AMD Radeon Pro W6600M vs NVIDIA GeForce RTX 5080 Comparison

The AMD Radeon Pro W6600M and NVIDIA GeForce RTX 5080 occupy entirely different corners of the GPU market, and the benchmark data reflects that chasm. The W6600M is an end-of-life mobile workstation part built on RDNA 2.0, while the RTX 5080 is an active desktop flagship built on Blackwell 2.0. In the two shared head-to-head benchmarks, the RTX 5080 wins decisively, but the W6600M holds its own in its specific niche. Here is a breakdown of what the data shows.

Where Each One Wins

The NVIDIA GeForce RTX 5080 is the undisputed winner in raw compute and graphics performance. In the Geekbench OpenCL test, it scores 235,901 against the W6600M’s 56,140, a delta of -76.2% in favor of NVIDIA. In Geekbench Vulkan, the gap is similar: 255,450 versus 67,652, a -73.5% delta. The RTX 5080 wins both head-to-head tests, giving it a 2-0 record. Its average benchmark score across all tests is 56,083, though this is dragged down by its low Passmark DirectX scores (ranging from 151 to 389), which are likely not representative of its true gaming or compute potential. The RTX 5080’s strongest result is its Passmark G3D score of 36,565, and it also posts a strong Passmark GPU Compute score of 21,789.

The AMD Radeon Pro W6600M wins in the context of its intended use case: mobile workstations. It is an IGP (integrated graphics processor) with a 90 W TDP, meaning it requires no power connectors and is designed for laptops. It has no direct head-to-head wins, but its average benchmark score of 61,896 is actually higher than the RTX 5080’s average of 56,083. This is because the W6600M only has two Geekbench scores (56,140 and 67,652), both of which are solid, while the RTX 5080’s Passmark DirectX scores are anomalously low. In terms of percentile ranking, the W6600M sits at the 89th percentile of all GPUs, while the RTX 5080 is at the 87th percentile — a counterintuitive result driven by the test suite composition. For mobile professional work where power efficiency is paramount, the W6600M is the sensible choice; for any desktop workload demanding maximum throughput, the RTX 5080 is the clear pick.

FAQ

Q: Which GPU has the higher average benchmark score?

A: The AMD Radeon Pro W6600M has a higher average benchmark score of 61,896 compared to the NVIDIA GeForce RTX 5080’s 56,083. This is because the W6600M’s two Geekbench scores are both above 56,000, while the RTX 5080’s Passmark DirectX scores (151 to 389) pull its average down significantly.

Q: How much faster is the RTX 5080 in Geekbench OpenCL?

A: The RTX 5080 scores 235,901 in Geekbench OpenCL, which is 76.2% higher than the W6600M’s 56,140. In absolute terms, the RTX 5080 is roughly four times faster in this test.

Q: Does the W6600M beat the RTX 5080 in any benchmark?

A: No. In the two head-to-head benchmarks available (Geekbench OpenCL and Geekbench Vulkan), the RTX 5080 wins both. The W6600M’s higher average score is purely a function of the limited test set and the RTX 5080’s low Passmark DirectX results.

Q: What is the memory configuration difference?

A: The W6600M has 8 GB of GDDR6 memory on a 128-bit bus, yielding 224.0 GB/s bandwidth. The RTX 5080 has 16 GB of GDDR7 memory on a 256-bit bus, yielding 960.0 GB/s bandwidth — over four times the bandwidth of the AMD part.

Q: Which GPU has a higher transistor density?

A: The RTX 5080 has a transistor density of 120.6M per mm², compared to the W6600M’s 46.7M per mm². This is despite the RTX 5080 using a larger 5 nm process node compared to the W6600M’s 7 nm node, and it has over four times the total transistor count (45,600 million versus 11,060 million).

Q: What are the power requirements for each?

A: The W6600M has a 90 W TDP and requires no power connectors, making it suitable for integrated mobile use. The RTX 5080 has a 360 W TDP, requires a single 16-pin power connector, and suggests a 750 W power supply unit.

Head-to-Head Benchmarks

The data is unambiguous: the RTX 5080 crushes the W6600M in both available tests. In Geekbench OpenCL, the RTX 5080 scores 235,901 versus the W6600M’s 56,140. That is a 76.2% advantage for NVIDIA, meaning the RTX 5080 delivers more than four times the OpenCL throughput. This test typically reflects raw compute capability across a wide range of workloads, from physics simulations to machine learning inference.

In Geekbench Vulkan, the margin narrows slightly but remains dominant. The RTX 5080 scores 255,450 against the W6600M’s 67,652, a 73.5% lead. Vulkan is a low-level graphics API that stresses both the GPU’s shader throughput and its driver efficiency. The RTX 5080’s 10,752 shading units and 56.28 TFLOPS of FP32 performance give it a massive raw advantage over the W6600M’s 1,792 shading units and 7.290 TFLOPS. Even with the W6600M’s 2:1 FP16 ratio (14.58 TFLOPS), it cannot compete with the RTX 5080’s 1:1 FP16 rate of 56.28 TFLOPS.

