AMD Radeon R7 M365X vs NVIDIA Quadro P400 Comparison

The Verdict

The benchmark data splits the two cards almost evenly, but the winner depends entirely on the workload. The AMD Radeon R7 M365X takes the OpenCL crown with a decisive 39.8% lead, scoring 5939 against the Quadro P400's 4249. The NVIDIA Quadro P400 answers back in Vulkan, posting 5119 versus 4893, a 4.4% margin. If your applications lean on OpenCL compute, the AMD card is the clear choice. If Vulkan performance matters more, the NVIDIA card has the edge. The AMD Radeon R7 M365X also holds a higher overall percentile rank at 32, while the Quadro P400 sits at 27. The average benchmark score reflects this too: 5416 for AMD versus 4684 for NVIDIA. However, the Quadro P400 brings a more modern architecture, a newer feature set, and professional display outputs. The data suggests the AMD card wins raw compute in one API, but the NVIDIA card offers broader modern API support and a more refined professional package.

Architecture Differences

The two cards come from different architectural generations and foundries. The AMD Radeon R7 M365X uses the Litho chip built on GCN 1.0 architecture, manufactured on a 28 nm process at TSMC. It packs 950 million transistors into a 77 mm² die, yielding a transistor density of 12.3 million per square millimeter. The NVIDIA Quadro P400 uses the GP107 chip with Pascal architecture, built on a 14 nm process at Samsung. It contains 3,300 million transistors on a 132 mm² die, achieving a transistor density of 25.0 million per square millimeter. The Pascal chip is newer and significantly denser.

The AMD card belongs to the Gem System generation, specifically the R7 M300 family, while the NVIDIA card is part of the Quadro Pascal generation, the Px000 series. AMD's GCN 1.0 architecture supports DirectX 12 (11_1), while NVIDIA's Pascal supports DirectX 12 (12_1), a higher feature level. Both support OpenGL 4.6, but NVIDIA's Vulkan support is version 1.4 compared to AMD's 1.2.170, indicating a more up-to-date Vulkan implementation on the NVIDIA side. The AMD card has 384 shading units, 24 texture mapping units, and 8 raster output units. The NVIDIA card has 256 shading units, 16 TMUs, and 16 ROPs. Fewer shading units but double the ROPs gives the Pascal card a different workload profile.

Head-to-Head Benchmarks

The most striking result in the database is the OpenCL benchmark, where the AMD Radeon R7 M365X scores 5939 against the Quadro P400's 4249. That is a 39.8% advantage, a substantial gap that shows the GCN architecture's strength in OpenCL compute workloads. The AMD card's average benchmark score of 5416 also sits well above the NVIDIA card's 4684, a difference of 732 points or roughly 15.6%. In the nearest rival comparison, the AMD card sits close to the AMD Radeon 610M (5444, 0.5% lower), the NVIDIA Quadro M4000 (5467, 0.9% lower), the Intel UHD Graphics P630 (5370, 0.9% higher), and the AMD Radeon R7 M445 (5358, 1.1% higher). These are tight margins, all within about a point of the AMD card's average.

The Vulkan benchmark flips the result. The NVIDIA Quadro P400 scores 5119 against the AMD card's 4893, a 4.4% lead for NVIDIA. This margin is much smaller than AMD's OpenCL advantage, but it is consistent with Pascal's newer Vulkan support (version 1.4 versus 1.2.170). The Quadro P400's nearest rivals include the AMD Radeon RX 9060 XT 16 GB (4657, 0.6% lower), the AMD Radeon R5 M320 (4657, 0.6% lower), the AMD Radeon R8 M445DX (4727, 0.9% higher), and the NVIDIA GeForce GTX 970M (4628, 1.2% higher). The NVIDIA card's average score of 4684 places it in a cluster where the differences are small, but the AMD card's average is clearly higher.

The head-to-head record is one win each. The AMD card wins OpenCL by a wide margin, and the NVIDIA card wins Vulkan by a modest one. The practical takeaway: if a user's software stack is OpenCL-heavy, the AMD card delivers dramatically better results. If Vulkan is the primary API, the NVIDIA card is the safer pick, though the margin is not overwhelming.

Specification Differences

The two cards differ across nearly every major specification. The AMD Radeon R7 M365X has 1024 MB of GDDR5 memory on a 128-bit bus, delivering 64.00 GB/s of bandwidth. The NVIDIA Quadro P400 has 2 GB of GDDR5 on a 64-bit bus, delivering 32.06 GB/s. The AMD card has twice the bus width and twice the bandwidth, while the NVIDIA card has twice the memory capacity. The AMD card's memory runs at 1000 MHz (4 Gbps effective), while the NVIDIA card's memory runs at 1002 MHz (4 Gbps effective), a negligible difference in clock but a large difference in bus width.

