AMD Instinct MI350X vs AMD Radeon PRO W7800 Comparison

# Head-to-Head Benchmarks

The data in the database presents a stark contrast between these two AMD professional accelerators. The AMD Instinct MI350X and the AMD Radeon PRO W7800 serve fundamentally different purposes, and their performance profiles reflect that division clearly.

The Radeon PRO W7800 is the only one of the two with recorded benchmark scores. In Geekbench OpenCL, it scores 154366 points, while in Geekbench Vulkan it reaches 175422 points. These results place the W7800 at the 97th percentile among all GPUs in the database, with an average benchmark score of 164894. The Instinct MI350X has no recorded benchmark scores and sits at the 50th percentile, with an average benchmark score of zero.

The Radeon PRO W7800's nearest rivals in the database show how competitive it is. The NVIDIA RTX A5500 scores 165217, which is only 0.2 percent ahead of the W7800's average. The NVIDIA RTX 4500 Ada Generation sits at 166094, a 0.7 percent lead. The AMD Radeon Pro W6900X reaches 168574, putting it 2.2 percent ahead. The only rival that the W7800 beats directly is the NVIDIA A100 PCIe 40 GB, which scores 162504, a 1.5 percent deficit relative to the W7800.

The raw compute specifications tell a different story. The MI350X delivers 72.09 TFLOPS of FP32 performance and the same 72.09 TFLOPS in FP16 with a 1:1 ratio. The W7800 delivers 45.25 TFLOPS FP32 and 90.50 TFLOPS FP16 with a 2:1 ratio. The MI350X leads in FP32 by a substantial margin, but the W7800 more than doubles its FP32 output when operating in FP16 mode, exceeding the MI350X's FP16 figure.

The MI350X also holds advantages in texture throughput, with 2,252.8 GTexel/s compared to the W7800's 707.0 GTexel/s. The W7800 counters with a pixel rate of 323.2 GPixel/s, while the MI350X shows 0 MPixel/s because it has no display outputs or raster operation units.

# The Verdict

The data indicates that the AMD Instinct MI350X is built for compute density and memory scale, while the AMD Radeon PRO W7800 is a conventional workstation GPU with display output support and measured application performance.

The MI350X uses the CDNA 4.0 architecture, which is designed around the MI350 256CU chip on a 3 nm process node from TSMC. It packs 185,000 million transistors onto a 2380 mm² die, giving a transistor density of 77.7 million per square millimeter. It uses HBM3e memory totaling 288 GB across an 8192-bit bus, yielding 8.19 TB/s of bandwidth. These figures point to a device aimed at large-scale compute workloads where memory capacity and bandwidth are the primary constraints.

The Radeon PRO W7800 uses RDNA 3.0 architecture with the Navi 31 chip, codenamed Plum Bonito. It is built on a 5 nm TSMC process and contains 57,700 million transistors on a 529 mm² die, with a higher transistor density of 109.1 million per square millimeter. It has 32 GB of GDDR6 memory on a 256-bit bus, delivering 576.0 GB/s. It is a dual-slot card with 3x DisplayPort 2.1 and 1x mini-DisplayPort 2.1 outputs, making it suitable for direct display connection.

The MI350X consumes up to 1000 W with a suggested PSU of 1400 W, while the W7800 has a 260 W TDP and a 600 W suggested PSU. The MI350X uses an OAM module form factor with no power connectors, meaning it relies on the host system for power delivery. The W7800 is a dual-slot card using two 8-pin power connectors.

The launch MSRP for the W7800 is 2,499 USD. The MI350X has no launch MSRP listed in the database.

# Where Each One Wins

The AMD Instinct MI350X wins in raw FP32 compute, delivering 72.09 TFLOPS against the W7800's 45.25 TFLOPS. It also leads in memory capacity with 288 GB versus 32 GB, memory bandwidth with 8.19 TB/s versus 576.0 GB/s, and memory bus width with 8192 bits versus 256 bits. Its texture rate of 2,252.8 GTexel/s is more than triple the W7800's 707.0 GTexel/s.

The AMD Radeon PRO W7800 wins in FP16 throughput with 90.50 TFLOPS versus the MI350X's 72.09 TFLOPS. It has a functional pixel pipeline at 323.2 GPixel/s, whereas the MI350X has none. The W7800 also supports display outputs, which the MI350X completely lacks. The W7800 has 70 ray tracing cores, while the MI350X lists none. The W7800 supports DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4, while the MI350X lists N/A for all three APIs.