The RTX 5080’s pixel rate of 293.1 GPixel/s and texture rate of 879.3 GTexel/s are similarly far ahead of the W6600M’s 130.2 GPixel/s and 227.8 GTexel/s. For any real-time rendering workload, the RTX 5080 is in a different league. The W6600M’s only consolation is that its two Geekbench scores are internally consistent, suggesting stable performance for a mobile part, whereas the RTX 5080’s Passmark scores are erratic (e.g., 208 in DirectX 10, 324 in DirectX 11, 151 in DirectX 12, 389 in DirectX 9), which may indicate driver or test-specific quirks that do not reflect its true capability.

Specification Differences

The specification gap between these two GPUs is vast. The W6600M uses the Navi 23 chip with 11,060 million transistors on a 237 mm² die, manufactured on TSMC’s 7 nm process. The RTX 5080 uses the GB203 chip with 45,600 million transistors on a 378 mm² die, manufactured on TSMC’s 5 nm process. The RTX 5080’s transistor density is 120.6M / mm² versus the W6600M’s 46.7M / mm².

Clock speeds differ substantially: the W6600M runs at a base of 1224 MHz and boost of 2034 MHz, while the RTX 5080 runs at 2295 MHz base and 2617 MHz boost. Memory is a major differentiator: the W6600M has 8 GB GDDR6 at 1750 MHz (14 Gbps effective) on a 128-bit bus for 224.0 GB/s, while the RTX 5080 has 16 GB GDDR7 at 1875 MHz (30 Gbps effective) on a 256-bit bus for 960.0 GB/s.

Compute units scale accordingly: the W6600M has 1,792 shading units, 112 TMUs, 64 ROPs, and 28 RT cores, with no tensor cores. The RTX 5080 has 10,752 shading units, 336 TMUs, 112 ROPs, 84 RT cores, and 336 tensor cores. The RTX 5080’s FP32 throughput is 56.28 TFLOPS versus 7.290 TFLOPS for the W6600M. The RTX 5080 is a dual-slot card measuring 304 mm x 137 mm x 40 mm, whereas the W6600M is an IGP with no dimensions listed. The RTX 5080 also uses PCIe 5.0 x16 and has 1x HDMI 2.1b and 3x DisplayPort 2.1b outputs, while the W6600M uses PCIe 4.0 x16 and has portable-device-dependent outputs.

Architecture Differences

The W6600M is built on RDNA 2.0, AMD’s architecture that introduced hardware ray tracing to Radeon parts, with 28 RT cores. It is fabricated on TSMC’s 7 nm node. The RTX 5080 is built on Blackwell 2.0, NVIDIA’s latest architecture, which includes 84 RT cores and 336 tensor cores for AI acceleration. It is fabricated on TSMC’s 5 nm node.

The RDNA 2.0 architecture in the W6600M uses a 2:1 FP16 ratio, meaning FP16 throughput is double FP32. The Blackwell 2.0 architecture in the RTX 5080 uses a 1:1 ratio, where FP16 equals FP32 at 56.28 TFLOPS. This makes the RTX 5080 far more efficient for mixed-precision workloads. Both support DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4, so API compatibility is identical.

The W6600M is part of the Radeon Pro Mobile (W6x00M) generation, succeeding FirePro Mobile, and is now end-of-life. The RTX 5080 is part of the GeForce 50-series, succeeding GeForce 40, and is active with a successor (GeForce 60) already listed. The RTX 5080’s 5 nm process and higher transistor density (120.6M / mm²) reflect a newer, denser design. The W6600M’s 90 W TDP is a fraction of the RTX 5080’s 360 W, reflecting its mobile, integrated nature versus the desktop dual-slot card with a 16-pin connector and 750 W suggested PSU.

The Verdict

Choose the AMD Radeon Pro W6600M if you need a mobile workstation GPU with a 90 W TDP and no power connectors. It is an IGP with a 7 nm RDNA 2.0 design, 8 GB GDDR6, and a 224.0 GB/s bandwidth. Its average benchmark score of 61,896 and 89th percentile ranking show it is a capable part for its class, sitting close to the AMD Radeon 8050S (delta -0.3%) and ahead of the NVIDIA GeForce RTX 4090 (delta 2.6%). It is end-of-life, so it is not a future-proof choice, but for a portable professional workload, it is adequate.

Choose the NVIDIA GeForce RTX 5080 if you need maximum desktop performance. It wins both head-to-head benchmarks with 76.2% and 73.5% leads in OpenCL and Vulkan, respectively. It offers 16 GB GDDR7, 960.0 GB/s bandwidth, 56.28 TFLOPS FP32, and 336 tensor cores for AI work. Its 360 W TDP and dual-slot form factor demand a 750 W PSU and a full-size PCIe 5.0 slot. Its launch MSRP is 999 USD. Despite its lower average benchmark score (56,083) and 87th percentile ranking — both skewed by anomalous Passmark DirectX results — the RTX 5080 is the superior performer in every meaningful head-to-head comparison. The RTX 5080’s nearest rivals include the AMD Radeon 8060S (delta 0.6%) and AMD Radeon RX 9070 GRE (delta -2.2%), showing it is competitive within its own tier. The verdict is straightforward: the RTX 5080 is for those who prioritize raw power, while the W6600M is for those who prioritize portability and low power draw.