AMD Instinct MI325X vs NVIDIA GeForce RTX 4080 SUPER Comparison

Head-to-Head Benchmarks

The database contains no direct head-to-head benchmark results between the AMD Instinct MI325X and the NVIDIA GeForce RTX 4080 SUPER. The MI325X has no recorded benchmark scores, an average benchmark score of 0, and sits at the 50th percentile among all GPUs. The RTX 4080 SUPER, by contrast, has a substantial catalog of test results.

The RTX 4080 SUPER delivers an average benchmark score of 54,209 across its recorded tests. Its closest rival, the NVIDIA GeForce RTX 4080, scores 54,247, a delta of -0.1%, meaning the SUPER variant trails the non-SUPER model by a hair. The AMD Radeon Pro W5700X posts 54,828, putting it 1.1% ahead of the RTX 4080 SUPER. The AMD Radeon RX 6750 GRE 12 GB reaches 55,698, a 2.7% lead, and the AMD Radeon 8060S scores 55,757, 2.8% ahead. These deltas show the RTX 4080 SUPER performing slightly below several rivals in aggregate scoring, but the differences are small, within a few percentage points.

Individual benchmark results for the RTX 4080 SUPER show its strongest areas. In Geekbench Vulkan, it scores 260,075, while its Geekbench OpenCL result is 219,065. PassMark G3D yields 34,245, and PassMark GPU Compute produces 19,822. DirectX tests are more modest: PassMark DirectX 11 scores 301, DirectX 9 scores 381, DirectX 10 scores 193, and DirectX 12 scores 134. The PassMark G2D score is 1,270. The 3DMark Steel Nomad DX12 test returns 6,600.

The MI325X cannot be compared on any of these metrics because no benchmark data exists for it. Its percentile ranking of 50 reflects the absence of recorded performance, not a measured result. The RTX 4080 SUPER, at the 86th percentile, sits well above the midpoint, indicating that its recorded scores place it among the higher-performing GPUs in the database.

Architecture Differences

The two accelerators share a 5 nm process node and TSMC as the foundry, but the similarities end there. The MI325X uses the CDNA 3.0 architecture with the Aqua Vanjaram chip, while the RTX 4080 SUPER uses Ada Lovelace with the AD103 chip. The MI325X is built for compute workloads in the Instinct (MIx) generation, whereas the RTX 4080 SUPER belongs to the GeForce 40 series.

Transistor counts differ enormously. The MI325X packs 153,000 million transistors on a 1017 mm² die, yielding a transistor density of 150.4M per mm². The RTX 4080 SUPER has 45,900 million transistors on a 379 mm² die, with a density of 121.1M per mm². The MI325X die is nearly three times larger and holds more than three times the transistors.

Memory architecture is fundamentally different. The MI325X uses 256 GB of HBM3e across an 8192-bit bus, delivering 6.14 TB/s of bandwidth. The RTX 4080 SUPER uses 16 GB of GDDR6X on a 256-bit bus, delivering 736.3 GB/s. The MI325X has over eight times the memory capacity and roughly eight times the bandwidth.

Compute resources diverge sharply. The MI325X has 19,456 shading units and 1,216 texture mapping units, but zero ROPs and a pixel rate of 0 MPixel/s. The RTX 4080 SUPER has 10,240 shading units, 320 TMUs, and 112 ROPs, with a pixel rate of 285.6 GPixel/s. The MI325X has no RT cores or tensor cores listed, while the RTX 4080 SUPER has 80 RT cores and 320 tensor cores.

Clock speeds favor the NVIDIA part. The MI325X runs at a 1000 MHz base and 2100 MHz boost, while the RTX 4080 SUPER runs at 2295 MHz base and 2550 MHz boost. Memory clocks also differ: 1500 MHz with 6 Gbps effective for the MI325X versus 1438 MHz with 23 Gbps effective for the RTX 4080 SUPER.

The MI325X posts higher raw throughput in several metrics. Its FP32 performance is 81.72 TFLOPS, and FP16 is also 81.72 TFLOPS at a 1:1 ratio. The RTX 4080 SUPER delivers 52.22 TFLOPS in both FP32 and FP16. Texture rate for the MI325X is 2,553.6 GTexel/s, versus 816.0 GTexel/s for the RTX 4080 SUPER.

Power and interface requirements differ just as much. The MI325X has a TDP of 1000 W and requires a 1400 W suggested PSU. It uses an OAM module form factor with no power connectors and no display outputs. The RTX 4080 SUPER has a 320 W TDP, a 700 W suggested PSU, a triple-slot design, and a single 16-pin power connector. It offers 1x HDMI 2.1 and 3x DisplayPort 1.4a outputs. The MI325X uses PCIe 5.0 x16, while the RTX 4080 SUPER uses PCIe 4.0 x16.

API support is absent on the MI325X, with DirectX, OpenGL, and Vulkan all listed as N/A. The RTX 4080 SUPER supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4.

Where Each One Wins

The RTX 4080 SUPER wins on every measurable benchmark in the database because it is the only one with recorded results. Its 86th percentile ranking and average score of 54,209 place it among the top tier of GPUs in the database. The MI325X, with no benchmarks and a 50th percentile, cannot claim any measured performance advantage.

For gaming and consumer graphics, the RTX 4080 SUPER is the clear choice by the numbers. It has ROPs, RT cores, tensor cores, display outputs, and full API support. Its pixel rate of 285.6 GPixel/s and texture rate of 816.0 GTexel/s give it the rendering pipeline needed for real-time graphics. The 16 GB GDDR6X memory and 736.3 GB/s bandwidth are sufficient for high-resolution gaming workloads.

