AMD Instinct MI325X vs AMD Radeon RX 7650 GRE Comparison

FAQ

Q: What is the architectural generation of each GPU?

A: The AMD Instinct MI325X uses the CDNA 3.0 architecture on the Aqua Vanjaram chip, while the AMD Radeon RX 7650 GRE uses the RDNA 3.0 architecture on the Navi 33 chip. The MI325X belongs to the Instinct (MIx) generation, whereas the RX 7650 GRE belongs to the Navi III (RX 7000) generation.

Q: How do the memory subsystems compare?

A: The Instinct MI325X features 256 GB of HBM3e memory on an 8192-bit bus, delivering 6.14 TB/s of bandwidth. The Radeon RX 7650 GRE has 8 GB of GDDR6 on a 128-bit bus, providing 288.0 GB/s. The MI325X memory bandwidth is more than 21 times higher.

Q: What are the core counts and compute capabilities?

A: The MI325X has 19,456 shading units, 1,216 TMUs, and no ROPs, delivering 81.72 TFLOPS FP32 and 81.72 TFLOPS FP16 (1:1). The RX 7650 GRE has 2,048 shading units, 128 TMUs, and 64 ROPs, delivering 22.08 TFLOPS FP32 and 22.08 TFLOPS FP16 (1:1).

Q: What is the power requirement difference?

A: The Instinct MI325X has a TDP of 1000 W and requires a 1400 W suggested PSU, with no power connectors (OAM Module form factor). The Radeon RX 7650 GRE has a 170 W TDP, uses a single 8-pin connector, and requires a 450 W suggested PSU.

Q: Which GPU has display outputs?

A: The Radeon RX 7650 GRE provides 1x HDMI 2.1a and 3x DisplayPort 2.1 outputs. The Instinct MI325X has no display outputs, as it is designed as an OAM Module for compute workloads.

Q: How do the benchmark scores and percentiles compare?

A: The RX 7650 GRE has an average benchmark score of 42,723 and sits in the 83rd percentile among all GPUs. The MI325X has no recorded benchmark scores and sits in the 50th percentile. The RX 7650 GRE trails the NVIDIA GeForce RTX 4070 SUPER by 1.2% in average score.

Architecture Differences

The two AMD GPUs share a manufacturer but diverge sharply in design purpose. The Instinct MI325X is built on CDNA 3.0, AMD's compute-optimized architecture, fabricated on a 5 nm TSMC process with 153,000 million transistors packed into a 1017 mm² die. The Radeon RX 7650 GRE uses RDNA 3.0, a graphics-first architecture, on a 6 nm TSMC process with 13,300 million transistors on a 204 mm² die. The transistor density difference is substantial: 150.4M per mm² for the MI325X versus 65.2M per mm² for the RX 7650 GRE.

The MI325X has no ROPs, no ray tracing cores, and no display outputs, reflecting its role as a compute accelerator. It also lacks API support for DirectX, OpenGL, or Vulkan. The RX 7650 GRE, by contrast, includes 64 ROPs, 32 ray tracing cores, and full API support: DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4. The RX 7650 GRE has a production status of Active, while the MI325X has no recorded production status.

Clock behavior also separates the two. The MI325X runs at a 1000 MHz base and 2100 MHz boost, with memory at 1500 MHz (6 Gbps effective). The RX 7650 GRE operates at a 1720 MHz base, 2350 MHz game clock, and 2695 MHz boost, with memory at 2250 MHz (18 Gbps effective). The RX 7650 GRE uses a dual-slot form factor with a single 8-pin power connector, while the MI325X is an OAM Module with no power connectors.

The pixel rate tells the story plainly: the MI325X delivers 0 MPixel/s because it has no raster output units, while the RX 7650 GRE produces 172.5 GPixel/s. Texture rates differ as well: 2,553.6 GTexel/s for the MI325X against 345.0 GTexel/s for the RX 7650 GRE. The MI325X's texture rate is over seven times higher, but its lack of ROPs means it cannot drive displays or perform traditional graphics rasterization.

The Verdict

The data indicates that these two GPUs serve entirely different markets. The Instinct MI325X is a compute-focused accelerator with massive memory capacity, extreme bandwidth, and no graphics output. Its 256 GB HBM3e memory and 6.14 TB/s bandwidth target workloads that require holding large datasets close to the processor. The absence of ROPs and display outputs confirms it is not intended for interactive graphics.

The Radeon RX 7650 GRE is a conventional graphics card with 8 GB GDDR6, 64 ROPs, and 32 ray tracing cores. It supports all major graphics APIs and provides multiple display outputs. Its average benchmark score of 42,723 places it in the 83rd percentile, and it sits within 1.3% of the NVIDIA GeForce RTX 4070 SUPER, Quadro M6000 24 GB, RTX 5050 Mobile, and Quadro M6000 in the nearest rivals list.

