AMD Radeon RX 6650M vs NVIDIA RTX PRO 5000 Blackwell Comparison

Where Each One Wins

The benchmark data presents a clear division between these two GPUs, though the contest is not balanced. The NVIDIA RTX PRO 5000 Blackwell wins both recorded head-to-head tests, leaving the AMD Radeon RX 6650M without a single benchmark victory in the database comparison. That said, the two cards occupy entirely different market positions, and the AMD part still demonstrates competence within its own performance tier.

The RTX PRO 5000 Blackwell is built for compute-heavy professional workloads. Its Geekbench OpenCL score of 254116 places it in the 98th percentile of all GPUs in the database, and its average benchmark score of 182109 confirms that it sustains high performance across multiple test scenarios. The card is not merely fast in one synthetic test; it delivers consistent, top-tier results that place it alongside enterprise accelerators like the NVIDIA A100 SXM4 80 GB, which trails by only 0.9 percent in average score.

The Radeon RX 6650M, by contrast, is a mobile part with an end-of-life production status. Its average benchmark score of 71768 places it in the 91st percentile, which is still respectable for a laptop GPU. Its nearest rivals include the NVIDIA TITAN X Pascal, which leads by only 0.5 percent, and the AMD Radeon Pro Vega 64, which leads by 0.8 percent. This suggests the RX 6650M sits in a well-populated competitive band where small percentage differences separate products. It wins no direct comparison here, but it is not an outlier at the bottom of the database either.

The use-case split is therefore straightforward. The RTX PRO 5000 Blackwell is for professionals who need maximum compute throughput, large memory capacity, and the ability to handle multiple demanding workloads without compromise. The RX 6650M is for portable systems where power efficiency and adequate performance matter more than raw capability. The data shows that the NVIDIA part dominates in absolute terms, but the AMD part remains viable in its intended mobile context.

Architecture Differences

The architectural gap between these two GPUs is substantial, and it explains much of the performance disparity. The RTX PRO 5000 Blackwell uses the GB202 chip based on Blackwell 2.0 architecture, fabricated by TSMC on a 5 nm process. The die measures 750 mm² and contains 92,200 million transistors, yielding a transistor density of 122.9 million per square millimeter. This is a massive, high-density chip designed for maximum throughput.

The Radeon RX 6650M uses the Navi 23 chip based on RDNA 2.0 architecture, also fabricated by TSMC but on a 7 nm process. The die is 237 mm² and contains 11,060 million transistors, for a density of 46.7 million per square millimeter. The process node difference alone explains a significant portion of the efficiency and density gap between the two designs.

The NVIDIA part carries 14,080 shading units, 440 texture mapping units, and 160 ROPs. It also includes 110 RT cores and 440 tensor cores, the latter being absent entirely from the AMD part. The tensor cores are critical for AI and machine learning workloads, which the RX 6650M cannot accelerate with dedicated hardware. The AMD GPU has 1,792 shading units, 112 TMUs, 64 ROPs, and 28 RT cores, which are far smaller numbers across every unit type.

Memory architecture also diverges sharply. The RTX PRO 5000 Blackwell features 48 GB of GDDR7 memory on a 384-bit bus, delivering 1.34 TB/s of bandwidth. The RX 6650M has 8 GB of GDDR6 memory on a 128-bit bus, providing 224.0 GB/s. The NVIDIA card offers six times the memory capacity and roughly six times the bandwidth, a decisive advantage for large datasets and high-resolution rendering.

The API support is identical on paper: both cards support DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4. However, the underlying feature sets differ because of the tensor cores and the much larger compute resources on the NVIDIA side. The RTX PRO 5000 Blackwell also uses a PCIe 5.0 x16 interface, while the RX 6650M uses PCIe 4.0 x8, which further limits the bandwidth available to the AMD part in systems that can supply data quickly.

Head-to-Head Benchmarks

The only two tests shared between these GPUs in the database are Geekbench OpenCL and Geekbench Vulkan, and the NVIDIA RTX PRO 5000 Blackwell wins both by a wide margin.

In Geekbench OpenCL, the RTX PRO 5000 Blackwell scores 254116 against 65800 for the RX 6650M, a delta of 286.2 percent. This means the NVIDIA card is nearly four times faster in raw OpenCL compute performance. The OpenCL test exercises general-purpose GPU compute, and the combination of more shading units, higher memory bandwidth, and tensor core acceleration contributes to this massive gap. A 286.2 percent lead is not a marginal difference; it represents a completely different performance class.

In Geekbench Vulkan, the NVIDIA card scores 282631 against 77735 for the AMD part, a delta of 263.6 percent. The Vulkan test is more graphics-oriented than OpenCL but still heavily dependent on raw throughput. The RTX PRO 5000 Blackwell again dominates, though the relative margin narrows slightly from the OpenCL result. This suggests the NVIDIA architecture scales its advantage across both compute and graphics workloads.

