AMD Radeon Pro Duo vs NVIDIA GeForce RTX 4080 Mobile Comparison

# NVIDIA GeForce RTX 4080 Mobile vs AMD Radeon Pro Duo

The data is unambiguous: the NVIDIA GeForce RTX 4080 Mobile wins the only shared benchmark by a 345% margin, scores higher in its average benchmark result despite being a mobile part, and offers modern architecture features the Radeon Pro Duo cannot match. The Radeon Pro Duo, an end-of-life dual-GPU workstation card from 2016, retains a narrow 1% average-score edge over the RTX 4080 Mobile in its nearest-rival comparison, but that is a product of different test pools, not real competitiveness. The verdict is simple: for any modern workload, the RTX 4080 Mobile is the only rational choice; the Radeon Pro Duo should only be considered by legacy software compatibility, and even then its 4 GB memory and 28 nm node make it a hard sell.

The Verdict

Benchmark results place the NVIDIA GeForce RTX 4080 Mobile in the 81st percentile of all GPUs, while the AMD Radeon Pro Duo sits at the 80th percentile — a negligible overall ranking difference that masks a massive per-test gap. In the sole head-to-head benchmark available, Geekbench OpenCL, the RTX 4080 Mobile scores 159,575 against the Radeon Pro Duo's 35,860, a 345% advantage. The average benchmark score tells a similar story: the RTX 4080 Mobile averages 38,135 across nine tests, while the Radeon Pro Duo averages 35,860 from a single OpenCL result. The Radeon Pro Duo's nearest rivals include the NVIDIA Quadro GV100 (1% lower) and the GeForce RTX 5070 Ti Mobile (1.2% lower), which shows it sits in a competitive tier — but only against much older or lower-tier parts. The RTX 4080 Mobile's nearest rivals are the GeForce MX570 (-0.4%), RTX 5080 Mobile (-0.6%), and RTX 4070 (1.3%), placing it in a completely different performance class. The verdict: the RTX 4080 Mobile is for anyone needing current-generation performance, ray tracing, DLSS-class features, or high-bandwidth memory in a portable package. The Radeon Pro Duo is a historical curiosity — its 350 W TDP, dual-slot design, and 3x 8-pin power requirement make it impractical for modern systems, and its 4 GB HBM memory is insufficient for contemporary workloads. No scenario in the data justifies choosing the Radeon Pro Duo for new purchases.

Architecture Differences

The RTX 4080 Mobile is built on NVIDIA's Ada Lovelace architecture using the AD104 chip, fabricated on TSMC's 5 nm process with 35,800 million transistors on a 294 mm² die, yielding a transistor density of 121.8 million per mm². The Radeon Pro Duo uses AMD's GCN 3.0 architecture with the "Capsaicin" chip, on TSMC's 28 nm process with just 8,900 million transistors spread across a 596 mm² die, resulting in a density of 14.9 million per mm² — a stark contrast showing nearly a decade of fabrication progress. The RTX 4080 Mobile features 7,424 shading units, 232 TMUs, 80 ROPs, 58 ray-tracing cores, and 232 tensor cores. The Radeon Pro Duo has 4,096 shading units, 256 TMUs, and 64 ROPs, but has no ray-tracing cores and no tensor cores — critical omissions for any modern rendering or AI workload. Memory configurations diverge sharply: the RTX 4080 Mobile uses 12 GB of GDDR6 on a 192-bit bus with 432.0 GB/s bandwidth and 18 Gbps effective speed, while the Radeon Pro Duo uses 4 GB of HBM on a 4096-bit bus with 512.0 GB/s bandwidth and 1000 Mbps effective speed. The Radeon Pro Duo's wider bus gives it higher raw bandwidth, but the capacity deficit is severe. API support also differs: the RTX 4080 Mobile supports DirectX 12 Ultimate (12_2), Vulkan 1.4, and OpenGL 4.6, while the Radeon Pro Duo only reaches DirectX 12 (12_0), Vulkan 1.2.170, and OpenGL 4.6. The RTX 4080 Mobile uses a PCIe 4.0 x16 interface; the Radeon Pro Duo is limited to PCIe 3.0 x16.

Where Each One Wins

The RTX 4080 Mobile wins the only directly comparable benchmark — Geekbench OpenCL — by 345%, which is sufficient to declare a clean sweep in head-to-head testing. Across its broader benchmark suite, the RTX 4080 Mobile shows strengths in every category: PassMark G3D score of 24,926, GPU compute score of 11,191, DirectX 11 score of 244, DirectX 9 score of 286, DirectX 10 score of 157, DirectX 12 score of 96, and G2D score of 929. The Radeon Pro Duo has no equivalent scores in the data, so its only evidence of capability is the single Geekbench OpenCL result. The RTX 4080 Mobile's 12 GB memory and 432.0 GB/s bandwidth make it suitable for large textures and modern game assets, while its ray-tracing and tensor cores enable hardware-accelerated ray tracing and AI features that the Radeon Pro Duo physically cannot perform. The Radeon Pro Duo's 512.0 GB/s bandwidth from its 4096-bit HBM bus is its only statistical advantage, but with 4 GB capacity, that bandwidth is effectively wasted on small working sets. The Radeon Pro Duo's 8.192 TFLOPS FP32 and FP16 performance is less than a third of the RTX 4080 Mobile's 24.72 TFLOPS in both formats. The RTX 4080 Mobile also has higher pixel rate (133.2 GPixel/s vs 64.00 GPixel/s) and texture rate (386.3 GTexel/s vs 256.0 GTexel/s). The Radeon Pro Duo's only potential win is in legacy software that specifically requires GCN-era drivers or dual-GPU configurations, but no benchmark in the data supports that conclusion.

