AMD Radeon Pro WX 2100 vs NVIDIA GeForce GTX 465 Comparison

The AMD Radeon Pro WX 2100 and NVIDIA GeForce GTX 465 occupy the same 46th percentile among all GPUs, yet they achieve this standing through radically different means. The WX 2100 is a modern, low-power workstation card built on a 14 nm process, while the GTX 465 is a legacy, high-TDP desktop part from the Fermi era. The benchmark data shows a single head-to-head result, with the GTX 465 taking the win in Geekbench OpenCL by a margin of 8.2%, but the full picture involves power, features, and architectural trade-offs that matter more than a single synthetic score.

Head-to-Head Benchmarks

The only direct comparison available is the Geekbench OpenCL test, and the results are clear. The NVIDIA GeForce GTX 465 scores 9294, while the AMD Radeon Pro WX 2100 scores 8536. That gives the GTX 465 an 8.2% advantage. In raw compute terms, the GTX 465 delivers 855.4 GFLOPS of FP32 performance, whereas the WX 2100 pushes 1,248.3 GFLOPS. Despite the AMD card having 46% more FP32 throughput, the GTX 465 still wins the OpenCL benchmark, which suggests that the older Fermi architecture handles this particular workload more efficiently or that driver optimizations favor it.

Looking at the broader context, both cards sit within a tight cluster of rivals. The WX 2100's average benchmark score is 9653, which places it just 0.1% above the NVIDIA GeForce GTX 960M (9645) and 0.2% above the Quadro K5000 (9637). It trails the Quadro P4000 by 0.1% (9665) and the Tesla C2070 by 0.6% (9716). The GTX 465's average score is 9294, which is 0.1% below the GTX 850M (9302) and 0.2% below the Radeon R7 M380 (9313). It sits 0.2% above the GTX 960 (9273) and 0.8% above the Radeon Vega 8 (9221).

The WX 2100 also has a Geekbench Vulkan score of 10770, which the GTX 465 lacks entirely — the Fermi card has no Vulkan support listed. That is a significant gap for any modern workload or API-forward application. The Vulkan result also lifts the WX 2100's average benchmark score to 9653, compared to the GTX 465's 9294, meaning that outside the single OpenCL test, the AMD card has a higher average across all recorded benchmarks.

Neither card is a performance leader. The WX 2100 falls behind its nearest rival, the Quadro P4000, by a hair, and the GTX 465 is similarly mid-pack. The data suggests these are both entry-level performers, with the GTX 465 edging out a win in the one test they share, but the WX 2100 offering broader API support and a higher average score.

FAQ

Q: Which card wins the Geekbench OpenCL benchmark?

A: The NVIDIA GeForce GTX 465 wins with a score of 9294, beating the AMD Radeon Pro WX 2100's 8536 by 8.2%.

Q: Does the AMD Radeon Pro WX 2100 support Vulkan?

A: Yes, the WX 2100 lists Vulkan 1.3 support and scores 10770 in the Geekbench Vulkan test. The NVIDIA GeForce GTX 465 has no Vulkan support listed in its specifications.

Q: How do the two cards compare in terms of average benchmark scores?

A: The AMD Radeon Pro WX 2100 has an average benchmark score of 9653, while the NVIDIA GeForce GTX 465 averages 9294. The WX 2100 is the higher-scoring card overall.

Q: What is the memory configuration difference?

A: The WX 2100 has 2 GB of GDDR5 on a 64-bit bus with 48.00 GB/s bandwidth. The GTX 465 has 1024 MB of GDDR5 on a 256-bit bus with 102.7 GB/s bandwidth.

Q: Which card has a higher FP32 compute throughput?

A: The AMD Radeon Pro WX 2100 delivers 1,248.3 GFLOPS of FP32 performance, compared to 855.4 GFLOPS for the GTX 465. The WX 2100 is 46% faster on paper.

Q: What are the power requirements for each card?

A: The WX 2100 has a TDP of 35 W and requires no power connectors, with a suggested PSU of 200 W. The GTX 465 has a TDP of 200 W, needs two 6-pin connectors, and suggests a 550 W PSU.

Where Each One Wins

The NVIDIA GeForce GTX 465 wins the only direct benchmark comparison, taking the Geekbench OpenCL test by 8.2%. It also has a massive memory bandwidth advantage — 102.7 GB/s versus 48.00 GB/s — thanks to its 256-bit bus, which can benefit memory-heavy workloads. The GTX 465 has more texture mapping units (44 vs 32) and more ROPs (32 vs 16), which can help in certain rasterization and fill-rate-bound tasks. Its pixel rate is 13.38 GPixel/s and texture rate is 26.75 GTexel/s, both lower than the WX 2100's figures of 19.50 GPixel/s and 39.01 GTexel/s, but the raw OpenCL score favors NVIDIA.

The AMD Radeon Pro WX 2100 wins on overall average benchmark score (9653 vs 9294) and has a Vulkan score that the GTX 465 simply cannot match. It also has a much higher FP32 throughput (1,248.3 GFLOPS vs 855.4 GFLOPS) and supports FP16 at a 1:1 ratio, which the GTX 465 does not list. The WX 2100 has a higher pixel rate (19.50 GPixel/s vs 13.38 GPixel/s) and texture rate (39.01 GTexel/s vs 26.75 GTexel/s). It supports DirectX 12_0 and Vulkan 1.3, while the GTX 465 only reaches DirectX 11_0 and has no Vulkan. The AMD card is also dramatically more power-efficient, with a 35 W TDP versus 200 W.

