NVIDIA B300 vs NVIDIA RTX PRO 4500 Blackwell Server Comparison

NVIDIA B300 and NVIDIA RTX PRO 4500 Blackwell Server are both active server-class accelerators from NVIDIA, but they target vastly different workloads. The B300 uses the GB110 chip with Blackwell Ultra architecture, while the RTX PRO 4500 uses GB203 with Blackwell 2.0. Both are built on a 5 nm process at TSMC, share the PCIe 5.0 x16 interface, and have no display outputs. The data shows two products with distinct memory systems, compute profiles, and power envelopes.

FAQ

Q: What are the memory capacities of these two GPUs?

A: The NVIDIA B300 has 144 GB of HBM3e memory with a 4096-bit bus and 4.10 TB/s bandwidth. The RTX PRO 4500 has 32 GB of GDDR7 on a 256-bit bus with 800.3 GB/s bandwidth. The B300 offers 4.5 times the capacity and over 5 times the bandwidth.

Q: How do their thermal design power (TDP) figures compare?

A: The B300 is rated at 1400 W with a suggested PSU of 1800 W, and it is an SXM module. The RTX PRO 4500 is a single-slot card at 165 W with a suggested PSU of 450 W and a single 16-pin power connector. The B300 draws about 8.5 times the power of the RTX PRO 4500.

Q: What are the FP32 and FP16 compute capabilities?

A: The B300 delivers 76.99 TFLOPS FP32 and 1,231.8 TFLOPS FP16 (16:1 ratio). The RTX PRO 4500 provides 50.70 TFLOPS FP32 and 50.70 TFLOPS FP16 (1:1 ratio). The B300 is roughly 1.5 times faster in FP32 but over 24 times faster in FP16.

Q: Do these GPUs support DirectX, OpenGL, or Vulkan?

A: The RTX PRO 4500 explicitly supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4. The B300 lists no API support in the database, consistent with its server-focused design without display outputs.

Q: What are the physical dimensions of the RTX PRO 4500?

A: The RTX PRO 4500 measures 267 mm in length, 111 mm in height, and 40 mm in width. The B300 has no listed dimensions, as it is an SXM module rather than a PCIe card.

Q: When were these products released?

A: The B300 has a release date of September 10, 2025. The RTX PRO 4500 has a release date of March 16, 2026. Both are currently marked as Active in production status.

Architecture Differences

The B300 uses the GB110 chip, built on the Blackwell Ultra architecture. The RTX PRO 4500 uses the GB203 chip, built on the Blackwell 2.0 architecture. Both are manufactured on a 5 nm process at TSMC, but the transistor counts differ sharply: the B300 integrates 104,000 million transistors, while the RTX PRO 4500 has 45,600 million. The RTX PRO 4500 has a die size of 378 mm² and a transistor density of 120.6M per mm²; the B300 has no die size listed.

The B300’s memory subsystem is built around HBM3e with 144 GB capacity and a 4096-bit bus, delivering 4.10 TB/s bandwidth. The RTX PRO 4500 uses GDDR7 with 32 GB capacity on a 256-bit bus, providing 800.3 GB/s bandwidth. This reflects different design goals: the B300 prioritizes massive memory throughput for large models, while the RTX PRO 4500 balances capacity with lower power consumption.

Compute resources also differ. The B300 has 18,944 shading units, 592 TMUs, and 24 ROPs. The RTX PRO 4500 has 10,496 shading units, 328 TMUs, and 112 ROPs. The B300 has 592 tensor cores, and the RTX PRO 4500 has 328 tensor cores. The RTX PRO 4500 includes 82 ray tracing cores, while the B300 has no RT core count listed. The B300’s ROP count is notably low at 24, which impacts its pixel rate of 48.77 GPixel/s. The RTX PRO 4500 has a pixel rate of 270.5 GPixel/s, over 5.5 times higher.

Clock behavior diverges significantly. The B300 has a base clock of 1665 MHz and a boost clock of 2032 MHz. The RTX PRO 4500 has a base clock of 1215 MHz and a boost clock of 2415 MHz. The RTX PRO 4500 boosts higher, but the B300 starts from a higher base. Memory clocks also differ: the B300 runs at 2000 MHz with 8 Gbps effective, while the RTX PRO 4500 runs at 1563 MHz with 25 Gbps effective. The B300’s wider bus compensates for its lower per-pin speed.

