AMD Radeon Pro Duo vs NVIDIA Quadro M5000 Comparison

FAQ

Q: What is the overall benchmark score difference between the AMD Radeon Pro Duo and the NVIDIA Quadro M5000?

A: In the database, the AMD Radeon Pro Duo holds an average benchmark score of 35,860, while the NVIDIA Quadro M5000 averages 31,206. This places the Radeon Pro Duo approximately 14.9% higher in average score, based on the recorded data.

Q: How do these two GPUs rank against all other GPUs in the database?

A: The AMD Radeon Pro Duo sits at the 80th percentile among all GPUs, while the NVIDIA Quadro M5000 sits at the 76th percentile. Both are above the midpoint, but the Radeon Pro Duo ranks clearly higher in the overall distribution.

Q: Which GPU has more memory, and what type is it?

A: The NVIDIA Quadro M5000 has 8 GB of GDDR5 memory with a 256-bit bus and 211.6 GB/s bandwidth. The AMD Radeon Pro Duo has 4 GB of HBM memory with a 4096-bit bus and 512.0 GB/s bandwidth. The M5000 has double the capacity, while the Radeon Pro Duo has significantly higher bandwidth.

Q: What is the power consumption difference between the two cards?

A: The AMD Radeon Pro Duo has a TDP of 350 W and requires a 750 W suggested PSU with 3x 8-pin power connectors. The NVIDIA Quadro M5000 has a TDP of 150 W, a 450 W suggested PSU, and uses a single 6-pin connector. The M5000 consumes less than half the power of the Radeon Pro Duo.

Q: Which GPU has better API support for Vulkan?

A: The NVIDIA Quadro M5000 supports Vulkan 1.4, while the AMD Radeon Pro Duo supports Vulkan 1.2.170. DirectX support is similar, with the M5000 at 12_1 and the Radeon Pro Duo at 12_0.

Q: What is the only head-to-head benchmark recorded in the database?

A: The only direct head-to-head benchmark is Geekbench OpenCL. The AMD Radeon Pro Duo scored 35,860 against the M5000's 29,481, giving the Radeon Pro Duo a 21.6% advantage in that single test.

Architecture Differences

The AMD Radeon Pro Duo uses the Capsaicin chip built on GCN 3.0 architecture, manufactured on a 28 nm process at TSMC. It integrates 8,900 million transistors on a 596 mm² die, resulting in a transistor density of 14.9M per mm². The NVIDIA Quadro M5000 uses the GM204 chip based on Maxwell 2.0 architecture, also on TSMC's 28 nm process, but with 5,200 million transistors on a 398 mm² die, giving a density of 13.1M per mm². The Radeon Pro Duo has a substantially larger and denser chip.

The Radeon Pro Duo features 4,096 shading units, 256 texture mapping units, and 64 raster operation pipelines. The M5000 has 2,048 shading units, 128 TMUs, and 64 ROPs. The Radeon Pro Duo doubles the shading units and TMUs while matching the ROP count. The memory architecture differs fundamentally: the Radeon Pro Duo uses 4 GB of HBM on a 4096-bit bus with 512.0 GB/s bandwidth, whereas the M5000 uses 8 GB of GDDR5 on a 256-bit bus with 211.6 GB/s bandwidth. The memory clock reflects this, with the Radeon Pro Duo at 500 MHz (1000 Mbps effective) versus the M5000's 1653 MHz (6.6 Gbps effective).

Clock speeds also differ. The Radeon Pro Duo has no listed base or boost clock in the database, while the M5000 has a base clock of 861 MHz and a boost clock of 1038 MHz. The Radeon Pro Duo's pixel rate is 64.00 GPixel/s, slightly below the M5000's 66.43 GPixel/s, but its texture rate of 256.0 GTexel/s far exceeds the M5000's 132.9 GTexel/s. The Radeon Pro Duo delivers 8.192 TFLOPS of FP32 compute and 8.192 TFLOPS of FP16 (1:1), while the M5000 delivers 4.252 TFLOPS of FP32 and has no listed FP16 capability.

Display outputs differ as well. The Radeon Pro Duo has 1x HDMI 1.4a and 3x DisplayPort 1.2, while the M5000 has 1x DVI and 4x DisplayPort 1.2. Both use PCIe 3.0 x16 and are dual-slot cards. The Radeon Pro Duo is 277 mm long (10.9 inches) and 111 mm high (4.4 inches), while the M5000 is 267 mm long (10.5 inches) and 111 mm high (4.4 inches). Both cards are end-of-life products.

The Verdict

The data points to a clear performance leader in compute workloads. The AMD Radeon Pro Duo scores 35,860 in Geekbench OpenCL against the M5000's 29,481, a 21.6% advantage. Its FP32 throughput of 8.192 TFLOPS is nearly double the M5000's 4.252 TFLOPS, and its texture rate of 256.0 GTexel/s is roughly double the M5000's 132.9 GTexel/s. For workloads that stress raw compute, shading, and texture throughput, the Radeon Pro Duo is the stronger card.

However, the NVIDIA Quadro M5000 offers advantages in other areas. It has 8 GB of memory versus 4 GB, which matters for large datasets that exceed the Radeon Pro Duo's capacity. Its power draw of 150 W is less than half the Radeon Pro Duo's 350 W, and it requires only a 450 W PSU and a single 6-pin connector, making it far easier to integrate into existing systems. The M5000 also supports a newer Vulkan version (1.4 versus 1.2.170) and DirectX 12_1 versus 12_0.