The W7800 is the only one with measured benchmark results, achieving a 97th percentile rank among all GPUs in the database. The MI350X has no such measurements recorded.

# FAQ

Q: Which card has more FP32 compute power?

A: The AMD Instinct MI350X delivers 72.09 TFLOPS FP32, while the AMD Radeon PRO W7800 delivers 45.25 TFLOPS FP32.

Q: What is the benchmark performance of the Radeon PRO W7800?

A: The W7800 scores 154366 in Geekbench OpenCL and 175422 in Geekbench Vulkan, with an average benchmark score of 164894. It sits at the 97th percentile among all GPUs.

Q: How much memory does each card have?

A: The MI350X has 288 GB of HBM3e memory with 8.19 TB/s bandwidth. The W7800 has 32 GB of GDDR6 memory with 576.0 GB/s bandwidth.

Q: Can either card output video to a display?

A: Only the W7800 can. It has 3x DisplayPort 2.1 and 1x mini-DisplayPort 2.1 outputs. The MI350X has no display outputs.

Q: How does the W7800 compare to its nearest rivals?

A: The W7800 trails the NVIDIA RTX A5500 by 0.2 percent, the NVIDIA RTX 4500 Ada Generation by 0.7 percent, and the AMD Radeon Pro W6900X by 2.2 percent. It leads the NVIDIA A100 PCIe 40 GB by 1.5 percent.

Q: What are the power requirements for each card?

A: The MI350X has a 1000 W TDP with a suggested PSU of 1400 W. The W7800 has a 260 W TDP with a suggested PSU of 600 W.

# Architecture Differences

The two cards come from different architectural lineages within AMD. The MI350X uses CDNA 4.0, which is a compute-optimized architecture. The W7800 uses RDNA 3.0, a graphics-oriented architecture.

The MI350X is built on a 3 nm TSMC process node and uses the MI350 256CU chip. It has 16384 shading units and 1024 texture mapping units, but it lists zero raster operation units. It has no ray tracing cores listed. The W7800 uses the Navi 31 chip on a 5 nm TSMC process and has 4480 shading units, 280 texture mapping units, 128 raster operation units, and 70 ray tracing cores.

The MI350X uses HBM3e memory with an 8192-bit bus, while the W7800 uses GDDR6 with a 256-bit bus. The MI350X has no display outputs and no supported graphics APIs listed. The W7800 supports DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4.

The MI350X is an OAM module with dimensions of 102 mm in length and 165 mm in width. The W7800 is a dual-slot card measuring 280 mm in length, 110 mm in height, and 40 mm in width. The MI350X has no power connectors, while the W7800 uses two 8-pin connectors.

The MI350X uses a PCIe 5.0 x16 bus interface. The W7800 uses PCIe 4.0 x16. The MI350X has a base clock of 1000 MHz and a boost clock of 2200 MHz. The W7800 has a base clock of 1895 MHz and a boost clock of 2525 MHz.

# Specification Differences

The transistor counts differ substantially. The MI350X contains 185,000 million transistors, while the W7800 contains 57,700 million. The die sizes are 2380 mm² for the MI350X and 529 mm² for the W7800. Transistor density is 77.7 million per square millimeter for the MI350X and 109.1 million for the W7800.

Memory specifications diverge completely. The MI350X has 288 GB of HBM3e at 2000 MHz with 8 Gbps effective speed. The W7800 has 32 GB of GDDR6 at 2250 MHz with 18 Gbps effective speed. Bandwidth is 8.19 TB/s versus 576.0 GB/s.

Compute unit counts show 16384 shading units, 1024 TMUs, and 0 ROPs for the MI350X. The W7800 has 4480 shading units, 280 TMUs, and 128 ROPs. Pixel rates are 0 MPixel/s for the MI350X and 323.2 GPixel/s for the W7800. Texture rates are 2,252.8 GTexel/s and 707.0 GTexel/s respectively.

Power draw differs by a wide margin: 1000 W for the MI350X and 260 W for the W7800. Suggested PSU ratings are 1400 W and 600 W respectively.

Release dates are separated by roughly two years. The W7800 launched on 2023-04-12, and the MI350X launched on 2025-06-11. The W7800 has a production status of Active, while the MI350X has none listed.

The W7800 has a launch MSRP of 2,499 USD. The MI350X has no launch MSRP recorded in the database.