AMD Radeon PRO W6400 vs AMD Radeon RX 7650 GRE Comparison

Head-to-Head Benchmarks

The database records only one shared benchmark between the AMD Radeon RX 7650 GRE and the AMD Radeon PRO W6400: Geekbench OpenCL. The RX 7650 GRE scores 83,109, while the PRO W6400 scores 35,027. That is a 137.3% advantage for the RX 7650 GRE, meaning it delivers more than double the raw compute throughput in this OpenCL workload. This is a decisive gap, not a marginal one, and it sets the tone for the rest of the comparison.

Looking at the broader database averages, the RX 7650 GRE holds an average benchmark score of 42,723 across all recorded tests. The PRO W6400 sits at 37,157. The RX 7650 GRE is roughly 15% ahead on aggregate, though the single head-to-head result shows a far larger lead than the averages suggest. The reason is that the PRO W6400's average is buoyed by a Vulkan result of 39,286, a test the RX 7650 GRE does not appear in. In the only direct comparison available, the RX 7650 GRE is overwhelmingly faster.

The percentile ranks tell a similar story. The RX 7650 GRE sits in the 83rd percentile of all GPUs in the database, while the PRO W6400 sits in the 80th. Despite the massive OpenCL delta, the two cards are only three percentile points apart overall. This is because the PRO W6400's Vulkan score is comparatively strong for its class, and the RX 7650 GRE's percentile is dragged down by the fact that its Steel Nomad DX12 result of 2,336 is a relatively modest score for a card in its tier.

The nearest rivals for each card help contextualize their positions. The RX 7650 GRE's closest competitor is the NVIDIA GeForce RTX 4070 SUPER, which averages 43,223, just 1.2% higher. The PRO W6400's nearest rival is the AMD Radeon RX Vega 56 at 37,507, a 0.9% gap. In other words, the PRO W6400 is competitive with a much older flagship, while the RX 7650 GRE is trading blows with a modern high-end NVIDIA card. The RX 7650 GRE also trails the NVIDIA Quadro M6000 24 GB by 1.2% and the NVIDIA GeForce RTX 5050 Mobile by 1.3%, showing it sits right at the edge of a cluster of similarly performing GPUs. The PRO W6400 is 1.3% behind both the NVIDIA Tesla P4 and the NVIDIA GeForce RTX 4070, but 1.7% ahead of the NVIDIA GeForce GTX TITAN X.

Architecture Differences

The RX 7650 GRE is built on RDNA 3.0 and uses the Navi 33 chip, codenamed Hotpink Bonefish. The PRO W6400 uses RDNA 2.0 with the Navi 24 chip. Both are fabricated on TSMC's 6 nm process, so the node is not a differentiator. The transistor counts, however, are very different. The RX 7650 GRE packs 13,300 million transistors on a 204 mm² die, giving a transistor density of 65.2 million per mm². The PRO W6400 has 5,400 million transistors on a 107 mm² die, at 50.5 million per mm². The RX 7650 GRE has more than twice the transistor budget and a denser layout.

The compute resources differ sharply. The RX 7650 GRE has 2,048 shading units, 128 texture mapping units, and 64 raster operation pipelines. The PRO W6400 has 768 shading units, 48 TMUs, and 32 ROPs. The RX 7650 GRE also has 32 ray tracing cores versus 12 on the PRO W6400. Neither card has dedicated tensor cores, so AI acceleration is not a differentiator here.

Memory architecture is another major split. The RX 7650 GRE uses 8 GB of GDDR6 on a 128-bit bus, delivering 288.0 GB/s of bandwidth. The PRO W6400 has 4 GB of GDDR6 on a 64-bit bus, at 128.0 GB/s. The RX 7650 GRE has double the VRAM capacity and more than double the memory bandwidth. Its memory clock runs at 2250 MHz (18 Gbps effective), while the PRO W6400 runs at 2000 MHz (16 Gbps effective).

