AMD Instinct MI325X vs NVIDIA RTX PRO 6000 Blackwell Server Comparison

Head-to-Head Benchmarks

The recorded benchmark data for these two accelerators is sparse, with only a single 3DMark Steel Nomad DX12 result available for the NVIDIA RTX PRO 6000 Blackwell Server. The AMD Instinct MI325X has no benchmark entries in the database, meaning direct head-to-head comparison scores are unavailable. The NVIDIA card’s score of 5996 places it in the 34th percentile of all GPUs, and its nearest rivals show near-identical performance: the NVIDIA GeForce GTX 770M scores 6000 (0.1% higher), the AMD Radeon RX 6400 scores 6001 (0.1% higher), the AMD FirePro W4100 scores 5987 (0.2% lower), and the NVIDIA Quadro K4000M scores 5986 (0.2% lower). This clustering indicates that in this specific DX12 workload, the RTX PRO 6000 Blackwell Server performs within a fraction of a percent of several much older and lower-tier cards, which is an unusual result for a server-class accelerator.

Without any benchmark scores for the AMD Instinct MI325X, the database cannot confirm a performance advantage for either product in measured workloads. The NVIDIA card’s lone benchmark suggests its real-time graphics performance is modest relative to its compute specifications, but the data does not support any comparative conclusion against the AMD part.

Architecture Differences

The AMD Instinct MI325X uses the Aqua Vanjaram chip built on CDNA 3.0 architecture, manufactured on a 5 nm process at TSMC. It contains 153,000 million transistors on a 1017 mm² die, yielding a transistor density of 150.4 million per mm². The NVIDIA RTX PRO 6000 Blackwell Server uses the GB202 chip on Blackwell 2.0 architecture, also manufactured on a 5 nm process at TSMC, with 92,200 million transistors on a 750 mm² die, giving a density of 122.9 million per mm². The AMD chip is therefore substantially larger in both transistor count and physical area, with a 66% higher transistor count and a 35.6% larger die.

The AMD card’s memory configuration is radically different: 256 GB of HBM3e on an 8192-bit bus delivers 6.14 TB/s of bandwidth, while the NVIDIA card uses 96 GB of GDDR7 on a 512-bit bus for 1.79 TB/s. The AMD part’s memory bandwidth is 3.43 times higher, and its capacity is 2.67 times larger. Clock speeds also differ: AMD runs a 1000 MHz base and 2100 MHz boost, while NVIDIA runs a 1590 MHz base and 2617 MHz boost. The NVIDIA card has higher clocks by 590 MHz at base and 517 MHz at boost.

The NVIDIA card includes 188 RT cores and 752 tensor cores, features the AMD part lacks entirely. The AMD card has 19,456 shading units and 1,216 texture mapping units, while the NVIDIA card has 24,064 shading units and 752 TMUs. The NVIDIA card has 192 ROPs; the AMD card reports zero ROPs and zero pixel rate. Texture rate favors AMD at 2,553.6 GTexel/s versus 1,968.0 GTexel/s, a 29.7% advantage. Pixel rate is exclusive to NVIDIA at 502.5 GPixel/s. FP32 compute is 81.72 TFLOPS for AMD and 126.0 TFLOPS for NVIDIA, a 54.2% advantage for NVIDIA. FP16 is identical to FP32 on both cards at 1:1 ratios.

The AMD card is an OAM module with no power connectors and no display outputs, while the NVIDIA card is a dual-slot PCIe card with one 16-pin connector and four DisplayPort 2.1b outputs. The AMD card’s TDP is 1000 W with a suggested PSU of 1400 W; the NVIDIA card’s TDP is 600 W with a suggested PSU of 1000 W. Both use PCIe 5.0 x16. The NVIDIA card supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4, while the AMD card reports no API support. The NVIDIA card is 267 mm long, 111 mm tall, and 40 mm wide. The AMD card’s dimensions are not recorded.

The Verdict

The data indicates that the NVIDIA RTX PRO 6000 Blackwell Server is the only one of the two with any measured benchmark result, and that result places it in the 34th percentile, surrounded by cards with nearly identical scores. The AMD Instinct MI325X has no recorded benchmarks, so the database cannot verify its real-world performance. For compute workloads, the NVIDIA card’s FP32 rating of 126.0 TFLOPS is 54.2% higher than the AMD card’s 81.72 TFLOPS, a clear mathematical advantage. The NVIDIA card also offers RT cores and tensor cores, which the AMD card does not have.

The AMD card counters with a massive memory advantage: 256 GB versus 96 GB, and 6.14 TB/s versus 1.79 TB/s. For memory-bound workloads such as large model inference or high-capacity data processing, the AMD card’s memory subsystem is decisively superior on paper. However, the absence of any benchmark data for the AMD card means the database cannot confirm whether that memory advantage translates into actual performance wins.

The NVIDIA card is the only one with an active production status, while the AMD card’s status is not recorded. The NVIDIA card’s release date is 2025-03-17, and the AMD card’s is 2024-10-09. The NVIDIA card has a successor listed as Server Rubin and a predecessor of Server Hopper; the AMD card lists Radeon Instinct as its predecessor and no successor.

