AMD Radeon RX 6600S vs NVIDIA Quadro P2200 Comparison

Head-to-Head Benchmarks

The recorded data shows a decisive overall victory for the AMD Radeon RX 6600S, which wins 7 of the 8 head-to-head benchmark comparisons. The most striking result is in Geekbench OpenCL, where the AMD card scores 66,435 versus 32,344 for the NVIDIA Quadro P2200, a 105.4% advantage. This is the largest margin in either direction across the entire test suite, more than doubling the NVIDIA card’s compute output.

DirectX workloads also favor the AMD Radeon RX 6600S substantially. In PassMark DirectX 10, the AMD card scores 81 against 45 for the Quadro P2200, a 80% lead. PassMark DirectX 11 shows 105 versus 70, a 50% advantage. PassMark DirectX 12 results are 56 versus 33, giving the AMD card a 69.7% edge. The smaller gaps appear in legacy DirectX 9, where the AMD card leads 176 to 167, a 5.4% margin, and in PassMark GPU Compute, where the AMD card scores 4,879 versus 3,921, a 24.4% win.

The overall PassMark G3D score, which reflects the full graphics benchmark suite, strongly favors the AMD Radeon RX 6600S: 12,649 versus 9,364, a 35.1% advantage. This places the AMD part in the 49th percentile of all GPUs in the database, while the NVIDIA Quadro P2200 sits in the 44th percentile. The average benchmark score for the AMD card is 10,629, compared to 8,686 for the NVIDIA card.

The sole victory for the NVIDIA Quadro P2200 comes in PassMark G2D, a 2D graphics performance test. The NVIDIA card scores 881 versus 647 for the AMD Radeon RX 6600S, a 26.6% advantage. This is notable because it indicates that the Quadro P2200 maintains a clear edge in 2D rasterization and desktop compositing workloads, even though it loses decisively in every 3D and compute-oriented test.

Looking at the nearest rivals in the database, both cards cluster near similar performance tiers. The AMD Radeon RX 6600S has an average score 0.4% above the AMD Radeon R9 M275X and 1.4% above the AMD Radeon RX 550X, while trailing the NVIDIA GeForce GTX 560 Ti by 0.6% and the NVIDIA Quadro K2200 by 1.2%. The NVIDIA Quadro P2200 sits 1.1% above the AMD FirePro W5170M and 1.5% above the Intel Arc A380, while trailing the NVIDIA GeForce GTX 460 v2 and the NVIDIA GeForce RTX 3050 A Mobile by 0.7% each. These proximity scores contextualize the head-to-head results: the AMD card is performing near the top of its immediate rival pool, while the NVIDIA card is essentially mid-pack among its own nearest competitors.

Architecture Differences

The architectural divide between these two GPUs is substantial and explains the benchmark spread. The AMD Radeon RX 6600S uses the Navi 23 chip built on RDNA 2.0 architecture, fabricated on a 7 nm process at TSMC. The NVIDIA Quadro P2200 uses the GP106 chip on the older Pascal architecture, fabricated on a 16 nm process, also at TSMC. The process node difference is significant: the AMD card packs 11,060 million transistors into a 237 mm² die, yielding a transistor density of 46.7 million per square millimeter. The NVIDIA card contains 4,400 million transistors on a 200 mm² die, for a density of 22.0 million per square millimeter. This gives the AMD chip more than double the transistor density, a direct consequence of the newer manufacturing node.

The memory subsystems also differ in type and capacity. The AMD Radeon RX 6600S uses 4 GB of GDDR6 memory on a 128-bit bus, delivering 224.0 GB/s of bandwidth. The NVIDIA Quadro P2200 uses 5 GB of GDDR5X memory on a 160-bit bus, delivering 200.2 GB/s. Despite having 1 GB more memory, the NVIDIA card has lower memory bandwidth, which matters in bandwidth-bound workloads.

Clock speeds are markedly different. The AMD card runs at a base clock of 1700 MHz, a game clock of 1881 MHz, and a boost clock of 2000 MHz. The NVIDIA card has a base clock of 1000 MHz and a boost clock of 1493 MHz, with no game clock specified. The memory clocks also differ: the AMD card runs at 1750 MHz with 14 Gbps effective, while the NVIDIA card runs at 1251 MHz with 10 Gbps effective.

Compute resources show the AMD card with 1,792 shading units, 112 texture mapping units, and 64 render output units. The NVIDIA card has 1,280 shading units, 80 TMUs, and 40 ROPs. The AMD card also includes 28 ray tracing cores, a feature entirely absent from the Pascal-based NVIDIA card. Neither card includes tensor cores.

The resulting pixel and texture rates reflect these resource differences. The AMD Radeon RX 6600S achieves 128.0 GPixel/s and 224.0 GTexel/s, while the NVIDIA Quadro P2200 achieves 59.72 GPixel/s and 119.4 GTexel/s. Floating-point performance follows the same pattern: the AMD card delivers 7.168 TFLOPS FP32 and 14.34 TFLOPS FP16 (2:1 ratio), while the NVIDIA card delivers 3.822 TFLOPS FP32 and only 59.72 GFLOPS FP16 (1:64 ratio). The FP16 disparity is extreme, with the AMD card offering roughly 240 times the half-precision throughput.

API support also differs. The AMD Radeon RX 6600S supports DirectX 12 Ultimate (12_2) and Vulkan 1.4, while the NVIDIA Quadro P2200 supports DirectX 12 (12_1) and Vulkan 1.4. Both cards support OpenGL 4.6.

