GPU Comparison

The AMD Radeon RX 6600S and NVIDIA Quadro 6000 represent two vastly different eras of GPU design, separated by over a decade of architectural evolution. The benchmark data shows a decisive victory for the modern AMD mobile part, with the RX 6600S delivering a Geekbench OpenCL score of 66,435 against the Quadro 6000’s 9,846, a commanding 574.7% advantage. While the Quadro 6000 was a professional workstation heavyweight in its time, the comparison highlights how far GPU compute performance has come, with the RX 6600S offering over six times the raw compute throughput of its older rival.

Head-to-Head Benchmarks

The sole head-to-head benchmark available, Geekbench OpenCL, provides a stark illustration of generational performance disparity. The AMD Radeon RX 6600S scores 66,435 points, while the NVIDIA Quadro 6000 manages only 9,846 points. This translates to a delta of 574.7% in favor of the AMD part, meaning the RX 6600S is nearly seven times faster in this compute-oriented workload. This is not a marginal improvement; it is a complete overhaul of performance expectations, driven by the fundamental architectural and process technology differences between the two cards.

The RX 6600S’s FP32 throughput is rated at 7.168 TFLOPS, dwarfing the Quadro 6000’s 1,027.7 GFLOPS (approximately 1.03 TFLOPS). This raw compute advantage is the primary driver of the OpenCL result. The AMD card’s pixel rate of 128.0 GPixel/s and texture rate of 224.0 GTexel/s also vastly exceed the Quadro’s 16.07 GPixel/s and 32.14 GTexel/s, respectively. These figures suggest that the RX 6600S would not only dominate in compute but also in traditional rasterization workloads, had those benchmarks been available for comparison.

The Quadro 6000’s average benchmark score sits at 9,846, placing it in the 47th percentile of all GPUs. Its nearest rivals include the NVIDIA Quadro M2000M (avg score 9,832, delta 0.1%), AMD FirePro W5000 (9,803, delta 0.4%), and NVIDIA GeForce GTX 1070 (9,780, delta 0.7%). The RX 6600S, by contrast, achieves an average benchmark score of 10,629, placing it in the 49th percentile, with rivals like the AMD Radeon R9 M275X (10,582, delta 0.4%) and NVIDIA GeForce GTX 560 Ti (10,690, delta -0.6%). The percentile ranking shows both cards are near the median of all GPUs, but the RX 6600S’s higher absolute score in the single shared test is what matters for this comparison.

FAQ

Q: Which GPU has the higher Geekbench OpenCL score?

A: The AMD Radeon RX 6600S scores 66,435, which is 574.7% higher than the NVIDIA Quadro 6000’s score of 9,846.

Q: What is the difference in memory bandwidth between the two cards?

A: The RX 6600S has a memory bandwidth of 224.0 GB/s, while the Quadro 6000 has a bandwidth of 143.4 GB/s, giving the AMD card a significant advantage in data throughput.

Q: How do the transistor counts and die sizes compare?

A: The RX 6600S uses 11,060 million transistors on a 237 mm² die, resulting in a density of 46.7M / mm². The Quadro 6000 uses 3,100 million transistors on a much larger 529 mm² die, with a density of only 5.9M / mm².

Q: Does the Quadro 6000 support modern APIs like Vulkan?

A: No. The Quadro 6000 has no Vulkan support listed, and its DirectX support is limited to version 12 (11_0). The RX 6600S supports DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4.

Q: Which card has more shading units?

A: The AMD Radeon RX 6600S has 1,792 shading units, compared to the NVIDIA Quadro 6000’s 448 shading units. The RX 6600S also has 112 TMUs and 64 ROPs, versus the Quadro’s 56 TMUs and 48 ROPs.

Q: What is the power consumption difference?

A: The RX 6600S has a TDP of 80 W, while the Quadro 6000 has a TDP of 204 W. The Quadro also requires a 550 W suggested PSU and dual power connectors (1x 6-pin + 1x 8-pin), whereas the RX 6600S is an IGP with no power connectors.