The choice depends on the workload. For compute-heavy tasks where the model fits within 4 GB, the Radeon Pro Duo is the faster card by a significant margin. For memory-intensive tasks, lower power envelopes, or newer API requirements, the M5000 is the more practical option. The percentile ranking supports this: the Radeon Pro Duo at the 80th percentile outperforms the M5000 at the 76th percentile, but the M5000 remains a capable card within its own generation.

Specification Differences

The two cards differ across nearly every core specification. The Radeon Pro Duo has 4,096 shading units versus 2,048 on the M5000, and 256 TMUs versus 128. Both have 64 ROPs. The Radeon Pro Duo's transistor count is 8,900 million on a 596 mm² die, versus 5,200 million on 398 mm² for the M5000. The Radeon Pro Duo's transistor density is 14.9M per mm², ahead of the M5000's 13.1M per mm².

Memory capacity favors the M5000 at 8 GB versus 4 GB, but the Radeon Pro Duo has a 4096-bit bus versus 256-bit, and bandwidth of 512.0 GB/s versus 211.6 GB/s. The Radeon Pro Duo uses HBM memory at 500 MHz (1000 Mbps effective), while the M5000 uses GDDR5 at 1653 MHz (6.6 Gbps effective). The Radeon Pro Duo has no listed base or boost clocks, whereas the M5000 lists 861 MHz base and 1038 MHz boost.

Compute rates differ sharply. The Radeon Pro Duo delivers 8.192 TFLOPS FP32 and 8.192 TFLOPS FP16 (1:1), while the M5000 delivers 4.252 TFLOPS FP32 and no FP16 figure. Pixel rates are nearly identical at 64.00 GPixel/s and 66.43 GPixel/s respectively, but texture rates diverge at 256.0 GTexel/s versus 132.9 GTexel/s. The Radeon Pro Duo's TDP is 350 W with 3x 8-pin connectors and a 750 W suggested PSU, versus 150 W with 1x 6-pin and a 450 W suggested PSU for the M5000.

API support differs in DirectX and Vulkan versions. The Radeon Pro Duo supports DirectX 12 (12_0) and Vulkan 1.2.170, while the M5000 supports DirectX 12 (12_1) and Vulkan 1.4. Both support OpenGL 4.6. Display outputs are 1x HDMI 1.4a plus 3x DisplayPort 1.2 on the Radeon Pro Duo, versus 1x DVI plus 4x DisplayPort 1.2 on the M5000. Physical dimensions are close: 277 mm length for the Radeon Pro Duo versus 267 mm for the M5000, both at 111 mm height and dual-slot width.

Head-to-Head Benchmarks

The database records a single head-to-head benchmark between these two cards: Geekbench OpenCL. The AMD Radeon Pro Duo scored 35,860, while the NVIDIA Quadro M5000 scored 29,481. The Radeon Pro Duo won this test with a 21.6% delta. This is a substantial margin, indicating a clear performance gap in OpenCL compute workloads. The Radeon Pro Duo's nearest rivals in the database include the NVIDIA Quadro GV100 at 35,520 (1% behind), the GeForce RTX 5070 Ti Mobile at 35,435 (1.2% behind), the NVIDIA T1000 at 36,289 (1.2% ahead), and the AMD Radeon RX 5300M at 36,529 (1.8% ahead). The M5000's nearest rivals include the GRID M60-1Q at 31,220 (0% difference), the RTX 4070 Ti SUPER at 31,087 (0.4% behind), the RTX PRO 4500 Blackwell at 31,532 (1% ahead), and the TITAN RTX at 31,676 (1.5% ahead). This places the Radeon Pro Duo in a higher performance tier, surrounded by newer or more powerful cards, while the M5000 sits among mid-range and older GPUs.

The M5000 also has a recorded Geekbench Vulkan score of 32,931, though the Radeon Pro Duo has no comparable Vulkan benchmark in the database. This means the M5000's average benchmark score of 31,206 is pulled from both its OpenCL and Vulkan results, while the Radeon Pro Duo's average of 35,860 is based solely on its OpenCL score. Even with this dual-benchmark averaging, the M5000 remains well below the Radeon Pro Duo's single-test score.

Where Each One Wins

The AMD Radeon Pro Duo wins in raw compute performance. Its 21.6% OpenCL advantage over the M5000 is the headline result. Its FP32 throughput of 8.192 TFLOPS is nearly double the M5000's 4.252 TFLOPS, and its texture rate of 256.0 GTexel/s is nearly double the M5000's 132.9 GTexel/s. For workloads that rely heavily on shading, texture sampling, and parallel floating-point math, the Radeon Pro Duo is the clear winner. Its 4096-bit memory bus and 512.0 GB/s bandwidth also give it a decisive advantage in memory bandwidth-bound tasks, provided the working set fits within 4 GB. The 80th percentile ranking versus the M5000's 76th percentile reinforces this position.

The NVIDIA Quadro M5000 wins in memory capacity and power efficiency. Its 8 GB frame buffer doubles the Radeon Pro Duo's 4 GB, which is critical for rendering scenes or processing datasets that exceed 4 GB. Its 150 W TDP and 450 W suggested PSU make it far easier to deploy in workstations with limited power budgets, and a single 6-pin connector simplifies installation compared to the Radeon Pro Duo's 3x 8-pin requirement. The M5000 also supports Vulkan 1.4 and DirectX 12_1, newer API versions than the Radeon Pro Duo's Vulkan 1.2.170 and DirectX 12_0. In scenarios where API compatibility matters, the M5000 is the safer choice.

In summary, the Radeon Pro Duo wins for compute-heavy workloads with modest memory requirements, while the M5000 wins for memory-intensive tasks, power-constrained environments, and newer API requirements. The single head-to-head test favors the Radeon Pro Duo, but the M5000's other attributes make it the more balanced card for general workstation use.