AMD Radeon Pro 580 vs NVIDIA GeForce RTX 4080 SUPER Comparison

Where Each One Wins

The recorded data splits these two cards cleanly by era and intended workload. The NVIDIA GeForce RTX 4080 SUPER wins every head-to-head benchmark in the database, taking 2 of 2 direct comparisons. The AMD Radeon Pro 580, by contrast, does not win a single recorded test against the RTX 4080 SUPER.

The RTX 4080 SUPER dominates modern compute and graphics APIs. In Geekbench OpenCL, it scores 219,065 against the Radeon Pro 580's 38,457, a 469.6% advantage. In Geekbench Vulkan, the gap widens to 500.8%, with the NVIDIA card scoring 260,075 versus 43,285. These are not close contests; the RTX 4080 SUPER is in a different performance class entirely.

The Radeon Pro 580 does have one unique data point: a Geekbench Metal score of 39,213. The RTX 4080 SUPER has no recorded Metal benchmark, so in Apple-centric environments (the Radeon Pro 580 belongs to the Radeon Pro Mac 500 Series generation), the AMD card remains the only option with measured Metal performance. However, that score sits below the Radeon Pro 580's own OpenCL and Vulkan results, indicating it is not a strong performer even within its own test suite.

For users working in OpenCL or Vulkan, the RTX 4080 SUPER is categorically superior. The AMD card's only niche is Metal-specific workflows, where the database simply has no NVIDIA comparison. Beyond that, the data shows no workload where the Radeon Pro 580 closes the gap.

Architecture Differences

The architectural gap between these two is generational and massive. The RTX 4080 SUPER uses NVIDIA's Ada Lovelace architecture on the AD103 chip, built on a 5 nm TSMC process. The Radeon Pro 580 uses AMD's GCN 4.0 architecture on the Ellesmere chip, built on a 14 nm GlobalFoundries process. That is a three-generation jump in process technology, and it shows in every metric.

Transistor counts tell the story: the RTX 4080 SUPER packs 45,900 million transistors on a 379 mm² die, yielding a density of 121.1 million transistors per mm². The Radeon Pro 580 has just 5,700 million transistors on a 232 mm² die, at 24.6 million per mm². The NVIDIA chip is nearly five times denser, which directly enables its performance lead.

Clock speeds also diverge sharply. The RTX 4080 SUPER runs at a base of 2295 MHz and boosts to 2550 MHz, while the Radeon Pro 580 sits at 1100 MHz base and 1200 MHz boost. The NVIDIA card's memory clock is 1438 MHz (23 Gbps effective) versus the AMD's 1695 MHz (6.8 Gbps effective), though the memory type difference matters more: GDDR6X versus GDDR5.

The compute resources are not remotely comparable. The RTX 4080 SUPER has 10,240 shading units, 320 TMUs, and 112 ROPs. The Radeon Pro 580 has 2,304 shading units, 144 TMUs, and 32 ROPs. The NVIDIA card also brings 80 RT cores and 320 tensor cores; the AMD card has neither, as GCN 4.0 predates both hardware ray tracing and dedicated tensor hardware.

Memory capacity and bandwidth follow suit. The RTX 4080 SUPER offers 16 GB of GDDR6X on a 256-bit bus, delivering 736.3 GB/s. The Radeon Pro 580 has 8 GB of GDDR5 on the same 256-bit bus, but only 217.0 GB/s. The pixel rate is 285.6 GPixel/s versus 38.40 GPixel/s, and the texture rate is 816.0 GTexel/s versus 172.8 GTexel/s. FP32 compute is 52.22 TFLOPS versus 5.530 TFLOPS, a nearly tenfold difference.

Power and physical design differ as well. The RTX 4080 SUPER has a TDP of 320 W, requires a 16-pin connector, a 700 W suggested PSU, and is a triple-slot card measuring 310 mm long. The Radeon Pro 580 is an IGP (integrated graphics processor) with no power connectors, a 185 W TDP, and no listed dimensions. The NVIDIA card uses PCIe 4.0 x16; the AMD card uses PCIe 3.0 x16. API support also differs: the RTX 4080 SUPER supports DirectX 12 Ultimate (12_2) and Vulkan 1.4, while the Radeon Pro 580 only reaches DirectX 12 (12_0) and Vulkan 1.3.

Head-to-Head Benchmarks

The database records only two direct head-to-head benchmarks between these cards, and both are decisive NVIDIA wins.

In Geekbench OpenCL, the RTX 4080 SUPER scores 219,065 against the Radeon Pro 580's 38,457. That is a 469.6% delta, meaning the NVIDIA card delivers roughly 5.7 times the OpenCL performance. This test exercises general-purpose compute across the GPU's shader array, and the RTX 4080 SUPER's 10,240 shading units versus 2,304, combined with its 5 nm process and 52.22 TFLOPS FP32 throughput, explains the gap.

