AMD Instinct MI325X vs NVIDIA GeForce RTX 4080 Mobile Comparison

FAQ

Q: What are the two products compared here?

A: The AMD Instinct MI325X is a data center accelerator built on CDNA 3.0 architecture, while the NVIDIA GeForce RTX 4080 Mobile is a laptop GPU from the GeForce 40-series based on Ada Lovelace.

Q: How do their benchmark scores compare?

A: The NVIDIA RTX 4080 Mobile has recorded benchmark scores including 159575 in Geekbench OpenCL, 145807 in Geekbench Vulkan, and 24926 in Passmark G3D. The AMD Instinct MI325X has no benchmark entries in the database, with an average score of 0 and a percentile ranking of 50 compared to the RTX 4080 Mobile's 81st percentile.

Q: Which GPU has more memory and bandwidth?

A: The AMD Instinct MI325X carries 256 GB of HBM3e memory on a 8192-bit bus, delivering 6.14 TB/s bandwidth. The NVIDIA RTX 4080 Mobile has 12 GB of GDDR6 on a 192-bit bus with 432.0 GB/s bandwidth.

Q: How do their compute capabilities differ?

A: The AMD Instinct MI325X offers 19456 shading units and 81.72 TFLOPS FP32 performance. The NVIDIA RTX 4080 Mobile delivers 7424 shading units and 24.72 TFLOPS FP32. The AMD part also includes 1216 TMUs, while the NVIDIA part has 232 TMUs and 80 ROPs.

Q: What are the power requirements?

A: The AMD Instinct MI325X has a 1000 W TDP and requires a 1400 W suggested PSU. The NVIDIA RTX 4080 Mobile has a 110 W TDP, which is approximately one-ninth the power envelope of the AMD accelerator.

Q: What is the production status of each?

A: The NVIDIA GeForce RTX 4080 Mobile is listed as Active production, released on 2023-01-02. The AMD Instinct MI325X release date is 2024-10-09, with no production status field recorded in the database.

The Verdict

The data presents two devices serving entirely different roles. The AMD Instinct MI325X is a massive accelerator with 153,000 million transistors on a 1017 mm² die, designed for high-throughput compute workloads. The NVIDIA GeForce RTX 4080 Mobile is a compact laptop GPU with 35,800 million transistors on a 294 mm² die, built for portable graphics.

The NVIDIA part has actual benchmark results, an 81st percentile ranking, and an average score of 38135. The AMD part has zero recorded benchmarks and sits at the 50th percentile by default. For any workload requiring validated graphics or compute performance from the database, the RTX 4080 Mobile is the only option with measurable results.

However, the AMD MI325X delivers 256 GB of HBM3e memory with 6.14 TB/s bandwidth, figures that dwarf the RTX 4080 Mobile's 12 GB and 432.0 GB/s. The AMD accelerator also provides 81.72 TFLOPS FP32, which is 3.3 times the 24.72 TFLOPS of the NVIDIA part. For memory-bound or raw-throughput tasks, the MI325X's specifications indicate a fundamentally different capability class.

The RTX 4080 Mobile supports DirectX 12 Ultimate, OpenGL 4.6, and Vulkan 1.4, while the MI325X has no display outputs and no API support listed. The NVIDIA part includes 58 RT cores and 232 tensor cores, features absent from the AMD specification sheet. The MI325X cannot drive a display, while the RTX 4080 Mobile's outputs are described as portable device dependent.

Head-to-Head Benchmarks

The database contains no head-to-head benchmark entries between the AMD Instinct MI325X and the NVIDIA GeForce RTX 4080 Mobile. The wins tally shows 0 for each side. The AMD accelerator has no benchmark array populated, meaning no Geekbench, Passmark, or other test scores exist for comparison.

The NVIDIA RTX 4080 Mobile's recorded scores provide context for its performance tier. Its Geekbench OpenCL score of 159575 and Vulkan score of 145807 indicate strong compute throughput in those specific tests. Passmark results show 24926 in G3D, 11191 in GPU compute, and lower scores in older DirectX tests: 286 in DirectX 9, 244 in DirectX 11, 157 in DirectX 10, and 96 in DirectX 12. The Passmark G2D score sits at 929.

The nearest rivals data for the RTX 4080 Mobile places it in a tight cluster. The NVIDIA GeForce MX570 scores 38299, a delta of -0.4 percent. The GeForce RTX 5080 Mobile scores 38349, also -0.6 percent. The desktop GeForce RTX 4070 scores 37648, which is 1.3 percent lower, and the Tesla P4 scores 37628, also 1.3 percent lower. The RTX 4080 Mobile's average of 38135 sits between these values, indicating near parity with its closest competitors in aggregate scoring.