Specification Differences

The two cards differ in nearly every major specification. The AMD Instinct MI325X uses the Aqua Vanjaram chip on CDNA 3.0, while the NVIDIA RTX PRO 6000 Blackwell Server uses GB202 on Blackwell 2.0. Transistor counts are 153,000 million versus 92,200 million. Die size is 1017 mm² versus 750 mm². Transistor density is 150.4M per mm² versus 122.9M per mm². Base clocks are 1000 MHz versus 1590 MHz. Boost clocks are 2100 MHz versus 2617 MHz. Memory clocks are 1500 MHz (6 Gbps effective) versus 1750 MHz (28 Gbps effective). Memory size is 256 GB versus 96 GB. Memory type is HBM3e versus GDDR7. Bus width is 8192 bit versus 512 bit. Bandwidth is 6.14 TB/s versus 1.79 TB/s. Shading units are 19,456 versus 24,064. TMUs are 1,216 versus 752. ROPs are 0 versus 192. RT cores are absent versus 188. Tensor cores are absent versus 752. Pixel rate is 0 MPixel/s versus 502.5 GPixel/s. Texture rate is 2,553.6 GTexel/s versus 1,968.0 GTexel/s. FP32 is 81.72 TFLOPS versus 126.0 TFLOPS. FP16 is 81.72 TFLOPS versus 126.0 TFLOPS. TDP is 1000 W versus 600 W. Slot width is OAM Module versus Dual-slot. Power connectors are none versus 1x 16-pin. Suggested PSU is 1400 W versus 1000 W. Display outputs are none versus 4x DisplayPort 2.1b. API support is N/A versus DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4. Dimensions are unrecorded versus 267 mm by 111 mm by 40 mm. Production status is unrecorded versus Active. Release dates are 2024-10-09 versus 2025-03-17.

FAQ

Q: Which card has higher FP32 compute performance?

A: The NVIDIA RTX PRO 6000 Blackwell Server delivers 126.0 TFLOPS FP32, which is 54.2% higher than the AMD Instinct MI325X’s 81.72 TFLOPS.

Q: How much memory bandwidth does the AMD card provide?

A: The AMD Instinct MI325X provides 6.14 TB/s of bandwidth through 256 GB of HBM3e on an 8192-bit bus.

Q: Does the NVIDIA card support ray tracing?

A: Yes, the NVIDIA RTX PRO 6000 Blackwell Server includes 188 RT cores, while the AMD Instinct MI325X has no RT cores listed.

Q: What is the power requirement difference between the two cards?

A: The AMD card has a TDP of 1000 W and a suggested PSU of 1400 W, while the NVIDIA card has a TDP of 600 W and a suggested PSU of 1000 W.

Q: Which card has display outputs?

A: The NVIDIA RTX PRO 6000 Blackwell Server has 4x DisplayPort 2.1b outputs. The AMD Instinct MI325X has no display outputs.

Q: What benchmark result exists for the NVIDIA card?

A: The NVIDIA card scored 5996 in 3DMark Steel Nomad DX12, which places it in the 34th percentile, with nearest rivals scoring within 0.2% of that figure.

Where Each One Wins

The AMD Instinct MI325X wins decisively in memory capacity and bandwidth. Its 256 GB of HBM3e and 6.14 TB/s bandwidth are far beyond the NVIDIA card’s 96 GB and 1.79 TB/s. Any workload that requires holding large datasets, such as massive model weights or high-resolution scientific data, will favor the AMD card’s memory subsystem. The AMD card also has a higher texture rate at 2,553.6 GTexel/s versus 1,968.0 GTexel/s, a 29.7% advantage. Its larger die and higher transistor count suggest a more complex compute pipeline, though no benchmark data confirms this.

The NVIDIA RTX PRO 6000 Blackwell Server wins in raw compute throughput. Its FP32 rating of 126.0 TFLOPS exceeds the AMD card by 54.2%. The inclusion of 188 RT cores and 752 tensor cores gives it capabilities the AMD card lacks entirely, making it the only option for ray-traced rendering or tensor-accelerated workloads. Its 502.5 GPixel/s pixel rate and 192 ROPs provide real rasterization throughput that the AMD card cannot offer at all, since the AMD card reports zero pixel rate and zero ROPs. The NVIDIA card also has higher base and boost clocks, active production status, and full API support for DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4. Its dual-slot form factor, 267 mm length, and single 16-pin power connector make it a standard PCIe card that can fit in conventional server chassis, whereas the AMD card uses an OAM module with no power connectors or display outputs.

The database’s only benchmark result belongs to the NVIDIA card, scoring 5996 in 3DMark Steel Nomad DX12, but that score places it in the 34th percentile and within 0.2% of much older cards like the GTX 770M and Quadro K4000M. This suggests that the NVIDIA card’s real-time graphics performance is not its primary strength, and the AMD card has no comparable recorded score. For users who need measured graphics performance, the NVIDIA card is the only one with data. For users who need maximum memory capacity and bandwidth, the AMD card’s specifications are unmatched in this comparison. The data does not support a single overall winner; the choice depends entirely on whether compute throughput or memory capacity is the priority.