Clock speeds show an interesting inversion. The PRO W6400 has a higher base clock at 2039 MHz versus 1720 MHz on the RX 7650 GRE. The boost clocks are closer: 2321 MHz on the PRO W6400 versus 2695 MHz on the RX 7650 GRE. The RX 7650 GRE also has a game clock of 2350 MHz, a figure the PRO W6400 does not list. Despite the higher base clock on the PRO W6400, the RX 7650 GRE's massive shader count and memory bandwidth overwhelm it in throughput.

The RX 7650 GRE belongs to the Radeon RX 7000 series, specifically the Navi III generation, with a release date of February 6, 2025. The PRO W6400 is from the Radeon Pro Navi generation and was released on January 18, 2022. The PRO W6400 is marked as end-of-life, while the RX 7650 GRE is still active in production. The RX 7650 GRE's predecessor is Navi II and its successor is Navi IV. The PRO W6400's predecessor is the Radeon Pro Vega, and it has no recorded successor.

The Verdict

The data is unambiguous. The RX 7650 GRE is the faster card by a wide margin in the only shared benchmark, and its hardware specifications support that result. It has more than double the shading units, more than double the memory bandwidth, more than double the VRAM, and a newer architecture. The 137.3% OpenCL lead is consistent with the raw resource advantage, not an anomaly.

The PRO W6400 is not without merit, but its merits are not about raw performance. It consumes 50 W versus 170 W, it is a single-slot card with no power connectors, and it requires only a 250 W power supply versus 450 W. It is a low-profile, low-power option for systems where space and thermal envelope matter more than frame rates or compute throughput. Its higher base clock of 2039 MHz suggests it can hold reasonable performance at lower loads, but it simply does not have the execution resources to compete with the RX 7650 GRE in heavy workloads.

The RX 7650 GRE also has a significantly better standing among all GPUs. Its average benchmark score of 42,723 places it within 1.2% of the NVIDIA GeForce RTX 4070 SUPER, a high-end card. The PRO W6400's average of 37,157 is within 0.9% of the RX Vega 56, a card from the previous generation. The RX 7650 GRE is competing in a higher performance tier.

The PRO W6400's Vulkan score of 39,286 is worth noting. It is higher than its OpenCL score of 35,027, indicating the card is better optimized for Vulkan workloads. This gives it a niche in specific professional applications that favor Vulkan. But even that 39,286 score is far below the RX 7650 GRE's OpenCL result of 83,109, and the RX 7650 GRE does not have a recorded Vulkan score to compare directly.

For most buyers, the RX 7650 GRE is the clear choice on performance. The PRO W6400 only makes sense for a narrow set of use cases where its low power draw and single-slot form factor are critical constraints. The RX 7650 GRE was released with a launch MSRP of 279 USD. The PRO W6400 has no recorded launch MSRP.

Specification Differences

The two cards differ in nearly every meaningful specification. The RX 7650 GRE uses the Navi 33 chip on RDNA 3.0, while the PRO W6400 uses Navi 24 on RDNA 2.0. The RX 7650 GRE has 13,300 million transistors on a 204 mm² die; the PRO W6400 has 5,400 million on 107 mm². Transistor density is 65.2M per mm² versus 50.5M per mm².

Base clock: the RX 7650 GRE runs at 1720 MHz, the PRO W6400 at 2039 MHz. Boost clock: 2695 MHz versus 2321 MHz. The RX 7650 GRE has a game clock of 2350 MHz; the PRO W6400 has none listed. Memory clock: 2250 MHz (18 Gbps effective) versus 2000 MHz (16 Gbps effective).

Memory: 8 GB versus 4 GB GDDR6. Bus width: 128-bit versus 64-bit. Bandwidth: 288.0 GB/s versus 128.0 GB/s. Shading units: 2,048 versus 768. TMUs: 128 versus 48. ROPs: 64 versus 32. Ray tracing cores: 32 versus 12.

