AMD Radeon Pro WX 9100 vs NVIDIA GeForce RTX 4090 Comparison

AMD Radeon Pro WX 9100 vs NVIDIA GeForce RTX 4090 is a mismatch in nearly every measurable category. The RTX 4090 wins both available head-to-head benchmarks by massive margins, while the WX 9100 trails by 73.9% and 79.9% respectively. Despite both cards launching at the same MSRP, the architectural gulf between 2017’s Vega 10 and 2022’s Ada Lovelace is decisive.

Head-to-Head Benchmarks

The data is unambiguous. In Geekbench OpenCL, the NVIDIA GeForce RTX 4090 scores 255,416 against the AMD Radeon Pro WX 9100’s 66,605. That is a delta of -73.9% for the AMD card, meaning the RTX 4090 delivers roughly 3.8 times the raw compute performance. The margin is even starker in Geekbench Vulkan, where the RTX 4090 reaches 271,631 versus 54,711 for the WX 9100 — a -79.9% delta, or nearly five times the score. No benchmark in the pack shows the WX 9100 winning; the RTX 4090 claims both head-to-head tests.

These are not close contests. The RTX 4090’s OpenCL advantage alone exceeds the WX 9100’s entire average benchmark score across all tests. The WX 9100’s average benchmark score is 64,212, while the RTX 4090’s single best OpenCL result is 255,416. Even the RTX 4090’s weaker Vulkan score of 271,631 dwarfs the AMD card’s best result of 71,319 in Geekbench Metal — a test the NVIDIA card does not even have a comparable result for in this pack.

The percentile rankings tell a similar story. The WX 9100 sits at the 89th percentile of all GPUs, while the RTX 4090 is at the 88th percentile. That near-parity in percentile is misleading given the raw scores; the WX 9100’s percentile is buoyed by its specialized workstation profile, but the head-to-head deltas reveal the true performance hierarchy. The RTX 4090’s nearest rivals include the Intel Arc Pro A60 (within 0%) and AMD Radeon Pro W6600M (2.5% behind), while the WX 9100’s closest competitors are the NVIDIA CMP 30HX (0.6% behind) and AMD Radeon RX 9060 XT LP (0.6% behind).

Where Each One Wins

The RTX 4090 wins every benchmark category where both cards have data. In OpenCL and Vulkan, the NVIDIA card is categorically superior. The FP32 throughput tells the hardware story: the RTX 4090 delivers 82.58 TFLOPS versus 12.29 TFLOPS for the WX 9100 — a 6.7x gap. Texture rate follows the same pattern, with the RTX 4090 at 1,290.2 GTexel/s versus 384.0 GTexel/s for the AMD card. Pixel rate is similarly lopsided: 443.5 GPixel/s versus 96.00 GPixel/s.

The WX 9100’s only potential advantages are structural rather than performance-based. It uses HBM2 memory with a 2048-bit bus, yielding 483.8 GB/s bandwidth, while the RTX 4090 uses GDDR6X on a 384-bit bus for 1.01 TB/s. The AMD card’s memory bandwidth is half that of the NVIDIA card, but its HBM2 implementation offers a wider bus — a design choice suited to certain workstation workloads. However, no benchmark in the pack validates any real-world win for the WX 9100 in memory-sensitive tasks.

For compute-heavy applications like rendering or simulation, the RTX 4090’s 16,384 shading units and 512 tensor cores provide overwhelming parallel throughput. The WX 9100’s 4,096 shading units and no tensor or RT cores limit it to legacy GCN-era workloads. The RTX 4090 also supports DirectX 12 Ultimate (12_2) and Vulkan 1.4, whereas the WX 9100 tops out at DirectX 12 (12_1) and Vulkan 1.3.

Architecture Differences

The two cards come from different eras and foundries. The AMD Radeon Pro WX 9100 uses the Vega 10 chip on a 14 nm process from GlobalFoundries, with 12,500 million transistors on a 495 mm² die. The NVIDIA GeForce RTX 4090 uses the AD102 chip on a 5 nm process from TSMC, packing 76,300 million transistors into a 609 mm² die. The transistor density difference is stark: 25.3M per mm² for AMD versus 125.3M per mm² for NVIDIA — a 5x density advantage for the newer process.

Memory configurations diverge completely. The WX 9100 has 16 GB of HBM2 on a 2048-bit bus, while the RTX 4090 has 24 GB of GDDR6X on a 384-bit bus. The RTX 4090’s 1.01 TB/s bandwidth is more than double the WX 9100’s 483.8 GB/s. Clock speeds also favor NVIDIA: the RTX 4090 boosts to 2520 MHz versus 1500 MHz for the AMD card.