Head-to-Head Benchmarks

The database shows no recorded head-to-head benchmark entries, and both products have an average benchmark score of zero. The percentile versus all GPUs is 50 for both, indicating a midpoint ranking in the absence of measured performance data. With no benchmark scores available, the analysis relies on specification-derived capabilities.

The B300 dominates in FP16 compute. Its 1,231.8 TFLOPS FP16 (16:1) is 24.3 times the RTX PRO 4500’s 50.70 TFLOPS FP16 (1:1). This gap reflects the B300’s tensor core focus and the 16:1 ratio, which trades precision for throughput. For workloads that use reduced precision, the B300 offers a substantial advantage.

In FP32, the B300’s 76.99 TFLOPS is 1.52 times the RTX PRO 4500’s 50.70 TFLOPS. This is a moderate lead, suggesting both can handle general compute, but the B300 still pulls ahead. The RTX PRO 4500’s FP16 equals its FP32 at 50.70 TFLOPS, indicating a 1:1 ratio that preserves precision.

Memory bandwidth favors the B300 decisively. The B300’s 4.10 TB/s is 5.12 times the RTX PRO 4500’s 800.3 GB/s. For memory-bound workloads, this difference can be more impactful than raw compute. The B300’s 144 GB capacity is 4.5 times the RTX PRO 4500’s 32 GB, allowing larger datasets to reside on-chip.

The RTX PRO 4500 wins in pixel rate. Its 270.5 GPixel/s is 5.55 times the B300’s 48.77 GPixel/s. This comes from the RTX PRO 4500’s 112 ROPs versus the B300’s 24 ROPs. The RTX PRO 4500 also has a higher boost clock at 2415 MHz versus 2032 MHz, which contributes to its rasterization throughput.

Texture rate favors the B300. The B300’s 1,202.9 GTexel/s is 1.52 times the RTX PRO 4500’s 792.1 GTexel/s, matching the FP32 ratio. The B300’s higher TMU count (592 vs. 328) drives this advantage. The B300 also has more shading units: 18,944 versus 10,496, a 1.80 times difference.

Specification Differences

The two GPUs differ across nearly every specification field except process node, foundry, bus interface, production status, and generation. Both use 5 nm TSMC fabrication, PCIe 5.0 x16, have Active production status, and belong to the Server Blackwell (Bxx) generation. Both have no display outputs and no launch MSRP listed.

The B300 uses the GB110 chip with Blackwell Ultra architecture; the RTX PRO 4500 uses GB203 with Blackwell 2.0. The B300 has 104,000 million transistors; the RTX PRO 4500 has 45,600 million. The RTX PRO 4500 has a die size of 378 mm² and transistor density of 120.6M per mm²; the B300 has neither listed.

Clock speeds differ: B300 base 1665 MHz, boost 2032 MHz; RTX PRO 4500 base 1215 MHz, boost 2415 MHz. Memory clocks: B300 2000 MHz with 8 Gbps effective; RTX PRO 4500 1563 MHz with 25 Gbps effective. Memory size: B300 144 GB HBM3e; RTX PRO 4500 32 GB GDDR7. Bus width: B300 4096 bit; RTX PRO 4500 256 bit. Bandwidth: B300 4.10 TB/s; RTX PRO 4500 800.3 GB/s.

Shader resources: B300 has 18,944 shading units, 592 TMUs, 24 ROPs; RTX PRO 4500 has 10,496 shading units, 328 TMUs, 112 ROPs. Tensor cores: B300 592; RTX PRO 4500 328. RT cores: B300 none listed; RTX PRO 4500 82. Pixel rate: B300 48.77 GPixel/s; RTX PRO 4500 270.5 GPixel/s. Texture rate: B300 1,202.9 GTexel/s; RTX PRO 4500 792.1 GTexel/s.

Power and form factor: B300 TDP 1400 W, SXM module, no power connector listed, suggested PSU 1800 W; RTX PRO 4500 TDP 165 W, single-slot, 1x 16-pin connector, suggested PSU 450 W. The RTX PRO 4500 has dimensions of 267 mm length, 111 mm height, 40 mm width; the B300 has none. API support: RTX PRO 4500 lists DirectX 12 Ultimate (12_2), OpenGL 4.6, Vulkan 1.4; B300 lists none.

Release dates differ: B300 September 10, 2025; RTX PRO 4500 March 16, 2026. Both share the same predecessor (Server Hopper) and successor (Server Rubin). Neither has a launch MSRP in the database.