The NVIDIA card has explicit clock speeds: a base of 1228 MHz and a boost of 1252 MHz. The AMD card's base and boost clocks are not recorded in the database. The AMD card's pixel rate is 6.600 GPixel/s, and its texture rate is 19.80 GTexel/s. The NVIDIA card's pixel rate is 20.03 GPixel/s, and its texture rate is 20.03 GTexel/s. Despite having fewer TMUs, the NVIDIA card achieves a higher texture rate due to its higher clock speed. The pixel rate difference is stark: 20.03 GPixel/s versus 6.600 GPixel/s, a 203% advantage for NVIDIA. The FP32 performance is close: 633.6 GFLOPS for AMD versus 641.0 GFLOPS for NVIDIA, a 1.2% difference. The NVIDIA card also records an FP16 figure of 10.02 GFLOPS (1:64), while the AMD card has no FP16 entry.

The power and physical specifications also differ. The NVIDIA Quadro P400 has a TDP of 30 W, is single-slot, requires no power connectors, and suggests a 200 W PSU. The AMD card has no TDP, slot width, power connector, or PSU data recorded. The NVIDIA card measures 150 mm in length and 69 mm in height. The AMD card has no dimensions recorded. The bus interface differs: the AMD card uses PCIe 3.0 x8, while the NVIDIA card uses PCIe 3.0 x16. The display outputs also differ: the NVIDIA card offers 3x mini-DisplayPort 1.4a, while the AMD card has no display output data listed.

FAQ

Q: Which card performs better in OpenCL benchmarks?

A: The AMD Radeon R7 M365X scores 5939 in Geekbench OpenCL, which is 39.8% higher than the NVIDIA Quadro P400's 4249. This is the largest performance gap between the two cards.

Q: Which card performs better in Vulkan benchmarks?

A: The NVIDIA Quadro P400 scores 5119 in Geekbench Vulkan, which is 4.4% higher than the AMD Radeon R7 M365X's 4893. The NVIDIA card also supports Vulkan 1.4, while the AMD card supports Vulkan 1.2.170.

Q: How do the average benchmark scores compare?

A: The AMD Radeon R7 M365X has an average benchmark score of 5416, while the NVIDIA Quadro P400 has an average of 4684. The AMD card's average is higher by 732 points, and it also ranks higher in overall percentile (32 vs. 27).

Q: What is the memory configuration difference?

A: The AMD Radeon R7 M365X has 1024 MB of GDDR5 on a 128-bit bus with 64.00 GB/s bandwidth. The NVIDIA Quadro P400 has 2 GB of GDDR5 on a 64-bit bus with 32.06 GB/s bandwidth. The AMD card has double the bus width and bandwidth, while the NVIDIA card has double the capacity.

Q: Which card has a higher pixel rate?

A: The NVIDIA Quadro P400 has a pixel rate of 20.03 GPixel/s, which is over three times the AMD Radeon R7 M365X's 6.600 GPixel/s. This suggests the NVIDIA card is better suited for fill-rate-heavy tasks.

Q: What are the power requirements for the NVIDIA Quadro P400?

A: The NVIDIA Quadro P400 has a TDP of 30 W, requires no power connectors, and suggests a 200 W PSU. The AMD Radeon R7 M365X has no power data recorded in the database.

Where Each One Wins

The AMD Radeon R7 M365X wins in OpenCL compute workloads. The 39.8% lead in Geekbench OpenCL is the single largest benchmark gap in this comparison, and the card's 384 shading units provide a solid foundation for parallel compute tasks. The AMD card also has a significant bandwidth advantage: 64.00 GB/s versus 32.06 GB/s, which helps in memory-intensive compute operations. Its average benchmark score of 5416 and percentile rank of 32 place it higher than the NVIDIA card in the overall database ranking. For users running OpenCL-based applications, the AMD card is the data-backed choice.

The NVIDIA Quadro P400 wins in Vulkan workloads and in several architectural aspects. Its Vulkan score of 5119 tops the AMD card's 4893, and it supports Vulkan 1.4, a newer specification than AMD's 1.2.170. The NVIDIA card also offers a higher DirectX feature level (12_1 versus 11_1), which matters for some modern applications. The pixel rate of 20.03 GPixel/s is more than triple the AMD card's 6.600 GPixel/s, making it better suited for rasterization-heavy tasks. The NVIDIA card's 2 GB of memory doubles the AMD card's capacity, which helps with larger textures or datasets. It also has a lower TDP at 30 W, requires no external power, and comes in a single-slot design with 3x mini-DisplayPort 1.4a outputs. For Vulkan-based applications, or for users who need a low-power professional card with modern display outputs, the NVIDIA card is the better fit.

The compute-heavy user should pick the AMD Radeon R7 M365X. The OpenCL score is decisively higher, and the bandwidth advantage is substantial. The Vulkan-oriented user, or the user prioritizing power efficiency and modern API support, should pick the NVIDIA Quadro P400. The data does not crown a single overall winner. It identifies two cards with different strengths, and the correct choice depends on the software environment and the specific performance metric that matters most.