AMD Radeon Pro 5300 vs NVIDIA GeForce RTX 5090 Mobile Comparison

The NVIDIA GeForce RTX 5090 Mobile and AMD Radeon Pro 5300 represent two entirely different eras of mobile graphics, and the benchmark data reflects a generational chasm rather than a close contest. The RTX 5090 Mobile is a current-generation flagship built on Blackwell 2.0, while the Radeon Pro 5300 is an end-of-life workstation part from the RDNA 1.0 era. While both are integrated into portable devices, their architectural foundations, memory configurations, and raw compute capabilities place them in different performance stratospheres. This analysis examines the data to show exactly where each card stands, what the numbers mean for real-world workloads, and which user should consider which option.

FAQ

Q: How much faster is the NVIDIA GeForce RTX 5090 Mobile than the AMD Radeon Pro 5300 in OpenCL?

A: The RTX 5090 Mobile scores 201,834 in Geekbench OpenCL, which is 420.9% higher than the Radeon Pro 5300’s 38,747. This is a massive lead, indicating the NVIDIA part is roughly five times faster in this compute workload.

Q: Which card has more VRAM, and why does that matter?

A: The RTX 5090 Mobile has 24 GB of GDDR7 memory on a 256-bit bus, while the Radeon Pro 5300 has 4 GB of GDDR6 on a 128-bit bus. The NVIDIA card’s memory bandwidth of 896.0 GB/s is four times the AMD card’s 224.0 GB/s, which is critical for large datasets and high-resolution textures.

Q: Do both cards support modern graphics APIs like Vulkan and DirectX 12?

A: Yes, both support Vulkan 1.4 and DirectX 12. The RTX 5090 Mobile supports DirectX 12 Ultimate (12_2), while the Radeon Pro 5300 is limited to DirectX 12 (12_1). The NVIDIA card also adds hardware ray tracing cores, which the AMD card lacks entirely.

Q: What is the performance percentile ranking for each card?

A: The RTX 5090 Mobile sits in the 84th percentile of all GPUs, while the Radeon Pro 5300 is in the 82nd percentile. Despite the huge benchmark gap, both rank similarly because the percentile includes a wide range of integrated and entry-level parts.

Q: Which card has a higher boost clock speed?

A: The AMD Radeon Pro 5300 has a boost clock of 1650 MHz, while the RTX 5090 Mobile boosts to 1515 MHz. However, the NVIDIA card’s much higher shader count and newer architecture make clock speed comparisons irrelevant to overall performance.

Q: Is the AMD card still in production?

A: No, the Radeon Pro 5300 is listed as "End-of-life" with a release date of August 2020. The RTX 5090 Mobile is "Active" and was released in March 2025.

Architecture Differences

The architectural gap between these two GPUs is stark and explains nearly every performance difference. The RTX 5090 Mobile uses the GB203 chip built on TSMC’s 5 nm process, packing 45,600 million transistors into a 378 mm² die. The Radeon Pro 5300 uses the Navi 14 chip on TSMC’s 7 nm process, with just 6,400 million transistors on a 158 mm² die. That means the NVIDIA chip has roughly seven times the transistor count and a transistor density of 120.6 million per mm² versus 40.5 million per mm² for AMD.

The compute resources diverge dramatically. The RTX 5090 Mobile has 10,496 shading units, 328 texture mapping units, and 112 ROPs, while the Radeon Pro 5300 has only 1,280 shading units, 80 TMUs, and 32 ROPs. The NVIDIA card also includes 82 dedicated ray tracing cores and 328 tensor cores, which are entirely absent from the AMD chip. The RDNA 1.0 architecture in the Radeon Pro 5300 has no hardware ray tracing support at all.

Memory architecture reinforces the gap. The RTX 5090 Mobile uses 24 GB of GDDR7 across a 256-bit bus, yielding 896.0 GB/s of bandwidth. The Radeon Pro 5300 uses 4 GB of GDDR6 on a 128-bit bus, providing 224.0 GB/s. The NVIDIA card’s FP32 compute is 31.80 TFLOPS, while the AMD card delivers just 4.224 TFLOPS. Interestingly, the Radeon Pro 5300’s FP16 rate is 8.448 TFLOPS at a 2:1 ratio, whereas the RTX 5090 Mobile achieves 31.80 TFLOPS at a 1:1 ratio, meaning NVIDIA can maintain full throughput on half-precision workloads.

Head-to-Head Benchmarks

The only two shared benchmark results are Geekbench OpenCL and Vulkan, and both show overwhelming NVIDIA victories. In OpenCL, the RTX 5090 Mobile scores 201,834 against the Radeon Pro 5300’s 38,747, a delta of 420.9% in NVIDIA’s favor. This is not a marginal win; it is a five-fold performance difference that reflects the combination of more shaders, faster memory, and newer architecture.

