AMD Radeon PRO W6600 vs NVIDIA RTX A4500 Mobile Comparison

The NVIDIA RTX A4500 Mobile and AMD Radeon PRO W6600 are both end-of-life professional mobile and desktop workstation GPUs, respectively, but they target different segments with distinct architectural approaches. The data shows a clear split in benchmark performance: the NVIDIA part dominates OpenCL compute, while the AMD card edges out a win in Vulkan. The RTX A4500 Mobile averages a benchmark score of 91,134, placing it in the 93rd percentile of all GPUs, while the Radeon PRO W6600 averages 81,995, sitting just behind in the 92nd percentile. This 11.1% gap in average score, however, only tells part of the story, as the individual test results reveal nuanced strengths.

Head-to-Head Benchmarks

The most decisive result is in the Geekbench OpenCL test, where the NVIDIA RTX A4500 Mobile scores 105,307 against the AMD Radeon PRO W6600’s 73,514. That is a 43.2% advantage for the NVIDIA part, a massive margin that underscores its compute-heavy design. This result aligns with the A4500 Mobile’s raw specifications: it carries 5,888 shading units, 184 texture mapping units, and 96 ROPs, compared to the W6600’s 1,792 shading units, 112 TMUs, and 64 ROPs. The FP32 throughput reflects this chasm, with the NVIDIA card delivering 17.66 TFLOPS versus the AMD card’s 9.247 TFLOPS. In purely arithmetic throughput, the A4500 Mobile is roughly 91% faster, and the OpenCL benchmark confirms that lead in a real-world compute workload.

However, the AMD Radeon PRO W6600 strikes back in the Geekbench Vulkan test. Here, the AMD card scores 78,428, edging out the NVIDIA RTX A4500 Mobile’s 76,960, a 1.9% difference. While narrow, this win is significant because it shows the RDNA 2.0 architecture’s efficiency in graphics-oriented, driver-level workloads. The W6600’s higher clock speeds play a role: its base clock is 2,331 MHz and boost reaches 2,580 MHz, far above the A4500 Mobile’s 930 MHz base and 1,500 MHz boost. Even with fewer cores, the AMD card’s superior frequency helps it close the gap in Vulkan, where the workload may be more latency-sensitive than purely throughput-driven. The pixel rate also favors AMD at 165.1 GPixel/s versus NVIDIA’s 144.0 GPixel/s, and the texture rate is similarly close, with AMD at 289.0 GTexel/s and NVIDIA at 276.0 GTexel/s.

Looking at the broader competitive context, the RTX A4500 Mobile’s average score of 91,134 places it 4.2% ahead of the NVIDIA Quadro GP100 (87,445) and 4.6% ahead of the AMD Radeon PRO W7600 (87,108). It trails the desktop NVIDIA RTX A4500 by a mere 0.6% (91,671) and the AMD Radeon Instinct MI60 by 1.4% (92,466), indicating that the mobile variant sacrifices almost nothing in raw compute versus its desktop sibling. Conversely, the Radeon PRO W6600’s average of 81,995 sits 1.3% above the AMD Radeon Pro Vega 64X (80,959) and 2.7% above the NVIDIA GeForce RTX 5090 (79,842). This suggests the W6600 is a solid mid-range performer, but it cannot match the A4500 Mobile’s top-tier compute output.

The wins are split one apiece, but the magnitude of the NVIDIA victory in OpenCL dwarfs the AMD victory in Vulkan. A 43.2% lead in one test versus a 1.9% lead in another indicates that the A4500 Mobile is the superior overall performer, particularly for compute-heavy tasks. The Vulkan result for AMD is notable for showing that architecture and clocks can offset core counts, but it does not change the fact that the NVIDIA part is substantially faster in the aggregate.

FAQ

Q: Which GPU has the higher average benchmark score?

A: The NVIDIA RTX A4500 Mobile has an average benchmark score of 91,134, which is 11.1% higher than the AMD Radeon PRO W6600’s 81,995. The NVIDIA part also ranks in the 93rd percentile of all GPUs, while the AMD card ranks in the 92nd percentile.

Q: How do the two GPUs compare in OpenCL performance?

A: In the Geekbench OpenCL test, the NVIDIA RTX A4500 Mobile scores 105,307, which is 43.2% higher than the AMD Radeon PRO W6600’s 73,514. This is the largest performance gap between the two in any benchmark.

Q: Does the AMD Radeon PRO W6600 win any benchmark against the NVIDIA RTX A4500 Mobile?

A: Yes, the AMD Radeon PRO W6600 wins the Geekbench Vulkan test with a score of 78,428, compared to the NVIDIA RTX A4500 Mobile’s 76,960, a 1.9% difference. This is the only head-to-head test where AMD comes out ahead.

Q: What is the memory configuration difference between the two?

A: The NVIDIA RTX A4500 Mobile features 16 GB of GDDR6 memory on a 256-bit bus, providing 512.0 GB/s of bandwidth. The AMD Radeon PRO W6600 has 8 GB of GDDR6 memory on a 128-bit bus, offering 224.0 GB/s of bandwidth.

Q: Which GPU has a higher transistor density?

A: The AMD Radeon PRO W6600 has a higher transistor density at 46.7M transistors per mm², despite having fewer total transistors. The NVIDIA RTX A4500 Mobile has a density of 44.4M / mm².

Q: Are both GPUs compatible with DirectX 12 Ultimate?

