AMD Radeon Pro Vega 64X vs NVIDIA GeForce RTX 4080 SUPER Comparison

Head-to-Head Benchmarks

The recorded data contains a single direct comparison between the AMD Radeon Pro Vega 64X and the NVIDIA GeForce RTX 4080 SUPER. In the Geekbench OpenCL test, the NVIDIA card delivers a score of 219,065, while the AMD card scores 78,467. The delta is substantial: the RTX 4080 SUPER finishes 64.2% ahead, which is a decisive margin in raw compute throughput.

Contextualizing the AMD Radeon Pro Vega 64X within the database, its average benchmark score of 80,959 places it in the 92nd percentile of all GPUs. Its nearest rivals in the database include the AMD Radeon PRO W6600, which averages 81,995 (a 1.3% difference, making the Vega 64X slightly behind), and the NVIDIA GeForce RTX 5090 at 79,842, a 1.4% gap in favor of the Vega 64X. The NVIDIA Tesla P100 PCIe 16 GB sits at 79,605 (1.7% behind the Vega 64X), and the Tesla P100 PCIe 12 GB at 79,396 (2% behind). These figures show the Vega 64X is highly competitive within its own performance tier, despite being an older design.

The NVIDIA GeForce RTX 4080 SUPER, by contrast, has an average benchmark score of 54,209, placing it in the 86th percentile. Its nearest rivals are tightly clustered: the RTX 4080 scores 54,247 (0.1% difference), the AMD Radeon Pro W5700X scores 54,828 (1.1% ahead), the AMD Radeon RX 6750 GRE 12 GB scores 55,698 (2.7% ahead), and the AMD Radeon 8060S scores 55,757 (2.8% ahead). This clustering indicates that the RTX 4080 SUPER's average score is pulled down by a broader set of workloads, including some that are not compute-heavy. Its Geekbench OpenCL result, however, is far above the Vega 64X's, and it also posts a strong Geekbench Vulkan score of 260,075 and a 3DMark Steel Nomad DX12 score of 6,600.

The average benchmark score comparison is interesting because the Vega 64X's average (80,959) is actually higher than the RTX 4080 SUPER's average (54,209). This is largely due to the test suite composition: the Vega 64X has only two recorded benchmarks (Geekbench Metal at 83,450 and Geekbench OpenCL at 78,467), both of which are compute-oriented. The RTX 4080 SUPER has many more recorded tests, including several Passmark entries (DirectX 9 at 381, DirectX 10 at 193, DirectX 11 at 301, DirectX 12 at 134, G2D at 1,270, G3D at 34,245, and GPU compute at 19,822). These Passmark scores vary widely and drag down the average. The direct head-to-head in OpenCL is unambiguous, though: NVIDIA wins by a wide margin.

The Verdict

From the recorded data, the NVIDIA GeForce RTX 4080 SUPER is the clear winner in the one benchmark where both cards appear: Geekbench OpenCL, with a 64.2% lead. The NVIDIA card also shows a much broader benchmark profile, with Vulkan support (260,075 in Geekbench Vulkan) and a dedicated DirectX 12 ray-traced workload (6,600 in 3DMark Steel Nomad DX12). The AMD Radeon Pro Vega 64X has no recorded ray-tracing or Vulkan scores in the database.

The AMD card's strengths lie elsewhere. Its average benchmark score of 80,959 exceeds the NVIDIA card's average of 54,209, and its percentile rank of 92 is higher than the RTX 4080 SUPER's 86. In the database, the Vega 64X is positioned alongside professional workstation cards like the AMD Radeon PRO W6600 (81,995) and NVIDIA Tesla P100 variants (79,605 and 79,396). The RTX 4080 SUPER, meanwhile, sits near gaming and workstation cards like the RTX 4080 (54,247) and the AMD Radeon Pro W5700X (54,828).

Who should pick which, strictly from the data: if the workload is OpenCL compute, the RTX 4080 SUPER is massively ahead. If the workload is Metal-based or relies on the broader set of compute tests that contribute to the Vega 64X's higher average, the AMD card looks better in aggregate. The RTX 4080 SUPER offers a more complete feature set in terms of API support (DirectX 12 Ultimate, Vulkan 1.4) and has a much larger shading unit count (10,240 vs. 4,096), but the Vega 64X holds its own in the specific compute benchmarks recorded.

Architecture Differences

The two cards come from different architectural eras. The AMD Radeon Pro Vega 64X uses the Vega 10 chip built on GCN 5.0 architecture, fabricated on a 14 nm process at GlobalFoundries. It packs 12,500 million transistors on a 495 mm² die, giving a transistor density of 25.3 million per mm². The NVIDIA GeForce RTX 4080 SUPER uses the AD103 chip based on Ada Lovelace architecture, built on a 5 nm process at TSMC. It contains 45,900 million transistors on a 379 mm² die, a transistor density of 121.1 million per mm².

The clock behavior is also very different. The Vega 64X has a base clock of 1250 MHz and a boost clock of 1468 MHz, with memory running at 1000 MHz (2 Gbps effective). The RTX 4080 SUPER has a base clock of 2295 MHz and a boost clock of 2550 MHz, with memory at 1438 MHz (23 Gbps effective). The NVIDIA card runs substantially faster out of the box.

