AMD Instinct MI325X vs NVIDIA RTX PRO 4500 Blackwell Comparison

Where Each One Wins

The recorded data splits these two accelerators into entirely different usage domains. AMD Instinct MI325X has no benchmark entries in the database, so the comparison rests on architectural and specification-level differences rather than measured performance scores. NVIDIA RTX PRO 4500 Blackwell carries nine benchmark results, with its strongest showing in compute-oriented workloads. PassMark G3D returns 33360 points, while PassMark GPU Compute reaches 19255 points. The Geekbench Vulkan result of 221768 indicates strong graphics API performance, and 3DMark Steel Nomad DX12 scores 7025 points.

The AMD side posts zero wins because no benchmark data exists for it. The NVIDIA side posts zero wins in the head-to-head field for the same reason. The absence of measured data for the MI325X means the database cannot confirm any workload where the AMD part would outperform the NVIDIA part. What the data does show is that the RTX PRO 4500 occupies the 76th percentile among all GPUs, while the MI325X sits at the 50th percentile. The NVIDIA card also has an average benchmark score of 31532, placing it within 0.5% of the NVIDIA TITAN RTX (31676) and 1.1% above the Intel Arc Pro A30M (31894, delta -1.1%).

The MI325X instead wins on capacity and throughput specifications. It delivers 256 GB of HBM3e memory, 8192-bit bus width, and 6.14 TB/s bandwidth. These figures target memory-bound workloads where dataset size and memory bandwidth dominate. The RTX PRO 4500 uses 32 GB of GDDR7 on a 256-bit bus with 896.0 GB/s bandwidth. The AMD card provides 8 times the memory capacity and roughly 6.85 times the bandwidth. The NVIDIA card provides measured graphics performance and a full display output suite. The AMD card provides no display outputs at all.

Architecture Differences

The two chips share a 5 nm TSMC process node but diverge sharply beyond that. AMD uses the Aqua Vanjaram chip with CDNA 3.0 architecture, while NVIDIA uses the GB203 chip with Blackwell 2.0 architecture. Transistor counts differ by a factor of roughly 3.35: AMD packs 153,000 million transistors on a 1017 mm² die, yielding 150.4 million transistors per square millimeter. NVIDIA packs 45,600 million transistors on a 378 mm² die, yielding 120.6 million transistors per square millimeter. The AMD die is 2.69 times larger physically.

Shading unit counts follow the same pattern. AMD lists 19456 shading units, 1216 texture mapping units, and no raster operations pipelines. NVIDIA lists 10496 shading units, 328 TMUs, and 112 ROPs. The AMD texture rate reaches 2553.6 GTexel/s versus 789.5 GTexel/s for NVIDIA. NVIDIA provides 82 RT cores and 328 tensor cores; AMD lists no RT cores and no tensor cores in the database. NVIDIA supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4. AMD lists N/A for all three APIs.

Clock behavior also differs. AMD runs at a 1000 MHz base and 2100 MHz boost, with memory at 1500 MHz (6 Gbps effective). NVIDIA runs at a 1635 MHz base and 2407 MHz boost, with memory at 1750 MHz (28 Gbps effective). The NVIDIA boost clock is 14.6% higher than the AMD boost clock. FP32 and FP16 compute both follow a 1:1 ratio on both cards: AMD delivers 81.72 TFLOPS in each, NVIDIA delivers 50.53 TFLOPS in each. The AMD FP32 figure is 61.7% higher than the NVIDIA figure.

Power and physical design differ completely. AMD draws 1000 W TDP with a suggested 1400 W PSU, no power connectors (OAM module), and no display outputs. NVIDIA draws 200 W TDP with a suggested 550 W PSU, one 16-pin connector, dual-slot width, and 4x DisplayPort 2.1b outputs. The NVIDIA card measures 267 mm in length, 111 mm in height, and 40 mm in width. The AMD card has no recorded dimensions.

The Verdict

The data supports a simple split. For compute workloads that demand massive memory capacity and bandwidth, the AMD Instinct MI325X is the only option in this pair that provides 256 GB of HBM3e and 6.14 TB/s of bandwidth. Its 81.72 TFLOPS FP32 and FP16 figures exceed the NVIDIA card by 61.7%. Its 2553.6 GTexel/s texture rate exceeds the NVIDIA card by roughly 3.23 times. The AMD part has no display outputs, no graphics API support, and a 1000 W TDP, so it belongs in a server or accelerator chassis.

For workstation graphics, rendering, and any workload that needs a physical display, the NVIDIA RTX PRO 4500 Blackwell is the only choice with measured benchmark results. It holds the 76th percentile among all GPUs, delivers 33360 in PassMark G3D, and 221768 in Geekbench Vulkan. Its 4x DisplayPort 2.1b outputs, DirectX 12 Ultimate support, and 200 W TDP make it a conventional workstation card. The 82 RT cores and 328 tensor cores provide hardware acceleration paths that the AMD card does not list. The 32 GB GDDR7 frame buffer is smaller but still substantial for graphics work.

The database shows 0 wins for each side in the head-to-head field because no shared benchmark results exist. Users who need measured performance should treat the RTX PRO 4500 as the verified option. Users who need memory scale should treat the MI325X as the specification-driven option.