Where Each One Wins

The B300 wins in memory capacity, memory bandwidth, FP32 compute, FP16 compute, texture rate, shading units, TMUs, tensor cores, and transistor count. Its 144 GB HBM3e with 4.10 TB/s bandwidth suits large-scale AI inference and training where model weights and activations exceed 32 GB. The 1,231.8 TFLOPS FP16 throughput indicates a strong capability for mixed-precision neural network workloads. The 1.52 times FP32 lead over the RTX PRO 4500 also supports general scientific computing with higher precision.

The RTX PRO 4500 wins in pixel rate, ROP count, boost clock, and API support. Its 270.5 GPixel/s pixel rate is 5.55 times the B300’s, which points to stronger rasterization throughput for graphics rendering tasks. The 112 ROPs versus 24 is a clear structural advantage. The higher boost clock of 2415 MHz versus 2032 MHz supports latency-sensitive workloads. The explicit DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4 support makes it applicable to graphics pipelines, while the B300 has no listed API support. The RTX PRO 4500’s 32 GB GDDR7, while smaller, still provides 800.3 GB/s bandwidth and a 256-bit bus, sufficient for many rendering and compute tasks.

The power envelope separates them. The B300 requires 1400 W TDP and an 1800 W PSU, making it a data-center-scale component. The RTX PRO 4500 needs 165 W TDP and a 450 W PSU, which fits standard server chassis. The single-slot form factor and 267 mm length of the RTX PRO 4500 allow denser installations than the SXM module of the B300.

The RTX PRO 4500 also includes 82 ray tracing cores, a feature not listed for the B300. This suggests the RTX PRO 4500 can handle ray-traced workloads, while the B300’s design focuses on tensor-heavy compute. The RTX PRO 4500’s 1:1 FP16 to FP32 ratio means it does not sacrifice precision for throughput, unlike the B300’s 16:1 ratio.

The Verdict

The data shows two products with opposite design priorities. The NVIDIA B300 is a high-power, high-memory accelerator for compute-intensive server workloads. Its 144 GB HBM3e, 4.10 TB/s bandwidth, and 1,231.8 TFLOPS FP16 position it for large-scale AI and HPC tasks where memory capacity and reduced-precision throughput are critical. The 1400 W TDP and SXM form factor indicate a dedicated accelerator slot in a server, not a general-purpose card.

The NVIDIA RTX PRO 4500 Blackwell Server is a lower-power, single-slot card with broader graphics capability. Its 270.5 GPixel/s pixel rate, 112 ROPs, and 82 ray tracing cores support rendering workloads. The 32 GB GDDR7 with 800.3 GB/s bandwidth handles moderate datasets. The 165 W TDP and 450 W PSU requirement make it suitable for servers with limited power budgets. The explicit API support for DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4 confirms its graphics-oriented role.

For buyers choosing between them, the decision hinges on workload type. The B300 delivers 5.12 times the memory bandwidth and 24.3 times the FP16 compute of the RTX PRO 4500, making it the clear choice for large language models, deep learning training, and memory-bound scientific simulations. The RTX PRO 4500 offers 5.55 times the pixel rate and includes ray tracing cores, making it the better fit for rendering, visualization, and mixed graphics-compute tasks.

The release dates show the B300 launched first on September 10, 2025, with the RTX PRO 4500 following on March 16, 2026. Both remain in Active production. Neither has benchmark scores in the database, so performance claims rest on specification analysis. The percentile ranking of 50 for both is a neutral placeholder, not a measured result.

The B300’s 18,944 shading units and 592 tensor cores outnumber the RTX PRO 4500’s 10,496 and 328, respectively, reinforcing its compute lead. The RTX PRO 4500’s 378 mm² die and 120.6M per mm² density show a more compact implementation, while the B300’s 104,000 million transistors indicate a larger, more complex chip. The lack of die size for the B300 prevents a density comparison.

In a server environment with unlimited power and cooling, the B300 is the superior compute engine. Its FP32 lead of 1.52 times and FP16 lead of 24.3 times directly translate to faster execution for numerical workloads. The RTX PRO 4500, with its 165 W TDP, is the efficient choice for racks where power density matters. Its 112 ROPs and ray tracing cores deliver graphics features the B300 lacks entirely.

The database records no wins for either product in head-to-head benchmarks, and both have zero average benchmark scores. This absence of measured data means the verdict rests on architectural and specification differences. The B300 wins decisively on memory and compute throughput. The RTX PRO 4500 wins on rasterization, ray tracing, and power efficiency. Each product occupies a distinct niche, and the selection depends on whether the priority is massive parallel compute or balanced graphics and compute in a low-power package.