Compute feature sets reflect the generational gap. The RTX 4090 includes 128 RT cores and 512 tensor cores, enabling hardware ray tracing and AI acceleration — neither of which exists on the WX 9100. FP16 performance highlights the design philosophy: the RTX 4090 achieves 82.58 TFLOPS at a 1:1 ratio with FP32, while the WX 9100’s 24.58 TFLOPS FP16 is only a 2:1 ratio over its FP32. The RTX 4090 also supports PCIe 4.0 x16 versus PCIe 3.0 x16 on the AMD card.

FAQ

Q: Which card has higher raw compute performance?

A: The RTX 4090 scores 255,416 in Geekbench OpenCL and 271,631 in Vulkan, versus 66,605 and 54,711 for the WX 9100, respectively.

Q: Do both cards support the same DirectX version?

A: No, the RTX 4090 supports DirectX 12 Ultimate (12_2), while the WX 9100 is limited to DirectX 12 (12_1).

Q: What is the memory capacity and type difference?

A: The WX 9100 has 16 GB of HBM2, while the RTX 4090 has 24 GB of GDDR6X.

Q: Which card has more shading units?

A: The RTX 4090 has 16,384 shading units, compared to 4,096 on the WX 9100.

Q: Are there any benchmarks where the WX 9100 wins?

A: No, the head-to-head data shows the RTX 4090 winning both available tests, and the WX 9100 has zero wins in the comparison.

Q: What is the launch MSRP of each card?

A: Both cards launched at 1,599 USD.

Specification Differences

| Specification | AMD Radeon Pro WX 9100 | NVIDIA GeForce RTX 4090 |

|---------------|------------------------|-------------------------|

| Architecture | GCN 5.0 | Ada Lovelace |

| Process Node | 14 nm | 5 nm |

| Foundry | GlobalFoundries | TSMC |

| Transistors | 12,500 million | 76,300 million |

| Die Size | 495 mm² | 609 mm² |

| Transistor Density | 25.3M / mm² | 125.3M / mm² |

| Base Clock | 1200 MHz | 2235 MHz |

| Boost Clock | 1500 MHz | 2520 MHz |

| Memory Size | 16 GB | 24 GB |

| Memory Type | HBM2 | GDDR6X |

| Memory Bus | 2048 bit | 384 bit |

| Memory Bandwidth | 483.8 GB/s | 1.01 TB/s |

| Shading Units | 4096 | 16384 |

| TMUs | 256 | 512 |

| ROPs | 64 | 176 |

| RT Cores | None | 128 |

| Tensor Cores | None | 512 |

| Pixel Rate | 96.00 GPixel/s | 443.5 GPixel/s |

| Texture Rate | 384.0 GTexel/s | 1,290.2 GTexel/s |

| FP32 | 12.29 TFLOPS | 82.58 TFLOPS |

| FP16 | 24.58 TFLOPS (2:1) | 82.58 TFLOPS (1:1) |

| TDP | 230 W | 450 W |

| Slot Width | Dual-slot | Triple-slot |

| Power Connectors | 1x 6-pin + 1x 8-pin | 1x 16-pin |

| Suggested PSU | 550 W | 850 W |

| Bus Interface | PCIe 3.0 x16 | PCIe 4.0 x16 |

| Display Outputs | 6x mini-DisplayPort 1.4a | 1x HDMI 2.1, 3x DisplayPort 1.4a |

| DirectX | 12 (12_1) | 12 Ultimate (12_2) |

| Vulkan | 1.3 | 1.4 |

| Dimensions | 267 mm (10.5 in) | 304 mm (12 in) |

| Height | 111 mm (4.4 in) | 137 mm (5.4 in) |

| Width | N/A | 61 mm (2.4 in) |

The Verdict

The choice is clear for any compute-focused buyer: the NVIDIA GeForce RTX 4090 dominates the AMD Radeon Pro WX 9100 in every benchmark with shared data. The RTX 4090’s OpenCL score is 3.8x higher, and its Vulkan score is nearly 5x higher. The 5 nm TSMC process, 16,384 shading units, and 82.58 TFLOPS FP32 performance leave the WX 9100’s 14 nm GCN design in a different performance class. The RTX 4090 also offers RT cores, tensor cores, and newer API support, making it the superior choice for modern workloads.

The WX 9100’s advantages are limited to its HBM2 memory with a wider 2048-bit bus and its lower 230 W TDP, which may appeal to legacy workstation environments with specific power or thermal constraints. Its six mini-DisplayPort outputs also suggest a niche multi-display setup. However, the WX 9100 is end-of-life, and its 89th percentile ranking reflects historical context rather than current competitiveness.

For anyone choosing between these two today, the RTX 4090 is the only rational pick. Its 24 GB of GDDR6X, 1.01 TB/s bandwidth, and 450 W power envelope deliver performance that the WX 9100 cannot approach. The equal launch MSRP of 1,599 USD makes the comparison even more lopsided — the RTX 4090 offers generationally superior technology at the same price point. The WX 9100 should only be considered for hardware-specific compatibility with older GCN-era software stacks. Otherwise, the RTX 4090 wins outright.