AMD Radeon RX 6750 XT vs NVIDIA Quadro M5000 Comparison

Head-to-Head Benchmarks

The recorded data contains two direct benchmark comparisons between the NVIDIA Quadro M5000 and the AMD Radeon RX 6750 XT. The results are split exactly one win each, but the margins tell very different stories.

In the Geekbench OpenCL test, the Quadro M5000 delivers a score of 29,481, while the RX 6750 XT manages 16,360. That is a delta of 80.2% in favor of the NVIDIA card. The Quadro M5000 is the older product, released in 2015, yet it holds a commanding lead in this compute workload. The OpenCL result is particularly notable because it is not a narrow victory; the Quadro finishes with a score nearly double that of its AMD rival. This aligns with the professional positioning of the Quadro line, where compute consistency and driver optimization for OpenCL workloads have historically been priorities.

The Geekbench Vulkan test flips the script completely. Here, the RX 6750 XT scores 98,089, while the Quadro M5000 posts 32,931. The delta is -66.4% from the perspective of the NVIDIA card, meaning the AMD part is roughly three times faster in this API. Vulkan is a modern, low-level graphics API, and the RDNA 2.0 architecture in the RX 6750 XT was designed with contemporary gaming and compute workloads in mind. The Quadro M5000, based on Maxwell 2.0, was never built for Vulkan’s explicit multi-threaded command model, and the benchmark data reflects that gap.

Averaging the two head-to-head results, the Quadro M5000 has an average benchmark score of 31,206 across all recorded tests, while the RX 6750 XT averages 26,011. The Quadro sits at the 76th percentile of all GPUs in the database, and its nearest rivals include the NVIDIA GRID M60-1Q (avg score 31,220, delta 0%), the NVIDIA GeForce RTX 4070 Ti SUPER (avg score 31,087, delta 0.4%), and the NVIDIA TITAN RTX (avg score 31,676, delta -1.5%). The RX 6750 XT, meanwhile, sits at the 71st percentile, with nearest rivals including the AMD Radeon R9 M395X (avg score 25,891, delta 0.5%), the AMD FirePro W7100 (avg score 25,856, delta 0.6%), and the NVIDIA GeForce RTX 3080 Ti Mobile (avg score 25,740, delta 1.1%).

The delta percentages against these rivals are small, all within 1.5%, which suggests that both cards are tightly clustered with their immediate peers. However, the two cards are not close to each other in overall average score; the Quadro M5000 leads by roughly 5,195 points, or about 20%. That gap is substantial, but it is driven almost entirely by the OpenCL result, which heavily favors the NVIDIA part.

Where Each One Wins

The use-case split is clear from the benchmark data. The NVIDIA Quadro M5000 wins in OpenCL compute workloads. The score of 29,481 versus 16,360 represents an 80.2% advantage. OpenCL is a cross-platform compute API used in professional applications such as rendering, scientific simulation, and video processing. The Quadro M5000, with its Maxwell architecture and 2,048 shading units, demonstrates that raw compute throughput in this specific API remains competitive even against a much newer GPU. The 5,200 million transistors on a 28 nm process and a die size of 398 mm² contribute to a transistor density of 13.1M per mm², but the architecture’s efficiency in OpenCL is what the data highlights.

The AMD Radeon RX 6750 XT wins decisively in Vulkan. The score of 98,089 versus 32,931, a delta of -66.4% for the NVIDIA card, indicates that the RX 6750 XT is the clear choice for Vulkan-based workloads. Vulkan is the API of choice for modern game engines, and it is also used in some compute applications that require low overhead and explicit control over the GPU. The RX 6750 XT’s RDNA 2.0 architecture, with 40 ray accelerators and 2,560 shading units, is built to handle Vulkan’s parallel command buffers efficiently. The Quadro M5000 has no dedicated ray accelerators, and its Vulkan driver support is a legacy implementation, so the performance gap is not surprising.

For users who prioritize professional compute tasks that rely on OpenCL, the Quadro M5000 is the stronger option based on the data. For users who need modern graphics API performance, particularly Vulkan, the RX 6750 XT is the only rational choice. The two cards are not interchangeable; they serve different workload profiles, and the benchmark results reinforce that distinction.

