AMD Radeon Pro WX 5100 vs AMD Radeon R7 350 Comparison

Head-to-Head Benchmarks

The recorded data shows a decisive performance gap between the AMD Radeon Pro WX 5100 and the AMD Radeon R7 350 across the two benchmark tests where both have recorded scores. In Geekbench OpenCL, the Pro WX 5100 scores 24,217 points against the R7 350's 7,792 points, a delta of 210.8% in favor of the professional card. That is not a marginal lead; it is a threefold advantage in raw compute throughput as measured by the OpenCL workload.

The Vulkan test tells an even more lopsided story. The Pro WX 5100 posts 26,909 points, while the R7 350 manages only 7,057 points. The delta here reaches 281.3%, meaning the Pro WX 5100 delivers nearly four times the Vulkan performance of the R7 350. For any application relying on modern graphics APIs, this gap is decisive.

It is worth contextualizing these scores against the broader database. The Pro WX 5100 sits at the 44th percentile of all GPUs, with an average benchmark score of 8,863. Its nearest rivals in the database include the AMD Radeon R9 M265X at 8,851 (0.1% behind), the AMD Radeon 550X at 8,918 (0.6% ahead), the NVIDIA GeForce RTX 3050 A Mobile at 8,746 (1.3% behind), and the NVIDIA GeForce GTX 460 v2 at 8,743 (1.4% behind). These are tight margins, all within 1.4% of each other, suggesting the Pro WX 5100 sits in a well-populated performance tier.

The R7 350, by contrast, holds the 40th percentile with an average score of 7,425. Its nearest rivals are the Intel UHD Graphics 750 at 7,441 (0.2% ahead), the AMD Radeon HD 8850M at 7,447 (0.3% ahead), the NVIDIA GeForce GTX 1650 at 7,472 (0.6% ahead), and the Intel Arc A310 at 7,550 (1.7% ahead). The R7 350 is at the bottom of its immediate cluster, though the differences are small.

The head-to-head data shows 2 wins for the Pro WX 5100 and 0 wins for the R7 350. Every single recorded comparison favors the newer, larger GPU. The OpenCL delta of 210.8% and the Vulkan delta of 281.3% are not close calls; they are category-level differences.

The Verdict

The data points to one clear conclusion: the AMD Radeon Pro WX 5100 is the superior product in every measured dimension. For users who need compute performance in OpenCL or Vulkan workloads, the choice is unambiguous. The Pro WX 5100 delivers 210.8% higher OpenCL scores and 281.3% higher Vulkan scores compared to the R7 350.

That said, the R7 350 is not without a place. Its average benchmark score of 7,425 places it just below the 40th percentile, and its nearest rivals are all within 1.7%, so it sits in a coherent performance band. For lightweight tasks, legacy applications, or systems where the R7 350 is already installed, the recorded numbers show it can hold its own against integrated graphics like the Intel UHD Graphics 750, which scores 7,441, a margin of only 0.2%. But for any workload where the Pro WX 5100's 8 GB of GDDR5 memory and 1792 shading units come into play, the R7 350's 2 GB and 512 shading units will be a bottleneck.

The percentile ranking reinforces this: the Pro WX 5100 at the 44th percentile is only 4 points ahead of the R7 350's 40th percentile in percentile terms, yet the raw benchmark deltas show a massive gulf. The percentile metric can be misleading here because it reflects the entire database distribution, not just these two cards. The head-to-head deltas of 210.8% and 281.3% are the more meaningful figures for direct comparison.

Users who prioritize compute performance, modern API support, or higher memory capacity should select the Pro WX 5100 without hesitation. Users who need a low-power, single-slot card for basic display output or very light compute might find the R7 350 adequate, but the data does not support choosing it over the Pro WX 5100 when performance is the criterion.

Architecture Differences

The two GPUs come from different generations of AMD's Graphics Core Next (GCN) architecture. The Pro WX 5100 uses GCN 4.0 on the Ellesmere chip, while the R7 350 uses GCN 1.0 on the Cape Verde chip. This is a three-generation jump in microarchitecture, which explains much of the performance disparity.

The manufacturing process differs as well. The Pro WX 5100 is built on a 14 nm process at GlobalFoundries, while the R7 350 uses a 28 nm process at TSMC. The smaller node allows the Pro WX 5100 to pack 5,700 million transistors onto a 232 mm² die, for a transistor density of 24.6 million per square millimeter. The R7 350 has 1,500 million transistors on a 123 mm² die, yielding a density of 12.2 million per square millimeter. The Pro WX 5100 more than doubles the transistor density, which directly contributes to its higher compute throughput.

The Pro WX 5100 belongs to the Radeon Pro Polaris generation (WX x100 series), while the R7 350 is from the Pirate Islands generation (R7 300 series). The release dates reflect this gap: the Pro WX 5100 launched on November 17, 2016, and the R7 350 on July 5, 2016. Both are end-of-life products now