FAQ

Q: Which GPU has higher raw compute performance?

A: The NVIDIA GeForce RTX 4080 Mobile delivers 24.72 TFLOPS FP32 and FP16, while the AMD Radeon Pro Duo delivers 8.192 TFLOPS in both — the RTX 4080 Mobile is approximately three times faster in raw compute.

Q: How do their memory configurations compare?

A: The RTX 4080 Mobile has 12 GB GDDR6 on a 192-bit bus with 432.0 GB/s bandwidth. The Radeon Pro Duo has 4 GB HBM on a 4096-bit bus with 512.0 GB/s bandwidth. The Radeon Pro Duo has higher bandwidth but far less capacity.

Q: Do both GPUs support ray tracing?

A: No. The RTX 4080 Mobile includes 58 ray-tracing cores and 232 tensor cores. The Radeon Pro Duo has no ray-tracing cores and no tensor cores, so it cannot accelerate ray tracing or AI workloads.

Q: Which GPU is more power-efficient?

A: The RTX 4080 Mobile has a TDP of 110 W and uses no external power connectors. The Radeon Pro Duo has a TDP of 350 W and requires 3x 8-pin power connectors and a 750 W suggested power supply. The RTX 4080 Mobile delivers far higher performance at less than one-third the power draw.

Q: What is the performance gap in the shared benchmark?

A: In Geekbench OpenCL, the RTX 4080 Mobile scores 159,575 versus the Radeon Pro Duo's 35,860, a 345% advantage for the NVIDIA part.

Q: Which GPU is more current?

A: The RTX 4080 Mobile was released in January 2023, is marked as Active production, and uses a 5 nm process. The Radeon Pro Duo was released in April 2016, is End-of-life, and uses a 28 nm process.

Head-to-Head Benchmarks

The data contains exactly one head-to-head benchmark: Geekbench OpenCL. The NVIDIA GeForce RTX 4080 Mobile scores 159,575, while the AMD Radeon Pro Duo scores 35,860. The delta is 345% in favor of the RTX 4080 Mobile — a performance gap so large that it renders the comparison almost meaningless for practical purposes. To contextualize this: the RTX 4080 Mobile's average benchmark score of 38,135 across nine tests is actually higher than the Radeon Pro Duo's single-test score of 35,860. That means the RTX 4080 Mobile's worst-performing individual tests (PassMark DirectX 12 at 96 and DirectX 10 at 157) are still within a factor of the Radeon Pro Duo's only recorded result, while its best scores (Geekbench OpenCL at 159,575 and Geekbench Vulkan at 145,807) are four to five times higher. The Radeon Pro Duo's nearest rivals in average score include the NVIDIA Quadro GV100 at 35,520 (1% lower) and the GeForce RTX 5070 Ti Mobile at 35,435 (1.2% lower), which suggests the Radeon Pro Duo performs at a level comparable to mid-range laptop GPUs from several generations later. Meanwhile, the RTX 4080 Mobile's nearest rivals — the GeForce MX570 at 38,299 (-0.4%), RTX 5080 Mobile at 38,349 (-0.6%), RTX 4070 at 37,648 (1.3%), and Tesla P4 at 37,628 (1.3%) — indicate it sits alongside desktop-class GPUs despite being a mobile component. The RTX 4080 Mobile wins the head-to-head count 1-0, and there is no benchmark in the data where the Radeon Pro Duo comes out ahead.

Specification Differences

The two GPUs differ in nearly every measurable specification. The RTX 4080 Mobile uses a 5 nm process with 35,800 million transistors on a 294 mm² die; the Radeon Pro Duo uses a 28 nm process with 8,900 million transistors on a 596 mm² die. Clock speeds: the RTX 4080 Mobile has a 1290 MHz base and 1665 MHz boost, with memory at 2250 MHz (18 Gbps effective); the Radeon Pro Duo has no base or boost clock listed, with memory at 500 MHz (1000 Mbps effective). Memory: 12 GB GDDR6 on 192-bit versus 4 GB HBM on 4096-bit. Bandwidth: 432.0 GB/s versus 512.0 GB/s. Compute units: 7,424 shading units, 232 TMUs, 80 ROPs, 58 RT cores, 232 tensor cores versus 4,096 shading units, 256 TMUs, 64 ROPs, no RT cores, no tensor cores. Pixel rate: 133.2 GPixel/s versus 64.00 GPixel/s. Texture rate: 386.3 GTexel/s versus 256.0 GTexel/s. FP32/FP16: 24.72 TFLOPS versus 8.192 TFLOPS. TDP: 110 W versus 350 W. Slot width: IGP versus dual-slot. Power connectors: none versus 3x 8-pin. Suggested PSU: not listed versus 750 W. Bus interface: PCIe 4.0 x16 versus PCIe 3.0 x16. Display outputs: portable device dependent versus 1x HDMI 1.4a and 3x DisplayPort 1.2. Dimensions: not listed for the RTX 4080 Mobile; the Radeon Pro Duo is 277 mm (10.9 inches) long and 111 mm (4.4 inches) tall. API support: DirectX 12 Ultimate (12_2), Vulkan 1.4, OpenGL 4.6 versus DirectX 12 (12_0), Vulkan 1.2.170, OpenGL 4.6. Production status: Active versus End-of-life. Release date: January 2023 versus April 2016. The Radeon Pro Duo has a launch MSRP of 1,499 USD; the RTX 4080 Mobile has no launch MSRP listed. The RTX 4080 Mobile's predecessor is GeForce 30 Mobile and successor is GeForce 50 Mobile; the Radeon Pro Duo's predecessor is FirePro GCN and successor is Radeon Pro Polaris.