AMD Instinct MI325X vs NVIDIA RTX PRO 5000 Blackwell Comparison

Head-to-Head Benchmarks

The recorded data contains no direct head-to-head benchmark results between the AMD Instinct MI325X and the NVIDIA RTX PRO 5000 Blackwell. The MI325X has no benchmark scores, average scores, or percentile rankings in the database. Its percentile versus all GPUs sits at 50, and its average benchmark score is recorded as zero. The RTX PRO 5000 Blackwell, by contrast, has three benchmark entries. Its 3DMark Steel Nomad DX12 score is 9579.5, GeekBench OpenCL score is 254116, and GeekBench Vulkan score is 282631. These results place the RTX PRO 5000 Blackwell at the 98th percentile among all GPUs, with an average benchmark score of 182109.

The nearest rivals for the RTX PRO 5000 Blackwell provide context for its standing. The NVIDIA A100 SXM4 80 GB has an average score of 183725, which is 0.9% higher than the RTX PRO 5000 Blackwell. The NVIDIA RTX 5000 Ada Generation averages 184664, 1.4% higher. The NVIDIA GeForce RTX 4090 D averages 178050, which is 2.3% lower than the RTX PRO 5000 Blackwell. The NVIDIA A100 SXM4 40 GB averages 187147, 2.7% higher. The RTX PRO 5000 Blackwell therefore sits in a tight cluster, within roughly 3% of each of these four rivals, and it is the second-lowest scoring member of that group by average score. Its strongest relative position is against the GeForce RTX 4090 D, where it holds a 2.3% lead.

The MI325X cannot be placed in this ranking because the database holds no benchmark output for it. The absence of scores does not imply equivalence; it simply means the MI325X has no recorded measurements. The RTX PRO 5000 Blackwell has a full set of application-level results, while the MI325X has none. Any comparison of their benchmark performance must rely on architectural and specification differences rather than measured scores.

The Verdict

The data supports a clear separation of roles. The RTX PRO 5000 Blackwell is the only one of the two with recorded benchmark results, and those results place it in the 98th percentile of all GPUs. Its average benchmark score of 182109 and its lead of 2.3% over the GeForce RTX 4090 D indicate a strong, measurable performer in general compute workloads. The MI325X has no benchmark data, no average score, and a 50th percentile ranking that reflects its unmeasured status rather than its capability.

For workloads that require standardized benchmark verification, the RTX PRO 5000 Blackwell is the only option with data backing. It also supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4, which makes it usable across a broad range of graphics and compute APIs. The MI325X lists no API support, no display outputs, and no graphics pipeline rates. The RTX PRO 5000 Blackwell has 110 RT cores and 440 tensor cores, while the MI325X lists none. The NVIDIA card has a pixel rate of 380.3 GPixel/s and a texture rate of 1045.9 GTexel/s, whereas the MI325X pixel rate is zero and its texture rate is 2553.6 GTexel/s.

The MI325X has substantial raw compute resources. Its 19,456 shading units, 1,216 texture mapping units, and 256 GB of HBM3e memory with 6.14 TB/s bandwidth are far larger than the RTX PRO 5000 Blackwell's figures. Its FP32 throughput of 81.72 TFLOPS exceeds the NVIDIA card's 66.94 TFLOPS. The MI325X also has a larger die at 1017 mm² versus 750 mm², and more transistors at 153,000 million versus 92,200 million. These are hardware specifications that suggest high compute capacity, but without benchmark scores, the database cannot confirm how that capacity translates into performance. The verdict from the data is straightforward: the RTX PRO 5000 Blackwell is the verified performer, and the MI325X is an unmeasured compute accelerator with a very large memory pool and higher theoretical throughput.

Architecture Differences

The two accelerators use different architectures from different vendors. The AMD Instinct MI325X uses CDNA 3.0, built on the Aqua Vanjaram chip, while the NVIDIA RTX PRO 5000 Blackwell uses Blackwell 2.0, built on the GB202 chip. Both are manufactured on a 5 nm process at TSMC, but the die sizes differ substantially. The MI325X die measures 1017 mm² and contains 153,000 million transistors, giving a transistor density of 150.4 million per mm². The RTX PRO 5000 Blackwell die measures 750 mm² and contains 92,200 million transistors, for a density of 122.9 million per mm². The AMD chip is larger, denser, and carries roughly 66% more transistors.

Memory architecture is another major divergence. The MI325X uses 256 GB of HBM3e on an 8192-bit bus, delivering 6.14 TB/s of bandwidth. The RTX PRO 5000 Blackwell uses 48 GB of GDDR7 on a 384-bit bus, delivering 1.34 TB/s. The MI325X has more than five times the memory capacity and more than four and a half times the bandwidth. The clock speeds also differ. The MI325X has a base clock of 1000 MHz and a boost clock of 2100 MHz, with memory clocked at 1500 MHz (6 Gbps effective). The RTX PRO 5000 Blackwell has a base clock of 1740 MHz, a boost clock of 2377 MHz, and memory clocked at 1750 MHz (28 Gbps effective). The NVIDIA card runs at higher clock frequencies, while the AMD card relies on its wider memory bus and larger memory pool.

