AMD Radeon RX 6600 LE vs NVIDIA GeForce RTX 4080 Comparison

The NVIDIA GeForce RTX 4080 wins this matchup decisively, taking both recorded head-to-head benchmarks against the AMD Radeon RX 6600 LE by margins of 67.8 percent and 72.5 percent. The recorded data leaves no ambiguity: the RTX 4080 is in a different performance class, while the RX 6600 LE counters with far lower power draw, a much smaller physical footprint, and compute throughput that still places it in the 91st percentile of all GPUs in the database. This comparison is less a contest than a study in what two different design philosophies deliver.

Where Each One Wins

The RTX 4080 wins everywhere performance is the metric. In Geekbench OpenCL it scored 214739 against 69229 for the RX 6600 LE, a 67.8 percent advantage. In Geekbench Vulkan the gap widens further: 263779 against 72428, a 72.5 percent advantage for the NVIDIA card. Those are the only two tests where both GPUs have recorded results, and the RX 6600 LE won neither.

The RX 6600 LE wins on efficiency and practicality. Its TDP is 132 W against 320 W for the RTX 4080, it draws power through a single 8-pin connector rather than a 16-pin connector, and its suggested PSU is 300 W versus 700 W. Physically, it is a dual-slot card measuring 190 mm long, 110 mm tall, and 40 mm wide, while the RTX 4080 is a triple-slot card at 310 mm long, 140 mm tall, and 61 mm wide. Anyone with a compact case or a modest power supply can fit the RX 6600 LE where the RTX 4080 simply cannot go.

There is also a nuance in the database percentile rankings worth understanding. The RX 6600 LE sits in the 91st percentile versus all GPUs, higher than the RTX 4080's 86th percentile. This does not mean the Radeon is faster. It means each card is ranked within the pool of recorded results for its own test set, and the RTX 4080's average score of 54247 spans a wider range of tests including PassMark and 3DMark entries. The head-to-head numbers are the direct comparison, and they favor NVIDIA without exception.

Architecture Differences

These GPUs come from consecutive design eras and it shows in every layer of the specification. The RX 6600 LE is built on TSMC's 7 nm process using the Navi 23 chip and AMD's RDNA 2.0 architecture, packing 11,060 million transistors onto a 237 mm² die for a density of 46.7M per mm². The RTX 4080 uses TSMC's 5 nm process with the AD103 chip and NVIDIA's Ada Lovelace architecture, fitting 45,900 million transistors into 379 mm² at a density of 121.1M per mm². The density figure more than doubles from one generation node to the next, and the transistor count is roughly four times higher.

The core counts scale accordingly. The RX 6600 LE has 1792 shading units, 112 TMUs, 64 ROPs, and 28 ray tracing cores, with no tensor cores listed. The RTX 4080 has 9728 shading units, 304 TMUs, 112 ROPs, 76 ray tracing cores, and 304 tensor cores. The presence of dedicated tensor hardware on the Ada card is a structural difference with direct consequences for AI and machine learning workloads, where the RX 6600 LE has no equivalent listed.

Memory is another clear dividing line. The RX 6600 LE carries 8 GB of GDDR6 on a 128-bit bus at 1750 MHz, delivering 14 Gbps effective speed and 224.0 GB/s of bandwidth. The RTX 4080 pairs 16 GB of GDDR6X with a 256-bit bus at 1400 MHz, reaching 22.4 Gbps effective and 716.8 GB/s of bandwidth. That is more than three times the memory bandwidth and double the capacity, which matters for high-resolution textures, large datasets, and compute workloads that exceed an 8 GB frame buffer.

Clock behavior differs too. The RX 6600 LE runs a 1626 MHz base, a 2045 MHz game clock, and a 2495 MHz boost. The RTX 4080 lists a 2205 MHz base and a 2505 MHz boost with no game clock recorded. Peak boost clocks are nearly identical, so the performance gap comes almost entirely from core count, memory subsystem, and architecture, not frequency. The bus interfaces also differ: the Radeon connects over PCIe 4.0 x8 while the GeForce uses the full PCIe 4.0 x16 link.

Both cards support DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4, and both offer one HDMI 2.1 output alongside three DisplayPort 1.4a connectors. Software API support is therefore equivalent on paper.

Head-to-Head Benchmarks

Only two tests appear in the database for both cards, and both are landslide results.

Geekbench OpenCL: the RTX 4080 scored 214739, the RX 6600 LE scored 69229. NVIDIA wins by 67.8 percent. OpenCL measures general GPU compute, and the result tracks the raw throughput gap closely: 48.74 TFLOPS FP32 for the RTX 4080 versus 8.942 TFLOPS for the RX 6600 LE, a difference of roughly five and a half times on paper that manifests as just under three times in this measured workload.

Geekbench Vulkan: the RTX 4080 scored 263779, the RX 6600 LE scored 72428. NVIDIA wins by 72.5 percent, the largest gap in the recorded data. The Vulkan result is instructive because the RX 6600 LE actually scores better in Vulkan than in OpenCL, yet still trails by a wide margin. The RTX 4080's Vulkan score is also its strongest single number in the database, aided by its 761.5 GTexel/s texture rate against 279.4 GTexel/s for the Radeon.

The RTX 4080's broader record reinforces the picture. It posted 34457 in PassMark G3D, 20671 in PassMark GPU Compute, 6567 in 3DMark Steel Nomad DX12, and scores of 370, 314, 204, and 132 in PassMark DirectX 9, 11, 10, and 12 respectively, plus 1239 in PassMark G2D. None of these tests have a matching RX 6600 LE result, but they establish the Ada card's ceiling.