Pixel rate: 172.5 GPixel/s versus 74.27 GPixel/s. Texture rate: 345.0 GTexel/s versus 111.4 GTexel/s. FP32: 22.08 TFLOPS versus 3.565 TFLOPS. FP16: 22.08 TFLOPS (1:1) versus 7.130 TFLOPS (2:1). TDP: 170 W versus 50 W.

Slot width: dual-slot versus single-slot. Power connectors: 1x 8-pin versus none. Suggested PSU: 450 W versus 250 W. Bus interface: PCIe 4.0 x8 versus PCIe 4.0 x4.

Display outputs: the RX 7650 GRE has 1x HDMI 2.1a and 3x DisplayPort 2.1. The PRO W6400 has 2x DisplayPort 1.4a. Dimensions: the RX 7650 GRE is 204 mm long and 115 mm tall; the PRO W6400 has no recorded dimensions.

Both support DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4.

FAQ

Q: Which card is faster in OpenCL?

A: The AMD Radeon RX 7650 GRE scores 83,109 in Geekbench OpenCL, while the AMD Radeon PRO W6400 scores 35,027. The RX 7650 GRE is 137.3% faster in this test.

Q: How much VRAM does each card have?

A: The RX 7650 GRE has 8 GB of GDDR6 on a 128-bit bus with 288.0 GB/s bandwidth. The PRO W6400 has 4 GB of GDDR6 on a 64-bit bus with 128.0 GB/s bandwidth.

Q: What are the power requirements?

A: The RX 7650 GRE has a TDP of 170 W and requires a 450 W power supply with a 1x 8-pin connector. The PRO W6400 has a TDP of 50 W, requires a 250 W power supply, and needs no power connectors.

Q: Which card has a better standing among all GPUs?

A: The RX 7650 GRE is in the 83rd percentile with an average benchmark score of 42,723. The PRO W6400 is in the 80th percentile with an average score of 37,157.

Q: Are both cards from the same architecture generation?

A: No. The RX 7650 GRE uses RDNA 3.0 with the Navi 33 chip. The PRO W6400 uses RDNA 2.0 with the Navi 24 chip. Both are on TSMC's 6 nm process.

Q: What is the production status of each card?

A: The RX 7650 GRE is listed as active and was released on February 6, 2025. The PRO W6400 is listed as end-of-life and was released on January 18, 2022.

Where Each One Wins

The RX 7650 GRE wins on raw compute, memory capacity, memory bandwidth, and modern feature support. Its 22.08 TFLOPS of FP32 performance is more than six times the PRO W6400's 3.565 TFLOPS. Its 288.0 GB/s bandwidth is more than double. Its 8 GB VRAM is double. Its 32 ray tracing cores versus 12 give it a clear edge in any ray-traced workload. Its DisplayPort 2.1 outputs are newer than the PRO W6400's DisplayPort 1.4a. For gaming, content creation, or any GPU-accelerated compute task, the RX 7650 GRE is the stronger card.

The PRO W6400 wins on power efficiency and physical footprint. At 50 W, it consumes less than a third of the RX 7650 GRE's 170 W. It is a single-slot card with no power connectors, while the RX 7650 GRE is dual-slot with a 1x 8-pin connector. The PRO W6400's suggested PSU of 250 W means it can drop into systems with small power supplies. Its higher base clock of 2039 MHz hints at decent low-load responsiveness, and its Vulkan score of 39,286 shows it handles Vulkan workloads better than OpenCL. For a workstation that needs modest graphics acceleration in a tight chassis with minimal power draw, the PRO W6400 is the practical pick.

The benchmark data does not show any test where the PRO W6400 beats the RX 7650 GRE. The only shared test is OpenCL, and the RX 7650 GRE dominates it. The PRO W6400's wins are entirely in the categories of power, size, and system integration, not performance. The RX 7650 GRE is the card to choose when performance matters. The PRO W6400 is the card to choose when the system constraints matter more than the score.