AMD Radeon RX 6400 vs NVIDIA RTX PRO 6000 Blackwell Server Comparison

The AMD Radeon RX 6400 and the NVIDIA RTX PRO 6000 Blackwell Server occupy opposite ends of the hardware spectrum, yet the benchmark database places them as near-statistical twins in average score. The RX 6400 averages 6001 points across its suite, while the RTX PRO 6000 averages 5996 points, a delta of just 0.1%. This odd pairing stems from the RTX PRO 6000 having only a single recorded 3DMark Steel Nomad DX12 result, while the RX 6400’s average includes ten varied tests. In that one direct head-to-head benchmark, the NVIDIA card scores 5996 versus the AMD card’s 176, a 97.1% difference. The rest of the comparison is a study in contrast: the RX 6400 is a 6 nm, 53 W, end-of-life entry card, while the RTX PRO 6000 is a 5 nm, 600 W, active server workhorse.

Head-to-Head Benchmarks

The only shared benchmark between the two cards is 3DMark Steel Nomad DX12, and the result is not close. The NVIDIA RTX PRO 6000 Blackwell Server scores 5996, while the AMD Radeon RX 6400 scores 176. That is a delta of -97.1% for the AMD part. In raw terms, the RTX PRO 6000 delivers over 34 times the frame throughput in this DirectX 12 workload. The RX 6400’s 176-point result is consistent with its position in the 35th percentile of all GPUs, while the RTX PRO 6000 sits at the 34th percentile. The near-identical percentile rankings obscure the magnitude of this single-test gap, which is the only direct comparison the data supports.

Looking at the broader benchmark picture, the RX 6400 has ten recorded scores, with its strongest showing in Geekbench OpenCL at 32011 points. Its Passmark G3D score is 7673, and its Passmark G2D score is 722. Compute-oriented tests are weaker: Passmark GPU Compute yields 2812 points, and DirectX 12 in Passmark yields just 30 points. The RTX PRO 6000, by contrast, has only the one Steel Nomad result. The NVIDIA card’s average score of 5996 is therefore essentially that single number, while the RX 6400’s average of 6001 is pulled up by its strong OpenCL and Vulkan results. The Vulkan score for the RX 6400 is 16372, and its DirectX 11 Passmark score is 70, while DirectX 10 and DirectX 9 scores are 54 and 93, respectively.

The nearest rivals list confirms this odd statistical clustering. The RX 6400’s closest neighbor is the NVIDIA GeForce GTX 770M at 6000 points (delta 0%), followed by the RTX PRO 6000 at 5996 (delta 0.1%), the AMD FirePro W4100 at 5987 (delta 0.2%), and the NVIDIA Quadro K4000M at 5986 (delta 0.3%). The RTX PRO 6000’s own rival list mirrors this: GTX 770M at 6000 (delta -0.1%), RX 6400 at 6001 (delta -0.1%), FirePro W4100 at 5987 (delta 0.2%), and Quadro K4000M at 5986 (delta 0.2%). The data shows both cards within 0.3% of the same four rivals, yet their hardware specifications could not diverge more.

The Verdict

The data does not support a single winner; it supports two buyers. The AMD Radeon RX 6400 wins on efficiency and practicality: it draws 53 W, requires no power connectors, fits in a single slot, and carries a launch MSRP of 159 USD. The NVIDIA RTX PRO 6000 Blackwell Server wins on raw capability: 96 GB of GDDR7 memory, 1.79 TB/s bandwidth, and 126.0 TFLOPS FP32. The 3DMark result gives the NVIDIA card a decisive 97.1% victory in that specific test, but the RX 6400 counters with a 35th percentile ranking versus the RTX PRO 6000’s 34th percentile. For a user needing a low-profile, low-power card for basic display output or legacy workloads, the RX 6400 is the data-backed choice. For anyone running server-class compute or massive memory-bound tasks, the RTX PRO 6000 is the only option that matches the requirements.

The average benchmark scores tell a misleading story. The RX 6400’s 6001 average across ten tests is not comparable to the RTX PRO 6000’s 5996 across one test. The RX 6400’s best result, Geekbench OpenCL at 32011, dwarfs its Steel Nomad score by a factor of 182. The RTX PRO 6000 has no such spread because only one test is recorded. The verdict hinges on workload: the RX 6400 is a 768-shader, 4 GB card for light tasks, while the RTX PRO 6000 is a 24064-shader, 96 GB monster for heavy computation. Neither card is a substitute for the other.

Where Each One Wins

The RX 6400 wins in scenarios requiring minimal power draw and physical footprint. Its 53 W TDP means no auxiliary power connectors are needed, and the single-slot design fits in compact chassis. The 4 GB GDDR6 memory on a 64-bit bus delivers 128.0 GB/s, sufficient for 1080p-class workloads or as a display adapter. The 6 nm process node and 107 mm² die size make it a low-cost entry point, as reflected in its 159 USD launch MSRP. The card’s end-of-life status suggests it is a legacy option, but its 35th percentile ranking indicates it still outperforms a majority of all GPUs in the database.