The average benchmark scores tell a similar story. The RTX PRO 5000 Blackwell averages 182109 across all recorded tests, while the RX 6650M averages 71768. That is a difference of approximately 154 percent in average performance. The NVIDIA card sits in the 98th percentile of all GPUs, while the AMD card sits in the 91st percentile. Both are above average, but the distance between them is enormous.

The nearest rival data reinforces this. The RTX PRO 5000 Blackwell trades blows with the NVIDIA A100 SXM4 80 GB, which is 0.9 percent ahead, and the RTX 5000 Ada Generation, which is 1.4 percent ahead. Meanwhile, the RX 6650M competes with the NVIDIA TITAN X Pascal, which is 0.5 percent ahead, and the AMD Radeon Pro Vega 64, which is 0.8 percent ahead. The two cards are not just different in performance; they are surrounded by entirely different competitor sets.

Specification Differences

The following specifications differ between the two GPUs, with all values taken directly from the recorded data.

The RTX PRO 5000 Blackwell uses the GB202 chip on a 5 nm process, while the RX 6650M uses Navi 23 on 7 nm. Transistor counts are 92,200 million versus 11,060 million, and die sizes are 750 mm² versus 237 mm². Transistor density is 122.9 million per square millimeter versus 46.7 million.

Clock speeds differ in structure. The NVIDIA card has a base clock of 1740 MHz and a boost clock of 2377 MHz, with no game clock recorded. The AMD card has a base clock of 2068 MHz, a boost clock of 2416 MHz, and a game clock of 2222 MHz. The AMD part has a higher base clock, but the NVIDIA card reaches a similar boost clock despite having vastly more compute units.

Memory configurations are entirely different. The NVIDIA card has 48 GB of GDDR7 on a 384-bit bus with 1.34 TB/s bandwidth. The AMD card has 8 GB of GDDR6 on a 128-bit bus with 224.0 GB/s bandwidth. Memory clock is recorded as 1750 MHz (28 Gbps effective) for NVIDIA and 1750 MHz (14 Gbps effective) for AMD.

Compute unit counts differ across every category. The NVIDIA card has 14,080 shading units, 440 TMUs, 160 ROPs, 110 RT cores, and 440 tensor cores. The AMD card has 1,792 shading units, 112 TMUs, 64 ROPs, and 28 RT cores, with no tensor cores.

Rates and throughput figures reflect the hardware differences. The NVIDIA card delivers 380.3 GPixel/s pixel rate, 1,045.9 GTexel/s texture rate, 66.94 TFLOPS FP32, and 66.94 TFLOPS FP16 at a 1:1 ratio. The AMD card delivers 154.6 GPixel/s, 270.6 GTexel/s, 8.659 TFLOPS FP32, and 17.32 TFLOPS FP16 at a 2:1 ratio.

Power and physical specifications also differ. The NVIDIA card has a TDP of 300 W, uses a dual-slot design, requires a single 16-pin power connector, and needs a 700 W suggested PSU. The AMD card has a TDP of 120 W, uses an IGP form factor, has no power connectors, and has no suggested PSU recorded. The NVIDIA card uses PCIe 5.0 x16, while the AMD card uses PCIe 4.0 x8. Display outputs are 4x DisplayPort 2.1b for NVIDIA and portable-device-dependent for AMD. The NVIDIA card measures 267 mm by 111 mm by 40 mm; no dimensions are recorded for the AMD part.

Production status differs as well: the RTX PRO 5000 Blackwell is active, while the RX 6650M is end-of-life. The NVIDIA card was released on 2025-03-17, and the AMD card on 2022-01-03. The NVIDIA card has a recorded launch MSRP of 5,099 USD, while no launch MSRP is recorded for the AMD card.

FAQ

Q: Which GPU is faster in Geekbench OpenCL?

A: The NVIDIA RTX PRO 5000 Blackwell scores 254116 versus 65800 for the AMD Radeon RX 6650M, a difference of 286.2 percent.

Q: How much faster is the NVIDIA card in Geekbench Vulkan?

A: The RTX PRO 5000 Blackwell scores 282631, while the RX 6650M scores 77735, giving the NVIDIA card a lead of 263.6 percent.

Q: What are the memory capacities of these two GPUs?

A: The RTX PRO 5000 Blackwell has 48 GB of GDDR7 memory on a 384-bit bus with 1.34 TB/s bandwidth. The RX 6650M has 8 GB of GDDR6 on a 128-bit bus with 224.0 GB/s bandwidth.

Q: Does the AMD Radeon RX 6650M have tensor cores?

A: No tensor cores are recorded for the RX 6650M. The RTX PRO 5000 Blackwell includes 440 tensor cores.

Q: What is the average benchmark score for each GPU?

A: The RTX PRO 5000 Blackwell averages 182109, placing it in the 98th percentile. The RX 6650M averages 71768, placing it in the 91st percentile.

Q: Which architecture does each GPU use?

A: The NVIDIA RTX PRO 5000 Blackwell uses Blackwell 2.0 architecture on a 5 nm process with the GB202 chip. The AMD Radeon RX 6650M uses RDNA 2.0 architecture on a 7 nm process with the Navi 23 chip.