AMD Radeon Pro Vega 64X vs AMD Radeon RX 6650M XT Comparison

The AMD Radeon Pro Vega 64X and the AMD Radeon RX 6650M XT represent two distinct approaches to GPU design within AMD’s lineup: a high-power workstation-oriented chip versus a mobile-optimized part. Benchmark data places them at nearly the same performance level, yet their architectural and specification differences are substantial. The Pro Vega 64X holds a 92nd percentile ranking among all GPUs, while the RX 6650M XT sits just one point lower at the 91st percentile. Their average benchmark scores are separated by only 4,055 points, a margin that translates into a 2% difference in the single shared test.

Head-to-Head Benchmarks

The only direct comparison available is the Geekbench OpenCL test, and the results are remarkably close. The AMD Radeon Pro Vega 64X scores 78,467, while the AMD Radeon RX 6650M XT scores 76,904. This gives the Pro Vega 64X a 2% lead, a relatively narrow margin that falls within typical run-to-run variance for such workloads. In terms of their position among rivals, the Pro Vega 64X’s average score of 80,959 puts it 1.3% ahead of the AMD Radeon PRO W6600 (81,995) and 1.4% behind the NVIDIA GeForce RTX 5090 (79,842). The RX 6650M XT’s average of 76,904 places it 1% behind the NVIDIA GeForce RTX 5090 D (77,712) and 2.6% behind the AMD Radeon RX 6850M XT (78,940).

Looking at the delta percentages against shared rivals reveals a consistent pattern. The Pro Vega 64X is 1.7% ahead of the NVIDIA Tesla P100 PCIe 16 GB (79,605) and 2% ahead of the NVIDIA Tesla P100 PCIe 12 GB (79,396). The RX 6650M XT trails the same two cards by 3.4% and 3.1%, respectively. This means the Pro Vega 64X’s advantage over the RX 6650M XT is roughly equivalent to the performance gap between the two Tesla P100 variants when compared to the mobile card. The data suggests that while the RX 6650M XT is competitive, it consistently sits slightly lower than the Pro Vega 64X across comparable reference points.

The Pro Vega 64X also has an additional benchmark result that the RX 6650M XT lacks: a Geekbench Metal score of 83,450. While this cannot be directly compared, it contributes to the Pro Vega 64X’s higher average score of 80,959 versus 76,904 for its rival. The OpenCL result alone would give the Pro Vega 64X a 2.03% lead, but the inclusion of the Metal score in the average widens the overall gap to approximately 5.3%. This is worth noting because the Metal benchmark often favors different hardware characteristics than OpenCL, suggesting the Pro Vega 64X has a broader performance profile across different compute APIs.

The Verdict

From the benchmark data alone, the AMD Radeon Pro Vega 64X is the faster card. It wins the only head-to-head test, holds a higher average score, and ranks higher in the overall percentile distribution. The 2% OpenCL lead is modest, but the additional Metal score and the better performance against shared rivals like the Tesla P100 cards reinforce its position. For users who prioritize raw compute performance in OpenCL or Metal workloads, the Pro Vega 64X is the clear choice based on the numbers.

However, the RX 6650M XT is not without its merits. It achieves 91% of the Pro Vega 64X’s performance level while being a mobile part with a significantly lower power envelope. The data shows it is within 1% of the NVIDIA GeForce RTX 5090 D, a desktop-class GPU, which is impressive for a mobile chip. Users who need a portable solution with near-desktop performance would find the RX 6650M XT adequate, provided they accept a small but measurable performance deficit. The Pro Vega 64X, being an integrated part for portable devices as well, does not offer a clear form-factor advantage, but its performance lead is consistent across all available metrics.

There is no scenario in the data where the RX 6650M XT wins a benchmark. The verdict is straightforward: the Pro Vega 64X is the higher-performing GPU, while the RX 6650M XT is a close second that trades a small amount of performance for the efficiency of a newer, smaller process node.

FAQ

Q: Which GPU has the higher average benchmark score?

A: The AMD Radeon Pro Vega 64X has an average benchmark score of 80,959, while the AMD Radeon RX 6650M XT averages 76,904, giving the Pro Vega 64X a lead of approximately 5.3%.

Q: How large is the performance difference in the shared Geekbench OpenCL test?

A: The Pro Vega 64X scores 78,467 versus 76,904 for the RX 6650M XT, a 2% advantage for the Pro Vega 64X.

Q: Does the RX 6650M XT outperform the Pro Vega 64X in any benchmark?

A: No. The RX 6650M XT has zero wins in the head-to-head comparison, while the Pro Vega 64X has one win.

Q: How do these GPUs compare to the NVIDIA Tesla P100 PCIe 12 GB?

A: The Pro Vega 64X is 2% ahead of the Tesla P100 PCIe 12 GB (79,396), while the RX 6650M XT is 3.1% behind the same card.

Q: What is the percentile ranking difference between the two cards?

A: The Pro Vega 64X is in the 92nd percentile of all GPUs, while the RX 6650M XT is in the 91st percentile.

Q: Which GPU has a Geekbench Metal result?