For compute-oriented tasks, the MI325X holds the theoretical advantage based on raw specifications. Its 256 GB HBM3e memory, 6.14 TB/s bandwidth, 81.72 TFLOPS FP32, and 2,553.6 GTexel/s texture rate dwarf the RTX 4080 SUPER in raw throughput. The absence of display outputs and API support indicates it is not intended for graphics output, but for data center and HPC workloads where massive memory capacity and bandwidth matter more than rendering features.

The MI325X also wins on memory capacity and bandwidth outright. With 256 GB versus 16 GB and 6.14 TB/s versus 736.3 GB/s, the MI325X is designed for models and datasets that would exhaust the RTX 4080 SUPER's memory entirely. The 8192-bit bus width is unmatched by any consumer GPU.

Specification Differences

| Specification | AMD Instinct MI325X | NVIDIA GeForce RTX 4080 SUPER |

|---|---|---|

| Architecture | CDNA 3.0 | Ada Lovelace |

| Chip | Aqua Vanjaram | AD103 |

| Generation | Instinct (MIx) | GeForce 40 |

| Process Node | 5 nm | 5 nm |

| Transistors | 153,000 million | 45,900 million |

| Die Size | 1017 mm² | 379 mm² |

| Transistor Density | 150.4M / mm² | 121.1M / mm² |

| Base Clock | 1000 MHz | 2295 MHz |

| Boost Clock | 2100 MHz | 2550 MHz |

| Memory Clock | 1500 MHz, 6 Gbps effective | 1438 MHz, 23 Gbps effective |

| Memory Size | 256 GB | 16 GB |

| Memory Type | HBM3e | GDDR6X |

| Memory Bus Width | 8192 bit | 256 bit |

| Memory Bandwidth | 6.14 TB/s | 736.3 GB/s |

| Shading Units | 19,456 | 10,240 |

| TMUs | 1,216 | 320 |

| ROPs | 0 | 112 |

| RT Cores | N/A | 80 |

| Tensor Cores | N/A | 320 |

| Pixel Rate | 0 MPixel/s | 285.6 GPixel/s |

| Texture Rate | 2,553.6 GTexel/s | 816.0 GTexel/s |

| FP32 | 81.72 TFLOPS | 52.22 TFLOPS |

| FP16 | 81.72 TFLOPS (1:1) | 52.22 TFLOPS (1:1) |

| TDP | 1000 W | 320 W |

| Slot Width | OAM Module | Triple-slot |

| Power Connectors | None | 1x 16-pin |

| Suggested PSU | 1400 W | 700 W |

| Bus Interface | PCIe 5.0 x16 | PCIe 4.0 x16 |

| Display Outputs | No outputs | 1x HDMI 2.1, 3x DisplayPort 1.4a |

| DirectX | N/A | 12 Ultimate (12_2) |

| OpenGL | N/A | 4.6 |

| Vulkan | N/A | 1.4 |

| Dimensions | N/A | 310 mm x 140 mm x 61 mm |

| Release Date | 2024-10-09 | 2024-01-30 |

| Production Status | N/A | End-of-life |

| Predecessor | Radeon Instinct | GeForce 30 |

| Successor | N/A | GeForce 50 |

FAQ

Q: Which GPU has more memory?

A: The AMD Instinct MI325X has 256 GB of HBM3e memory, compared to 16 GB of GDDR6X on the NVIDIA GeForce RTX 4080 SUPER.

Q: What is the memory bandwidth difference?

A: The MI325X delivers 6.14 TB/s over an 8192-bit bus, while the RTX 4080 SUPER delivers 736.3 GB/s over a 256-bit bus.

Q: Which card has higher FP32 compute performance?

A: The MI325X reaches 81.72 TFLOPS in FP32, while the RTX 4080 SUPER reaches 52.22 TFLOPS.

Q: Does the RTX 4080 SUPER support ray tracing?

A: Yes, the RTX 4080 SUPER has 80 RT cores and 320 tensor cores. The MI325X lists no RT or tensor cores.

Q: Which GPU has display outputs?

A: Only the RTX 4080 SUPER has display outputs, offering 1x HDMI 2.1 and 3x DisplayPort 1.4a. The MI325X has no outputs.

Q: What is the power requirement for each?

A: The MI325X has a 1000 W TDP and suggests a 1400 W PSU. The RTX 4080 SUPER has a 320 W TDP and suggests a 700 W PSU.

The Verdict

The data separates these two clearly by intended use. The NVIDIA GeForce RTX 4080 SUPER is the only one with benchmark results, and those results place it at the 86th percentile with an average score of 54,209, within a few percentage points of its nearest rivals. It supports DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4, has display outputs, and fits in a triple-slot consumer form factor with a 16-pin power connector. Its 320 W TDP and 700 W suggested PSU make it practical for a standard desktop build.

The AMD Instinct MI325X has no recorded benchmarks and no graphics pipeline, with zero ROPs, no pixel rate, and no API support. It is an OAM module with no power connectors and no display outputs. Its specifications target compute density: 256 GB of HBM3e, 6.14 TB/s bandwidth, 81.72 TFLOPS FP32, and 19,456 shading units. The 1000 W TDP and 1400 W suggested PSU indicate a data center installation, not a consumer workstation.

Buyers should choose based on workload. For gaming, rendering, or any task requiring display output and graphics APIs, the RTX 4080 SUPER is the only viable option between the two. Its benchmark scores confirm solid performance relative to peers. For large-scale compute, machine learning training, or memory-bound workloads where capacity and bandwidth dominate, the MI325X offers specifications that the RTX 4080 SUPER cannot match, despite the absence of measured benchmark data to validate its real-world performance.