Where Each One Wins

The AMD Radeon RX 6600S is the clear choice for compute-heavy and 3D rendering workloads. Its 105.4% lead in Geekbench OpenCL indicates a massive advantage in general-purpose GPU compute, which is relevant for tasks like physics simulations, data processing, and any workload that leverages OpenCL. The 35.1% lead in PassMark G3D means the AMD card is substantially faster in real-world 3D graphics applications, including modern game engines and professional 3D visualization. The 24.4% win in PassMark GPU Compute reinforces the AMD card’s compute superiority.

For DirectX gaming and graphics API performance, the AMD Radeon RX 6600S wins across every DirectX version tested. The largest margins are in DirectX 10 and DirectX 12, with 80% and 69.7% leads respectively. Even in DirectX 9, where the absolute scores are closest, the AMD card still wins by 5.4%. This makes the AMD card a more capable option for both legacy and modern DirectX applications.

The NVIDIA Quadro P2200’s single win is in PassMark G2D, where it leads by 26.6%. This indicates that for 2D desktop workflows, such as multi-monitor productivity setups, document rendering, and UI-heavy applications, the NVIDIA card offers superior performance. The Quadro P2200 also has the advantage of 5 GB of memory versus 4 GB on the AMD card, which can be beneficial for holding larger textures or datasets in memory, even if the bandwidth is lower. Additionally, the NVIDIA card’s PCIe 3.0 x16 interface, while older, offers more lanes than the AMD card’s PCIe 4.0 x8 interface, which could matter for certain data-transfer patterns.

Specification Differences

The two cards differ across nearly every specification category. The AMD Radeon RX 6600S belongs to the Radeon RX 6000 series and uses the RDNA 2.0 architecture with the Navi 23 chip, while the NVIDIA Quadro P2200 uses the Pascal architecture with the GP106 chip. The AMD card is manufactured on a 7 nm process with 11,060 million transistors on a 237 mm² die, while the NVIDIA card uses a 16 nm process with 4,400 million transistors on a 200 mm² die. Transistor density is 46.7M per mm² for AMD and 22.0M per mm² for NVIDIA.

Clock specifications differ: AMD lists base, game, and boost clocks of 1700 MHz, 1881 MHz, and 2000 MHz respectively, while NVIDIA lists base and boost clocks of 1000 MHz and 1493 MHz with no game clock. Memory configurations differ in size (4 GB GDDR6 versus 5 GB GDDR5X), bus width (128-bit versus 160-bit), and bandwidth (224.0 GB/s versus 200.2 GB/s).

Compute unit counts differ: AMD has 1,792 shading units, 112 TMUs, 64 ROPs, and 28 ray tracing cores, while NVIDIA has 1,280 shading units, 80 TMUs, 40 ROPs, and no ray tracing cores. Pixel and texture rates are 128.0 GPixel/s and 224.0 GTexel/s for AMD, versus 59.72 GPixel/s and 119.4 GTexel/s for NVIDIA. FP32 performance is 7.168 TFLOPS for AMD versus 3.822 TFLOPS for NVIDIA, and FP16 performance is 14.34 TFLOPS versus 59.72 GFLOPS.

Power characteristics differ: the AMD card has an 80 W TDP with integrated (IGP) slot width and no power connectors, while the NVIDIA card has a 75 W TDP with single-slot width and no power connectors, but a suggested PSU of 250 W. Bus interfaces differ: PCIe 4.0 x8 for AMD versus PCIe 3.0 x16 for NVIDIA. Display outputs are portable-device-dependent for AMD, while NVIDIA provides 4x DisplayPort 1.4a.

Release dates differ: the AMD card launched on 2022-01-03, while the NVIDIA card launched on 2019-06-09. The AMD card’s predecessor is Polaris Mobile, while NVIDIA’s predecessor is Quadro Maxwell and its successor is Quadro Volta. Both cards are end-of-life. The NVIDIA card has physical dimensions of 201 mm (7.9 inches) in length and 111 mm (4.4 inches) in height; the AMD card’s dimensions are not specified.

FAQ

Q: Which GPU has higher overall average benchmark scores?

A: The AMD Radeon RX 6600S has an average benchmark score of 10,629, while the NVIDIA Quadro P2200 has an average score of 8,686.

Q: What is the largest performance gap between the two cards?

A: The largest gap is in Geekbench OpenCL, where the AMD Radeon RX 6600S scores 66,435 versus 32,344 for the NVIDIA Quadro P2200, a 105.4% difference.

Q: Does the NVIDIA Quadro P2200 win any benchmark?

A: Yes, the NVIDIA Quadro P2200 wins PassMark G2D with a score of 881 versus 647 for the AMD Radeon RX 6600S, a 26.6% advantage.

Q: How do the memory bandwidths compare?

A: The AMD Radeon RX 6600S provides 224.0 GB/s of bandwidth from 4 GB of GDDR6 on a 128-bit bus, while the NVIDIA Quadro P2200 provides 200.2 GB/s from 5 GB of GDDR5X on a 160-bit bus.

Q: Which card supports ray tracing?

A: Only the AMD Radeon RX 6600S supports ray tracing, with 28 ray tracing cores. The NVIDIA Quadro P2200 has no ray tracing cores.

Q: What are the FP16 performance figures for each card?

A: The AMD Radeon RX 6600S delivers 14.34 TFLOPS FP16 with a 2:1 ratio, while the NVIDIA Quadro P2200 delivers 59.72 GFLOPS FP16 with a 1:64 ratio.