Specification Differences

The AMD Instinct MI325X uses a 5 nm process at TSMC with 153,000 million transistors on a 1017 mm² die, achieving a transistor density of 150.4 million per square millimeter. The NVIDIA RTX 4080 Mobile also uses TSMC 5 nm but packs 35,800 million transistors on a 294 mm² die, for a density of 121.8 million per square millimeter.

Memory configurations diverge sharply. The MI325X uses HBM3e with 256 GB capacity, 8192-bit bus width, and 6.14 TB/s bandwidth. The RTX 4080 Mobile uses GDDR6 with 12 GB capacity, 192-bit bus width, and 432.0 GB/s bandwidth.

Clock speeds differ in character. The MI325X has a 1000 MHz base and 2100 MHz boost, with memory at 1500 MHz running 6 Gbps effective. The RTX 4080 Mobile has a 1290 MHz base and 1665 MHz boost, with memory at 2250 MHz running 18 Gbps effective. The NVIDIA part boosts lower but starts higher.

The MI325X lists pixel rate as 0 MPixel/s and ROPs as 0, reflecting its lack of rasterization hardware. The RTX 4080 Mobile has 80 ROPs and a 133.2 GPixel/s pixel rate. Texture rates show 2,553.6 GTexel/s for the AMD part versus 386.3 GTexel/s for NVIDIA.

Power and physical specifications differ enormously. The MI325X draws 1000 W TDP with a 1400 W suggested PSU, occupies an OAM Module slot, and uses PCIe 5.0 x16. The RTX 4080 Mobile draws 110 W, is an IGP form factor, and uses PCIe 4.0 x16.

Architecture Differences

The MI325X uses CDNA 3.0 architecture on the Aqua Vanjaram chip, a design optimized for data center compute. It belongs to the Instinct (MIx) generation. The RTX 4080 Mobile uses Ada Lovelace architecture on the AD104 chip, part of the GeForce 40 Mobile generation.

Compute resources show the MI325X's scale advantage: 19456 shading units and 1216 TMUs versus 7424 shading units and 232 TMUs. FP32 throughput reaches 81.72 TFLOPS on AMD versus 24.72 TFLOPS on NVIDIA, with both running 1:1 FP16 ratios.

The RTX 4080 Mobile includes 58 RT cores and 232 tensor cores, enabling hardware ray tracing and tensor acceleration. The MI325X specification lists no RT or tensor core counts. The NVIDIA part supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4. The MI325X lists N/A for all APIs and has no display outputs.

The MI325X has no power connectors listed and no display outputs, confirming its purpose as an accelerator in a server chassis. The RTX 4080 Mobile has no power connectors either, relying on laptop power delivery, and its display outputs are portable device dependent.

Transistor counts reflect design philosophy. The MI325X uses 153,000 million transistors, more than four times the RTX 4080 Mobile's 35,800 million. Die size tells a similar story: 1017 mm² versus 294 mm². The density difference, 150.4M per mm² versus 121.8M per mm², indicates the AMD chip packs transistors more tightly despite its larger physical footprint.

Where Each One Wins

The NVIDIA GeForce RTX 4080 Mobile wins in any scenario requiring verified benchmark data. Its average score of 38135 with an 81st percentile ranking demonstrates measurable performance, while the MI325X has no recorded scores. The RTX 4080 Mobile also wins for graphics workloads: it has ROPs, RT cores, tensor cores, display outputs, and full API support including DirectX 12 Ultimate and Vulkan 1.4.

The RTX 4080 Mobile wins on efficiency in portable contexts. Its 110 W TDP fits within laptop power budgets, and its predecessor and successor lines, GeForce 30 Mobile and GeForce 50 Mobile, show it belongs to an established mobile product family. The MI325X's 1000 W TDP and 1400 W suggested PSU place it firmly in rack-mounted server territory.

The AMD Instinct MI325X wins on raw capacity and throughput specifications. Its 256 GB HBM3e memory with 6.14 TB/s bandwidth provides 21 times the capacity and over 14 times the bandwidth of the RTX 4080 Mobile. The 81.72 TFLOPS FP32 figure exceeds the NVIDIA part by 57 TFLOPS, and the texture rate of 2,553.6 GTexel/s is over six times higher.

The MI325X wins for memory-bound compute tasks where capacity and bandwidth dominate, such as large model inference or data processing. Its 8192-bit memory bus and 5 nm TSMC fabrication with 153,000 million transistors indicate a purpose-built accelerator for scale-out deployments. The RTX 4080 Mobile wins for client-side graphics, ray tracing, and portable compute where API compatibility and display output matter.

The data shows a clear split: the MI325X is a specification-driven compute accelerator with no benchmark validation in the database, while the RTX 4080 Mobile is a benchmark-verified mobile GPU with a complete feature set. Each wins in its intended domain, and neither overlaps meaningfully with the other's use case.