A: Only the AMD Radeon Pro Vega 64X has a Geekbench Metal score, which is 83,450. The RX 6650M XT has no Metal benchmark listed.

Specification Differences

The two GPUs differ significantly in nearly every core specification. The Pro Vega 64X uses 4,096 shading units, 256 texture mapping units, and 64 ROPs. The RX 6650M XT halves the shading units to 2,048 and TMUs to 128, while keeping the same 64 ROPs. In terms of memory, the Pro Vega 64X offers 16 GB of HBM2 on a 2048-bit bus with 512.0 GB/s bandwidth, whereas the RX 6650M XT has 8 GB of GDDR6 on a 128-bit bus with 256.0 GB/s bandwidth. The memory clock also differs: 1000 MHz (2 Gbps effective) for the Pro Vega 64X versus 2000 MHz (16 Gbps effective) for the RX 6650M XT.

Clock speeds show a large divergence. The Pro Vega 64X runs at a base of 1250 MHz and boosts to 1468 MHz, while the RX 6650M XT starts at 2068 MHz, boosts to 2416 MHz, and has a game clock of 2162 MHz. The power consumption reflects this: the Pro Vega 64X is rated at 250 W TDP, while the RX 6650M XT is rated at 120 W TDP. The bus interface differs as well, with the Pro Vega 64X using PCIe 3.0 x16 and the RX 6650M XT using PCIe 4.0 x8. Both are integrated parts with no power connectors and portable-device-dependent display outputs.

The process node and foundry also differ completely. The Pro Vega 64X uses a 14 nm process at GlobalFoundries, while the RX 6650M XT uses a 7 nm process at TSMC. Transistor counts are close (12,500 million vs 11,060 million), but the die size is much smaller for the RX 6650M XT (237 mm² vs 495 mm²), leading to a significantly higher transistor density of 46.7M per mm² versus 25.3M per mm².

Architecture Differences

The architectural divide is fundamental. The Pro Vega 64X is based on the Vega 10 chip using GCN 5.0 architecture, while the RX 6650M XT uses the Navi 23 chip with RDNA 2.0 architecture. This is a generational leap: GCN 5.0 belongs to the Radeon Pro Mac (Vega Series) generation, while RDNA 2.0 is part of the Navi Mobile (RX 6000M) generation. The RX 6650M XT includes 32 ray tracing cores, a feature entirely absent from the Pro Vega 64X, which has no RT cores listed.

The shading and compute capabilities reflect these architectural changes. The Pro Vega 64X delivers 12.03 TFLOPS of FP32 performance and 24.05 TFLOPS of FP16 (2:1 ratio), while the RX 6650M XT produces 9.896 TFLOPS FP32 and 19.79 TFLOPS FP16. Pixel rates tell a different story: the RX 6650M XT achieves 154.6 GPixel/s versus 93.95 GPixel/s for the Pro Vega 64X, despite having the same 64 ROPs. Texture rates are closer: 375.8 GTexel/s for the Pro Vega 64X versus 309.2 GTexel/s for the RX 6650M XT.

API support differs in DirectX and Vulkan versions. The Pro Vega 64X supports DirectX 12 (12_1) and Vulkan 1.3, while the RX 6650M XT supports DirectX 12 Ultimate (12_2) and Vulkan 1.4. Both support OpenGL 4.6. The RX 6650M XT also has a predecessor listed (Polaris Mobile), while the Pro Vega 64X has none. Release dates are about three years apart: March 2019 for the Pro Vega 64X and January 2022 for the RX 6650M XT.

Where Each One Wins

The AMD Radeon Pro Vega 64X wins in raw compute performance and memory capacity. Its 16 GB of HBM2 provides double the memory of the RX 6650M XT’s 8 GB, and its 512.0 GB/s bandwidth is exactly twice the 256.0 GB/s of its rival. The 2% OpenCL lead and the additional Metal score make it the stronger choice for compute-heavy workloads like rendering, scientific simulation, or any task that stresses FP32 throughput. Its higher FP32 rating of 12.03 TFLOPS versus 9.896 TFLOPS further supports this position. The Pro Vega 64X also has a higher average score and a higher percentile ranking, making it the overall performance leader.

The AMD Radeon RX 6650M XT wins in efficiency and modern feature support. Its 120 W TDP is less than half the 250 W of the Pro Vega 64X, a crucial advantage for mobile implementations. The 7 nm process node makes it physically smaller and denser, which is beneficial for space-constrained designs. The inclusion of 32 ray tracing cores gives it capabilities the Pro Vega 64X lacks entirely, making it the better option for any workload that uses hardware-accelerated ray tracing. Its higher pixel rate (154.6 GPixel/s vs 93.95 GPixel/s) suggests better fill-rate performance in some scenarios, despite lower overall shading throughput. The RX 6650M XT also supports newer API versions, including DirectX 12 Ultimate and Vulkan 1.4, which may be relevant for future software compatibility.

In a direct application split: users with large datasets or memory-intensive compute tasks should pick the Pro Vega 64X. Users prioritizing power efficiency, ray tracing support, or newer API features should pick the RX 6650M XT, accepting a small performance loss in traditional compute benchmarks.