Where Each One Wins

The AMD Radeon RX 6600S is the clear winner in every measurable performance category. Its dominance in the Geekbench OpenCL test, combined with its vastly superior pixel rate, texture rate, and FP32 throughput, makes it the obvious choice for any compute-intensive or modern gaming workload. The RX 6600S also wins on efficiency, delivering its performance at an 80 W TDP compared to the Quadro 6000’s 204 W. For tasks like OpenCL acceleration, modern DirectX 12 Ultimate gaming, or any application leveraging Vulkan, the RX 6600S is categorically superior.

The NVIDIA Quadro 6000’s only potential advantage lies in its legacy professional ecosystem. Its 6 GB of GDDR5 memory on a 384-bit bus, while slower in bandwidth (143.4 GB/s), offers more capacity than the RX 6600S’s 4 GB. For older professional applications that were optimized for Fermi-era hardware and require more memory than the RX 6600S can provide, the Quadro 6000 might still function, but it will do so at a fraction of the speed. Its dual-slot form factor and 248 mm length also indicate a desktop workstation orientation, while the RX 6600S is a portable IGP. However, given the massive performance delta, there is no scenario where the Quadro 6000 wins on speed; it only wins on legacy memory capacity.

Specification Differences

The two cards differ across almost every specification. The AMD Radeon RX 6600S uses 4 GB of GDDR6 memory on a 128-bit bus, while the NVIDIA Quadro 6000 uses 6 GB of GDDR5 on a 384-bit bus. The RX 6600S’s memory clock is 1750 MHz (14 Gbps effective), versus the Quadro’s 747 MHz (3 Gbps effective). The RX 6600S has a base clock of 1700 MHz and boost clock of 2000 MHz, while the Quadro lists no base or boost clocks. The RX 6600S has 1,792 shading units, 112 TMUs, and 64 ROPs, while the Quadro has 448 shading units, 56 TMUs, and 48 ROPs. The RX 6600S also includes 28 RT cores, which the Quadro lacks entirely.

The bus interface differs significantly: the RX 6600S uses PCIe 4.0 x8, while the Quadro 6000 uses PCIe 2.0 x16. The power requirements are also starkly different, with the RX 6600S being an 80 W IGP with no power connectors, versus the Quadro’s 204 W TDP, dual-slot design, and 1x 6-pin + 1x 8-pin power connectors. The Quadro’s display outputs are fixed as 1x DVI, 2x DisplayPort, and 1x S-Video, whereas the RX 6600S’s outputs are portable device dependent. The physical dimensions also differ, with the Quadro measuring 248 mm in length and 111 mm in height, while the RX 6600S has no listed dimensions due to its IGP nature.

Architecture Differences

The architectural gap between these two GPUs is generational. The AMD Radeon RX 6600S is built on the RDNA 2.0 architecture, using the Navi 23 chip, fabricated on TSMC’s 7 nm process. It contains 11,060 million transistors on a 237 mm² die, achieving a density of 46.7M / mm². The NVIDIA Quadro 6000 is based on the Fermi architecture, using the GF100 chip, fabricated on a 40 nm process. It contains just 3,100 million transistors on a much larger 529 mm² die, resulting in a density of only 5.9M / mm². This means the RX 6600S packs nearly four times the transistors into less than half the die area.

The RX 6600S features a modern feature set including 28 RT cores for hardware ray tracing, support for DirectX 12 Ultimate (12_2), and Vulkan 1.4. The Quadro 6000 has no RT cores, no Vulkan support, and only DirectX 12 (11_0) compatibility. The RX 6600S also supports FP16 compute at 14.34 TFLOPS (2:1 ratio), while the Quadro 6000 lists no FP16 capability. The RX 6600S is part of the Navi Mobile (RX 6000M) generation, released in January 2022, while the Quadro 6000 is from the Quadro Fermi (x000) generation, released in December 2010. The Quadro’s successor was the Quadro Kepler, while the RX 6600S has no listed successor, as it is an end-of-life product from a newer family. The process node alone, 7 nm versus 40 nm, explains a substantial portion of the performance and efficiency gap, as the smaller node allows for higher clocks and better power efficiency.