarly stark: 8.19 TB/s for the MI350P versus System Dependent for the Radeon 680M. Texture rate favors the MI350P at 1,126.4 GTexel/s versus 105.6 GTexel/s. The MI350P's FP16 output is identical to its FP32 at 36.04 TFLOPS, while the Radeon 680M's FP16 is double its FP32 at 6.758 TFLOPS. These figures show the MI350P is a compute-oriented part, while the Radeon 680M retains the graphics-oriented FP16 acceleration typical of RDNA architectures.

The Radeon 680M's ray tracing cores, 12 in total, give it hardware RT capability that the MI350P lacks entirely. Its 32 ROPs enable a pixel rate of 70.40 GPixel/s, while the MI350P has 0 ROPs and a 0 MPixel/s pixel rate. The MI350P cannot rasterize graphics, which is consistent with its lack of display outputs.

FAQ

Q: Which GPU has higher FP32 compute throughput?

A: The AMD Instinct MI350P delivers 36.04 TFLOPS FP32, while the AMD Radeon 680M delivers 3.379 TFLOPS FP32. The MI350P is over ten times faster in this metric.

Q: Does the AMD Instinct MI350P support DirectX or Vulkan?

A: No. The MI350P lists DirectX, OpenGL, and Vulkan all as N/A. It has no display outputs. The Radeon 680M supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4.

Q: How does the Radeon 680M compare to the NVIDIA GeForce GTX 580 in average benchmark score?

A: The Radeon 680M has an average benchmark score of 15,270. The NVIDIA GeForce GTX 580 scores 15,283, which is 0.1% higher. The two are effectively tied in aggregate performance.

Q: What memory configuration does the MI350P use?

A: The MI350P uses 144 GB of HBM3e memory on an 8192-bit bus, delivering 8.19 TB/s of bandwidth. The Radeon 680M uses System Shared memory with System Dependent bandwidth.

Q: Is the Radeon 680M still in production?

A: Yes. The production status for the AMD Radeon 680M is listed as Active. The MI350P has no production status recorded.

Q: What is the power consumption difference between the two GPUs?

A: The MI350P has a TDP of 600 W and requires a 1000 W suggested PSU. The Radeon 680M has a TDP of 50 W and requires no power connectors.