Specification Differences

The two cards differ in nearly every measurable specification. The AMD Radeon Pro WX 2100 uses a 14 nm process and packs 2,200 million transistors on a 103 mm² die, while the NVIDIA GeForce GTX 465 uses a 40 nm process with 3,100 million transistors on a 529 mm² die. Transistor density tells the story: 21.4M per mm² for the WX 2100 versus 5.9M per mm² for the GTX 465.

Memory is a stark contrast. The WX 2100 has 2 GB of GDDR5 on a 64-bit bus, delivering 48.00 GB/s. The GTX 465 has 1024 MB on a 256-bit bus, delivering 102.7 GB/s. The GTX 465 has the bandwidth advantage, but the WX 2100 has twice the capacity.

Compute units differ as well. The WX 2100 has 512 shading units, 32 TMUs, and 16 ROPs. The GTX 465 has 352 shading units, 44 TMUs, and 32 ROPs. The clock speeds are not directly comparable since the GTX 465 lists no base or boost clock, only a memory clock of 802 MHz (3.2 Gbps effective). The WX 2100 runs at 925 MHz base and 1219 MHz boost, with memory at 1500 MHz (6 Gbps effective).

Power and physical design are worlds apart. The WX 2100 is a single-slot card, 168 mm long, with no power connectors and a 35 W TDP. The GTX 465 is a dual-slot card, 241 mm long, requiring two 6-pin connectors and a 200 W TDP. The suggested PSU is 200 W for the AMD and 550 W for the NVIDIA. The WX 2100 uses PCIe 3.0 x8, while the GTX 465 uses PCIe 2.0 x16.

Display outputs differ too. The WX 2100 offers 1x DisplayPort 1.4a and 2x mini-DisplayPort 1.4a. The GTX 465 has 2x DVI and 1x mini-HDMI 1.3a. The API support is also different: the WX 2100 supports DirectX 12 (12_0), OpenGL 4.6, and Vulkan 1.3. The GTX 465 supports DirectX 12 (11_0) and OpenGL 4.6, but no Vulkan.

Architecture Differences

The architectural gap is generational. The AMD Radeon Pro WX 2100 is built on GCN 4.0 architecture, using the Lexa chip, and belongs to the Radeon Pro Polaris (WX x100) generation. It is manufactured by GlobalFoundries on a 14 nm process. The NVIDIA GeForce GTX 465 is built on the Fermi architecture, using the GF100 chip, and belongs to the GeForce 400 generation. It is manufactured by TSMC on a 40 nm process.

These are different design philosophies from different eras. The WX 2100 is a modern, efficiency-focused design with a tiny 103 mm² die and a 35 W TDP. The GTX 465 is a large, power-hungry chip from 2010, with a 529 mm² die and a 200 W TDP. The transistor count is higher on the GTX 465 (3,100 million vs 2,200 million), but the WX 2100 achieves far greater density.

Feature support reflects the age difference. The WX 2100 supports FP16 at a 1:1 ratio with FP32, while the GTX 465 lists no FP16 support. The WX 2100 has Vulkan 1.3 support; the GTX 465 has none. The WX 2100 reaches DirectX 12_0, while the GTX 465 only reaches DirectX 11_0. Neither card has ray tracing or tensor cores. The WX 2100's display outputs are modern DisplayPort 1.4a, while the GTX 465 relies on DVI and mini-HDMI 1.3a.

The production status for both is end-of-life, but the release dates are seven years apart. The WX 2100 was released in 2017, with a launch MSRP of 149 USD. The GTX 465 was released in 2010, with a launch MSRP of 279 USD.

The Verdict

The data points to a clear split based on workload and priorities. If you are running OpenCL-heavy tasks and care about raw memory bandwidth, the NVIDIA GeForce GTX 465 is the winner — it beats the WX 2100 by 8.2% in the only shared benchmark. Its 256-bit bus and 102.7 GB/s bandwidth are substantial advantages for certain compute tasks, and it has double the ROPs and more TMUs.

But the GTX 465 is a relic. It requires 200 W of power, a 550 W PSU, and two 6-pin connectors. It has no Vulkan support, only 1024 MB of memory, and a 40 nm process that makes it physically enormous compared to the WX 2100. Its DirectX 11_0 support limits modern gaming and compute APIs.

The AMD Radeon Pro WX 2100 is the more balanced and future-proof option. It has a higher average benchmark score (9653 vs 9294), supports Vulkan 1.3 with a score of 10770, and offers 2 GB of memory. It has 46% more FP32 throughput (1,248.3 GFLOPS vs 855.4 GFLOPS) and supports FP16. It is dramatically more power-efficient — 35 W TDP, no power connectors, single-slot design — and uses modern DisplayPort 1.4a outputs. It supports PCIe 3.0 x8 versus the GTX 465's PCIe 2.0 x16.

For a workstation or a system where power, space, and modern API support matter, the WX 2100 is the obvious choice. For a legacy compute workload that specifically rewards the GTX 465's memory bandwidth and OpenCL performance, the older card has a narrow edge. The benchmark data shows one win for NVIDIA, but the overall average and feature set favor AMD. Choose based on the specific workload; the GTX 465 wins the test it shares, but the WX 2100 wins the broader battle.