Memory configurations are comparable in capacity but not in technology. Both cards have 16 GB of memory. The Vega 64X uses HBM2 on a 2048-bit bus with 512.0 GB/s of bandwidth. The RTX 4080 SUPER uses GDDR6X on a 256-bit bus with 736.3 GB/s of bandwidth. The NVIDIA card has 44% more memory bandwidth despite the narrower bus.

Compute resources differ massively. The Vega 64X has 4,096 shading units, 256 TMUs, and 64 ROPs. It has no dedicated ray-tracing cores or tensor cores. The RTX 4080 SUPER has 10,240 shading units, 320 TMUs, and 112 ROPs, plus 80 ray-tracing cores and 320 tensor cores. Pixel rate is 93.95 GPixel/s for the AMD card and 285.6 GPixel/s for the NVIDIA card. Texture rate is 375.8 GTexel/s versus 816.0 GTexel/s. FP32 throughput is 12.03 TFLOPS versus 52.22 TFLOPS. The NVIDIA card is roughly 4.3 times higher in FP32.

FP16 performance is notable: the Vega 64X achieves 24.05 TFLOPS via a 2:1 ratio, while the RTX 4080 SUPER achieves 52.22 TFLOPS at a 1:1 ratio. The NVIDIA card's FP16 is identical to its FP32, whereas the AMD card doubles its rate when using packed math.

Power and physical design are also distinct. The Vega 64X has a TDP of 250 W, no power connectors (it is an integrated GPU package, IGP, with a slot width of IGP), and a PCIe 3.0 x16 interface. The RTX 4080 SUPER has a TDP of 320 W, requires a single 16-pin power connector, has a suggested PSU of 700 W, is a triple-slot card, and uses PCIe 4.0 x16. Its dimensions are 310 mm in length, 140 mm in height, and 61 mm in width.

API support differs as well. The Vega 64X supports DirectX 12 (12_1), OpenGL 4.6, and Vulkan 1.3. The RTX 4080 SUPER supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4. Display outputs on the Vega 64X are listed as portable device dependent, while the RTX 4080 SUPER has 1x HDMI 2.1 and 3x DisplayPort 1.4a.

FAQ

Q: Which card has the higher average benchmark score in the database?

A: The AMD Radeon Pro Vega 64X has an average benchmark score of 80,959, while the NVIDIA GeForce RTX 4080 SUPER has an average of 54,209.

Q: How much faster is the RTX 4080 SUPER in Geekbench OpenCL?

A: The RTX 4080 SUPER scores 219,065 versus 78,467 for the Vega 64X, a 64.2% advantage for the NVIDIA card.

Q: Do both cards support the same DirectX version?

A: No. The Vega 64X supports DirectX 12 (12_1), while the RTX 4080 SUPER supports DirectX 12 Ultimate (12_2).

Q: What is the memory bandwidth of each card?

A: The Vega 64X has 512.0 GB/s of bandwidth using HBM2 on a 2048-bit bus. The RTX 4080 SUPER has 736.3 GB/s using GDDR6X on a 256-bit bus.

Q: Which card has ray-tracing cores?

A: Only the RTX 4080 SUPER has ray-tracing cores (80). The Vega 64X has no ray-tracing cores and no tensor cores.

Q: What are the production statuses of these cards?

A: Both are end-of-life. The Vega 64X was released in March 2019, and the RTX 4080 SUPER was released in January 2024.

Where Each One Wins

In OpenCL compute, the NVIDIA GeForce RTX 4080 SUPER wins decisively. The 64.2% margin in the head-to-head test is the only direct comparison available, and it is not close. The RTX 4080 SUPER also wins on raw specifications: higher FP32 (52.22 TFLOPS), higher texture rate (816.0 GTexel/s), higher pixel rate (285.6 GPixel/s), more shading units (10,240), and more memory bandwidth (736.3 GB/s). It is the only card with ray-tracing cores and tensor cores, and it supports the newer DirectX 12 Ultimate and Vulkan 1.4 APIs. For any workload that leverages these features, the NVIDIA card is the clear choice.

The AMD Radeon Pro Vega 64X wins in the aggregate database average, 80,959 versus 54,209, and holds a higher percentile rank (92nd vs. 86th). Its nearest rivals are professional compute cards, and its Geekbench Metal score of 83,450 is its strongest recorded result. The Vega 64X also has a lower TDP (250 W vs. 320 W) and does not require external power connectors, making it more suitable for integrated or space-constrained systems. Its HBM2 memory on a 2048-bit bus provides a different memory profile compared to GDDR6X, though bandwidth is lower.

For users prioritizing compute workloads that are heavily weighted in the database's average (such as Metal-based tasks or the specific OpenCL implementation used), the Vega 64X may appear more attractive in aggregate. For users prioritizing modern gaming features, ray tracing, Vulkan performance, and raw FP32 throughput, the RTX 4080 SUPER is the stronger option. The recorded data does not include gaming-specific benchmarks for the Vega 64X, so any assessment of gaming performance for that card is not possible from this database. The RTX 4080 SUPER has multiple Passmark DirectX scores (9 through 12), which indicate broad DirectX coverage, but the Vega 64X has no such entries.

The launch MSRP of the RTX 4080 SUPER is 999 USD. The Vega 64X has no recorded launch MSRP in the database.