For compute tasks requiring massive memory and bandwidth, the MI325X is the only choice between the two, given its 256 GB capacity and 8192-bit bus. For any graphics workload, display output, or gaming scenario, the RX 7650 GRE is the functional option, as the MI325X cannot render frames or connect to monitors. The benchmark database shows no head-to-head wins for either GPU, and the MI325X has no recorded benchmark scores, so direct performance comparison relies on architectural specifications rather than measured results.

Specification Differences

The two GPUs differ across nearly every recorded specification. The MI325X uses a 5 nm process with 153,000 million transistors on a 1017 mm² die; the RX 7650 GRE uses a 6 nm process with 13,300 million transistors on a 204 mm² die. Transistor density stands at 150.4M per mm² for the MI325X and 65.2M per mm² for the RX 7650 GRE.

Clock speeds diverge: the MI325X has a 1000 MHz base and 2100 MHz boost, while the RX 7650 GRE has a 1720 MHz base, 2350 MHz game clock, and 2695 MHz boost. Memory clocks are 1500 MHz (6 Gbps effective) versus 2250 MHz (18 Gbps effective). Memory size is 256 GB HBM3e versus 8 GB GDDR6, with bus widths of 8192 bit versus 128 bit, and bandwidth of 6.14 TB/s versus 288.0 GB/s.

Shading units number 19,456 versus 2,048; TMUs are 1,216 versus 128; ROPs are 0 versus 64. The RX 7650 GRE has 32 ray tracing cores; the MI325X has none. Pixel rates are 0 MPixel/s versus 172.5 GPixel/s, and texture rates are 2,553.6 GTexel/s versus 345.0 GTexel/s. FP32 compute is 81.72 TFLOPS versus 22.08 TFLOPS, with FP16 matching at 81.72 TFLOPS (1:1) versus 22.08 TFLOPS (1:1).

Power figures differ widely: TDP is 1000 W versus 170 W, and suggested PSU is 1400 W versus 450 W. The MI325X uses an OAM Module slot width with no power connectors; the RX 7650 GRE is dual-slot with a single 8-pin connector. Bus interfaces are PCIe 5.0 x16 versus PCIe 4.0 x8. Display outputs are none versus 1x HDMI 2.1a and 3x DisplayPort 2.1. The RX 7650 GRE measures 204 mm in length and 115 mm in height; the MI325X has no recorded dimensions. Release dates are 2024-10-09 for the MI325X and 2025-02-06 for the RX 7650 GRE. The launch MSRP for the RX 7650 GRE is 279 USD; the MI325X has no recorded launch MSRP.

Head-to-Head Benchmarks

The database contains no shared benchmark results between the two GPUs. The MI325X has an empty benchmark array, an average benchmark score of 0, and no nearest rivals recorded. The RX 7650 GRE has two benchmark entries: a 3DMark Steel Nomad DX12 score of 2,336 and a Geekbench OpenCL score of 83,109. Its average benchmark score is 42,723.

Comparing the available data, the RX 7650 GRE's nearest rivals show tight clustering. The NVIDIA GeForce RTX 4070 SUPER averages 43,223, which is 1.2% higher than the RX 7650 GRE. The NVIDIA Quadro M6000 24 GB averages 43,262, also 1.2% higher. The NVIDIA GeForce RTX 5050 Mobile averages 43,268, 1.3% higher, and the NVIDIA Quadro M6000 averages 43,301, 1.3% higher. The RX 7650 GRE trails all four rivals by margins between 1.2% and 1.3%, indicating performance parity within a narrow band.

For the MI325X, the absence of benchmark scores means the database records no measured performance against any rival. Its 50th percentile placement among all GPUs reflects the lack of benchmark data rather than a performance estimate. The architectural specifications indicate compute capability far exceeding the RX 7650 GRE in FP32 throughput (81.72 TFLOPS versus 22.08 TFLOPS) and texture rate (2,553.6 GTexel/s versus 345.0 GTexel/s), but the MI325X cannot perform graphics rendering tasks due to zero ROPs and no display outputs.

The wins tally shows both GPUs with zero wins in head-to-head comparisons, as no shared benchmarks exist. The RX 7650 GRE's recorded scores place it in the 83rd percentile among all GPUs, while the MI325X sits at the 50th percentile with no scores. The data confirms that the RX 7650 GRE is a measurable graphics product with competitive standing near the RTX 4070 SUPER, while the MI325X remains a compute accelerator outside the graphics benchmark ecosystem.