Compute resources are organized differently. The MI325X has 19,456 shading units and 1,216 TMUs, with no ROPs, no RT cores, and no tensor cores listed. The RTX PRO 5000 Blackwell has 14,080 shading units, 440 TMUs, 160 ROPs, 110 RT cores, and 440 tensor cores. The MI325X has a texture rate of 2553.6 GTexel/s, which is higher than the RTX PRO 5000 Blackwell's 1045.9 GTexel/s. The RTX PRO 5000 Blackwell has a pixel rate of 380.3 GPixel/s, while the MI325X is listed at 0 MPixel/s, consistent with its lack of display outputs. The MI325X has no display outputs at all, while the RTX PRO 5000 Blackwell has 4x DisplayPort 2.1b.

Power and form factor differences are pronounced. The MI325X has a TDP of 1000 W, uses an OAM module slot, has no power connectors listed, and suggests a 1400 W power supply. The RTX PRO 5000 Blackwell has a TDP of 300 W, uses a dual-slot form factor, has one 16-pin power connector, and suggests a 700 W power supply. The NVIDIA card is a standard PCIe add-in card measuring 267 mm by 111 mm by 40 mm, while the AMD card is an OAM module with no dimensions listed. The RTX PRO 5000 Blackwell is an active production product, released on March 17, 2025, with a launch MSRP of 5,099 USD. The MI325X was released on October 9, 2024, and its production status is not recorded.

API support also separates the two. The RTX PRO 5000 Blackwell supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4. The MI325X lists N/A for all three APIs. This aligns with the MI325X being an accelerator without display or graphics output functionality, while the RTX PRO 5000 Blackwell is a full workstation graphics card.

FAQ

Q: Which GPU has more memory bandwidth?

A: The AMD Instinct MI325X has 6.14 TB/s of bandwidth from 256 GB of HBM3e on an 8192-bit bus. The NVIDIA RTX PRO 5000 Blackwell has 1.34 TB/s from 48 GB of GDDR7 on a 384-bit bus.

Q: Which GPU has higher FP32 compute throughput?

A: The MI325X delivers 81.72 TFLOPS of FP32, while the RTX PRO 5000 Blackwell delivers 66.94 TFLOPS. The MI325X is higher by roughly 22%.

Q: Does the NVIDIA card support ray tracing?

A: Yes, the RTX PRO 5000 Blackwell lists 110 RT cores and 440 tensor cores. The MI325X lists no RT cores or tensor cores.

Q: What is the power consumption difference?

A: The MI325X has a TDP of 1000 W and suggests a 1400 W power supply. The RTX PRO 5000 Blackwell has a TDP of 300 W and suggests a 700 W power supply.

Q: Which GPU has recorded benchmark scores?

A: Only the RTX PRO 5000 Blackwell has benchmark scores in the database: 9579.5 in 3DMark Steel Nomad DX12, 254116 in GeekBench OpenCL, and 282631 in GeekBench Vulkan. The MI325X has no recorded benchmark scores.

Q: What form factor does each GPU use?

A: The MI325X uses an OAM module with no power connectors and no display outputs. The RTX PRO 5000 Blackwell is a dual-slot card with one 16-pin power connector and 4x DisplayPort 2.1b outputs.

Where Each One Wins

The RTX PRO 5000 Blackwell wins in every measured category because it is the only one with measured data. Its 98th percentile ranking, average score of 182109, and 2.3% lead over the GeForce RTX 4090 D give it a verified position in the upper tier of GPUs. It wins on API compatibility, supporting DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4, while the MI325X supports none. It wins on graphics output with 4x DisplayPort 2.1b, on pixel throughput with 380.3 GPixel/s, and on power efficiency with a 300 W TDP versus 1000 W. It also wins on availability, with an active production status and a specific release date of March 17, 2025.

The MI325X wins on raw hardware specifications. Its 256 GB memory capacity and 6.14 TB/s bandwidth are far beyond the RTX PRO 5000 Blackwell's 48 GB and 1.34 TB/s. Its FP32 throughput of 81.72 TFLOPS exceeds the NVIDIA card's 66.94 TFLOPS, and its FP16 throughput matches its FP32 figure at 81.72 TFLOPS. Its texture rate of 2553.6 GTexel/s is more than double the RTX PRO 5000 Blackwell's 1045.9 GTexel/s. Its die is larger at 1017 mm², and its transistor count of 153,000 million is substantially higher than 92,200 million. These wins are specification-based, not benchmark-based.

The database therefore shows two different kinds of products. The RTX PRO 5000 Blackwell is a verified, widely compatible workstation GPU with strong benchmark results and a standard PCIe form factor. The MI325X is a high-capacity compute accelerator with enormous memory and bandwidth, but no recorded benchmark results, no API support, no display outputs, and a much higher power requirement. Each wins in its own domain: the NVIDIA card in measured performance and platform compatibility, the AMD card in memory capacity, bandwidth, and theoretical compute throughput.