The Vulkan result is even more lopsided. The RTX 5090 Mobile posts 198,405, while the Radeon Pro 5300 manages 35,793. The delta here is 454.3% for NVIDIA. Vulkan is a low-level API that scales well with raw hardware resources, so the NVIDIA card’s 10,496 shading units and 896 GB/s bandwidth simply overwhelm the AMD part’s 1,280 shading units and 224 GB/s bandwidth.

It is worth remembering the Radeon Pro 5300 has a Geekbench Metal score of 48,070, but the RTX 5090 Mobile does not have a comparable Metal benchmark in the data, so a direct comparison is impossible. Similarly, the RTX 5090 Mobile has extensive Passmark and 3DMark results—such as 30,034 in Passmark G3D and 5,871 in 3DMark Steel Nomad—but the Radeon Pro 5300 lacks results in those tests. The data only supports direct comparison on OpenCL and Vulkan, and both are decisive NVIDIA wins.

Specification Differences

The specification sheet tells a story of two completely different product classes. The RTX 5090 Mobile has a base clock of 990 MHz and a boost of 1515 MHz, while the Radeon Pro 5300 runs at 1000 MHz base and 1650 MHz boost. Despite the AMD card’s higher clocks, the NVIDIA card’s shading unit count is 8.2 times higher, making raw clock speeds irrelevant.

Memory is a major differentiator. The RTX 5090 Mobile offers 24 GB of GDDR7 with 896.0 GB/s bandwidth, while the Radeon Pro 5300 offers 4 GB of GDDR6 with 224.0 GB/s. The bus width is 256-bit versus 128-bit. The NVIDIA card’s pixel rate is 169.7 GPixel/s versus 52.80 GPixel/s for AMD, and its texture rate is 496.9 GTexel/s versus 132.0 GTexel/s.

Power and interface also differ. The RTX 5090 Mobile has a TDP of 95 W, while the Radeon Pro 5300 is rated at 85 W. The NVIDIA card uses PCIe 5.0 x16, while the AMD card uses PCIe 4.0 x8. Both are IGP slot width with no power connectors, but the AMD card lists a suggested PSU of 250 W, a figure absent for the NVIDIA part. The display outputs also differ: the RTX 5090 Mobile is "Portable Device Dependent," while the Radeon Pro 5300 has "No outputs," indicating it is designed for compute or rendering tasks without direct display connectivity. Finally, the RTX 5090 Mobile is in the 5 nm process node, while the Radeon Pro 5300 uses 7 nm.

Where Each One Wins

The RTX 5090 Mobile wins in every measurable category in the shared benchmark data. It is the clear choice for any workload that demands raw compute, ray tracing, or high-bandwidth memory. The 24 GB VRAM capacity and 896 GB/s bandwidth make it suitable for large-scale 3D rendering, machine learning inference, or any task where datasets exceed 4 GB. Its DirectX 12 Ultimate support and Vulkan 1.4 compatibility ensure it can handle the latest gaming and professional APIs. The presence of 82 RT cores and 328 tensor cores also makes it viable for real-time ray tracing and AI-accelerated features, which the AMD card cannot touch.

The Radeon Pro 5300, despite its lower performance, has a few contextual advantages based on the data. Its 85 W TDP is slightly lower than the RTX 5090 Mobile’s 95 W, which could matter in thermally constrained chassis. Its higher boost clock of 1650 MHz suggests it may respond well to workloads that are clock-bound rather than shader-bound. It also has a Geekbench Metal score of 48,070, which is a datapoint the NVIDIA card lacks entirely, indicating that the AMD card is at least a known quantity in Apple-centric Metal environments. However, its 4 GB VRAM and lack of ray tracing hardware make it a poor fit for modern AAA gaming or professional 3D workloads.

The Verdict

The data is unambiguous: the NVIDIA GeForce RTX 5090 Mobile is the superior GPU by an enormous margin. Its 420.9% OpenCL and 454.3% Vulkan leads over the Radeon Pro 5300 are not incremental improvements; they represent a generational leap in compute capability. The RTX 5090 Mobile’s 24 GB of GDDR7 memory, 10,496 shading units, and 31.80 TFLOPS of FP32 performance place it in the 84th percentile of all GPUs, and its nearest rivals—such as the AMD Radeon Pro 5500 XT at -0.5% delta and the NVIDIA GeForce RTX 4070 Ti at +0.8% delta—show it competes with desktop-class hardware.

For a builder or buyer choosing between these two, the decision is straightforward. The RTX 5090 Mobile is the only sensible pick for anyone needing high-end performance, modern API support, or ray tracing. The Radeon Pro 5300, at the 82nd percentile with an average benchmark score of 40,870 versus the RTX 5090 Mobile’s 45,152, is a legacy part that should only be considered if the workload is strictly Metal-based or if power draw is an absolute priority. Even then, the 10 W TDP difference is negligible compared to the five-fold performance gap. If the budget allows for the RTX 5090 Mobile, the Radeon Pro 5300 is not a viable alternative—it is a different class of hardware entirely.