FAQ

Q: Which card has more memory bandwidth?

A: The AMD Instinct MI325X provides 6.14 TB/s of bandwidth through 256 GB of HBM3e on an 8192-bit bus. The NVIDIA RTX PRO 4500 provides 896.0 GB/s through 32 GB of GDDR7 on a 256-bit bus.

Q: Does the AMD card support DirectX?

A: No. The database lists DirectX, OpenGL, and Vulkan support as N/A for the AMD Instinct MI325X. The NVIDIA RTX PRO 4500 supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4.

Q: What is the performance percentile of each card?

A: The AMD Instinct MI325X sits at the 50th percentile among all GPUs with an average benchmark score of 0. The NVIDIA RTX PRO 4500 sits at the 76th percentile with an average benchmark score of 31532.

Q: Which card has more shading units?

A: The AMD Instinct MI325X has 19456 shading units and 1216 TMUs. The NVIDIA RTX PRO 4500 has 10496 shading units and 328 TMUs. The AMD card also has a higher texture rate at 2553.6 GTexel/s versus 789.5 GTexel/s.

Q: Can either card output to displays?

A: Only the NVIDIA RTX PRO 4500 can. It has 4x DisplayPort 2.1b outputs. The AMD Instinct MI325X lists no display outputs.

Q: What are the power requirements?

A: The AMD Instinct MI325X has a 1000 W TDP and a suggested 1400 W PSU. The NVIDIA RTX PRO 4500 has a 200 W TDP and a suggested 550 W PSU.

Head-to-Head Benchmarks

No shared benchmark results exist in the database for these two cards. The headToHeadBenchmarks field is empty, and both wins fields read 0. The comparison therefore relies on the NVIDIA card's standalone benchmarks and the AMD card's specification sheet.

The NVIDIA RTX PRO 4500 shows its strongest absolute results in Geekbench Vulkan at 221768 and PassMark G3D at 33360. Its PassMark GPU Compute score of 19255 indicates compute throughput, while its 3DMark Steel Nomad DX12 score of 7025 shows modern DirectX 12 rendering capability. The PassMark DirectX 9 score of 397, DirectX 11 score of 320, and DirectX 10 score of 204 reflect older API paths. The PassMark G2D score of 1336 covers 2D operations. These nine benchmarks place the card at the 76th percentile overall.

The AMD Instinct MI325X has no benchmark entries, so the database cannot assign it a measured score. Its average benchmark score is 0, and its percentile is 50. The only quantitative comparison points are specifications: FP32 at 81.72 TFLOPS, FP16 at 81.72 TFLOPS, texture rate at 2553.6 GTexel/s, and memory bandwidth at 6.14 TB/s. Against the NVIDIA card's 50.53 TFLOPS FP32, 789.5 GTexel/s texture rate, and 896.0 GB/s bandwidth, the AMD part leads on raw throughput by 61.7% in FP32, by roughly 3.23 times in texture rate, and by roughly 6.85 times in memory bandwidth.

The NVIDIA card counters with higher clocks: 2407 MHz boost versus 2100 MHz, a 14.6% advantage. It also has 112 ROPs and a 269.6 GPixel/s pixel rate, while the AMD card lists 0 ROPs and 0 MPixel/s. The NVIDIA card's 82 RT cores and 328 tensor cores provide dedicated hardware that the AMD card does not list. The bus interface matches at PCIe 5.0 x16 for both.

Specification Differences

| Specification | AMD Instinct MI325X | NVIDIA RTX PRO 4500 Blackwell |

|---|---|---|

| Chip | Aqua Vanjaram | GB203 |

| Architecture | CDNA 3.0 | Blackwell 2.0 |

| Transistors | 153,000 million | 45,600 million |

| Die Size | 1017 mm² | 378 mm² |

| Transistor Density | 150.4M / mm² | 120.6M / mm² |

| Base Clock | 1000 MHz | 1635 MHz |

| Boost Clock | 2100 MHz | 2407 MHz |

| Memory Size | 256 GB | 32 GB |

| Memory Type | HBM3e | GDDR7 |

| Memory Bus Width | 8192 bit | 256 bit |

| Memory Bandwidth | 6.14 TB/s | 896.0 GB/s |

| Shading Units | 19456 | 10496 |

| TMUs | 1216 | 328 |

| ROPs | 0 | 112 |

| RT Cores | None listed | 82 |

| Tensor Cores | None listed | 328 |

| Pixel Rate | 0 MPixel/s | 269.6 GPixel/s |

| Texture Rate | 2553.6 GTexel/s | 789.5 GTexel/s |

| FP32 | 81.72 TFLOPS | 50.53 TFLOPS |

| FP16 | 81.72 TFLOPS (1:1) | 50.53 TFLOPS (1:1) |

| TDP | 1000 W | 200 W |

| Slot Width | OAM Module | Dual-slot |

| Power Connectors | None | 1x 16-pin |

| Suggested PSU | 1400 W | 550 W |

| Display Outputs | No outputs | 4x DisplayPort 2.1b |

| DirectX | N/A | 12 Ultimate (12_2) |

| OpenGL | N/A | 4.6 |

| Vulkan | N/A | 1.4 |

| Release Date | 2024-10-09 | 2025-03-17 |

| Production Status | Not listed | Active |