Context from each card's rival circle tells the same story. The RX 6600 LE's average score of 70829 puts it within about one percent of the NVIDIA RTX A3000 Mobile (70140), about one percent ahead of the Quadro P6000 (69986), slightly behind the RX 6650M (71768), and marginally ahead of the Radeon Pro WX 8200 (69870). It competes in a mixed field of older professional and mobile parts. The RTX 4080's average of 54247 sits essentially even with the RTX 4080 SUPER (54209), just ahead of the Radeon Pro W5700X (54828 is above it), and ahead of the RX 6750 GRE 12 GB (55698, also above it) and the Radeon 8060S (55757). Its closest rival is its own SUPER variant, which is the signature of a card at the top of its performance bracket.

FAQ

Q: Is the RTX 4080 faster than the RX 6600 LE?

A: Yes, in every recorded head-to-head test. It wins Geekbench OpenCL by 67.8 percent (214739 versus 69229) and Geekbench Vulkan by 72.5 percent (263779 versus 72428).

Q: Which card uses less power?

A: The RX 6600 LE, by a wide margin. Its TDP is 132 W with a single 8-pin connector and a 300 W suggested PSU, versus 320 W, a 16-pin connector, and a 700 W suggested PSU for the RTX 4080.

Q: How much more memory does the RTX 4080 have?

A: It has 16 GB of GDDR6X on a 256-bit bus with 716.8 GB/s of bandwidth. The RX 6600 LE has 8 GB of GDDR6 on a 128-bit bus with 224.0 GB/s.

Q: Are both cards still in production?

A: No. The RX 6600 LE is listed as Active, while the RTX 4080 is listed as End-of-life. The RTX 4080 launched on September 19, 2022 at a launch MSRP of 1,199 USD, and the RX 6600 LE followed on December 7, 2023.

Q: Which card fits a smaller case?

A: The RX 6600 LE. It is a dual-slot card measuring 190 mm long, while the RTX 4080 is a triple-slot card measuring 310 mm long, 140 mm tall, and 61 mm wide.

Q: Do both cards support ray tracing?

A: Yes. The RX 6600 LE has 28 ray tracing cores and the RTX 4080 has 76, and both support DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4.

The Verdict

Buy the RTX 4080 if raw performance is the priority and the supporting infrastructure exists. It delivers roughly three times the compute performance of the RX 6600 LE in both shared benchmarks, has double the memory at triple the bandwidth, includes 304 tensor cores the Radeon lacks entirely, and posts higher pixel rate (280.6 versus 159.7 GPixel/s) and texture rate (761.5 versus 279.4 GTexel/s). The costs are concrete: a 320 W TDP, a 700 W suggested PSU, a triple-slot footprint over 310 mm long, and an end-of-life production status.

Pick the RX 6600 LE for efficiency-constrained or space-constrained builds. It delivers respectable throughput (8.942 TFLOPS FP32, 17.88 TFLOPS FP16 at a 2:1 rate), holds its own against its nearest rivals within roughly a percent on either side, and does all of it on 132 W through a single 8-pin connector in a compact dual-slot frame. It remains in active production. It is not a performance rival to the RTX 4080, and the data never suggests otherwise, but within its own class it is competitive, and its percentile ranking of 91 reflects a strong showing across its recorded test set.

Specification Differences

| Field | AMD Radeon RX 6600 LE | NVIDIA GeForce RTX 4080 |

|---|---|---|

| Chip | Navi 23 | AD103 |

| Architecture | RDNA 2.0 | Ada Lovelace |

| Process node | 7 nm | 5 nm |

| Transistors | 11,060 million | 45,900 million |

| Die size | 237 mm² | 379 mm² |

| Transistor density | 46.7M / mm² | 121.1M / mm² |

| Base clock | 1626 MHz | 2205 MHz |

| Game clock | 2045 MHz | Not listed |

| Boost clock | 2495 MHz | 2505 MHz |

| Memory size | 8 GB GDDR6 | 16 GB GDDR6X |

| Bus width | 128 bit | 256 bit |

| Memory bandwidth | 224.0 GB/s | 716.8 GB/s |

| Effective memory speed | 14 Gbps | 22.4 Gbps |

| Shading units | 1792 | 9728 |

| TMUs | 112 | 304 |

| ROPs | 64 | 112 |

| Ray tracing cores | 28 | 76 |

| Tensor cores | None listed | 304 |

| Pixel rate | 159.7 GPixel/s | 280.6 GPixel/s |

| Texture rate | 279.4 GTexel/s | 761.5 GTexel/s |

| FP32 | 8.942 TFLOPS | 48.74 TFLOPS |

| FP16 | 17.88 TFLOPS (2:1) | 48.74 TFLOPS (1:1) |

| TDP | 132 W | 320 W |

| Slot width | Dual-slot | Triple-slot |

| Power connectors | 1x 8-pin | 1x 16-pin |

| Suggested PSU | 300 W | 700 W |

| Bus interface | PCIe 4.0 x8 | PCIe 4.0 x16 |

| Length | 190 mm | 310 mm |

| Height | 110 mm | 140 mm |

| Width | 40 mm | 61 mm |

| Release date | December 7, 2023 | September 19, 2022 |

| Production status | Active | End-of-life |

| Launch MSRP | Not listed | 1,199 USD |

| Average benchmark score | 70829 | 54247 |

| Percentile vs all GPUs | 91 | 86 |