A: Yes, both the NVIDIA RTX A4500 Mobile and the AMD Radeon PRO W6600 support DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4, according to the API specifications.

The Verdict

For users prioritizing raw compute throughput, the NVIDIA RTX A4500 Mobile is the clear choice. Its 43.2% lead in OpenCL and its 11.1% higher average benchmark score demonstrate that it is in a different performance class for arithmetic-heavy tasks. The 16 GB memory capacity and 512.0 GB/s bandwidth further reinforce its suitability for large datasets and complex simulations. The data suggests that the A4500 Mobile is positioned near the top of the professional GPU hierarchy, sitting within 1.4% of the AMD Radeon Instinct MI60 and only 0.6% behind the desktop NVIDIA RTX A4500.

The AMD Radeon PRO W6600, on the other hand, deserves consideration for graphics-centric professional workloads where Vulkan performance is critical. Its 1.9% win in the Vulkan benchmark, combined with higher base and boost clocks (2,331 MHz and 2,580 MHz versus 930 MHz and 1,500 MHz), suggests that it can handle real-time rendering tasks with relative efficiency. Its 100 W TDP versus the A4500 Mobile’s 140 W also indicates lower power draw, though the A4500 Mobile’s power connector is listed as "None" while the W6600 requires a single 6-pin connector.

The verdict is straightforward: pick the NVIDIA RTX A4500 Mobile for compute-heavy professional work, as its OpenCL dominance and larger memory pool make it the superior all-around performer. Pick the AMD Radeon PRO W6600 if Vulkan-specific performance and a lower power envelope are the primary concerns, as its benchmark win and efficiency profile offer a viable alternative.

Specification Differences

The two GPUs differ across nearly every core specification. The NVIDIA RTX A4500 Mobile is built on the GA104 chip with an 8 nm process from Samsung, while the AMD Radeon PRO W6600 uses the Navi 23 chip on a 7 nm process from TSMC. The NVIDIA part has a transistor count of 17,400 million and a die size of 392 mm², whereas the AMD part has 11,060 million transistors on a 237 mm² die. Clock speeds diverge sharply: the A4500 Mobile runs at 930 MHz base and 1,500 MHz boost, while the W6600 runs at 2,331 MHz base and 2,580 MHz boost. Memory configurations also differ, with the NVIDIA card offering 16 GB at 16 Gbps effective and the AMD card offering 8 GB at 14 Gbps effective. The memory bus width is 256-bit for NVIDIA and 128-bit for AMD, leading to bandwidths of 512.0 GB/s and 224.0 GB/s, respectively.

The shading unit count is 5,888 for NVIDIA versus 1,792 for AMD, and the TMU count is 184 versus 112, with ROPs at 96 versus 64. The RT core counts are 46 for NVIDIA and 28 for AMD, and the NVIDIA card includes 184 tensor cores, while the AMD card has none. Pixel rate favors AMD at 165.1 GPixel/s versus NVIDIA’s 144.0 GPixel/s, and texture rate is 289.0 GTexel/s for AMD versus 276.0 GTexel/s for NVIDIA. FP32 performance is 17.66 TFLOPS for NVIDIA and 9.247 TFLOPS for AMD, but FP16 performance is 17.66 TFLOPS (1:1) for NVIDIA and 18.49 TFLOPS (2:1) for AMD. Power consumption differs, with the NVIDIA card at 140 W and the AMD card at 100 W. The bus interface is PCIe 4.0 x16 for NVIDIA and PCIe 4.0 x8 for AMD, and display outputs are portable-device-dependent for NVIDIA versus 4x DisplayPort 1.4a for AMD.

Architecture Differences

The architectural foundations of these two GPUs are fundamentally different. The NVIDIA RTX A4500 Mobile is based on the Ampere architecture, using the GA104 chip, while the AMD Radeon PRO W6600 uses the RDNA 2.0 architecture with the Navi 23 chip. The NVIDIA generation is designated "Ampere-MW (Ax000)" with a predecessor of "Quadro Turing-M" and a successor of "Ada-MW," while the AMD generation is "Radeon Pro Navi (Navi II Series)" with a predecessor of "Radeon Pro Vega" and no listed successor. The process nodes differ, with NVIDIA using an 8 nm Samsung process and AMD using a 7 nm TSMC process. The transistor density is slightly higher on the AMD chip at 46.7M / mm² versus NVIDIA’s 44.4M / mm², despite the NVIDIA chip having more total transistors.

Feature-wise, the NVIDIA card integrates 184 tensor cores, which are absent from the AMD card, and has 46 RT cores against AMD’s 28. The FP16 compute ratio also highlights a key difference: NVIDIA achieves FP16 at a 1:1 ratio with FP32 (17.66 TFLOPS each), while AMD doubles FP16 throughput to 18.49 TFLOPS at a 2:1 ratio. This suggests NVIDIA’s tensor core design is optimized for mixed-precision work, while AMD’s RDNA 2.0 architecture prioritizes higher FP16 throughput for specific workloads. The memory clock rates show NVIDIA at 2000 MHz with 16 Gbps effective and AMD at 1750 MHz with 14 Gbps effective. The slot width is single-slot for AMD, while no slot width is listed for NVIDIA, and the AMD card has a length of 241 mm (9.5 inches), while NVIDIA’s dimensions are not provided. The release timeline also differs, with the NVIDIA card launching on 2022-03-21 and the AMD card on 2021-06-07.