Architecture Differences

The two GPUs come from different architectural generations and design philosophies. The NVIDIA Quadro M5000 uses the GM204 chip, built on the Maxwell 2.0 architecture, fabricated on a 28 nm process at TSMC. The chip contains 5,200 million transistors on a die size of 398 mm², resulting in a transistor density of 13.1M per mm². The AMD Radeon RX 6750 XT uses the Navi 22 chip, based on RDNA 2.0, also fabricated at TSMC but on a 7 nm process. The Navi 22 die contains 17,200 million transistors on a smaller die of 335 mm², yielding a much higher transistor density of 51.3M per mm². The process node difference is significant: 28 nm versus 7 nm, which explains the density disparity.

The memory subsystems also differ. The Quadro M5000 has 8 GB of GDDR5 memory on a 256-bit bus, with a memory clock of 1653 MHz (6.6 Gbps effective) and a bandwidth of 211.6 GB/s. The RX 6750 XT has 12 GB of GDDR6 memory on a 192-bit bus, with a memory clock of 2250 MHz (18 Gbps effective) and a bandwidth of 432.0 GB/s. The RX 6750 XT offers 12 GB of capacity versus 8 GB, and its bandwidth is more than double the Quadro’s, at 432.0 GB/s versus 211.6 GB/s.

Compute resources are another major differentiator. The Quadro M5000 has 2,048 shading units, 128 texture mapping units, and 64 raster output units. The RX 6750 XT has 2,560 shading units, 160 TMUs, and 64 ROPs, plus 40 ray accelerators. The RX 6750 XT also supports FP16 compute with a 2:1 ratio, offering 26.62 TFLOPS of FP16, while the Quadro has no recorded FP16 capability. The FP32 throughput is 4.252 TFLOPS for the Quadro versus 13.31 TFLOPS for the RX 6750 XT, a more than threefold difference.

The clock speeds reflect the architectural differences. The Quadro M5000 runs at a base of 861 MHz and a boost of 1038 MHz. The RX 6750 XT runs at a base of 2150 MHz, a game clock of 2495 MHz, and a boost of 2600 MHz. The power draw is also different: the Quadro has a TDP of 150 W with a single 6-pin power connector, while the RX 6750 XT has a TDP of 250 W with a 6-pin plus an 8-pin connector. The suggested PSU is 450 W for the Quadro and 600 W for the RX 6750 XT.

The bus interface differs as well: PCIe 3.0 x16 for the Quadro versus PCIe 4.0 x16 for the RX 6750 XT. The Quadro supports DirectX 12 (12_1), OpenGL 4.6, and Vulkan 1.4. The RX 6750 XT supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4. Display outputs also vary: the Quadro offers 1x DVI and 4x DisplayPort 1.2, while the RX 6750 XT offers 1x HDMI 2.1 and 3x DisplayPort 1.4a.

FAQ

Q: Which GPU has a higher average benchmark score?

A: The NVIDIA Quadro M5000 has an average benchmark score of 31,206, while the AMD Radeon RX 6750 XT averages 26,011. The Quadro M5000 is 5,195 points higher, which is about 20% ahead.

Q: How do the two cards compare in Geekbench OpenCL?

A: The Quadro M5000 scores 29,481 in Geekbench OpenCL, while the RX 6750 XT scores 16,360. The Quadro leads by 80.2%.

Q: How do the two cards compare in Geekbench Vulkan?

A: The RX 6750 XT scores 98,089 in Geekbench Vulkan, while the Quadro M5000 scores 32,931. The RX 6750 XT leads by a delta of -66.4% from the NVIDIA card’s perspective, meaning it is roughly three times faster.

Q: What is the transistor density of each GPU?

A: The Quadro M5000 has a transistor density of 13.1M per mm² (5,200 million transistors on a 398 mm² die). The RX 6750 XT has a density of 51.3M per mm² (17,200 million transistors on a 335 mm² die).

