AMD Radeon R7 M340 vs NVIDIA Quadro K4000 Comparison

Head-to-Head Benchmarks

The database records two shared benchmark tests between the NVIDIA Quadro K4000 and the AMD Radeon R7 M340, and the results are unambiguous. The Quadro K4000 wins both head-to-head comparisons, with its largest margin coming in the Geekbench OpenCL test. There, the NVIDIA card scores 6816 against the AMD card's 4932, a lead of 38.2 percent. That is a substantial gap in raw compute throughput, reflecting the Quadro's much larger execution resource pool. The Vulkan test tells a similar story, though the margin narrows slightly: the Quadro K4000 scores 6964 while the Radeon R7 M340 scores 5193, a 34.1 percent advantage for the NVIDIA part. In both cases, the Quadro K4000 is not just ahead, it is ahead by roughly a third or more of the AMD card's own score.

Looking at the broader context from the database's average benchmark scores, the overall picture remains consistent. The Quadro K4000 averages 5982 across all recorded tests, while the Radeon R7 M340 averages 5063. That is a difference of 919 points, or about 18.2 percent higher for the NVIDIA part. The percentile rankings also favor the Quadro: it sits at the 34th percentile against all GPUs in the database, while the Radeon R7 M340 sits at the 30th percentile. Neither card is a top-tier performer by modern standards, but the Quadro K4000 is clearly the stronger of the two in every measured workload.

When placed against its nearest rivals in the database, the Quadro K4000's position is interesting. Its average score of 5982 is essentially tied with the NVIDIA Quadro K4000M (5986, a 0.1 percent deficit), the AMD FirePro W4100 (5987, a 0.1 percent deficit), and the AMD Radeon HD 8750M (5970, a 0.2 percent advantage). Even the NVIDIA RTX PRO 6000 Blackwell Server, a drastically newer and more powerful part, only shows a 0.2 percent higher average score in this particular database entry (5996). This suggests the Quadro K4000's benchmark numbers are clustered in a narrow band, and its performance class is well established.

The Radeon R7 M340's nearest rivals are similarly tight. Its average of 5063 matches the AMD Radeon R7 240 exactly (0 percent delta), sits 0.6 percent ahead of the AMD FirePro W4170M (5034), 0.9 percent ahead of the AMD Radeon R5 M430 (5018), and 1.3 percent ahead of the AMD Radeon R7 Graphics (4998). So the AMD part is at the top of its immediate peer group, but that peer group is a full tier below where the Quadro K4000 operates.

FAQ

Q: Which GPU wins in OpenCL performance?

A: The NVIDIA Quadro K4000 wins decisively. It scores 6816 in Geekbench OpenCL, while the AMD Radeon R7 M340 scores 4932. That is a 38.2 percent advantage for the NVIDIA card.

Q: Is there any benchmark where the AMD Radeon R7 M340 comes out ahead?

A: No. In the database's head-to-head results, the AMD card wins zero tests. The Quadro K4000 wins both the OpenCL and Vulkan benchmarks, with margins of 38.2 percent and 34.1 percent respectively.

Q: How do these two cards compare to their closest competitors?

A: The Quadro K4000 sits in a tight cluster with its nearest rivals, all within 0.2 percent of its 5982 average score. The Radeon R7 M340 is similarly grouped, with its nearest rivals ranging from a 0 percent delta to a 1.3 percent delta around its 5063 average.

Q: What is the average benchmark score for each card?

A: The NVIDIA Quadro K4000 has an average benchmark score of 5982. The AMD Radeon R7 M340 has an average benchmark score of 5063.

Q: Which card has the higher overall percentile ranking?

A: The Quadro K4000 ranks at the 34th percentile among all GPUs in the database. The Radeon R7 M340 ranks at the 30th percentile.

Q: Does the newer release date of the AMD card help it in benchmarks?

A: The recorded data says no. The Radeon R7 M340 was released in 2015, over two years after the Quadro K4000's 2013 launch, but it still trails in every shared test. The Quadro K4000 maintains a 34 to 38 percent lead in the head-to-head measurements.

The Verdict

The data is straightforward: the NVIDIA Quadro K4000 is the faster GPU in every measured workload. It holds a 38.2 percent OpenCL lead and a 34.1 percent Vulkan lead over the AMD Radeon R7 M340. Its average benchmark score is 919 points higher, and it ranks 4 percentile points higher in the overall database distribution. If the choice is purely about compute performance from the available benchmark data, the Quadro K4000 is the clear pick.

However, the Radeon R7 M340 is not without its own context. It sits at the top of its immediate rival group, matching the AMD Radeon R7 240 exactly and leading the AMD FirePro W4170M, AMD Radeon R5 M430, and AMD Radeon R7 Graphics by small margins. So within its own performance class, it is a competitive part. But that class is simply lower than the Quadro K4000's. The AMD card's 30th percentile ranking versus the NVIDIA card's 34th percentile confirms this hierarchy across the entire database.

For a user choosing between these two specific cards, the benchmark results point firmly to the Quadro K4000. It offers roughly a third more performance in the shared tests, which is a meaningful difference for any compute or graphics workload. The Radeon R7 M340 would only make sense if the platform constraints or feature requirements favor it, but based purely on recorded performance, the NVIDIA card wins.