In Geekbench Vulkan, the RTX 4080 SUPER scores 260,075 against 43,285, a 500.8% delta. The NVIDIA card is over six times faster in this graphics API test. Vulkan leverages the RTX 4080 SUPER's newer architecture and higher fill rates, and the result aligns with the pixel rate and texture rate differences: 285.6 GPixel/s versus 38.40 GPixel/s, and 816.0 GTexel/s versus 172.8 GTexel/s.

The Radeon Pro 580's only additional benchmark is Geekbench Metal at 39,213, which has no NVIDIA counterpart in the database. That score is lower than its own OpenCL and Vulkan results, suggesting Metal is not a strength for this card. The RTX 4080 SUPER also holds a higher average benchmark score overall: 54,209 versus 40,318, a gap of roughly 34%.

The percentile ranks are close, though: the RTX 4080 SUPER sits at the 86th percentile among all GPUs, while the Radeon Pro 580 sits at the 82nd. This is surprising given the performance disparity, but it reflects the database's broader population, which includes many lower-end integrated and mobile parts. The RTX 4080 SUPER's nearest rivals include the RTX 4080 (0.1% lower average score) and Radeon Pro W5700X (1.1% lower), while the Radeon Pro 580's nearest rivals include the RTX 5070 (0.1% lower) and Radeon Pro WX 7100 (0.6% higher).

FAQ

Q: Which card has higher raw compute performance?

A: The RTX 4080 SUPER delivers 52.22 TFLOPS FP32 versus the Radeon Pro 580's 5.530 TFLOPS, a roughly 9.4x difference. Its shading unit count is 10,240 versus 2,304.

Q: Does the Radeon Pro 580 support hardware ray tracing?

A: No. The Radeon Pro 580 has no RT cores listed, while the RTX 4080 SUPER includes 80 RT cores and 320 tensor cores.

Q: Which card has more memory bandwidth?

A: The RTX 4080 SUPER has 736.3 GB/s from 16 GB of GDDR6X on a 256-bit bus. The Radeon Pro 580 has 217.0 GB/s from 8 GB of GDDR5 on the same bus width.

Q: Can the Radeon Pro 580 run modern DirectX titles?

A: It supports DirectX 12 (12_0), but the RTX 4080 SUPER supports DirectX 12 Ultimate (12_2), which includes additional features. The NVIDIA card also supports Vulkan 1.4 versus 1.3 on the AMD card.

Q: How do their power requirements differ?

A: The RTX 4080 SUPER has a 320 W TDP, requires a 16-pin power connector, and suggests a 700 W PSU. The Radeon Pro 580 has a 185 W TDP with no power connectors, as it is an IGP.

Q: Which card is better for OpenCL compute workloads?

A: The RTX 4080 SUPER scores 219,065 in Geekbench OpenCL versus 38,457 for the Radeon Pro 580, a 469.6% advantage. The NVIDIA card is categorically faster in this test.

The Verdict

The data is unambiguous: the NVIDIA GeForce RTX 4080 SUPER outperforms the AMD Radeon Pro 580 in every measurable compute and graphics test where both have results. The OpenCL and Vulkan deltas of 469.6% and 500.8% are not incremental improvements; they represent a multi-generational leap in architecture, process node, and memory technology.

The RTX 4080 SUPER is the clear choice for any workload involving OpenCL, Vulkan, or modern DirectX 12 Ultimate features. Its 16 GB of GDDR6X memory, 736.3 GB/s bandwidth, and 80 RT cores make it suitable for current-generation gaming, ray-traced rendering, and compute-heavy tasks. Its 86th percentile rank among all GPUs and average benchmark score of 54,209 place it near the top of the database.

The Radeon Pro 580, with its 82nd percentile and 40,318 average score, serves a narrow purpose. Its only unique data point is Geekbench Metal at 39,213, which the RTX 4080 SUPER cannot be compared against. For users locked into Metal-based workflows on Apple platforms, the Radeon Pro 580 remains a functional option, but its performance is modest even within that API. It has no ray tracing, no tensor cores, and its 14 nm process places it far behind modern silicon.

The verdict splits by platform: if the workload is Metal-centric and Apple-bound, the Radeon Pro 580 is the only card in this comparison with recorded data. If the workload is anything else, the RTX 4080 SUPER wins by margins that are difficult to overstate. The database shows no scenario where the AMD card closes the gap, and its end-of-life status on both cards confirms that this is a legacy versus current-generation matchup.