The RTX PRO 6000 wins in every performance-critical category. Its 96 GB GDDR7 memory with 512-bit bus width yields 1.79 TB/s bandwidth, a 14-fold increase over the RX 6400’s 128.0 GB/s. The 24064 shading units and 752 TMUs provide 1,968.0 GTexel/s texture rate versus the RX 6400’s 111.4 GTexel/s. The 188 RT cores and 752 tensor cores are absent from the AMD card entirely. The 5 nm process packs 92,200 million transistors into a 750 mm² die, achieving a transistor density of 122.9M per mm². The dual-slot design with a single 16-pin connector and 1000 W suggested PSU indicates a power-hungry but capable server component.

The PCIe interface also separates them: the RX 6400 uses PCIe 4.0 x4, while the RTX PRO 6000 uses PCIe 5.0 x16. The latter offers 16 lanes of the newest standard, while the former makes do with four lanes of the previous generation. Display outputs differ, with the RX 6400 offering one HDMI 2.1 and one DisplayPort 1.4a, while the RTX PRO 6000 provides four DisplayPort 2.1b outputs. For multi-display server configurations, the NVIDIA card is clearly superior.

FAQ

Q: Which card has a higher average benchmark score?

A: The AMD Radeon RX 6400 averages 6001 points across ten benchmarks, while the NVIDIA RTX PRO 6000 Blackwell Server averages 5996 points from a single benchmark. The difference is 5 points, or 0.1%.

Q: How do the two cards compare in 3DMark Steel Nomad DX12?

A: The NVIDIA RTX PRO 6000 scores 5996, while the AMD RX 6400 scores 176. The NVIDIA card wins by a delta of -97.1% from the AMD card’s perspective.

Q: What is the memory capacity difference?

A: The RX 6400 has 4 GB of GDDR6 memory on a 64-bit bus, while the RTX PRO 6000 has 96 GB of GDDR7 memory on a 512-bit bus. The bandwidth difference is 128.0 GB/s versus 1.79 TB/s.

Q: Which card has more shading units?

A: The RTX PRO 6000 has 24064 shading units, while the RX 6400 has 768. The NVIDIA card also has 752 tensor cores and 188 RT cores, features the AMD card lacks entirely.

Q: What is the TDP and power requirement for each?

A: The RX 6400 has a 53 W TDP with no power connectors and a 250 W suggested PSU. The RTX PRO 6000 has a 600 W TDP with a single 16-pin connector and a 1000 W suggested PSU.

Q: Which card is currently in production?

A: The AMD RX 6400 is listed as end-of-life, while the NVIDIA RTX PRO 6000 is listed as active. The RX 6400 launched on 2022-01-18, and the RTX PRO 6000 launched on 2025-03-17.

Architecture Differences

The architectural divide is absolute. The AMD Radeon RX 6400 uses the Navi 24 chip built on RDNA 2.0 architecture, fabricated on a 6 nm TSMC process. It contains 5,400 million transistors on a 107 mm² die, yielding a transistor density of 50.5M per mm². The NVIDIA RTX PRO 6000 Blackwell Server uses the GB202 chip built on Blackwell 2.0 architecture, also from TSMC but on a 5 nm process. It packs 92,200 million transistors into a 750 mm² die, achieving 122.9M per mm² density. The process node advantage (5 nm vs 6 nm) and die size difference (750 mm² vs 107 mm²) explain the massive transistor count disparity.

The memory subsystems are generations apart. The RX 6400 uses 4 GB of GDDR6 at 2000 MHz (16 Gbps effective) on a 64-bit bus for 128.0 GB/s. The RTX PRO 6000 uses 96 GB of GDDR7 at 1750 MHz (28 Gbps effective) on a 512-bit bus for 1.79 TB/s. The bus width is 8 times larger, and the memory clock is faster in effective terms. The compute resources follow suit: the RX 6400 has 768 shading units, 48 TMUs, 32 ROPs, and 12 RT cores, while the RTX PRO 6000 has 24064 shading units, 752 TMUs, 192 ROPs, 188 RT cores, and 752 tensor cores.

Clock speeds show a different pattern. The RX 6400 has a higher base clock at 1923 MHz versus the RTX PRO 6000’s 1590 MHz, but the NVIDIA card boosts higher at 2617 MHz versus 2321 MHz. The RX 6400 also lists a game clock of 2039 MHz, which the RTX PRO 6000 does not specify. The FP32 throughput is where the gap widest: the RX 6400 delivers 3.565 TFLOPS, while the RTX PRO 6000 delivers 126.0 TFLOPS. FP16 performance is identical to FP32 on the NVIDIA card (126.0 TFLOPS, 1:1 ratio), while the RX 6400 achieves 7.130 TFLOPS at a 2:1 ratio.

Pixel and texture rates reinforce the hierarchy. The RX 6400 renders 74.27 GPixel/s and 111.4 GTexel/s; the RTX PRO 6000 renders 502.5 GPixel/s and 1,968.0 GTexel/s. The API support is identical on paper: both offer DirectX 12 Ultimate (12_2), OpenGL 4.6, and Vulkan 1.4. Physical dimensions differ, with the RTX PRO 6000 measuring 267 mm in length, 111 mm in height, and 40 mm in width, while the RX 6400 has no recorded dimensions. The RTX PRO 6000 is dual-slot with a 16-pin connector; the RX 6400 is single-slot with no connectors. The NVIDIA card is the clear architectural leader in every measurable way except power draw, where the RX 6400’s 53 W is a fraction of the RTX PRO 6000’s 600 W.