Q: Which GPU has more memory and bandwidth?

A: The RX 6750 XT has 12 GB of GDDR6 memory with a bandwidth of 432.0 GB/s. The Quadro M5000 has 8 GB of GDDR5 memory with a bandwidth of 211.6 GB/s.

Q: Which GPU supports ray tracing?

A: The RX 6750 XT includes 40 ray accelerators. The Quadro M5000 has no ray accelerators listed in the database.

Specification Differences

| Specification | NVIDIA Quadro M5000 | AMD Radeon RX 6750 XT |

|----------------|---------------------|------------------------|

| Architecture | Maxwell 2.0 | RDNA 2.0 |

| Process Node | 28 nm | 7 nm |

| Transistors | 5,200 million | 17,200 million |

| Die Size | 398 mm² | 335 mm² |

| Transistor Density | 13.1M / mm² | 51.3M / mm² |

| Base Clock | 861 MHz | 2150 MHz |

| Boost Clock | 1038 MHz | 2600 MHz |

| Game Clock | N/A | 2495 MHz |

| Memory Clock | 6.6 Gbps effective | 18 Gbps effective |

| Memory Size | 8 GB | 12 GB |

| Memory Type | GDDR5 | GDDR6 |

| Memory Bus Width | 256 bit | 192 bit |

| Memory Bandwidth | 211.6 GB/s | 432.0 GB/s |

| Shading Units | 2048 | 2560 |

| TMUs | 128 | 160 |

| ROPs | 64 | 64 |

| Ray Accelerators | N/A | 40 |

| Pixel Rate | 66.43 GPixel/s | 166.4 GPixel/s |

| Texture Rate | 132.9 GTexel/s | 416.0 GTexel/s |

| FP32 | 4.252 TFLOPS | 13.31 TFLOPS |

| FP16 | N/A | 26.62 TFLOPS (2:1) |

| TDP | 150 W | 250 W |

| Power Connectors | 1x 6-pin | 1x 6-pin + 1x 8-pin |

| Suggested PSU | 450 W | 600 W |

| Bus Interface | PCIe 3.0 x16 | PCIe 4.0 x16 |

| Display Outputs | 1x DVI, 4x DisplayPort 1.2 | 1x HDMI 2.1, 3x DisplayPort 1.4a |

| DirectX | 12 (12_1) | 12 Ultimate (12_2) |

| Release Date | 2015-06-28 | 2022-03-02 |

| Predecessor | Quadro Kepler | Navi |

| Successor | Quadro Pascal | Navi III |

| Launch MSRP | N/A | 549 USD |

The Verdict

The data presents two GPUs with divergent strengths. The NVIDIA Quadro M5000 is the better choice for OpenCL-based compute workloads. Its score of 29,481 in Geekbench OpenCL, an 80.2% lead over the RX 6750 XT, is a decisive advantage. The Quadro M5000 also has a higher average benchmark score (31,206 versus 26,011) and a higher percentile ranking (76th versus 71st). It achieves this with a much lower TDP of 150 W, making it a more power-efficient option for compute tasks.

The AMD Radeon RX 6750 XT is the better choice for Vulkan workloads. Its score of 98,089 in Geekbench Vulkan, roughly three times the Quadro’s 32,931, demonstrates a clear superiority in modern graphics APIs. The RX 6750 XT also offers 12 GB of memory, 432.0 GB/s of bandwidth, 40 ray accelerators, and FP16 support, making it a more capable GPU for gaming and contemporary rendering pipelines. Its higher TDP of 250 W and suggested PSU of 600 W reflect its performance-oriented design.

Users who need professional compute performance in OpenCL, such as those running legacy simulation or rendering software, should select the Quadro M5000. Users who need modern graphics API performance, ray tracing, or higher memory capacity should select the RX 6750 XT. The two cards are not direct competitors in the same market segment; the Quadro M5000 is a professional workstation GPU from 2015, while the RX 6750 XT is a consumer gaming GPU from 2022. The benchmark data shows that each holds a clear edge in its respective domain, and the choice depends entirely on the workload.