Specification Differences

The two cards differ across nearly every core specification. The NVIDIA Quadro K4000 uses a 192-bit memory bus with 3 GB of GDDR5 memory, delivering 134.8 GB/s of bandwidth. The AMD Radeon R7 M340 uses a 64-bit bus with 2 GB of DDR3 memory, delivering 16.00 GB/s. That is an 8.4x difference in memory bandwidth, which directly impacts texture-heavy and resolution-heavy workloads.

The compute resources also diverge sharply. The Quadro K4000 has 768 shading units, 64 texture mapping units, and 24 raster output units. The Radeon R7 M340 has 320 shading units, 20 TMUs, and 8 ROPs. Pixel rate is 12.96 GPixel/s for the NVIDIA card versus 8.168 GPixel/s for the AMD card. Texture rate is 51.84 GTexel/s versus 20.42 GTexel/s. Floating-point performance (FP32) is 1,244.2 GFLOPS for the Quadro versus 653.4 GFLOPS for the Radeon, a nearly 2x gap.

Clock behavior differs as well. The Quadro K4000 has no recorded base or boost clock, but its memory runs at 1404 MHz with 5.6 Gbps effective. The Radeon R7 M340 has a base clock of 943 MHz, a boost clock of 1021 MHz, and memory at 1000 MHz with 2 Gbps effective. The AMD card is a mobile-oriented part with a PCIe 3.0 x8 interface, while the NVIDIA card uses PCIe 2.0 x16. The Quadro is a single-slot card measuring 241 mm in length and 111 mm in height, with a 1x 6-pin power connector and a 250 W suggested PSU. The AMD card has no recorded dimensions, slot width, or power connector data.

Architecture Differences

The architectural split is generational and fundamental. The NVIDIA Quadro K4000 is built on the Kepler architecture, using the GK106 chip fabricated on a 28 nm process at TSMC. It packs 2,540 million transistors into a 221 mm² die, for a transistor density of 11.5 million per mm². The AMD Radeon R7 M340 uses the GCN 3.0 architecture with the Meso chip, also on a 28 nm TSMC process, but with 1,550 million transistors on a smaller 125 mm² die, achieving a slightly higher density of 12.4 million per mm².

The memory architecture is a major differentiator. The Quadro K4000 uses GDDR5 with a 192-bit bus, while the Radeon R7 M340 uses DDR3 with a 64-bit bus. This is not just a capacity difference (3 GB versus 2 GB), but a fundamental bandwidth limitation. The Quadro's 134.8 GB/s versus the Radeon's 16.00 GB/s means the NVIDIA card can feed its shaders far more effectively.

The API support also differs. The Quadro K4000 supports DirectX 12 (11_0), OpenGL 4.6, and Vulkan 1.2.175. The Radeon R7 M340 supports DirectX 12 (12_0), OpenGL 4.6, and Vulkan 1.2.170. The AMD card has a higher DirectX feature level, but the NVIDIA card has a slightly newer Vulkan version. The Radeon also records FP16 performance at 653.4 GFLOPS (1:1 with FP32), while the Quadro has no recorded FP16 data, indicating it likely lacks dedicated half-rate compute.

The Quadro K4000 is a professional workstation card from the Quadro Kepler generation, with a release date in 2013, a predecessor in Quadro Fermi, and a successor in Quadro Maxwell. The Radeon R7 M340 comes from the Gem System R7 M300 generation, released in 2015, with a predecessor in Solar System and a successor in Polaris Mobile. The NVIDIA card carries a launch MSRP of 1,269 USD; the AMD card has no recorded launch MSRP.

Where Each One Wins

The NVIDIA Quadro K4000 wins everywhere the database has measurements. In compute workloads, its 38.2 percent OpenCL lead and 34.1 percent Vulkan lead make it the stronger choice for general-purpose GPU compute, including OpenCL and Vulkan-based applications. Its higher FP32 throughput (1,244.2 GFLOPS versus 653.4 GFLOPS) supports this, as does its far higher texture rate (51.84 GTexel/s versus 20.42 GTexel/s) and pixel rate (12.96 GPixel/s versus 8.168 GPixel/s). For rendering, image processing, or any task that stresses memory bandwidth, the Quadro's 134.8 GB/s versus 16.00 GB/s is a decisive advantage.

The AMD Radeon R7 M340 does not win any recorded benchmark, so its advantages are structural rather than performance-based. It has a smaller die (125 mm² versus 221 mm²) and fewer transistors (1,550 million versus 2,540 million), which likely means lower power draw, though the database does not record a TDP for the AMD card. It uses PCIe 3.0 x8, which is a newer bus standard than the Quadro's PCIe 2.0 x16. It also supports DirectX 12 (12_0) versus the Quadro's DirectX 12 (11_0), which could matter for certain modern gaming or compute features that require the higher feature level. Its FP16 throughput is explicitly recorded at 653.4 GFLOPS, which may be useful for workloads that can exploit half-precision math.

The practical use-case split is clear. If the workload is compute-heavy, bandwidth-hungry, or requires professional-grade rendering, the Quadro K4000 is the only rational choice based on the data. If the workload is a lightweight mobile scenario where the smaller die, newer bus interface, and higher DirectX feature level are more relevant than raw throughput, the Radeon R7 M340 could be considered. But for any performance-critical task, the benchmark results favor the NVIDIA card by a wide margin.