AMD Radeon Pro 5300 vs NVIDIA RTX 5880 Ada Generation Comparison

The NVIDIA RTX 5880 Ada Generation and AMD Radeon Pro 5300 occupy vastly different tiers of the workstation GPU market, and the benchmark data reflects a complete mismatch in compute capability. The RTX 5880 Ada is a flagship-class accelerator with 48 GB of memory and a 285 W power envelope, while the Radeon Pro 5300 is an entry-level, end-of-life mobile part with 4 GB and an 85 W TDP. The single shared benchmark — Geekbench OpenCL — shows the NVIDIA card delivering a score of 326,898 against the AMD’s 38,747, a 743.7% advantage. This is not a contest of equals; it is a comparison of two products separated by roughly four years of architectural evolution and a 12x difference in transistor count.

Head-to-Head Benchmarks

The only direct benchmark overlap between the two cards is Geekbench OpenCL, and the result is emphatic. The NVIDIA RTX 5880 Ada Generation scores 326,898, while the AMD Radeon Pro 5300 manages 38,747. That translates to a delta of 743.7% in favor of the NVIDIA part. In practical terms, the RTX 5880 completes the same OpenCL workload roughly eight and a half times faster than the Radeon Pro 5300 — a gap so large that it cannot be bridged by driver optimizations or workload tuning.

Contextualizing the Radeon Pro 5300’s score against its own nearest rivals puts that 38,747 figure in perspective. Its average benchmark score across all tests is 40,870, placing it in the 82nd percentile of all GPUs. Its nearest rivals include the NVIDIA GeForce RTX 3080 Ti (average score 41,187, delta -0.8%), the GeForce RTX 5070 (40,377, delta 1.2%), and the AMD Radeon Pro 580 (40,318, delta 1.4%). This means the Radeon Pro 5300 is essentially performance-par with desktop gaming cards from the high-end segment, but it lacks the memory capacity and bandwidth of those parts for large datasets.

The RTX 5880 Ada, by contrast, has an average benchmark score of 45,972 across its test suite, placing it in the 85th percentile. Its nearest rivals are the NVIDIA RTX A2000 (average score 46,043, delta -0.2%), the Intel Arc A730M (45,592, delta 0.8%), and the AMD Radeon Pro 5500 XT (45,384, delta 1.3%). The RTX 5880’s OpenCL score of 326,898 is dramatically higher than its own average score, indicating that its compute-heavy architecture — 14,080 shading units and 110 RT cores — excels in raw compute throughput scenarios more than in the synthetic DirectX tests where it scores far lower (e.g., Passmark DirectX 12 at 70).

The Radeon Pro 5300’s other scores — Geekbench Metal at 48,070 and Geekbench Vulkan at 35,793 — show that it is a competent API-specific performer, but those tests have no NVIDIA counterpart in the data, so no direct comparison is possible. What is clear is that the NVIDIA card’s OpenCL dominance is not an outlier; it aligns with its superior hardware specifications across every measurable category.

FAQ

Q: Which card has the higher OpenCL benchmark score?

A: The NVIDIA RTX 5880 Ada Generation scores 326,898 in Geekbench OpenCL, which is 743.7% higher than the AMD Radeon Pro 5300’s 38,747.

Q: What is the Radeon Pro 5300’s best benchmark result?

A: The Radeon Pro 5300’s highest recorded score is 48,070 in Geekbench Metal, followed by 38,747 in OpenCL and 35,793 in Vulkan.

Q: How does the RTX 5880 Ada compare to its nearest rival, the RTX A2000?

A: The RTX 5880 Ada has an average benchmark score of 45,972, which is 0.2% lower than the RTX A2000’s 46,043. The two are effectively performance-equivalent in aggregate metrics.

Q: Does the Radeon Pro 5300 have any benchmark where it beats a high-end desktop GPU?

A: Its average score of 40,870 is 1.4% higher than the AMD Radeon Pro 580 (40,318) and 2% higher than the AMD Radeon Pro WX 7100 (40,063), showing it outperforms older workstation cards.

Q: Which card has a higher percentile ranking among all GPUs?

A: The RTX 5880 Ada sits in the 85th percentile, while the Radeon Pro 5300 is in the 82nd percentile — a modest gap despite the massive OpenCL delta.

Q: What memory configurations do the two cards offer?

A: The RTX 5880 Ada has 48 GB of GDDR6 on a 384-bit bus with 864.0 GB/s bandwidth, while the Radeon Pro 5300 has 4 GB of GDDR6 on a 128-bit bus with 224.0 GB/s bandwidth.

Architecture Differences

The two GPUs are built on fundamentally different architectures and process nodes. The NVIDIA RTX 5880 Ada uses the AD102 chip with Ada Lovelace architecture, fabricated on a 5 nm process at TSMC with 76,300 million transistors on a 609 mm² die. The AMD Radeon Pro 5300 uses the Navi 14 chip with RDNA 1.0 architecture, fabricated on a 7 nm process at the same foundry with 6,400 million transistors on a 158 mm² die. The transistor density difference is stark: 125.3 million per mm² for NVIDIA versus 40.5 million per mm² for AMD.

The RTX 5880 Ada features 14,080 shading units, 440 texture mapping units, 176 raster operation units, 110 RT cores, and 440 tensor cores. It supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4. The Radeon Pro 5300 has 1,280 shading units, 80 TMUs, and 32 ROPs, with no dedicated RT or tensor cores. It supports DirectX 12 (12_1), OpenGL 4.6, and Vulkan 1.4 — the lower DirectX feature level reflects its older architecture.

Clock speeds and compute rates further separate the two. The RTX 5880 Ada runs at a 975 MHz base and 2460 MHz boost, delivering 69.27 TFLOPS of FP32 and FP16 (at 1:1 ratio). The Radeon Pro 5300 runs at 1000 MHz base and 1650 MHz boost, delivering 4.224 TFLOPS of FP32 and 8.448 TFLOPS of FP16 (at 2:1 ratio). The NVIDIA card’s FP32 throughput is over 16 times higher, and its FP16 performance is 8 times higher despite the AMD card’s 2:1 FP16 advantage.

The memory subsystem also reflects the generational gap. The RTX 5880 Ada’s 48 GB GDDR6 on a 384-bit bus provides 864.0 GB/s bandwidth versus the Radeon Pro 5300’s 4 GB GDDR6 on a 128-bit bus at 224.0 GB/s. The NVIDIA card has a memory clock of 2250 MHz (18 Gbps effective), while the AMD card runs at 1750 MHz (14 Gbps effective). Pixel and texture rates are equally lopsided: 433.0 GPixel/s and 1,082.4 GTexel/s for NVIDIA versus 52.80 GPixel/s and 132.0 GTexel/s for AMD.

The Verdict

The data is unambiguous: the NVIDIA RTX 5880 Ada Generation is the superior product for any workload that demands raw compute, memory capacity, or bandwidth. Its 743.7% lead in OpenCL, 48 GB versus 4 GB memory, and 864.0 GB/s versus 224.0 GB/s bandwidth make it the only choice for large-scale rendering, simulation, or AI inference. The Radeon Pro 5300, with its end-of-life status and IGP slot width, is suited only for low-power, light-duty tasks where its 85 W TDP and lack of external power connectors are acceptable trade-offs.

However, the Radeon Pro 5300 is not without merit in its niche. Its average benchmark score of 40,870 places it above the AMD Radeon Pro 580 and WX 7100, and it matches the performance of desktop GeForce RTX 3080 Ti and RTX 5070 cards. For users constrained by a 250 W system power supply or those needing a card with no display outputs for headless compute, the Radeon Pro 5300 offers a functional baseline. But the RTX 5880 Ada’s 85th percentile ranking and active production status mean it will continue to receive driver support and remain viable for years, whereas the Radeon Pro 5300 is end-of-life.

Benchmark results indicate that the RTX 5880 Ada is not merely faster — it is in a different performance class altogether. The only scenario where the Radeon Pro 5300 makes sense is when its lower power draw (85 W versus 285 W) and IGP form factor are mandatory, and even then, users must accept a 4 GB memory ceiling that severely limits workload sizes.

Specification Differences

| Specification | NVIDIA RTX 5880 Ada Generation | AMD Radeon Pro 5300 |

|---|---|---|

| Architecture | Ada Lovelace | RDNA 1.0 |

| Process Node | 5 nm | 7 nm |

| Transistors | 76,300 million | 6,400 million |

| Die Size | 609 mm² | 158 mm² |

| Base Clock | 975 MHz | 1000 MHz |

| Boost Clock | 2460 MHz | 1650 MHz |

| Memory Size | 48 GB | 4 GB |

| Memory Bus | 384 bit | 128 bit |

| Memory Bandwidth | 864.0 GB/s | 224.0 GB/s |

| Shading Units | 14,080 | 1,280 |

| TMUs | 440 | 80 |

| ROPs | 176 | 32 |

| RT Cores | 110 | None |

| Tensor Cores | 440 | None |

| FP32 Performance | 69.27 TFLOPS | 4.224 TFLOPS |

| FP16 Performance | 69.27 TFLOPS (1:1) | 8.448 TFLOPS (2:1) |

| TDP | 285 W | 85 W |

| Slot Width | Dual-slot | IGP |

| Power Connectors | 1x 16-pin | None |

| Suggested PSU | 600 W | 250 W |

| Bus Interface | PCIe 4.0 x16 | PCIe 4.0 x8 |

| Display Outputs | 4x DisplayPort 1.4a | No outputs |

| DirectX Support | 12 Ultimate (12_2) | 12 (12_1) |

| Production Status | Active | End-of-life |

| Release Date | 2024-01-04 | 2020-08-03 |

Where Each One Wins

The RTX 5880 Ada Generation wins in every performance-critical scenario. Its 14,080 shading units and 440 tensor cores make it ideal for GPU-accelerated compute, machine learning inference, and real-time ray tracing. The 48 GB memory pool is sufficient for massive 3D scenes, large language models, or multi-display 4K output, and the 864.0 GB/s bandwidth ensures data-intensive workloads are not memory-bound. With a dual-slot form factor and 1x 16-pin power connector, it fits into standard workstation chassis and delivers 69.27 TFLOPS of FP32 performance.

The Radeon Pro 5300 wins only in power efficiency and physical constraints. Its 85 W TDP requires no external power connectors and can run on a 250 W system PSU, making it suitable for compact or legacy systems. The IGP slot width means it can be installed in space-constrained environments where a dual-slot card would not fit. Its 4 GB memory and 224.0 GB/s bandwidth are adequate for basic 2D rendering or light compute tasks, and its 8.448 TFLOPS of FP16 performance (at 2:1 ratio) offers some flexibility for mixed-precision work.

In terms of ecosystem, the RTX 5880 Ada’s Active production status and 2024 release date mean it is a current product with ongoing support, while the Radeon Pro 5300’s end-of-life status and 2020 release date indicate it is no longer developed. The NVIDIA card’s support for DirectX 12 Ultimate and Vulkan 1.4 aligns with modern software stacks, whereas the AMD card’s DirectX 12 (12_1) is one feature level behind. For any user choosing between these two, the data overwhelmingly favors the RTX 5880 Ada Generation — unless the hard constraints of power, space, or cost-force consideration of the Radeon Pro 5300.